IJERPH, Vol. 17, Pages 1320: The Association between Metabolically Healthy Obesity, Cardiovascular Disease, and All-Cause Mortality Risk in Asia: A Systematic Review and Meta-Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17041320 Authors: Ming-Yuan Huang Mu-Yi Wang Yu-Sheng Lin Chien-Ju Lin Kai Lo I-Jen Chang Ting-Yao Cheng Szu-Ying Tsai Hsin-Hao Chen Chien-Yu Lin Shu Jung Liu Kuo-Liong Chien Tzu-Lin Yeh ...
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IJMS, Vol. 21, Pages 1360: Molecular Evidences for the Interactions of Auxin, Gibberellin, and Cytokinin in Bent Peduncle Phenomenon in Rose (Rosa sp.) International Journal of Molecular Sciences doi: 10.3390/ijms21041360 Authors: Weikun Jing Shuai Zhang Youwei Fan Yinglong Deng Chengpeng Wang Jingyun Lu Xiaoming Sun Nan Ma Muhammad Owais Shahid Yonghong Li Xiaofeng Zhou In roses (Rosa sp.), peduncle morphology is an important ornamental feature. The common...
IJMS, Vol. 21, Pages 1361: Zinc Finger Proteins in the Human Fungal Pathogen Cryptococcus neoformans
IJMS, Vol. 21, Pages 1361: Zinc Finger Proteins in the Human Fungal Pathogen Cryptococcus neoformans International Journal of Molecular Sciences doi: 10.3390/ijms21041361 Authors: Yuan-Hong Li Tong-Bao Liu Zinc is one of the essential trace elements in eukaryotes and it is a critical structural component of a large number of proteins. Zinc finger proteins (ZNFs) are zinc-finger domain-containing proteins stabilized by bound zinc ions and they form the most abundant proteins, serving...
IJMS, Vol. 21, Pages 1363: Bioinformatics Approaches to the Understanding of Molecular Mechanisms in Antimicrobial Resistance International Journal of Molecular Sciences doi: 10.3390/ijms21041363 Authors: Pieter-Jan Van Camp David B. Haslam Aleksey Porollo Antimicrobial resistance (AMR) is a major health concern worldwide. A better understanding of the underlying molecular mechanisms is needed. Advances in whole genome sequencing and other high-throughput unbiased instrumental...
IJMS, Vol. 21, Pages 1359: Regulatory Mechanisms of Mitochondrial Function and Cardiac Aging International Journal of Molecular Sciences doi: 10.3390/ijms21041359 Authors: Ruizhu Lin Risto Kerkelä Aging is a major risk factor for cardiovascular diseases (CVDs), the major cause of death worldwide. Cardiac myocytes, which hold the most abundant mitochondrial population, are terminally differentiated cells with diminished regenerative capacity in the adult. Cardiomyocyte mitochondrial...
IJMS, Vol. 21, Pages 1358: The Impact of MNRI Therapy on the Levels of Neurotransmitters Associated with Inflammatory Processes International Journal of Molecular Sciences doi: 10.3390/ijms21041358 Authors: Tatiana V. Tatarinova Trina Deiss Lorri Franckle Susan Beaven Jeffrey Davis The neurotransmitter levels of representatives from five different diagnosis groups were tested before and after participation in the MNRI®—Masgutova Neurosensorimotor Reflex...
IJMS, Vol. 21, Pages 1357: Tinkering Cis Motifs Jigsaw Puzzle Led to Root-Specific Drought-Inducible Novel Synthetic Promoters International Journal of Molecular Sciences doi: 10.3390/ijms21041357 Authors: Aysha Jameel Muhammad Noman Weican Liu Naveed Ahmad Fawei Wang Xiaowei Li Haiyan Li Following an in-depth transcriptomics-based approach, we first screened out and analyzed (in silico) cis motifs in a group of 63 drought-inducible genes (in soybean). Six novel synthetic...
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JCM, Vol. 9, Pages 558: Atrial Ectopy Increases Asynchronous Activation of the Endo- and Epicardium at the Right Atrium Journal of Clinical Medicine doi: 10.3390/jcm9020558 Authors: van der Does Kharbanda Teuwen Knops Kik Bogers de Groot The predisposition of atrial extrasystoles (AES) to trigger cardiac tachyarrhythmia may arise from intramural conduction disorders causing endo-epicardial asynchrony (EEA). This study aimed to determine whether spontaneous AES...
JCM, Vol. 9, Pages 554: Is Hematopoietic Stem Cell Transplantation Required to Unleash the Full Potential of Immunotherapy in Acute Myeloid Leukemia? Journal of Clinical Medicine doi: 10.3390/jcm9020554 Authors: Abadir Gasiorowski Silveira Larsen Clark From monoclonal antibodies (mAbs) to Chimeric Antigen Receptor (CAR) T cells, immunotherapies have enhanced the efficacy of treatments against B cell malignancies. The same has not been true for Acute Myeloid Leukemia...
JCM, Vol. 9, Pages 557: Neutrophil-Lymphocyte Ratio in Patients with Acute Heart Failure Predicts In-Hospital and Long-Term Mortality Journal of Clinical Medicine doi: 10.3390/jcm9020557 Authors: Cho Cho Lee Ki Jeon Hwang Chae Baek Kang Choi Yoo Kim Kim Oh The application of a simple blood test to predict prognosis in acute heart failure (AHF) patients is not well established. Neutrophil-lymphocyte ratio (NLR) is inexpensive and easy...
JCM, Vol. 9, Pages 556: Microperimetric Biofeedback Training after Successful Inverted Flap Technique for Large Macular Hole Journal of Clinical Medicine doi: 10.3390/jcm9020556 Authors: Sborgia Niro Tritto Albano Sborgia Sborgia Donghia Giancipoli Coassin Pastore Giuliani Lorenzi Romano Boscia Alessio Background: Despite the high closure rate of large macular hole (LMH) after surgery, visual recovery is often worse than expected....
JCM, Vol. 9, Pages 555: Longitudinal Relationships between Asthma-Specific Quality of Life and Asthma Control in Children; The Influence of Chronic Rhinitis Journal of Clinical Medicine doi: 10.3390/jcm9020555 Authors: van Vliet Essers Winkens Heynens Muris Jöbsis Dompeling Abstract: Managing pediatric asthma includes optimizing both asthma control and asthma-specific quality of life (QoL). However, it is unclear to what extent asthma-specific QoL is related...
JCM, Vol. 9, Pages 559: Fluorescent Light Energy (FLE) Acts on Mitochondrial Physiology Improving Wound Healing Journal of Clinical Medicine doi: 10.3390/jcm9020559 Authors: Letizia Ferroni Michela Zago Simone Patergnani Shannon E. Campbell Lise Hébert Michael Nielsen Carlotta Scarpa Franco Bassetto Paolo Pinton Barbara Zavan Fluorescent light energy (FLE) has been used to treat various injured tissues in a non-pharmacological and non-thermal fashion. It was...
JCM, Vol. 9, Pages 553: Recurrent Campylobacter Enteritis in Patients with Hypogammaglobulinemia: Review of the Literature Journal of Clinical Medicine doi: 10.3390/jcm9020553 Authors: Najjar Paluca Loukidis Tarr Recurrent Campylobacter enteritis is a well-recorded complication of primary hypogammaglobulinemia but has only rarely been reported with other types of immunodeficiency, and no cases have been reported after rituximab-associated secondary hypogammaglobulinemia....
JCM, Vol. 9, Pages 552: Bortezomib Treatment Modulates Autophagy in Multiple Myeloma Journal of Clinical Medicine doi: 10.3390/jcm9020552 Authors: Giuseppe Di Lernia Patrizia Leone Antonio Giovanni Solimando Alessio Buonavoglia Ilaria Saltarella Roberto Ria Paolo Ditonno Nicola Silvestris Lucilla Crudele Angelo Vacca Vito Racanelli Although the introduction of bortezomib as a therapeutic strategy has improved the overall survival of multiple myeloma (MM)...
JCM, Vol. 9, Pages 551: How We Manage Bone Marrow Edema—An Interdisciplinary Approach Journal of Clinical Medicine doi: 10.3390/jcm9020551 Authors: Sebastian F. Baumbach Vanessa Pfahler Susanne Bechtold-Dalla Pozza Isa Feist-Pagenstert Julian Fürmetz Andrea Baur-Melnyk Ulla C. Stumpf Maximilian M. Saller Andreas Straube Ralf Schmidmaier Jan Leipe Bone marrow edema (BME) is a descriptive term for a common finding in magnetic resonance imaging (MRI). Although...
JCM, Vol. 9, Pages 550: Combining Novel Biomarkers for Risk Stratification of Two-Year Cardiovascular Mortality in Patients with ST-Elevation Myocardial Infarction Journal of Clinical Medicine doi: 10.3390/jcm9020550 Authors: Naufal Zagidullin Lukas J. Motloch Diana Gareeva Aysilu Hamitova Irina Lakman Ilja Krioni Denis Popov Rustem Zulkarneev Vera Paar Kristen Kopp Peter Jirak Vladimir Ishmetov Uta C. Hoppe Eduard Tulbaev Valentin Pavlov ST-elevation...
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Life, Vol. 10, Pages 18: Getting Beyond the Toy Domain. Meditations on David Deamer’s “Assembling Life” Life doi: 10.3390/life10020018 Authors: William Bains David Deamer has written another book, Assembling Life, on the origin of life. It is unapologetically polemic, presenting Deamer’s view that life originated in fresh water hydrothermal fields on volcanic islands on early Earth, arguing that this provided a unique environment not just for organic chemistry but for the self-assembling...
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Medicina, Vol. 56, Pages 83: Inter-and Intra-Examiner Reliability of Supraspinatus Muscle Tendon Palpation: A Cross-Sectional Study by Ultrasonography Medicina doi: 10.3390/medicina56020083 Authors: Naranjo-Cinto Falcon-Machado Garrido-Marin Senin-Camargo Jacome-Pumar Fernandez-Matias Pecos-Martin Gallego-Izquierdo Background and objectives: Palpation is an inherent and basic skill of health professionals—particularly manual therapists who base...
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Membranes, Vol. 10, Pages 31: Chemically Crosslinked Sulfonated Polyphenylsulfone (CSPPSU) Membranes for PEM Fuel Cells Membranes doi: 10.3390/membranes10020031 Authors: Je-Deok Kim Akihiro Ohira Hidenobu Nakao Sulfonated polyphenylsulfone (SPPSU) with a high ion exchange capacity (IEC) was synthesized using commercially available polyphenylsulfone (PPSU), and a large-area (16 × 18 cm2) crosslinked sulfonated polyphenylsulfone (CSPPSU) membrane was prepared. In addition,...
Membranes, Vol. 10, Pages 30: Creating Supported Plasma Membrane Bilayers Using Acoustic Pressure Membranes doi: 10.3390/membranes10020030 Authors: Erdinc Sezgin Dario Carugo Ilya Levental Eleanor Stride Christian Eggeling Model membrane systems are essential tools for the study of biological processes in a simplified setting to reveal the underlying physicochemical principles. As cell-derived membrane systems, giant plasma membrane vesicles (GPMVs) constitute an intermediate...
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Microorganisms, Vol. 8, Pages 278: Differential Potential of Phytophthora capsici Resistance Mechanisms to the Fungicide Metalaxyl in Peppers Microorganisms doi: 10.3390/microorganisms8020278 Authors: Wang Liu Han Li Qu Gao : Metalaxyl is one of the main fungicides used to control pepper blight caused by Phytophthora capsici. Metalaxyl resistance of P. capsici, caused by the long-term intense use of this fungicide, has become one of the most serious challenges facing...
Microorganisms, Vol. 8, Pages 279: Diversity of Bacterial Biosynthetic Genes in Maritime Antarctica Microorganisms doi: 10.3390/microorganisms8020279 Authors: Rego Sousa Santos Pascoal Canário Leão Magalhães Bacterial natural products (NPs) are still a major source of new drug leads. Polyketides (PKs) and non-ribosomal peptides (NRP) are two pharmaceutically important families of NPs and recent studies have revealed Antarctica to harbor endemic polyketide synthase...
Microorganisms, Vol. 8, Pages 274: Anti-Contamination Strategies for Yeast Fermentations Microorganisms doi: 10.3390/microorganisms8020274 Authors: Seo Park Jung Ryu Kim Yeasts are very useful microorganisms that are used in many industrial fermentation processes such as food and alcohol production. Microbial contamination of such processes is inevitable, since most of the fermentation substrates are not sterile. Contamination can cause a reduction of the final product...
Microorganisms, Vol. 8, Pages 276: Measles: An Overview of a Re-Emerging Disease in Children and Immunocompromised Patients Microorganisms doi: 10.3390/microorganisms8020276 Authors: Misin Antonello Bella Campisciano Zanotta Giacobbe Comar Luzzati Despite the availability of a safe and effective vaccine, in 2018, around 350,000 measles cases were reported worldwide, which resulted in an estimate of 142,300 deaths from measles. Additionally, in 2017, global...
Microorganisms, Vol. 8, Pages 275: Arginine Catabolic Mobile Element in Evolution and Pathogenicity of the Community-Associated Methicillin-Resistant Staphylococcus aureus Strain USA300 Microorganisms doi: 10.3390/microorganisms8020275 Authors: Wu Conly McClure Kurwa Zhang USA300 is a predominant community-associated methicillin-resistant Staphylococcus aureus strain which carries an arginine catabolic mobile element (ACME). ACME contains potential virulence factors...
Microorganisms, Vol. 8, Pages 277: Diverse Microbial Community Profiles of Propionate-Degrading Cultures Derived from Different Sludge Sources of Anaerobic Wastewater Treatment Plants Microorganisms doi: 10.3390/microorganisms8020277 Authors: Puengrang Suraraksa Prommeenate Boonapatcharoen Cheevadhanarak Tanticharoen Kusonmano Anaerobic digestion (AD) has been used for wastewater treatment and production of renewable energy or biogas. Propionate accumulation...
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Molecules, Vol. 25, Pages 916: Opuntia Fruits as Food Enriching Ingredient, the First Step towards New Functional Food Products Molecules doi: 10.3390/molecules25040916 Authors: Anna Oniszczuk Agnieszka Wójtowicz Tomasz Oniszczuk Arkadiusz Matwijczuk Ahlem Dib Ewa Markut-Miotła Prickly pear (Opuntia ficus indica (L.) Mill.) is a rich source of vitamins C, B1, B2, A, and E, minerals such as calcium, potassium, magnesium, iron, and phosphorus, as well as bioactive substances,...
Molecules, Vol. 25, Pages 914: Regioselective Monobromination of Phenols with KBr and ZnAl–BrO3−–Layered Double Hydroxides Molecules doi: 10.3390/molecules25040914 Authors: Wang Feng Zhang Hu The regioselective mono-bromination of phenols has been successfully developed with KBr and ZnAl–BrO3−–layered double hydroxides (abbreviated as ZnAl–BrO3−–LDHs) as brominating reagents. The para site is much favorable and...
Molecules, Vol. 25, Pages 913: Identification of Secondary Metabolites from Aspergillus Pachycristatus by Untargeted UPLC-ESI-HRMS/MS and Genome Mining Molecules doi: 10.3390/molecules25040913 Authors: Perlatti Lan Jiang An Bills Aspergillus pachycristatus is an industrially important fungus for the production of the antifungal echinocandin B and is closely related to model organism A. nidulans. Its secondary metabolism is largely unknown except for the production of...
Molecules, Vol. 25, Pages 915: Dialkylketones in Paperboard Food Contact Materials—Method of Analysis in Fatty Foods and Comparative Migration into Liquid Simulants Versus Foodstuffs Molecules doi: 10.3390/molecules25040915 Authors: Antía Lestido-Cardama Ángela Störmer Roland Franz Dialkyl diketene dimers are used as sizing agents in the manufacture of paper and board for food contact applications to increase wetting stability. Unbound residues can hydrolyze and decarboxylate into...
Molecules, Vol. 25, Pages 910: Removal of Volatile Phenols From Wine Using Crosslinked Cyclodextrin Polymers Molecules doi: 10.3390/molecules25040910 Authors: Chao Dang Vladimir Jiranek Dennis K. Taylor Kerry L. Wilkinson Volatile phenols have been implicated as contributors to off-odors associated with taints from bushfire smoke and microbial spoilage. Various methods for the amelioration of off-odors have been evaluated, but to date, they have not included cyclodextrin (CD)...
Molecules, Vol. 25, Pages 912: A New Family of Diverse Skin Peptides from the Microhylid Frog Genus Phrynomantis Molecules doi: 10.3390/molecules25040912 Authors: Raaymakers Stijlemans Martin Zaman Ballet Martel Pasmans Roelants A wide range of frogs produce skin poisons composed of bioactive peptides for defence against pathogens, parasites and predators. While several frog families have been thoroughly screened for skin-secreted peptides, others, like the...
Molecules, Vol. 25, Pages 909: Flow Synthesis of Biologically-Relevant Compound Libraries Molecules doi: 10.3390/molecules25040909 Authors: Luque Navarro Lanari Flow chemistry is one of the most prominent enabling technologies that has greatly shaped the way chemists’ approach organic synthesis. Specifically, in drug discovery, the advantages of flow techniques over batch procedures allow the rapid and efficient assembly of compound libraries to be tested for biological...
Molecules, Vol. 25, Pages 911: Selected Fungal Natural Products with Antimicrobial Properties Molecules doi: 10.3390/molecules25040911 Authors: Jakubczyk Dussart Fungal natural products and their effects have been known to humankind for hundreds of years. For example, toxic ergot alkaloids produced by filamentous fungi growing on rye poisoned thousands of people and livestock throughout the Middle Ages. However, their later medicinal applications, followed by the discovery of the...
Molecules, Vol. 25, Pages 907: Supramolecular Sandwiches: Halogen-Bonded Coformers Direct [2+2] Photoreactivity in Two-Component Cocrystals Molecules doi: 10.3390/molecules25040907 Authors: Quentin C. Swenson R. MacGillivray The halogen-bond (X-bond) donors 1,3- and 1,4-diiodotetrafluorobenzene (1,3-di-I-tFb and 1,4-di-I-tFb, respectively) form cocrystals with trans-1,2-bis(2-pyridyl)ethylene (2,2′-bpe) assembled by N···I X-bonds. In...
Molecules, Vol. 25, Pages 905: Iron-Catalysed C(sp2)-H Borylation Enabled by Carboxylate Activation Molecules doi: 10.3390/molecules25040905 Authors: Luke Britton Jamie H. Docherty Andrew P. Dominey Stephen P. Thomas Arene C(sp2)-H bond borylation reactions provide rapid and efficient routes to synthetically versatile boronic esters. While iridium catalysts are well established for this reaction, the discovery and development of methods using Earth-abundant alternatives is limited...
Molecules, Vol. 25, Pages 906: Unsymmetrically Substituted Dibenzo[b,f][1,5]-diazocine-6,12(5H,11H)dione—A Convenient Scaffold for Bioactive Molecule Design Molecules doi: 10.3390/molecules25040906 Authors: Bieszczad Garbicz Trzybiński Mielecki Woźniak Grzesiuk Mieczkowski A novel approach for the synthesis of unsymmetrically substituted dibenzo[b,f][1,5]diazocine-6,12(5H,11H)diones has been developed. This facile three-step method uses variously substituted...
Molecules, Vol. 25, Pages 908: Traditional Yellow Dyes Used in the 21st Century in Central Iran: The Knowledge of Master Dyers Revealed by HPLC-DAD and UHPLC-HRMS/MS Molecules doi: 10.3390/molecules25040908 Authors: Sharif Nabais Melo Oliveira This work provides new knowledge on natural yellows used in Iran. Seven biological sources were selected based on interviews with dye masters in Isfahan workshops (Iran). Delphinium semibarbatum, Eremostachys laevigata, Prangos ferulacea,...
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