Antibiotics, Vol. 9, Pages 82: Correction: Saeed, A., et al. Incidence of Vancomycin-Resistant Phenotype of the Methicillin-Resistant Staphylococcus aureus Isolated from a Tertiary Care Hospital in Lahore. Antibiotics 2020, 9, 3. Antibiotics doi: 10.3390/antibiotics9020082 Authors: Saeed Ahsan Nawaz Iqbal Rehman Ijaz Staphylococcus aureus (S. aureus)-associated infections are one of the major threats to public health. The aim of the present study was to determine...
Thu Feb 13, 2020 02:00
Antibiotics, Vol. 9, Pages 83: Marie-Joelle Virolle Antibiotics doi: 10.3390/antibiotics9020083 Authors: Virolle Antibiotics are often considered as weapons conferring a competitive advantage to their producers in their ecological niche. However, since these molecules are produced in specific environmental conditions, notably phosphate limitation that triggers a specific metabolic state, they are likely to play important roles in the physiology of the producing bacteria that have been...
Thu Feb 13, 2020 02:00
Antibiotics, Vol. 9, Pages 81: Antibiotic Consumption and Microbiological Epidemiology in Surgery Departments: Results from a Single Study Center Antibiotics doi: 10.3390/antibiotics9020081 Authors: Dana Carmen Zaha Simona Bungau Diana Uivarosan Delia Mirela Tit Teodor Andrei Maghiar Octavian Maghiar Carmen Pantis Ovidiu Fratila Marius Rus Cosmin Mihai Vesa The spectrum and antibiotic sensitivity of isolated strains vary between departments, hospitals, countries;...
Thu Feb 13, 2020 02:00
Antibiotics, Vol. 9, Pages 80: Genomic Characterization of New Variant of Hydrogen Sulfide (H2S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China † Antibiotics doi: 10.3390/antibiotics9020080 Authors: Silpak Biswas Mohammed Elbediwi Guimin Gu Min Yue Colistin is considered to be a ‘last-resort’ antimicrobial for the treatment of multidrug-resistant Gram-negative bacterial infections. Identification of Enterobacteriaceae,...
Thu Feb 13, 2020 02:00
Antioxidants, Vol. 9, Pages 153: Layered Double Hydroxide Nanoparticles to Overcome the Hydrophobicity of Ellagic Acid: An Antioxidant Hybrid Material Antioxidants doi: 10.3390/antiox9020153 Authors: Muráth Szerlauth Sebők Szilágyi Ellagic acid (EA), a polyphenolic antioxidant of poor water solubility, was intercalated into biocompatible layered double hydroxide (LDH) nanoparticles by the coprecipitation method. Structural investigation of the composite revealed that the...
Thu Feb 13, 2020 02:00
Antioxidants, Vol. 9, Pages 152: The Implication of Chemotypic Variation on the Anti-Oxidant and Anti-Cancer Activities of Sutherlandia frutescens (L.) R.Br. (Fabaceae) from Different Geographic Locations Antioxidants doi: 10.3390/antiox9020152 Authors: Samkele Zonyane Olaniyi A. Fawole Chris la Grange Maria A. Stander Umezuruike L. Opara Nokwanda P. Makunga Extracts of Sutherlandia frutescens (cancer bush) exhibit considerable qualitative and quantitative chemical variability...
Thu Feb 13, 2020 02:00
Arts, Vol. 9, Pages 22: The Construction of the Great Synagogue in Stockholm, 1860–1870: A Space for Jewish and Swedish-Christian Dialogues Arts doi: 10.3390/arts9010022 Authors: Maja Hultman The construction of the Great Synagogue in Stockholm during the 1860s initiated Jewish communal debates on the position and public presence of Jews in the Swedish pre-emancipatory society. An investigation into the construction process not only reveals various Jewish opinions on the sacred building,...
Thu Feb 13, 2020 02:00
Atmosphere, Vol. 11, Pages 201: Study of Realistic Urban Boundary Layer Turbulence with High-Resolution Large-Eddy Simulation Atmosphere doi: 10.3390/atmos11020201 Authors: Mikko Auvinen Simone Boi Antti Hellsten Topi Tanhuanpää Leena Järvi This study examines the statistical predictability of local wind conditions in a real urban environment under realistic atmospheric boundary layer conditions by means of Large-Eddy Simulation (LES). The computational domain features a...
Thu Feb 13, 2020 02:00
Atmosphere, Vol. 11, Pages 199: Comparison of Different Techniques to Calculate Properties of Atmospheric Turbulence from Low-Resolution Data Atmosphere doi: 10.3390/atmos11020199 Authors: Marta Wacławczyk Amoussou S. Gozingan Jackson Nzotungishaka Moein Mohammadi Szymon P. Malinowski In this work we study different techniques to estimate basic properties of turbulence, that is its characteristic velocity and length scale from low-resolution data. The methods are based on...
Thu Feb 13, 2020 02:00
Atmosphere, Vol. 11, Pages 200: Operational Modelling of Umbrella Cloud Growth in a Lagrangian Volcanic Ash Transport and Dispersion Model Atmosphere doi: 10.3390/atmos11020200 Authors: Helen N. Webster Benjamin J. Devenish Larry G. Mastin David J. Thomson Alexa R. Van Eaton Large explosive eruptions can result in the formation of an umbrella cloud which rapidly expands, spreading ash out radially from the volcano. The lateral spread by the intrusive gravity current dominates...
Thu Feb 13, 2020 02:00
Atmosphere, Vol. 11, Pages 198: Inter-Comparison of Ensemble Forecasts for Low Level Wind Shear Against Local Analyses Data over Jeju Area Atmosphere doi: 10.3390/atmos11020198 Authors: Lee Ryoo Han Choi Kim Ensemble verification of low-level wind shear (LLWS) is an important issue in airplane landing operations and management. In this study, we conducted an accuracy and reliability analysis using a rank histogram, Brier score, and reliability diagram to verify LLWS...
Thu Feb 13, 2020 02:00
Atmosphere, Vol. 11, Pages 197: Dust Dry Deposition over Israel Atmosphere doi: 10.3390/atmos11020197 Authors: Kishcha Volpov Starobinets Alpert Nickovic Similar quasiperiodic year-to-year variations of dust dry deposition (DDD) with a two–three-year period were found over Israel and north-east Africa. This phenomenon of quasiperiodic interannual variations of DDD has not been discussed in previous publications. Moreover, similar seasonal variations of DDD...
Thu Feb 13, 2020 02:00
Bioengineering, Vol. 7, Pages 16: Early Detection of Atrial Fibrillation Based on ECG Signals Bioengineering doi: 10.3390/bioengineering7010016 Authors: Ahmed Zhu Atrial fibrillation, often called AF is considered to be the most common type of cardiac arrhythmia, which is a major healthcare challenge. Early detection of AF and the appropriate treatment is crucial if the symptoms seem to be consistent and persistent. This research work focused on the development of a heart monitoring...
Thu Feb 13, 2020 02:00
Biomedicines, Vol. 8, Pages 32: Basic Biology of Hypoxic Responses Mediated by the Transcription Factor HIFs and its Implication for Medicine Biomedicines doi: 10.3390/biomedicines8020032 Authors: Hirota Oxygen (O2) is essential for human life. Molecular oxygen is vital for the production of adenosine triphosphate (ATP) in human cells. O2 deficiency leads to a reduction in the energy levels that are required to maintain biological functions. O2 acts as the final acceptor of electrons...
Thu Feb 13, 2020 02:00
Biomolecules, Vol. 10, Pages 297: Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET Biomolecules doi: 10.3390/biom10020297 Authors: Oh Lee Kim Kwak Yoon Cho Liu Chae Shim Licochalcone D (LCD), a flavonoid isolated from a Chinese medicinal plant Glycyrrhiza inflata, has a variety of pharmacological activities. However, the anti-cancer effects of LCD on non-small cell lung cancer...
Thu Feb 13, 2020 02:00
Biomolecules, Vol. 10, Pages 298: Cyclic Dipeptides Mediating Quorum Sensing and Their Biological Effects in Hypsizygus Marmoreus Biomolecules doi: 10.3390/biom10020298 Authors: Sun Liu Weng Sun Li Li Zhu A novel quorum sensing (QS) system was discovered in Serratia odorifera, the symbiotic bacterium of Hypsizygus marmoreus. This system uses cyclo(Pro-Phe), cyclo(Pro-Tyr), cyclo(Pro-Val), cyclo(Pro-Leu), cyclo(Tyr-Leu), and cyclo(Tyr-Ile) as autoinducers. This...
Thu Feb 13, 2020 02:00
Biomolecules, Vol. 10, Pages 296: 2,4-Dichlorophenoxyacetic Thiosemicarbazides as a New Class of Compounds Against Stomach Cancer Potentially Intercalating with DNA Biomolecules doi: 10.3390/biom10020296 Authors: Pitucha Korga-Plewko Kozyra Iwan Kaczor hiosemicarbazide is a useful structural moiety that has the biological potential. Optimization of this structure can result in groundbreaking discovery of a new class of therapeutic agents. In the light of this, 1-(2,4-dichlorophenoxy)acetyl-4-(1-naphthyl)thiosemicarbazide...
Thu Feb 13, 2020 02:00
Biomolecules, Vol. 10, Pages 295: The Reliability of Iodine Concentration in Diaper-Retrieved Infant Urine Using Urine Collection Pads, and in Their Mothers’ Breastmilk Biomolecules doi: 10.3390/biom10020295 Authors: Bakken Oma Groufh-Jacobsen Solvik Mosand Langfjord Gjengedal Henjum Strand Mild to moderate iodine deficiency is common among women of childbearing age. Data on iodine status in infants are sparse, partly due to the challenges in collecting...
Thu Feb 13, 2020 02:00
Biomolecules, Vol. 10, Pages 294: Physico-Chemical Properties and Oxidative Stability of Fixed Oil from Plum Seeds (Prunus domestica Linn.) Biomolecules doi: 10.3390/biom10020294 Authors: Savic Savic Gajic Gajic Storage of a great amount of plum kernel waste becomes a challenge for food industry. In this work, the plum seed was used as a source of fixed oil that can be an ingredient of commercial products. Soxhlet extraction was carried out using the different solvents, such...
Thu Feb 13, 2020 02:00
Biomolecules, Vol. 10, Pages 293: Leptin-Responsive MiR-4443 Is a Small Regulatory RNA Independent of the Canonic MicroRNA Biogenesis Pathway Biomolecules doi: 10.3390/biom10020293 Authors: Meerson The human small RNA miR-4443 is functionally involved in several types of cancer and in the biology of the immune system, downstream of insulin and leptin signaling. Next generation sequencing evidence and structural prediction suggest that miR-4443 is not produced via the canonical Drosha–Exportin...
Thu Feb 13, 2020 02:00
Biomolecules, Vol. 10, Pages 292: Effect of Ultrasound Application on Protein Yield and Fate of Alkaloids during Lupin Alkaline Extraction Process Biomolecules doi: 10.3390/biom10020292 Authors: Luis Alberto Aguilar-Acosta Sergio O. Serna-Saldivar José Rodríguez-Rodríguez Anayansi Escalante-Aburto Cristina Chuck-Hernández The objective of this work is to elucidate the fate of quinolizidine alkaloids (QA) during the lupin protein extraction process assisted with ultrasound...
Thu Feb 13, 2020 02:00
Biomolecules, Vol. 10, Pages 291: Endothelial Dysfunction in Obesity-Induced Inflammation: Molecular Mechanisms and Clinical Implications Biomolecules doi: 10.3390/biom10020291 Authors: Ibrahim Kalle Kwaifa Hasnah Bahari Yoke Keong Yong Sabariah Md Noor Obesity is characterized by the excessive deposition of fat that may interfere with the normal metabolic process of the body. It is a chronic condition associated with various metabolic syndromes, whose prevalence is grossly...
Thu Feb 13, 2020 02:00
Biosensors, Vol. 10, Pages 12: Assessment of the Portable C-320 Electronic Nose for Discrimination of Nine Insectivorous Bat Species: Implications for Monitoring White-Nose Syndrome Biosensors doi: 10.3390/bios10020012 Authors: Doty Wilson Forse Risch The development of new C-320 electronic-nose (e-nose) methods for pre-symptomatic detection of White-Nose Syndrome (WNS) in bats has required efficacy studies of instrument capabilities to discriminate between major sources...
Thu Feb 13, 2020 02:00
Brain Sciences, Vol. 10, Pages 101: Saccular Aneurysm Models Featuring Growth and Rupture: A Systematic Review Brain Sciences doi: 10.3390/brainsci10020101 Authors: Marbacher Wanderer Strange Grüter Fandino Background. Most available large animal extracranial aneurysm models feature healthy non-degenerated aneurysm pouches with stable long-term follow-ups and extensive healing reactions after endovascular treatment. This review focuses on a small subgroup of extracranial...
Thu Feb 13, 2020 02:00
Brain Sciences, Vol. 10, Pages 100: Manual Dexterity is not Related to Media Viewing but is Related to Perceptual Bias in School-Age Children Brain Sciences doi: 10.3390/brainsci10020100 Authors: Nobusako Tsujimoto Sakai Shuto Furukawa Osumi Nakai Maeda Morioka Although the media can have both negative and positive effects on children’s cognitive and motor functions, its influence on their perceptual bias and manual dexterity is unclear. Thus,...
Thu Feb 13, 2020 02:00
Brain Sciences, Vol. 10, Pages 102: A Systematic Review of Human Neuroimaging Evidence of Memory-Related Functional Alterations Associated with Cannabis Use Complemented with Preclinical and Human Evidence of Memory Performance Alterations Brain Sciences doi: 10.3390/brainsci10020102 Authors: Grace Blest-Hopley Vincent Giampietro Sagnik Bhattacharyya Cannabis has been associated with deficits in memory performance. However, the neural correlates that may underpin impairments remain...
Thu Feb 13, 2020 02:00
Brain Sciences, Vol. 10, Pages 99: Exclusion Criteria Used in Early Behavioral Intervention Studies for Young Children with Autism Spectrum Disorder Brain Sciences doi: 10.3390/brainsci10020099 Authors: Yazdani Capuano Ghaziuddin Colombi This literature review evaluated early behavioral intervention studies of Autism Spectrum disorder (ASD) based on their participant exclusion criteria. The studies included were found through searching PsycINFO and PubMed databases, and...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 443: Nuclear Lamins and Emerin Are Differentially Expressed in Osteosarcoma Cells and Scale with Tumor Aggressiveness Cancers doi: 10.3390/cancers12020443 Authors: Urciuoli Petrini D’Oria Leopizzi Rocca Peruzzi The nuclear lamina is essential for the maintenance of nuclear shape and mechanics. Mutations in lamin genes have been identified in a heterogeneous spectrum of human diseases known as “laminopathies” associated...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 441: Repurposing Drugs for Acute Myeloid Leukemia: A Worthy Cause or a Futile Pursuit? Cancers doi: 10.3390/cancers12020441 Authors: Wojcicki Kadapakkam Frymoyer Lacayo Chae Sakamoto Acute myeloid leukemia (AML) is a clinically and genetically heterogenous malignancy of myeloid progenitor cells that affects patients of all ages. Despite decades of research and improvement in overall outcomes, standard therapy remains ineffective for certain...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 442: Pre-Analytical and Analytical Variables of Label-Independent Enrichment and Automated Detection of Circulating Tumor Cells in Cancer Patients Cancers doi: 10.3390/cancers12020442 Authors: Claudia Koch Simon A. Joosse Svenja Schneegans Okka J. W. Wilken Melanie Janning Desiree Loreth Volkmar Müller Katharina Prieske Malgorzata Banys-Paluchowski Ludwig J. Horst Sonja Loges Sven Peine Harriet Wikman Tobias M. Gorges Klaus...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 440: Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor Cancers doi: 10.3390/cancers12020440 Authors: Abdelilah Mekhloufi Andrea Kosta Helena Stabile Rosa Molfetta Alessandra Zingoni Alessandra Soriani Marco Cippitelli Rossella Paolini Angela Gismondi Maria Rosaria Ricciardi Maria Teresa Petrucci Laura Masuelli Giulio Caracciolo Sara Palchetti Angela Santoni...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 438: Targeting Melanoma Hypoxia with the Food-Grade Lactic Acid Bacterium Lactococcus Lactis Cancers doi: 10.3390/cancers12020438 Authors: Rodolfo Garza-Morales Beatriz E. Rendon Mohammad Tariq Malik Jeannete E. Garza-Cabrales Anne Aucouturier Luis G. Bermúdez-Humarán Kelly M. McMasters Lacey R. McNally Jorge G. Gomez-Gutierrez Melanoma is the most aggressive form of skin cancer. Hypoxia is a feature of the tumor microenvironment that reduces...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 437: FDA and EMA Approvals of New Breast Cancer Drugs—A Comparative Regulatory Analysis Cancers doi: 10.3390/cancers12020437 Authors: Chandra P. Leo Bettina Hentschel Thomas D. Szucs Cornelia Leo Breast cancer is the most common cancer in women worldwide and the solid tumor type for which the highest number of drugs have been approved to date. This study examines new drug approvals for breast cancer by the United States Food and Drug Administration (FDA)...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 436: Biphasic Mathematical Model of Cell–Drug Interaction That Separates Target-Specific and Off-Target Inhibition and Suggests Potent Targeted Drug Combinations for Multi-Driver Colorectal Cancer Cells Cancers doi: 10.3390/cancers12020436 Authors: Jinyan Shen Li Li Tao Yang Paul S. Cohen Gongqin Sun Quantifying the response of cancer cells to a drug, and understanding the mechanistic basis of the response, are the cornerstones for anti-cancer drug...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 439: Patient-Derived Xenograft Models in Urological Malignancies: Urothelial Cell Carcinoma and Renal Cell Carcinoma Cancers doi: 10.3390/cancers12020439 Authors: Andrew T. Tracey Katie S. Murray Jonathan A. Coleman Kwanghee Kim The engraftment of human tumor tissues into immunodeficient host mice to generate patient-derived xenograft (PDX) models has become increasingly utilized for many types of cancers. By capturing the unique genomic and molecular...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 435: Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro Cancers doi: 10.3390/cancers12020435 Authors: Marianne El Khoury Tony Haykal Mohammad H. Hodroj Sonia Abou Najem Rita Sarkis Robin I. Taleb Sandra Rizk Malva pseudolavatera Webb & Berthel. is a plant from the Malvaceae family that has long been included in the human diet due to its various curative effects. Many...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 431: PBX3 in Cancer Cancers doi: 10.3390/cancers12020431 Authors: Morgan Pandha PBX3 is a homeodomain-containing transcription factor of the pre-B cell leukemia (PBX) family, members of which have extensive roles in early development and some adult processes. A number of features distinguish PBX3 from other PBX proteins, including the ability to form specific and stable interactions with DNA in the absence of cofactors. PBX3 has frequently been reported as...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 433: The IL-1 Antagonist Anakinra Attenuates Glioblastoma Aggressiveness by Dampening Tumor-Associated Inflammation Cancers doi: 10.3390/cancers12020433 Authors: Hübner Effinger Wu Strauß Pogoda Kreth Kreth Background: The recombinant IL-1 receptor antagonist anakinra—currently approved for the treatment of autoinflammatory diseases—blocks IL-1β-mediated inflammatory signaling. As inflammation is a major driver...
Thu Feb 13, 2020 02:00
Cancers, Vol. 12, Pages 434: Clinical Pathways for Oncological Gastrectomy: Are They a Suitable Instrument for Process Standardization to Improve Process and Outcome Quality for Patients Undergoing Gastrectomy? A Retrospective Cohort Study Cancers doi: 10.3390/cancers12020434 Authors: Patrick Téoule Emrullah Birgin Christina Mertens Matthias Schwarzbach Stefan Post Nuh N. Rahbari Christoph Reißfelder Ulrich Ronellenfitsch (1) Background: Oncological gastrectomy requires...
Thu Feb 13, 2020 02:00
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