Abstract Purpose Forward progress in cancer treatment has resulted in fewer adverse consequences of cancer during and after treatment, offering employed cancer patients the possibility of continuing to work during treatment, returning to work after treatment, or implementing a combination of strategies to manage the cancer–work interface. Yet, much of the research on cancer and employment examines return to work as the primary outcome,...
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"Η Εκκλησία μας μπορεί επίσης να παίξει σημαντικό ρόλο στην ενημέρωση των ευπαθών ομάδων", σημειώνει ο καθηγητής Ηλίας Μόσιαλος.
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Energies, Vol. 13, Pages 1125: PD Plus Dynamic Pressure Feedback Control for a Direct Drive Stewart Manipulator Energies doi: 10.3390/en13051125 Authors: Chenyang Zhang In order to ensure good dynamic characteristics, servo valve is usually adopted as the drive part of Stewart manipulator which causes huge power consumption, while direct drive electro-hydraulic servo system has the advantages of energy saving, simple structure, convenient installation, and low failure rate. But...
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Applied Sciences, Vol. 10, Pages 1716: Five-Axis Freeform Surface Color Printing Technology Based on Offset Curve Path Planning Method Applied Sciences doi: 10.3390/app10051716 Authors: Hongyao Shen Bing Liu Senxin Liu Jianzhong Fu Great progress has been made in 2D color printing with inkjet technology, and mature related products have come out, but there still exists great developmental space in 3D color printing. Therefore, a new path planning method based on the...
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Insects, Vol. 11, Pages 161: First Report of Aleurocanthus spiniferus on Ailanthus altissima: Profiling of the Insect Microbiome and MicroRNAs Insects doi: 10.3390/insects11030161 Authors: Giovanni Bubici Maria Isabella Prigigallo Francesca Garganese Francesco Nugnes Maurice Jansen Francesco Porcelli We report the first occurrence of the orange spiny whitefly (Aleurocanthus spiniferus; OSW) on the tree of heaven (Ailanthus altissima) in Bari, Apulia region, Italy....
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JRFM, Vol. 13, Pages 45: A General Family of Autoregressive Conditional Duration Models Applied to High-Frequency Financial Data Journal of Risk and Financial Management doi: 10.3390/jrfm13030045 Authors: Danúbia R. Cunha Roberto Vila Helton Saulo Rodrigo N. Fernandez In this paper, we propose a general family of Birnbaum–Saunders autoregressive conditional duration (BS-ACD) models based on generalized Birnbaum–Saunders (GBS) distributions, denoted by GBS-ACD. We further...
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Mon Mar 02, 2020 22:13
Abstract Spinal cord plasticity is an important contributor of motor learning in humans, but its mechanisms are still poorly documented. In particular, it remains unclear whether short‐term spinal adaptations are general or task‐specific. As a marker of neural changes that are observable at spinal level, we measured the H‐reflex amplitude in the soleus muscle of 18 young healthy human adults before, immediately after (acquisition), and 24 h after (retention) the learning of a skilled task (i.e.,...
Mon Mar 02, 2020 22:13
Abstract Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a stressed‐induced cardiac channelopathy that has a high mortality in untreated patients. Our understanding has grown tremendously since CPVT was first described as a clinical syndrome in 1995: It is now established that the deadly arrhythmias are caused by unregulated “pathologic” calcium release from the sarcoplasmic reticulum (SR), the major calcium storage organelle in striated muscle. Important questions remain regarding...
Mon Mar 02, 2020 22:13
Key points Reciprocally connected GABAergic external globus pallidus (GPe) and glutamatergic subthalamic nucleus (STN) neurons form a key network within the basal ganglia. In Parkinson's disease and its models, abnormal rates and patterns of GPe‐STN network activity are linked to motor dysfunction. Using cell class‐specific optogenetic identification and inhibition during cortical slow‐wave activity and activation, we report that in dopamine‐depleted mice 1) D2 dopamine receptor expressing striatal...
Sat Feb 29, 2020 20:40
Fri Feb 28, 2020 19:58
Key points It is unclear whether the visual input that accompanies a perturbation of a standing person can affect whether a recovery step is taken. Visual motion speeds were manipulated during unexpected forward and backward shoulder pulls. Visual motion that appeared slower than actual body motion reduced the initial in‐place resistance to the perturbation. Due to the modulation of the in‐place response, less pull force was needed to trigger a step when visual velocity appeared slower than...
Fri Feb 28, 2020 19:58
By JESSICA DaMASSA, WTF HEALTH Sara Holoubek, Founder & CEO of Luminary Labs, a strategy and innovation consultancy — and the recognized “Queen” of identifying the undercurrents and sub-text of conversations at healthcare conferences — dishes about those undercurrents running just-below-the-surface at JP Morgan Healthcare 2020. Where’s the digital health market headed? Says Sara, “When you see too much bottle service at the parties…that’s when you should watch your back!” Filmed...
Mon Mar 02, 2020 21:43
Thomas Wilson Vince Kuraitis By THOMAS WILSON PhD, DrPH and VINCE KURAITIS JD, MBA A recent study in the New England Journal of Medicine reported on the results of a “hotspotting” program created by the Camden Coalition of Healthcare Providers (Camden Coalition). Hotspotting targets interventions at all or a subset of healthcare superutilizers – the 5% of patients that account for 50% of annual healthcare spending. The results of the study were disappointing. While utilization...
Mon Mar 02, 2020 16:00
By JESSICA DaMASSA, WTF HEALTH Savvy health tech startups can learn how the differing investment priorities of venture capital funds and strategic investors (those tied to large healthcare organizations like health plans, pharma companies, and health systems) can impact everything from their capital raise to their ability to gain new clients. Brent Stackhouse, Managing Director at Mount Sinai Ventures, talks about the nuances of investing as a strategic, trying to balance a health system’s...
Fri Feb 28, 2020 20:00
By CHRIS JAEGER MD, MBA The Primary Cares Initiative provides new value-based payment models aiming to enhance the delivery of primary care to promote efficiency and quality while decreasing healthcare costs. In the second part of this two-part series, we explore how eConsults directly support this new initiative across several key metrics. Introduction The Primary Cares Initiative aims to enhance the delivery of primary care through value-based payment models. In Part...
Fri Feb 28, 2020 16:00
Abstract We solve a functional equation connected to the algebraic characterization of generalized information functions. To prove the symmetry of the solution, we study a related system of functional equations, which involves two homographies. These transformations generate the modular group, and this fact plays a crucial role in solving the system. The method suggests a more general relation between conditional probabilities and arithmetic.
Mon Mar 02, 2020 02:00
Abstract Background Gender differences in organ involvement and clinical severity have been poorly described in hereditary hemorrhagic telangiectasia (HHT). The aim of this study was to describe differences in the severity of HHT manifestations according to gender. Methods Severity was measured according to Epistaxis Severity Score (ESS),...
Mon Mar 02, 2020 02:00
Abstract Background Re-fracture is the most serious complication in congenital pseudarthrosis of the tibia (CPT). There are reports that children with small cross-sectional areas in the sections of the pseudarthrosis are more prone to re-fracture. Presently, preventing complications is a challenge. Increasing the cross-sectional area in healed segments may reduce the incidence of re-fracture. ...
Mon Mar 02, 2020 02:00
Abstract Background Chondroblastoma (CB) is a rare locally aggressive bone tumor that commonly occurs in the epiphysis or apophysis of long bones. Although surgical treatment of CB carries potential risk for physeal or articular cartilage damage, risk factors for joint degeneration have not been well described. In addition, we have mainly used synthetic bone substitute (SBS) to fill the bone defect after intralesional curettage...
Mon Mar 02, 2020 02:00
Abstract Background A vascularized fibular osteomyocutaneous flap with severe vascular crisis often results in serious consequences. This study aims to examine the clinical effect of non-vascularized fibular graft on patients with severe vascular crisis after reconstruction of the defect jaw with vascularized fibular osteomyocutaneous flap. Materials and methods ...
Sat Feb 29, 2020 02:00
Abstract Background Primary intraosseous carcinoma (PIOC), NOS is an odontogenic carcinoma with unknown etiology. Its diagnosis may be used when central jaw carcinoma cannot be categorized as any other type of carcinoma. Further information on this extremely rare tumor is needed to improve our understanding and evaluate the classification of odontogenic carcinomas. ...
Sat Feb 29, 2020 02:00
About 25% of patients with chronic pain have features of borderline personality disorder, a finding that highlights the need for improved access to psychological care. Medscape Medical News
Mon Mar 02, 2020 21:37
The positive effects on psychological well-being of practicing transcendental meditation correlate with functional changes in the brain, according to a neuroimaging study. Medscape Medical News
Fri Feb 28, 2020 18:13
New research provides strong support that opioid agonists, methadone, or buprenorphine cut the risk of overdose death by 80%, yet many addiction programs don't offer them. Medscape Medical News
Fri Feb 28, 2020 17:47
Nature Reviews Neurology, Published online: 02 March 2020; doi:10.1038/s41582-020-0339-1Brain iron correlates with cognitive change in Parkinson disease
Mon Mar 02, 2020 02:00
Nature Reviews Neurology, Published online: 02 March 2020; doi:10.1038/s41582-020-0337-3High risk of epilepsy in children with Zika-related microcephaly
Mon Mar 02, 2020 02:00
Nature Reviews Neurology, Published online: 02 March 2020; doi:10.1038/s41582-020-0332-8A new study shows that interactions of the cellular prion protein with amyloid-β, tau and α-synuclein oligomers are important in mediating the toxicity of these proteins in Alzheimer disease and Parkinson disease. The findings suggest a shared pathway that could be a therapeutic target common to multiple neurodegenerative diseases.
Mon Mar 02, 2020 02:00
Nature Reviews Neurology, Published online: 02 March 2020; doi:10.1038/s41582-020-0338-2Trial casts doubt on tonic inhibition as a target in stroke treatment
Mon Mar 02, 2020 02:00
Abstract Background Different genetic characteristics according to tumor location result in variations in survival rates and treatment responses in advanced colorectal cancer (CRC). However, the effects of tumor location during early CRC are still unclear. Methods Patients with T1 CRC treated between 2003 and 2019 were enrolled from a prospectively...
Mon Mar 02, 2020 02:00
Abstract Background The optimal dose of each drug used in the docetaxel, oxaliplatin, and S-1 (DOS) chemotherapy remains to be clarified for the Japanese population. The purpose of this study was to determine a recommended dose for a combination neoadjuvant DOS chemotherapy for Japanese patients with locally advanced adenocarcinoma of the esophagogastric junction (AEG). ...
Mon Mar 02, 2020 02:00
by Fergal M. Waldron, Graham N. Stone, Darren J. Obbard
Mon Mar 02, 2020 22:00
by Richard Howey, So-Youn Shin, Caroline Relton, George Davey Smith, Heather J. Cordell Mendelian randomization (MR) implemented through instrumental variables analysis is an increasingly popular causal inference tool used in genetic epidemiology. But it can have limitations for evaluating simultaneous causal relationships in complex data sets that include, for example, multiple genetic predictors and multiple potential risk factors associated with the same genetic variant. Here we use real...
Mon Mar 02, 2020 22:00
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