Related ArticlesEffectiveness of Adjunctive Analgesics in Head and Neck Cancer Patients Receiving Curative (Chemo-) Radiotherapy: A Systematic Review. Pain Med. 2020 Mar 27;: Authors: Lefebvre T, Tack L, Lycke M, Duprez F, Goethals L, Rottey S, Cool L, Van Eygen K, Stubbs B, Schofield P, Pottel H, Boterberg T, Debruyne P Abstract OBJECTIVE: Our aim was to give an overview of the effectiveness of adjunctive analgesics in head and neck cancer (HNC)...
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Related ArticlesDetecting Recurrence Following Lobectomy for Thyroid Cancer: Role of Thyroglobulin and Thyroglobulin Antibodies. J Clin Endocrinol Metab. 2020 Mar 27;: Authors: Ritter A, Mizrachi A, Bachar G, Vainer I, Shimon I, Hirsch D, Diker-Cohen T, Duskin-Bitan H, Robenshtok E Abstract BACKGROUND: The use of thyroglobuin (Tg) and thyroglobulin antibodies (TgAb) for detecting disease recurrence is well validated following total-thyroidectomy...
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Related ArticlesGeographical and Racial Disparities in Head and Neck Cancer Diagnosis in South-Eastern United States: Using Real-World Electronic Medical Records Data. Health Equity. 2020;4(1):43-51 Authors: Mukherjee A, Idigo AJ, Ye Y, Wiener HW, Paluri R, Nabell LM, Shrestha S Abstract Background: Rurality, race, and age at diagnosis are important predictors in head and neck cancer (HNC) prognosis. However, literature on the associations of rurality...
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Related ArticlesRhabdomyosarcoma: Nose Presenting As Second Primary with Carcinoma Tongue. Iran J Otorhinolaryngol. 2020 Mar;32(109):121-125 Authors: Kwatra D, Sagar P, Shukla S Abstract Introduction: Presence of two primary malignancies is rare and occurs in 3-5% of the cancer patients. As per our extensive internet research, this is the only reported case of a synchronous sino-nasal embryonal rhabdomyosarcoma with squamous cell carcinoma-tongue....
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Related ArticlesFibrin Glue in Postlaryngectomy Fistula-A Case Report. Iran J Otorhinolaryngol. 2020 Mar;32(109):113-119 Authors: Vossoughinia H, Zarringhalam MA, Hamidi Alamdari D, Mehrdad Zinkanlou A Abstract Introduction: One of the most common complications following total laryngectomy is pharyngocutaneous fistula (PCF). Various methods have been proposed to treat this disorder in recent studies, including a range of simple and conservative treatments...
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Related ArticlesGiant Thyroid Fibrosarcoma- A Case Report. Iran J Otorhinolaryngol. 2020 Mar;32(109):109-112 Authors: Tucciarone M, Heredia-Llinas C, Lowy-Benoliel A, Souviron-Encabo R, Martínez-Guirado T, Álvarez-Morujo RG Abstract Introduction: Thyroid gland fibrosarcomas are extremely rare tumors, and only very few cases have been described in the literature. There are no set recommendations along with follow-ups regarding the treatment of these...
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Related ArticlesPrevalence of Hearing Loss among School-Age Children in the North of Iran. Iran J Otorhinolaryngol. 2020 Mar;32(109):85-92 Authors: Jalali MM, Nezamdoust F, Ramezani H, Pastadast M Abstract Introduction: The present study aimed to investigate the audiological profiles of elementary school-age children in Rasht, Iran, and estimate the prevalence of hearing impairments in this population. Materials and Methods: In this cross-sectional...
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Related ArticlesValidity and Reliability of Persian Smell Identification Test. Iran J Otorhinolaryngol. 2020 Mar;32(109):65-71 Authors: Kamrava SK, Jalessi M, Ghalehbaghi S, Amini E, Alizadeh R, Rafiei F, Moosa S, Farhadi M Abstract Introduction: Smell Identification Tests (SIT) are routinely utilized for the clinical evaluation of olfactory function. Since Iran consists of various ethnic subgroups, the reliability and validity of this test as a...
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Related ArticlesApatinib Inhibits Cell Proliferation and Induces Autophagy in Human Papillary Thyroid Carcinoma via the PI3K/Akt/mTOR Signaling Pathway. Front Oncol. 2020;10:217 Authors: Meng X, Wang H, Zhao J, Hu L, Zhi J, Wei S, Ruan X, Hou X, Li D, Zhang J, Yang W, Qian B, Wu Y, Zhang Y, Meng Z, Guan L, Zhang H, Zheng X, Gao M Abstract Background: Patients with metastatic radioiodine-refractory papillary thyroid carcinoma (PTC) have limited treatment...
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Related ArticlesTranscription levels and prognostic significance of the NFI family members in human cancers. PeerJ. 2020;8:e8816 Authors: Li Y, Sun C, Tan Y, Li L, Zhang H, Liang Y, Zeng J, Zou H Abstract Background: The nuclear factor I (NFI) is a family of transcription factors consisting of four distinct but closely related genes, NFIA, NFIB, NFIC and NFIX, which are important in the development of various tissues and organs in mammals. Recent...
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Related ArticlesIntegrated analysis of transcriptome profiling predicts potential lncRNA and circRNA targets in human nasopharyngeal carcinoma. Oncol Lett. 2020 Apr;19(4):3123-3136 Authors: Zhou DN, Ye CS, Yang QQ, Deng YF Abstract Non-coding RNAs (ncRNAs) regulate numerous genes and influence the progression of various human diseases, including cancer. The role of regulatory ncRNAs implicated in nasopharyngeal carcinoma (NPC), as well as their target...
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Related ArticlesRapamycin inhibits proliferation and apoptosis of retinoblastoma cells through PI3K/AKT signaling pathway. Oncol Lett. 2020 Apr;19(4):2950-2956 Authors: Yao J, Xu M, Liu Z Abstract Effects of Rapamycin on the proliferation and apoptosis of retinoblastoma cells through the phosphatidylinositol 3-hydroxy kinase (PI3K)/protein kinase B (AKT) signaling pathway were studied. The retinoblastoma Y79 cells were selected and divided into negative...
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Related ArticlesMicroRNA-212 suppresses cell proliferation in nasopharyngeal carcinoma by targeting ELF3. Oncol Lett. 2020 Apr;19(4):2902-2908 Authors: Kang Y, Cui Y, Tan M Abstract Nasopharyngeal carcinoma (NPC) is an epithelial malignancy of the head and neck that is prevalent in China. The present study investigated the molecular mechanisms of microRNA-212 (miR-212) and E74-like factor 3 (ELF3) in NPC cell lines and tissues. Using reverse transcription-quantitative...
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Related ArticlesDe novo metastatic breast cancer: Subgroup analysis of molecular subtypes and prognosis. Oncol Lett. 2020 Apr;19(4):2884-2894 Authors: Zhang L, Li Z, Zhang J, Wu Y, Zhu Y, Tong Z Abstract The purpose of the present study was to analyze the clinical and pathological characteristics, treatment, and prognosis of de novo metastatic breast cancer (DnMBC). Information regarding 1,890 patients treated for advanced breast cancer at the Tianjin...
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Related ArticleslncRNA SNHG7 promotes tumorigenesis of nasopharyngeal carcinoma via epithelial-to-mesenchymal transition. Oncol Lett. 2020 Apr;19(4):2721-2726 Authors: Xu W, Sun X, Zang C, Jiang Y Abstract Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors. Studies have indicated that long noncoding RNAs (lncRNAs) function as important regulators in progression of tumorigenesis. In this study, lncRNA small nucleolar RNA host...
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Related ArticlesPodoplanin is an efficient predictor of neck lymph node metastasis in tongue squamous cell carcinoma with low tumor budding grade. Oncol Lett. 2020 Apr;19(4):2602-2608 Authors: Hamada M, Ebihara Y, Nagata K, Yano M, Kogashiwa Y, Nakahira M, Sugasawa M, Nagatsuka H, Yasuda M Abstract The current study investigated the efficacy of podoplanin expression in tumor budding cells as a predictor of neck lymph node metastasis (NLM) in patients...
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Related ArticlesPrognosis in young women less than 40 years of age with brain metastasis from breast cancer. Curr Oncol. 2020 Feb;27(1):39-45 Authors: Mustillo A, Ayoub JP, Charpentier D, Yelle L, Florescu M Abstract Background: Brain metastasis from breast cancer (bca) in young women is doubly devastating because both quality of life and life expectancy are significantly reduced. With new radiation technology and drugs that have emerged, survival...
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Related ArticlesImage-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma. PLoS One. 2020;15(3):e0230492 Authors: Massey SC, White H, Whitmire P, Doyle T, Johnston SK, Singleton KW, Jackson PR, Hawkins-Daarud A, Bendok BR, Porter AB, Vora S, Sarkaria JN, Hu LS, Mrugala MM, Swanson KR Abstract BACKGROUND: Temozolomide (TMZ) has been the standard-of-care chemotherapy for glioblastoma (GBM) patients for more...
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Related ArticlesVasculoprotective Effects of Vildagliptin. Focus on Atherogenesis. Int J Mol Sci. 2020 Mar 25;21(7): Authors: Wiciński M, Górski K, Wódkiewicz E, Walczak M, Nowaczewska M, Malinowski B Abstract Vildagliptin is a representative of Dipeptidyl Peptidase-4 (DPP-4) inhibitors, antihyperglycemic drugs, approved for use as monotherapy and combination therapy in type 2 diabetes mellitus. By inhibiting enzymatic decomposition, DPP-4 inhibitors...
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Related ArticlesAlpha-Lipoic Acid Ameliorates Radiation-Induced Salivary Gland Injury by Preserving Parasympathetic Innervation in Rats. Int J Mol Sci. 2020 Mar 25;21(7): Authors: Kim JH, Jeong BK, Jang SJ, Yun JW, Jung MH, Kang KM, Kim TG, Woo SH Abstract Radiation therapy is a standard treatment for patients with head and neck cancer. However, radiation exposure to the head and neck induces salivary gland (SG) dysfunction. Alpha lipoic acid (ALA)...
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Related ArticlesRole of concurrent chemoradiation on locally advanced unresectable adenoid cystic carcinoma. Korean J Intern Med. 2020 Mar 30;: Authors: Ha H, Keam B, Ock CY, Kim TM, Kim JH, Chung EJ, Kwon SK, Ahn SH, Wu HG, Sung MW, Heo DS Abstract Background/Aims: Adenoid cystic carcinoma (ACC) is a rare salivary gland tumor characterized by indolence, with a high rate of local recurrence and distant metastasis. This study aimed to investigate...
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Related ArticlesAirway Anatomy of an Adult with Hurler's Syndrome. Anesthesiology. 2020 Mar 24;: Authors: Dalesio NM, Ifaturoti OA, Tomeldan CM, Tran TP PMID: 32217872 [PubMed - as supplied by publisher]
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Related ArticlesA new oncolytic V accinia virus augments antitumor immune responses to prevent tumor recurrence and metastasis after surgery. J Immunother Cancer. 2020 Mar;8(1): Authors: Ahmed J, Chard LS, Yuan M, Wang J, Howells A, Li Y, Li H, Zhang Z, Lu S, Gao D, Wang P, Chu Y, Al Yaghchi C, Schwartz J, Alusi G, Lemoine N, Wang Y Abstract BACKGROUND: Local recurrence and remote metastasis are major challenges to overcome in order to improve the...
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Related ArticlesCD244 represents a new therapeutic target in head and neck squamous cell carcinoma. J Immunother Cancer. 2020 Mar;8(1): Authors: Agresta L, Lehn M, Lampe K, Cantrell R, Hennies C, Szabo S, Wise-Draper T, Conforti L, Hoebe K, Janssen EM Abstract BACKGROUND: Developing novel strategies to overcome the immunosuppressive tumor microenvironment is a critically important area of cancer therapy research. Here, we assess the therapeutic potential...
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Related ArticlesEstablishing guidelines to harmonize tumor mutational burden (TMB): in silico assessment of variation in TMB quantification across diagnostic platforms: phase I of the Friends of Cancer Research TMB Harmonization Project. J Immunother Cancer. 2020 Mar;8(1): Authors: Merino DM, McShane LM, Fabrizio D, Funari V, Chen SJ, White JR, Wenz P, Baden J, Barrett JC, Chaudhary R, Chen L, Chen WS, Cheng JH, Cyanam D, Dickey JS, Gupta V, Hellmann M, Helman E, Li...
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Related ArticlesUnilateral bloodstained nasal discharge. BMJ. 2020 Mar 26;368:m9 Authors: Huang Z, Huang Q PMID: 32217604 [PubMed - as supplied by publisher]
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Related ArticlesDouble free flaps in oral cavity and oropharynx reconstruction: Systematic review, indications and limits. Oral Oncol. 2020 Mar 24;104:104637 Authors: Mannelli G, Gazzini L, Comini LV, Parrinello G, Nocini R, Marchioni D, Molteni G Abstract The simultaneous use of two different free flaps, harvested from distinct donor sites, has demonstrated a reasonable degree of safety and success rates in head and neck composite defects reconstruction....
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Related ArticlesA novel kernel Wasserstein distance on Gaussian measures: An application of identifying dental artifacts in head and neck computed tomography. Comput Biol Med. 2020 Mar 26;120:103731 Authors: Oh JH, Pouryahya M, Iyer A, Apte AP, Deasy JO, Tannenbaum A Abstract The Wasserstein distance is a powerful metric based on the theory of optimal mass transport. It gives a natural measure of the distance between two distributions with a wide...
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Related ArticlesDevelopment of a new fully three-dimensional methodology for tumours delineation in functional images. Comput Biol Med. 2020 Mar 16;120:103701 Authors: Comelli A, Bignardi S, Stefano A, Russo G, Sabini MG, Ippolito M, Yezzi A Abstract Delineation of tumours in Positron Emission Tomography (PET) plays a crucial role in accurate diagnosis and radiotherapy treatment planning. In this context, it is of outmost importance to devise efficient...
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Related ArticlesSolitary fibrous tumors of the head and neck region revisited: A single-institution study of 20 cases and review of the literature. Hum Pathol. 2020 Mar 23;: Authors: Baněčková M, Martínek P, Skálová A, Mezencev R, Hadravský L, Michal M, Švajdler M Abstract A solitary fibrous tumor (SFT) is a rare, NAB2-STAT6 fusion gene-associated mesenchymal neoplasm. It most commonly arises in the pleural site, but it can occur at many other sites,...
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Related ArticlesAssessing Patients' Perceptions of Cancer Care Coordination in a Community-Based Setting. JCO Oncol Pract. 2020 Mar 27;:JOP1900509 Authors: Okado I, Cassel K, Pagano I, Holcombe RF Abstract PURPOSE: Effective care coordination (CC) is a hallmark of a high-quality cancer care. However, efforts to improve cancer care delivery are limited by the lack of a clinically useful tool to assess CC. In this study, we examined patients' perceptions...
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Related ArticlesAcquired secondary RAS mutation in BRAFV600E mutated thyroid cancer patients treated with BRAF inhibitors. Thyroid. 2020 Mar 26;: Authors: Cabanillas M, Dadu R, Iyer PC, Wanland KB, Busaidy N, Ying AK, Gule-Monroe M, Wang JR, Zafereo M, Hofmann MC Abstract The BRAFV600E mutation is the most common driver mutation in papillary thyroid cancer (PTC) and anaplastic thyroid cancer (ATC). This mutation is considered actionable and, for...
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Related ArticlesVestibular-evoked myogenic potentials in patients with severe obstructive sleep apnea. J Int Med Res. 2020 Mar;48(3):300060520909717 Authors: Gao T, Zhang Q, Hou J, Zhu K, Sun B, Chen J, Xia C, Ren X, Cheng Y, Wang Z PMID: 32216492 [PubMed - as supplied by publisher]
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Related Articles[Rho/ROCK signaling pathway and anti-cryodamage ability of human sperm]. Zhonghua Nan Ke Xue. 2019 Apr;25(5):322-328 Authors: Tian J, Zhang SH, Ma K, Zhao BY, Yan B, Pei CB, Zhou Y, Wang HH, Wang HY, Ma LH, Zhang XZ Abstract Objective: To investigate the influence of the Rho/ROCK signaling pathway on the anti-cryodamage ability of human sperm and provide some theoretical evidence for the development of high-efficiency semen cryoprotectants....
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Related ArticlesReversible obstruction of the olfactory cleft: impact on olfactory perception and nasal patency. Int Forum Allergy Rhinol. 2020 Mar 26;: Authors: Besser G, Liu DT, Renner B, Hummel T, Mueller CA Abstract BACKGROUND: Temporary disruption of sensory input can be studied relatively easily for vision or hearing by covering the eyes or ears. In contrast, closing the nostrils affects not only the sense of smell, but also the ability to...
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Related ArticlesCost and operative time estimation itemized by component procedures of endoscopic sinus surgery. Int Forum Allergy Rhinol. 2020 Mar 26;: Authors: Thomas AJ, McCoul ED, Meier JD, Newberry CI, Smith TL, Alt JA Abstract BACKGROUND: Endoscopic sinus surgery (ESS) is a variable combination of individual procedures. Cost estimates for ESS as a single entity have wide variation, likely influenced by variation in procedures performed. We...
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Related ArticlesIn Response to Regarding Surgical Impact of a Dedicated Endocrine Surgeon on an Academic Otolaryngology Department. Laryngoscope. 2020 Mar 26;: Authors: Iwata AJ, Chang SS, Ghanem TA, Singer MC PMID: 32216099 [PubMed - as supplied by publisher]
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Related ArticlesLNCAROD is stabilized by m6A methylation and promotes cancer progression via forming a ternary complex with HSPA1A and YBX1 in head and neck squamous cell carcinoma. Mol Oncol. 2020 Mar 25;: Authors: Ban Y, Tan P, Cai J, Li J, Hu M, Zhou Y, Mei Y, Tan Y, Li X, Zeng Z, Xiong W, Li G, Li X, Yi M, Xiang B Abstract Head and neck squamous cell carcinoma (HNSCC) constitute approximately 4% of all cancers worldwide. In this study, we analyzed...
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Related ArticlesOncogenic pseudogene DUXAP10 knockdown suppresses proliferation and invasion and induces apoptosis of papillary thyroid carcinoma cells by inhibition of Akt/mTOR pathway. Clin Exp Pharmacol Physiol. 2020 Mar 25;: Authors: Li J, Jiang L, Liu Z, Li Y, Xu Y, Liu H Abstract Pseudogenes, another novel group of non-coding segments without protein-coding capacity, is closely associated with tumorigenesis and cancer progression. Double homeobox...
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