JCDD, Vol. 7, Pages 10: Timing of Heparin Administration Modulates Arterial Occlusive Thrombotic Response in Rats Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7010010 Authors: Matrai Kastetter Cooley Background: The timing for initiation of effective antithrombotic therapy relative to the onset of arterial thrombosis may influence outcomes. This report investigates the hypothesis that early administration of heparin anticoagulation relative to the onset...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 831: Right Ventricular Dysfunction Staging System for Mortality Risk Stratification in Heart Failure With Preserved Ejection Fraction Journal of Clinical Medicine doi: 10.3390/jcm9030831 Authors: Santas De la Espriella Chorro Palau Miñana Heredia Amiguet Merenciano Sanchis Lupón Bayés-Genís Núñez Right ventricular dysfunction (RVD) parameters are increasingly important features in heart failure with preserved ejection fraction...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 829: The Influence of Vaginal Native Tissues Pelvic Floor Reconstructive Surgery in Patients with Symptomatic Pelvic Organ Prolapse on Preexisting Storage Lower Urinary Tract Symptoms (LUTS) Journal of Clinical Medicine doi: 10.3390/jcm9030829 Authors: Rechberger Skorupska Rechberger Wojtaś Miotła Kulik-Rechberger Wróbel The aim of this study was to assess the effectiveness of vaginal native tissue repair (VNTR) on preexisting Lower Urinary...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 830: Intraoperative Autofluorescence and Indocyanine Green Angiography for the Detection and Preservation of Parathyroid Glands Journal of Clinical Medicine doi: 10.3390/jcm9030830 Authors: Demarchi Karenovics Bédat Triponez Fluorescence imaging is a well-known method for both the in vivo and in vitro identification of specific cells or tissues. This imaging tool is gaining importance in the intraoperative detection and preservation of parathyroid glands...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 828: Network Mapping of Connectivity Alterations in Disorder of Consciousness: Towards Targeted Neuromodulation Journal of Clinical Medicine doi: 10.3390/jcm9030828 Authors: Lucia Mencarelli Maria Chiara Biagi Ricardo Salvador Sara Romanella Giulio Ruffini Simone Rossi Emiliano Santarnecchi Disorder of consciousness (DoC) refers to a group of clinical conditions that may emerge after brain injury, characterized by a varying decrease in the level of...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 827: Improved Isolation and Culture of Urine-Derived Stem Cells (USCs) and Enhanced Production of Immune Cells from the USC-Derived Induced Pluripotent Stem Cells Journal of Clinical Medicine doi: 10.3390/jcm9030827 Authors: Kim Gil Dayem Choi Kang Yang Cho Jeong Kim Seok Kwak Saha Kim Cho The availability of autologous adult stem cells is one of the essential prerequisites for human stem cell therapy. Urine-derived...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 824: Endothelin Receptor Antagonists: Status Quo and Future Perspectives for Targeted Therapy Journal of Clinical Medicine doi: 10.3390/jcm9030824 Authors: Frederik C. Enevoldsen Jayashree Sahana Markus Wehland Daniela Grimm Manfred Infanger Marcus Krüger The endothelin axis, recognized for its vasoconstrictive action, plays a central role in the pathology of pulmonary arterial hypertension (PAH). Treatment with approved endothelin receptor antagonists...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 825: Effect of a Preoperative Proton Pump Inhibitor and Gastroesophageal Reflux Disease on Postoperative Nausea and Vomiting Journal of Clinical Medicine doi: 10.3390/jcm9030825 Authors: Young Suk Kwon Jun Woo Choi Ho Seok Lee Jong Ho Kim Youngmi Kim Jae Jun Lee Postoperative nausea and vomiting (PONV) are common complications after anesthesia, but no study has considered the effects of a proton pump inhibitor (PPI) and gastroesophageal reflux disease...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 826: Vertebral Bone Marrow and Endplate Assessment on MR Imaging for the Differentiation of Modic Type 1 Endplate Changes and Infectious Spondylodiscitis Journal of Clinical Medicine doi: 10.3390/jcm9030826 Authors: Schwarz-Nemec Friedrich Stihsen Schwarz Trattnig Weber Grohs Nemec On magnetic resonance (MR) imaging, Modic type 1 (MT1) endplate changes and infectious spondylodiscitis share similar findings. Therefore, this study investigated...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 823: Updating the Definition of the Alcohol Hangover Journal of Clinical Medicine doi: 10.3390/jcm9030823 Authors: Joris C. Verster Andrew Scholey Aurora J.A.E. van de Loo Sarah Benson Ann-Kathrin Stock In 2016, the Alcohol Hangover Research Group defined the alcohol hangover as “the combination of mental and physical symptoms experienced the day after a single episode of heavy drinking, starting when blood alcohol concentration (BAC) approaches...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 820: Ponatinib Induces Vascular Toxicity through the Notch-1 Signaling Pathway Journal of Clinical Medicine doi: 10.3390/jcm9030820 Authors: Rosalinda Madonna Damiana Pieragostino Maria Concetta Cufaro Vanessa Doria Piero Del Boccio Martino Deidda Sante Donato Pierdomenico Christian Cadeddu Dessalvi Raffaele De Caterina Giuseppe Mercuro Ponatinib, a third-generation tyrosine kinase inhibitor (TKI), is the only approved TKI that is effective...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 821: Added-Value of Endometrial Biopsy in the Diagnostic and Therapeutic Strategy for Pelvic Actinomycosis Journal of Clinical Medicine doi: 10.3390/jcm9030821 Authors: Julie Carrara Blandine Hervy Yohann Dabi Claire Illac Bassam Haddad Dounia Skalli Gregoire Miailhe Fabien Vidal Cyril Touboul Charlotte Vaysse The particularity of pelvic actinomycosis lies in the difficulty of establishing the diagnosis prior to treatment. The objective of...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 822: Health in Preconception, Pregnancy and Postpartum Global Alliance: International Network Pregnancy Priorities for the Prevention of Maternal Obesity and Related Pregnancy and Long-Term Complications Journal of Clinical Medicine doi: 10.3390/jcm9030822 Authors: Briony Hill Helen Skouteris Jacqueline A. Boyle Cate Bailey Ruth Walker Shakila Thangaratinam Hildrun Sundseth Judith Stephenson Eric Steegers Leanne M. Redman Cynthia Montanaro Siew...
Wed Mar 18, 2020 02:00
JCM, Vol. 9, Pages 819: Real-Life Patterns of Exacerbations While on Inhaled Corticosteroids and Long-Acting Beta Agonists for Asthma over 15 Years Journal of Clinical Medicine doi: 10.3390/jcm9030819 Authors: Michael J. McGeachie Alberta L. Wang Sharon M. Lutz Joanne E. Sordillo Scott T. Weiss Kelan G. Tantisira Carlos Iribarren Meng X. Lu Ann Chen Wu Asthma affects more than 300 million people in the world, costs over $80 billion annually in the United States,...
Wed Mar 18, 2020 02:00
Life, Vol. 10, Pages 27: Extensive Diversity and Disparity of the Early Miocene Platanistoids (Cetacea, Odontoceti) in the Southeastern Pacific (Chilcatay Formation, Peru) Life doi: 10.3390/life10030027 Authors: Bianucci de Muizon Urbina Lambert Several aspects of the fascinating evolutionary history of toothed and baleen whales (Cetacea) are still to be clarified due to the fragmentation and discontinuity (in space and time) of the fossil record. Here we open a window on...
Wed Mar 18, 2020 02:00
Life, Vol. 10, Pages 26: Circumnutation and Growth of Inflorescence Stems of Arabidopsis thaliana in Response to Microgravity under Different Photoperiod Conditions Life doi: 10.3390/life10030026 Authors: Yuanyuan Wu Junyan Xie Lihua Wang Huiqiong Zheng Circumnutation is a periodic growth movement, which is an important physiological mechanism of plants to adapt to their growth environments. Gravity and photoperiod are two key environmental factors in regulating the circumnutation...
Wed Mar 18, 2020 02:00
Medicina, Vol. 56, Pages 135: Anatomical Morphology Analysis of Internal Jugular Veins and Factors Affecting Internal Jugular Vein Size Medicina doi: 10.3390/medicina56030135 Authors: Jeon Choi Lee Lee Background and objectives: There is a paucity of research on the shape of internal jugular vein (IJV) and their association with an individual’s morphology and various chronic diseases. Therefore, this study aimed to analyze the anatomy of the IJV across various...
Wed Mar 18, 2020 02:00
Medicina, Vol. 56, Pages 134: Primary Prevention of Cardiovascular Risk in Lithuania–Results from EUROASPIRE V Survey Medicina doi: 10.3390/medicina56030134 Authors: Urbonas Vencevičienė Valius Krivickienė Petrauskas Lazarenkienė Karpavičienė Briedė Žučenkienė Vencevičius Background and Objectives: Cardiovascular disease (CVD) prevention guidelines define targets for lifestyle and risk factors for patients at high risk of developing CVD. We assessed...
Wed Mar 18, 2020 02:00
Medicina, Vol. 56, Pages 133: Evaluation of the Direct Economic Cost per Eradication Treatment Regimen against Helicobacter pylori Infection in Greece: Do National Health Policy-Makers Need to Care? Medicina doi: 10.3390/medicina56030133 Authors: Christos Liatsos Apostolis Papaefthymiou Nikolaos Kyriakos Marios Giakoumis Jannis Kountouras Michail Galanopoulos Periklis Apostolopoulos Sotirios D. Georgopoulos Christos Mavrogiannis Aristomenis K. Exadaktylos David...
Wed Mar 18, 2020 02:00
Medicina, Vol. 56, Pages 136: Investigation of the Effect of Written and Visual Information on Anxiety Measured Before Magnetic Resonance Imaging: Which Method is Most Effective? Medicina doi: 10.3390/medicina56030136 Authors: Burkay Yakar Edibe Pirinçci Background and objective: Magnetic resonance imaging (MRI) causes severe anxiety in some patients. Anxiety during MRI leads to prolongation of the procedure and deterioration of image quality, resulting in loss of labor and cost increase....
Wed Mar 18, 2020 02:00
Medicina, Vol. 56, Pages 132: Fracture Resistance of New Metal-Free Materials Used for CAD-CAM Fabrication of Partial Posterior Restorations Medicina doi: 10.3390/medicina56030132 Authors: Georgina García-Engra Lucia Fernandez-Estevan Javier Casas-Terrón Antonio Fons-Font Pablo Castelo-Baz Rubén Agustín-Panadero Juan Luis Román-Rodriguez Background and Objectives: To evaluate in vitro the fracture resistance and fracture type of computer-aided design and computer-aided...
Wed Mar 18, 2020 02:00
Medicines, Vol. 7, Pages 14: The Combined Use of Stem Cells and Platelet Lysate Plasma for the Treatment of Erectile Dysfunction: A Pilot Study–6 Months Results Medicines doi: 10.3390/medicines7030014 Authors: Vassilis Protogerou Sara El Beshari Efstathios Michalopoulos Panagiotis Mallis Dimosthenis Chrysikos Alexandros A. Samolis Catherine Stavropoulos-Giokas Theodoros Troupis Background: The current treatment of Erectile Dysfunction (ED) is mainly based on the...
Wed Mar 18, 2020 02:00
Membranes, Vol. 10, Pages 48: Morphology of Thin Film Composite Membranes Explored by Small-Angle Neutron Scattering and Positron-Annihilation Lifetime Spectroscopy Membranes doi: 10.3390/membranes10030048 Authors: Pipich Dickmann Frielinghaus Kasher Hugenschmidt Petry Oren Schwahn The morphology of thin film composite (TFC) membranes used in reverse osmosis (RO) and nanofiltration (NF) water treatment was explored with small-angle neutron scattering (SANS)...
Wed Mar 18, 2020 02:00
Membranes, Vol. 10, Pages 47: Removal of Dye from a Leather Tanning Factory by Flat-Sheet Blend Ultrafiltration (UF) Membrane Membranes doi: 10.3390/membranes10030047 Authors: Maryam Y. Ghadhban Hasan Shaker Majdi Khalid T. Rashid Qusay F. Alsalhy D. Shanthana Lakshmi Issam K. Salih Alberto Figoli In this work, a flat-sheet blend membrane was fabricated by a traditional phase inversion method, using the polymer blends poly phenyl sulfone (PPSU) and polyether sulfone...
Wed Mar 18, 2020 02:00
Metabolites, Vol. 10, Pages 113: 16HBE Cell Lipid Mediator Responses to Mono and Co-Infections with Respiratory Pathogens Metabolites doi: 10.3390/metabo10030113 Authors: Schultz Surabhi Stelling Rothe Group Methling Hammerschmidt Siemens Lalk Respiratory tract infections are a global health problem. The main causative agents of these infections are influenza A virus (IAV), Staphylococcus aureus (S. aureus), and Streptococcus pneumoniae (S. pneumoniae)....
Wed Mar 18, 2020 02:00
Microorganisms, Vol. 8, Pages 430: Optimised Production and Extraction of Astaxanthin from the Yeast Xanthophyllomyces dendrorhous Microorganisms doi: 10.3390/microorganisms8030430 Authors: Zuharlida Tuan Harith Micael de Andrade Lima Dimitris Charalampopoulos Afroditi Chatzifragkou Currently, astaxanthin demand is fulfilled by chemical synthesis using petroleum-based feedstocks. As such, alternative pathways of natural astaxanthin production attracts much research interest....
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Microorganisms, Vol. 8, Pages 428: Yeasts and Bacterial Consortia from Kefir Grains Are Effective Biocontrol Agents of Postharvest Diseases of Fruits Microorganisms doi: 10.3390/microorganisms8030428 Authors: V. Yeka Zhimo Antonio Biasi Ajay Kumar Oleg Feygenberg Shoshana Salim Silvana Vero Michael Wisniewski Samir Droby Fungal pathogens in fruits and vegetables cause significant losses during handling, transportation, and storage. Biological control with microbial...
Wed Mar 18, 2020 02:00
Microorganisms, Vol. 8, Pages 429: Plasmid-Mediated Colistin Resistance (mcr-1) in Escherichia coli from Non-Imported Fresh Vegetables for Human Consumption in Portugal Microorganisms doi: 10.3390/microorganisms8030429 Authors: Vera Manageiro Daniela Jones-Dias Eugénia Ferreira Manuela Caniça In this study, we report the presence of the plasmid-mediated colistin resistance (PMCR)-encoding gene mcr-1 in an Escherichia coli isolate, INSali25, recovered from lettuce produced and...
Wed Mar 18, 2020 02:00
Microorganisms, Vol. 8, Pages 427: Dietary Carbohydrate Constituents Related to Gut Dysbiosis and Health Microorganisms doi: 10.3390/microorganisms8030427 Authors: Ye Seul Seo Hye-Bin Lee Yoonsook Kim Ho-Young Park Recent studies report that microbiota in the human intestine play an important role in host health and that both long- and short-term diets influence gut microbiota. These findings have fueled interest in the potential of food to promote health by shaping the intestinal...
Wed Mar 18, 2020 02:00
Microorganisms, Vol. 8, Pages 426: Deep Insights into Gut Microbiota in Four Carnivorous Coral Reef Fishes from the South China Sea Microorganisms doi: 10.3390/microorganisms8030426 Authors: Yu-Miao Gao Ke-Shu Zou Lei Zhou Xian-De Huang Yi-Yang Li Xiang-Yang Gao Xiao Chen Xiao-Yong Zhang Investigations of gut microbial diversity among fish to provide baseline data for wild marine fish, especially the carnivorous coral reef fishes of the South China Sea, are lacking....
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1391: Influence of a Commercial Biological Fungicide containing Trichoderma harzianum Rifai T-22 on Dissipation Kinetics and Degradation of Five Herbicides in Two Types of Soil Molecules doi: 10.3390/molecules25061391 Authors: Ewa Szpyrka Magdalena Podbielska Aneta Zwolak Bartosz Piechowicz Grzegorz Siebielec Magdalena Słowik-Borowiec Biological crop protection is recommended to be applied alternately or together with chemical one, to protect...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1389: Synthesis and Antimicrobial Properties of a Ciprofloxacin and PAMAM-dendrimer Conjugate Molecules doi: 10.3390/molecules25061389 Authors: Søren Wedel Svenningsen Rikki Franklin Frederiksen Claire Counil Mario Ficker Jørgen J. Leisner Jørn Bolstad Christensen Infections caused by bacteria resistant to antibiotics are an increasing problem. Multivalent antibiotics could be a solution. In the present study, a covalent conjugate between Ciprofloxacin...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1388: Direct Precipitation of Lignin Nanoparticles from Wheat Straw Organosolv Liquors Using a Static Mixer Molecules doi: 10.3390/molecules25061388 Authors: Stefan Beisl Johannes Adamcyk Anton Friedl Micro- and nanosize lignin shows improved properties compared to standard lignin available today and has been gaining interest in recent years. Lignin is the largest renewable resource with an aromatic skeleton on earth but it is used for relatively low-value...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1390: A Comparative Study on Processed Panax ginseng Products Using HR-MAS NMR-Based Metabolomics Molecules doi: 10.3390/molecules25061390 Authors: Dahye Yoon Woo Cheol Shin Young-Seob Lee Suhkmann Kim Nam-In Baek Dae Young Lee Panax ginseng is processed to diversify efficacy. Four processed ginsengs containing white ginseng (WG), tae-geuk ginseng (TG), red ginseng (RG), and black ginseng (BG) were analyzed using nuclear magnetic resonance (NMR)...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1392: The Metabolic Changes of Artesunate and Ursolic Acid on Syrian Golden Hamsters Fed with the High-Fat Diet Molecules doi: 10.3390/molecules25061392 Authors: Shichen Pu Yumin Liu Shan Liang Pin Liu Hongmei Qian Qian Wu Yuliang Wang Artesunate was well known as an antimalarial drug. Our previous research found that it has hypolipidemia effects in rabbits fed with a high-fat diet, especially combined with ursolic acid. In this study, we reconfirmed...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1387: Partial Least Square Model (PLS) as a Tool to Predict the Diffusion of Steroids Across Artificial Membranes Molecules doi: 10.3390/molecules25061387 Authors: Eleni Tsanaktsidou Christina Karavasili Constantinos K. Zacharis Dimitrios G. Fatouros Catherine K. Markopoulou One of the most challenging goals in modern pharmaceutical research is to develop models that can predict drugs’ behavior, particularly permeability in human tissues....
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1384: A Novel Alternative in the Treatment of Detrusor Overactivity? In Vivo Activity of O-1602, the Newly Synthesized Agonist of GPR55 and GPR18 Cannabinoid Receptors Molecules doi: 10.3390/molecules25061384 Authors: Andrzej Wróbel Aleksandra Szopa Anna Serefko Ewa Poleszak The aim of the research was to assess the impact of O-1602—novel GPR55 and GPR18 agonist—in the rat model of detrusor overactivity (DO). Additionally, its effect...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1386: Protective Effect of Astaxanthin on Ochratoxin A-Induced Kidney Injury to Mice by Regulating Oxidative Stress-Related NRF2/KEAP1 Pathway Molecules doi: 10.3390/molecules25061386 Authors: Lin Li Yueli Chen Danyang Jiao Shuhua Yang Lin Li Peng Li The present study aimed to investigate the effects of astaxanthin (ASX) on ochratoxin A (OTA)-induced renal oxidative stress and its mechanism of action. Serum kidney markers, histomorphology, ultrastructural...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1385: Anti-Inflammatory Effects of Neochlorogenic Acid Extract from Mulberry Leaf (Morus alba L.) Against LPS-Stimulated Inflammatory Response through Mediating the AMPK/Nrf2 Signaling Pathway in A549 Cells Molecules doi: 10.3390/molecules25061385 Authors: Xiao-han Gao Sun-dong Zhang Li-tao Wang Liang Yu Xue-lian Zhao Hai-yan Ni Yan-qiu Wang Jian-dong Wang Chun-hua Shan Yu-jie Fu Neochlorogenic acid (nCGA) is a phenolic compound isolated...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1383: State-of-the-Art Production Chains for Peas, Beans and Chickpeas—Valorization of Agro-Industrial Residues and Applications of Derived Extracts Molecules doi: 10.3390/molecules25061383 Authors: Annalisa Tassoni Tullia Tedeschi Chiara Zurlini Ilaria Maria Cigognini Janos-Istvan Petrusan Óscar Rodríguez Simona Neri Annamaria Celli Laura Sisti Patrizia Cinelli Francesca Signori Georgios Tsatsos Marika Bondi Stefanie Verstringe...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1382: Identification of Interleukin-8-Reducing Lead Compounds Based on SAR Studies on Dihydrochalcone-Related Compounds in Human Gingival Fibroblasts (HGF-1 cells) In Vitro Molecules doi: 10.3390/molecules25061382 Authors: Katharina Schueller Joachim Hans Stefanie Pfeiffer Jessica Walker Jakob P. Ley Veronika Somoza Background: In order to identify potential activities against periodontal diseases, eighteen dihydrochalcones and structurally related...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1381: Influence of Altitude on Phytochemical Composition of Hemp Inflorescence: A Metabolomic Approach Molecules doi: 10.3390/molecules25061381 Authors: Luca Giupponi Valeria Leoni Radmila Pavlovic Annamaria Giorgi The phytochemical profiling of hemp inflorescences of clonal plants growing in different conditions related to altitude was investigated. Four strains of industrial hemp (Cannabis sativa L., family Cannabaceae) of Kompolti variety were selected...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1380: Systematic Investigation of Insulin Fibrillation on a Chip Molecules doi: 10.3390/molecules25061380 Authors: Hoon Suk Rho Henk-Willem Veltkamp Alexander Thomas Hanke Marcel Ottens Christian Breukers Pamela Habibović Han Gardeniers A microfluidic protein aggregation device (microPAD) that allows the user to perform a series of protein incubations with various concentrations of two reagents is demonstrated. The microfluidic device consists...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1378: Freeze Granulated Zeolites X and A for Biogas Upgrading Molecules doi: 10.3390/molecules25061378 Authors: Kritika Narang Farid Akhtar Biogas is a potential renewable energy resource that can reduce the current energy dependency on fossil fuels. The major limitation of utilizing biogas fully in the various applications is the presence of a significant volume fraction of carbon dioxide in biogas. Here, we used adsorption-driven CO2 separation using the...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1379: Effect of Terpenoids and Flavonoids Isolated from Baccharis conferta Kunth on TPA-Induced Ear Edema in Mice Molecules doi: 10.3390/molecules25061379 Authors: Gutiérrez-Román Ana Silvia Trejo-Tapia Gabriela Herrera-Ruiz Maribel Monterrosas-Brisson Nayeli Trejo-Espino José Luis Zamilpa Alejandro González-Cortazar Manasés In this study, we isolated from the aerial parts of Baccharis conferta Kunth (i) a new neoclerodane, denominated “bacchofertone”;...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1377: Synthesis, Characterization and Biological Evaluation of Novel Dihydropyranoindoles Improving the Anticancer Effects of HDAC Inhibitors Molecules doi: 10.3390/molecules25061377 Authors: Murat Bingul Greg M. Arndt Glenn M. Marshall Belamy B. Cheung Naresh Kumar David StC. Black The dihydropyranoindole scaffold was identified as a promising target for improving the anti-cancer activity of HDAC inhibitors from the preliminary screening of a...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1376: Effect of Systemic Subnormal Deuterium Level on Metabolic Syndrome Related and other Blood Parameters in Humans: A Preliminary Study Molecules doi: 10.3390/molecules25061376 Authors: Gábor Somlyai Ildikó Somlyai István Fórizs György Czuppon András Papp Miklós Molnár The effects of deuterium depletion on the human organism have been, except for the antitumor action, seldom investigated by now and the available data are scarce. In oncological...
Wed Mar 18, 2020 02:00
Molecules, Vol. 25, Pages 1375: A Review on Applications of Computational Methods in Drug Screening and Design Molecules doi: 10.3390/molecules25061375 Authors: Xiaoqian Lin Xiu Li Xubo Lin Drug development is one of the most significant processes in the pharmaceutical industry. Various computational methods have dramatically reduced the time and cost of drug discovery. In this review, we firstly discussed roles of multiscale biomolecular simulations in identifying drug binding...
Wed Mar 18, 2020 02:00
Nanomaterials, Vol. 10, Pages 551: Construction of Time-Resolved Luminescence Nanoprobe and Its Application in As(III) Detection Nanomaterials doi: 10.3390/nano10030551 Authors: Teng Chen Haitao Wang Zhouping Wang Mingqian Tan As(III) is a toxic heavy metal which causes serious health problems. Therefore, the development of highly sensitive sensors for As(III) detection is of great significance. Herein, a turn-on luminescence resonance energy transfer (LRET) method based on...
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Nanomaterials, Vol. 10, Pages 548: Functionalization of Gold Nanoparticles by Inorganic Entities Nanomaterials doi: 10.3390/nano10030548 Authors: Frédéric Dumur Eddy Dumas Cédric R. Mayer The great affinity of gold surface for numerous electron-donating groups has largely contributed to the rapid development of functionalized gold nanoparticles (Au-NPs). In the last years, a new subclass of nanocomposite has emerged, based on the association of inorganic molecular entities (IME)...
Wed Mar 18, 2020 02:00
Nanomaterials, Vol. 10, Pages 549: Amplified Fluorescence by ZnO Nanoparticles vs. Quantum Dots for Bovine Mastitis Acute Phase Response Evaluation in Milk Nanomaterials doi: 10.3390/nano10030549 Authors: Narsingh R. Nirala Giorgi Shtenberg Bovine mastitis (BM) is a prominent inflammatory disease affecting the dairy industry worldwide, originated by pathogenic agent invasion onto the mammary gland. The early detection of new BM cases is of high importance for infection control within...
Wed Mar 18, 2020 02:00
Nanomaterials, Vol. 10, Pages 550: Gene Expression and Epigenetic Changes in Mice Following Inhalation of Copper(II) Oxide Nanoparticles Nanomaterials doi: 10.3390/nano10030550 Authors: Pavel Rossner Kristyna Vrbova Andrea Rossnerova Tana Zavodna Alena Milcova Jiri Klema Zbynek Vecera Pavel Mikuska Pavel Coufalik Lukas Capka Kamil Krumal Bohumil Docekal Vladimir Holan Miroslav Machala Jan Topinka We investigated the transcriptomic response and...
Wed Mar 18, 2020 02:00
Nanomaterials, Vol. 10, Pages 546: Effects of Particle Size on the Structure and Photocatalytic Performance by Alkali-Treated TiO2 Nanomaterials doi: 10.3390/nano10030546 Authors: Danqi Li Hongchen Song Xia Meng Tingting Shen Jing Sun Wenjia Han Xikui Wang Particle size of nanomaterials has significant impact on their photocatalyst properties. In this paper, TiO2 nanoparticles with different crystalline sizes were prepared by adjusting the alkali-hydrothermal time (0–48...
Wed Mar 18, 2020 02:00
Nanomaterials, Vol. 10, Pages 547: Solar Cell Applications of Solution-Processed AgInGaSe2 Thin Films and Improved Properties by Sodium Doping Nanomaterials doi: 10.3390/nano10030547 Authors: Xianfeng Zhang Qingxuan Sun Maoxi Zheng Zhuohua Duan Yuehui Wang Binary nanoparticle inks comprising Ag2Se, In2Se3, and Ga2Se3 were fabricated via a wet ball-milling method and were further used to fabricate AgInGaSe2 (AIGS) precursors by sequentially spraying the inks onto a Mo-coated...
Wed Mar 18, 2020 02:00
Nanomaterials, Vol. 10, Pages 545: Hepato(Geno)Toxicity Assessment of Nanoparticles in a HepG2 Liver Spheroid Model Nanomaterials doi: 10.3390/nano10030545 Authors: Elisabeth Elje Espen Mariussen Oscar H. Moriones Neus G. Bastús Victor Puntes Yvonne Kohl Maria Dusinska Elise Rundén-Pran (1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the development of advanced in vitro models is needed for nanotoxicity assessment. Cells cultivated...
Wed Mar 18, 2020 02:00
Nanomaterials, Vol. 10, Pages 543: Making Nd3+ a Sensitive Luminescent Thermometer for Physiological Temperatures—An Account of Pitfalls in Boltzmann Thermometry Nanomaterials doi: 10.3390/nano10030543 Authors: Markus Suta Željka Antić Vesna Ðorđević Sanja Kuzman Miroslav D. Dramićanin Andries Meijerink Ratiometric luminescence thermometry employing luminescence within the biological transparency windows provides high potential for biothermal imaging. Nd3+ is a promising...
Wed Mar 18, 2020 02:00
Nanomaterials, Vol. 10, Pages 544: Globular Flower-Like Reduced Graphene Oxide Design for Enhancing Thermally Conductive Properties of Silicone-Based Spherical Alumina Composites Nanomaterials doi: 10.3390/nano10030544 Authors: Weijie Liang Tiehu Li Xiaocong Zhou Xin Ge Xunjun Chen Zehua Lin Xiaoyan Pang Jianfang Ge The enhancement of thermally conductive performances for lightweight thermal interface materials is a long-term effort. The superb micro-structures of...
Wed Mar 18, 2020 02:00
Nutrients, Vol. 12, Pages 806: Detection of Early Disease Risk Factors Associated with Metabolic Syndrome: A New Era with the NMR Metabolomics Assessment Nutrients doi: 10.3390/nu12030806 Authors: Julia Hernandez-Baixauli Sergio Quesada-Vázquez Roger Mariné-Casadó Katherine Gil Gil Cardoso Antoni Caimari Josep M Del Del Bas Xavier Escoté Laura Baselga-Escudero The metabolic syndrome is a multifactorial disease developed due to accumulation and chronification of several...
Wed Mar 18, 2020 02:00
Nutrients, Vol. 12, Pages 807: The Role of Post-Ingestive Feedback in the Development of an Enhanced Appetite for the Orosensory Properties of Glucose over Fructose in Rats Nutrients doi: 10.3390/nu12030807 Authors: Kevin P. Myers Megan Y. Summers Elizabeth Geyer-Roberts Lindsey A. Schier The simple sugars glucose and fructose share a common “sweet” taste quality mediated by the T1R2+T1R3 taste receptor. However, when given the opportunity to consume each...
Wed Mar 18, 2020 02:00
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