IJMS, Vol. 21, Pages 2312: Exosomal MicroRNAs Released by Activated Astrocytes as Potential Neuroinflammatory Biomarkers International Journal of Molecular Sciences doi: 10.3390/ijms21072312 Authors: Manoshi Gayen Manish Bhomia Nagaraja Balakathiresan Barbara Knollmann-Ritschel Neuroinflammation is a hallmark of several neurodegenerative diseases and disorders, including traumatic brain injury (TBI). Neuroinflammation results in the activation of glial cells which exacerbates...
Fri Mar 27, 2020 02:00
IJMS, Vol. 21, Pages 2311: Tailored PCL Scaffolds as Skin Substitutes Using Sacrificial PVP Fibers and Collagen/Chitosan Blends International Journal of Molecular Sciences doi: 10.3390/ijms21072311 Authors: Ali Reza Sadeghi-avalshahr Samira Nokhasteh Amir Mahdi Molavi Najmeh Mohammad-pour Mohammad Sadeghi Electrospinning is a versatile technique for fabrication of made-on-purpose biomimetic scaffolds. In this study, optimized electrospun fibrous membranes were produced by...
Fri Mar 27, 2020 02:00
IJMS, Vol. 21, Pages 2310: Characterization and Comparison of Human and Ovine Mesenchymal Stromal Cells from Three Corresponding Sources International Journal of Molecular Sciences doi: 10.3390/ijms21072310 Authors: El-Mustapha Haddouti Thomas M. Randau Cäcilia Hilgers Werner Masson Klaus J. Walgenbach Robert Pflugmacher Christof Burger Sascha Gravius Frank A. Schildberg Currently, there is an increasing focus on mesenchymal stromal cells (MSC) as therapeutic...
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 937: Desminopathy: Novel Desmin Variants, a New Cardiac Phenotype, and Further Evidence for Secondary Mitochondrial Dysfunction Journal of Clinical Medicine doi: 10.3390/jcm9040937 Authors: Miloš Kubánek Tereza Schimerová Lenka Piherová Andreas Brodehl Alice Krebsová Sandra Ratnavadivel Caroline Stanasiuk Hana Hansíková Jiří Zeman Tomáš Paleček Josef Houštěk Zdeněk Drahota Hana Nůsková Jana Mikešová Josef Zámečník Milan Macek...
Sun Mar 29, 2020 02:00
JCM, Vol. 9, Pages 935: Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer—Results from the AGMT GASTRIC-5 Registry Journal of Clinical Medicine doi: 10.3390/jcm9040935 Authors: Huemer Weiss Regitnig Winder Hartmann Thaler Piringer Schmitt Eisterer Gänzer Wüstner Andel Jagdt Ulmer Greil Wöll Trastuzumab in combination with a platinum and fluorouracil is the treatment...
Sun Mar 29, 2020 02:00
JCM, Vol. 9, Pages 934: MRI study of paraspinal muscles in patients with Amyotrophic Lateral Sclerosis (ALS) Journal of Clinical Medicine doi: 10.3390/jcm9040934 Authors: Diamanti Paoletti Vita Muzic Cereda Ballante Pichiecchio Background: the study of paraspinal muscles is pivotal for the diagnosis and staging of Amyotrophic Lateral Sclerosis (ALS), and is usually performed by electromyography. Objective: to evaluate the role of paraspinal muscle MRI as a diagnostic...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 936: Impact of Decorin on the Physical Function and Prognosis of Patients with Hepatocellular Carcinoma Journal of Clinical Medicine doi: 10.3390/jcm9040936 Authors: Takumi Kawaguchi Sachiyo Yoshio Yuzuru Sakamoto Ryuki Hashida Shunji Koya Keisuke Hirota Dan Nakano Sakura Yamamura Takashi Niizeki Hiroo Matsuse Takuji Torimura The outcome of patients with hepatocellular carcinoma (HCC) is still poor. Decorin is a small leucine-rich proteoglycan,...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 931: Patient Characteristics, Treatment and Outcome in Non-Ischemic vs. Ischemic Cardiogenic Shock Journal of Clinical Medicine doi: 10.3390/jcm9040931 Authors: Schrage Weimann Dabboura Yan Hilal Becher Seiffert Bernhardt Kluge Reichenspurner Blankenberg Westermann : Aim: Evidence on non-ischemic cardiogenic shock (CS) is scarce. The aim of this study was to investigate differences in patient characteristics, use of treatments...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 929: Salivary Biomarkers and Their Correlation with Pain and Stress in Patients with Burning Mouth Syndrome Journal of Clinical Medicine doi: 10.3390/jcm9040929 Authors: Lopez-Jornet Felipe Pardo-Marin Ceron Pons-Fuster Tvarijonaviciute Objective: To evaluate a panel of salivary analytes involving biomarkers of inflammation, stress, immune system and antioxidant status in patients with burning mouth syndrome (BMS) and to study their relationship...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 928: Effect of Proton Pump Inhibitors on Risks of Upper and Lower Gastrointestinal Bleeding among Users of Low-Dose Aspirin: A Population-Based Observational Study Journal of Clinical Medicine doi: 10.3390/jcm9040928 Authors: Luis A. García Rodríguez Angel Lanas Montse Soriano-Gabarró Pareen Vora Lucía Cea Soriano Estimates of the effect of proton pump inhibitors (PPIs) on risks of upper and lower gastrointestinal bleeding (UGIB and LGIB) among low-dose...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 930: Angiogenesis and Immunity in Renal Carcinoma: Can We Turn an Unhappy Relationship into a Happy Marriage? Journal of Clinical Medicine doi: 10.3390/jcm9040930 Authors: Alessia Mennitto Veronica Huber Raffaele Ratta Pierangela Sepe Filippo de Braud Giuseppe Procopio Valentina Guadalupi Mélanie Claps Marco Stellato Elena Daveri Licia Rivoltini Elena Verzoni The frontline treatment options for patients with metastatic renal cell carcinoma...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 927: Calprotectin and Receptor for Advanced Glycation End Products as a Potential Biomarker in Abdominal Aortic Aneurysm Journal of Clinical Medicine doi: 10.3390/jcm9040927 Authors: Willy Hauzer Wojciech Witkiewicz Jan Gnus Experiments conducted in recent years on animals and research works worldwide show a linkage between calprotectin and occurrence and development of the abdominal aortic aneurysm (AAA). Additionally, a correlation between the level of the...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 925: Associations between the Quality of Life and Nasal Polyp Size in Patients Suffering from Chronic Rhinosinusitis without Nasal Polyps, with Nasal Polyps or Aspirin-Exacerbated Respiratory Disease Journal of Clinical Medicine doi: 10.3390/jcm9040925 Authors: Sven Schneider Nicholas J. Campion Sergio Villazala-Merino David Tianxiang Liu Tina Bartosik Lukas D. Landegger Navid Ahmadi Christian A. Mueller Erich Vyskocil Victoria Stanek Tamara...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 924: Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress Journal of Clinical Medicine doi: 10.3390/jcm9040924 Authors: Nath Pigula Khan Hanna Ruhi Dehkordy Pushpavanam Rege Moore Tsujita Conrad Inci Carmen Franco Celli Demirci Hasan Huang Rizvi A key reason...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 926: Can an Observational Gait Scale Produce a Result Consistent with Symmetry Indexes Obtained from 3-Dimensional Gait Analysis?: A Concurrent Validity Study Journal of Clinical Medicine doi: 10.3390/jcm9040926 Authors: Agnieszka Guzik Mariusz Drużbicki Lidia Perenc Justyna Podgórska-Bednarz To investigate whether a simple observational tool may be a substitute to the time-consuming and costly 3-dimensional (3D) analysis, the study applied the Wisconsin Gait...
Sat Mar 28, 2020 02:00
JCM, Vol. 9, Pages 919: Potential Adverse Drug Events with Tetrahydrocannabinol (THC) Due to Drug–Drug Interactions Journal of Clinical Medicine doi: 10.3390/jcm9040919 Authors: Brown Tetrahydrocannabinol (THC) is the primary psychoactive ingredient in cannabis. While the safety of THC and cannabis has been extrapolated from millennia of recreational use, medical marijuana programs have increased exposure among medically complex individuals with comorbid conditions and many co-prescribed...
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 922: Circadian Patterns in Postvoid Residual and Voided Percentage Among Older Women with Urinary Incontinence Journal of Clinical Medicine doi: 10.3390/jcm9040922 Authors: Decalf Monaghan Denys Petrovic Pieters Weiss Everaert Background: Women with urinary incontinence incur an increased risk of elevated postvoid residual (PVR) volume and impaired voiding efficiency (i.e., voided percentage (Void%)), but the clinical significance of these...
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 921: Effective Asthma Management: Is It Time to Let the AIR out of SABA? Journal of Clinical Medicine doi: 10.3390/jcm9040921 Authors: Kaplan Mitchell Cave Gagnon Foran Ellis For years, standard asthma treatment has included short acting beta agonists (SABA), including as monotherapy in patients with mild asthma symptoms. In the Global Initiative for Asthma 2019 strategy for the management of asthma, the authors recommended a significant departure...
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 920: The Public Health Burden of Cardiomyopathies: Insights from a Nationwide Inpatient Study Journal of Clinical Medicine doi: 10.3390/jcm9040920 Authors: Lannou Mansencal Couchoud Lassalle Dubourg Stengel Jacquelinet Charron Cardiomyopathies are responsible for heart failure and sudden cardiac death, but epidemiological data are scarce and the public health burden may be underestimated. We studied aggregating data from all public or private...
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 923: Prevention and Management of the Post-Thrombotic Syndrome Journal of Clinical Medicine doi: 10.3390/jcm9040923 Authors: Makedonov Kahn Galanaud The post-thrombotic syndrome (PTS) is a form of chronic venous insufficiency secondary to prior deep vein thrombosis (DVT). It affects up to 50% of patients after proximal DVT. There is no effective treatment of established PTS and its management lies in its prevention after DVT. Optimal anticoagulation is key...
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 916: Assessment of the Efficacy of Lowering LDL Cholesterol with Rosuvastatin 10 mg in Four Korean Statin Benefit Groups as per ACC/AHA Guidelines (NewStaR4G) Journal of Clinical Medicine doi: 10.3390/jcm9040916 Authors: Kyung-Jin Kim Junghan Yoon Kyung Heon Won Sang-Wook Lim In-Ho Chae Sung Yun Lee Sang-Wook Kim Hyo-Soo Kim The American College of Cardiology and American Heart Association (ACC/AHA) guidelines identified four statin benefit groups...
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 917: Thulium Laser Vapoenucleation of the Prostate (ThuVEP) in Men at High Cardiovascular Risk and on Antithrombotic Therapy: A Single-Center Experience Journal of Clinical Medicine doi: 10.3390/jcm9040917 Authors: Daniele Castellani Mirko Di Rosa Luca Gasparri Michele Pucci Marco Dellabella Bleeding is the most common complication of transurethral resection of the prostate and simple open prostatectomy, especially in men on antiplatelet/anticoagulant therapy....
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 918: The Vascular Side of Chronic Bed Rest: When a Therapeutic Approach Becomes Deleterious Journal of Clinical Medicine doi: 10.3390/jcm9040918 Authors: Pedrinolla Colosio Magliozzi Danese Kirmizi Rossi Pogliaghi Calabrese Gelati Muti Cè Longo Esposito Lippi Schena Venturelli The interplay between chronic constraint and advanced aging on blood flow, shear-rate, vascular function, nitric oxide (NO)-bioavailability,...
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 915: Deproteinization as a Rapid Method of Saliva Purification for the Determination of Carbamazepine and Carbamazepine-10,11 Epoxide Journal of Clinical Medicine doi: 10.3390/jcm9040915 Authors: Ewelina Dziurkowska Marek Wesolowski Saliva is a valuable diagnostic material that, in some cases, may replace blood. However, because of its different composition, its use requires the development of new, or the modification of existing, extraction procedures. Therefore,...
Fri Mar 27, 2020 02:00
JCM, Vol. 9, Pages 914: The Effect of Exercise Training on Brain Structure and Function in Older Adults: A Systematic Review Based on Evidence from Randomized Control Trials Journal of Clinical Medicine doi: 10.3390/jcm9040914 Authors: Chen Hopman Huang Chu Hillman Hung Chang Accumulating evidence suggests that exercise training is associated with improvements in brain health in older adults, yet the extant literature is insufficient in detailing why exercise...
Fri Mar 27, 2020 02:00
JoF, Vol. 6, Pages 43: Impact of ITS-Based Sequencing on Antifungal Treatment of Patients with Suspected Invasive Fungal Infections Journal of Fungi doi: 10.3390/jof6020043 Authors: Guenter Gorkiewicz Halwachs Kashofer Thueringer Wurm Zollner-Schwetz Valentin Prattes Wunsch Ullrich Zurl Hoenigl Krause Molecular techniques including the sequencing of fungal-specific DNA targets are increasingly used in the diagnosis of suspected invasive...
Fri Mar 27, 2020 02:00
J. Imaging, Vol. 6, Pages 15: A New Pseudo-Spectral Method Using the Discrete Cosine Transform Journal of Imaging doi: 10.3390/jimaging6040015 Authors: Izumi Ito The pseudo-spectral (PS) method on the basis of the Fourier transform is a numerical method for estimating derivatives. Generally, the discrete Fourier transform (DFT) is used when implementing the PS method. However, when the values on both sides of the sequences differ significantly, oscillatory approximations around both...
Sat Mar 28, 2020 02:00
Medicina, Vol. 56, Pages 152: Synchronous Cervical Adenocarcinoma and Ovarian Serous Adenocarcinoma—A Case Report and Literature Review Medicina doi: 10.3390/medicina56040152 Authors: Nicolae Bacalbasa Irina Cecilia Balescu Camelia Diaconu Simona Dima Laura Iliescu Mihaela Vilcu Alexandru Filipescu Ioana Halmaciu Dragos Cretoiu Iulian Brezean Background/Aim: Synchronous gynecological malignancies are rarely encountered, and most often these cases are represented...
Sun Mar 29, 2020 02:00
Medicina, Vol. 56, Pages 151: Comparison of Subjective Workout Intensities between Aquatic and Land-based Running in Healthy Young Males: A Pilot Study Medicina doi: 10.3390/medicina56040151 Authors: Chang-Hyung Lee Jun Hwan Choi Soo-Yeon Kim Background and objectives: Aquatic exercises have demonstrated several advantages over land-based exercise, but only a few studies have compared the workout intensities and efficiencies in a stage-specific manner. This study aimed to investigate...
Sat Mar 28, 2020 02:00
Medicina, Vol. 56, Pages 150: Implementation of the Obturator Nerve Block into a Supra-Inguinal Fascia Iliaca Compartment Block Based Analgesia Protocol for Hip Arthroscopy: Retrospective Pre-Post Study Medicina doi: 10.3390/medicina56040150 Authors: Lee Hwang Lee Eom Oh Chung Ko Lee Hong Hwang Background and Objectives: The effect of supra-inguinal fascia iliaca compartment block (SI-FICB) in hip arthroscopy is not apparent. It is also controversial...
Fri Mar 27, 2020 02:00
Medicines, Vol. 7, Pages 16: Stem Cell Ophthalmology Treatment Study (SCOTS): Bone Marrow-Derived Stem Cells in the Treatment of Age-Related Macular Degeneration Medicines doi: 10.3390/medicines7040016 Authors: Jeffrey N. Weiss Steven Levy Background: Dry age-related macular degeneration (AMD) is one of the leading causes of vision loss in older patients. The macula accumulates drusen with loss of retinal pigment epithelial cells and photoreceptors. Abnormal subretinal neovascularization...
Sat Mar 28, 2020 02:00
Membranes, Vol. 10, Pages 58: The Influence of Graphene Addition on the Properties of Composite rGO/PAN Membranes and Their Potential Application for Water Disinfection Membranes doi: 10.3390/membranes10040058 Authors: Fryczkowska Machnicka Biniaś Ślusarczyk Fabia The paper presents a method of obtaining composite polyacrylonitrile-based (PAN) membranes with the addition of reduced graphene oxide (rGO). The membranes were obtained using phase inversion method from a...
Sun Mar 29, 2020 02:00
Membranes, Vol. 10, Pages 56: Enhancing the Separation Performance of Glassy PPO with the Addition of a Molecular Sieve (ZIF-8): Gas Transport at Various Temperatures Membranes doi: 10.3390/membranes10040056 Authors: Benedetti De Angelis Esposti Fabbri Masili Orsini Pettinau In this study, we prepared and characterized composite films formed by amorphous poly(2,6-dimethyl-1,4-phenylene oxide) (PPO) and particles of the size-selective Zeolitic Imidazolate Framework...
Fri Mar 27, 2020 02:00
Metabolites, Vol. 10, Pages 130: Suggestions for Standardized Identifiers for Fatty Acyl Compounds in Genome Scale Metabolic Models and Their Application to the WormJam Caenorhabditis elegans Model Metabolites doi: 10.3390/metabo10040130 Authors: Witting Genome scale metabolic models (GSMs) are a representation of the current knowledge on the metabolism of a given organism or superorganism. They group metabolites, genes, enzymes and reactions together to form a mathematical model and...
Sat Mar 28, 2020 02:00
Metabolites, Vol. 10, Pages 129: Current Concepts in Pharmacometabolomics, Biomarker Discovery, and Precision Medicine Metabolites doi: 10.3390/metabo10040129 Authors: Richard D. Beger Michael A Schmidt Rima Kaddurah-Daouk Pharmacometabolomics (PMx) studies use information contained in metabolic profiles (or metabolome) to inform about how a subject will respond to drug treatment. Genome, gut microbiome, sex, nutrition, age, stress, health status, and other factors can impact the...
Fri Mar 27, 2020 02:00
Metabolites, Vol. 10, Pages 128: The ABRF Metabolomics Research Group 2016 Exploratory Study: Investigation of Data Analysis Methods for Untargeted Metabolomics Metabolites doi: 10.3390/metabo10040128 Authors: Christoph W. Turck Tytus D Mak Maryam Goudarzi Reza M Salek Amrita K Cheema Lack of standardized applications of bioinformatics and statistical approaches for pre- and postprocessing of global metabolomic profiling data sets collected using high-resolution mass spectrometry...
Fri Mar 27, 2020 02:00
MPs, Vol. 3, Pages 26: Exploring Patient Views and Acceptance of Multiparametric Magnetic Resonance Imaging for the Investigation of Suspected Prostate Cancer (the PACT Study): A Mixed-Methods Study Protocol Methods and Protocols doi: 10.3390/mps3020026 Authors: Joseph M. Norris Veeru Kasivisvanathan Clare Allen Rhys Ball Alex Freeman Maneesh Ghei Alex Kirkham Hayley C. Whitaker Daniel Kelly Mark Emberton BACKGROUND: The introduction of multiparametric magnetic...
Sat Mar 28, 2020 02:00
Microorganisms, Vol. 8, Pages 486: Soybean Oil Modulates the Gut Microbiota Associated with Atherogenic Biomarkers Microorganisms doi: 10.3390/microorganisms8040486 Authors: Hila Korach-Rechtman Oren Rom Lirane Mazouz Shay Freilich Helana Jeries Tony Hayek Michael Aviram Yechezkel Kashi During the last few decades there has been a staggering rise in human consumption of soybean-oil (SO). The microbiome and specific taxa composing it are dramatically affected by diet;...
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Microorganisms, Vol. 8, Pages 485: Characterization of the Duodenal Mucosal Microbiome in Obese Adult Subjects by 16S rRNA Sequencing Microorganisms doi: 10.3390/microorganisms8040485 Authors: Carmela Nardelli Ilaria Granata Valeria D'Argenio Salvatore Tramontano Debora Compare Mario Rosario Guarracino Gerardo Nardone Vincenzo Pilone Lucia Sacchetti The gut microbiota may have an impact on obesity. To date, the majority of studies in obese patients reported microbiota...
Sun Mar 29, 2020 02:00
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