Pathogens, Vol. 9, Pages 198: Mixed Aetiology of Diarrhoea in Infants Attending Clinics in the North-West Province of South Africa: Potential for Sub-Optimal Treatment Pathogens doi: 10.3390/pathogens9030198 Authors: Chukwu Abia Ubomba-Jaswa Dewar Obi Routine diagnostic methods for the aetiologic agents of diarrhoea in most developing countries are usually not sensitive enough, leading to under-diagnosis. Thus, this study investigated possible mixed diarrhoeal aetiology...
Fri Mar 06, 2020 02:00
Pathogens, Vol. 9, Pages 196: Wild Birds in Live Birds Markets: Potential Reservoirs of Enzootic Avian Influenza Viruses and Antimicrobial Resistant Enterobacteriaceae in Northern Egypt Pathogens doi: 10.3390/pathogens9030196 Authors: Nabil Erfan Tawakol Haggag Naguib Samy Wild migratory birds are often implicated in the introduction, maintenance, and global dissemination of different pathogens, such as influenza A viruses (IAV) and antimicrobial-resistant (AMR)...
Fri Mar 06, 2020 02:00
Pathogens, Vol. 9, Pages 195: Lineage, Antimicrobial Resistance and Virulence of Citrobacter spp Pathogens doi: 10.3390/pathogens9030195 Authors: Liu Qin Hao Lan Xu Guo Jiang Sun Chen LV Xu Zhao Citrobacter spp. are opportunistic human pathogens which can cause nosocomial infections, sporadic infections and outbreaks. In order to determine the genetic diversity, in vitro virulence properties and antimicrobial resistance profiles of Citrobacter...
Fri Mar 06, 2020 02:00
Pathogens, Vol. 9, Pages 197: Animal Models of Lassa Fever Pathogens doi: 10.3390/pathogens9030197 Authors: Rachel A. Sattler Slobodan Paessler Hinh Ly Cheng Huang Lassa virus (LASV), the causative agent of Lassa fever, is estimated to be responsible for up to 300,000 new infections and 5000 deaths each year across Western Africa. The most recent 2018 and 2019 Nigerian outbreaks featured alarmingly high fatality rates of up to 25.4%. In addition to the severity and high fatality...
Fri Mar 06, 2020 02:00
Pharmaceuticals, Vol. 13, Pages 42: Is There a Role for the Therapeutic Drug Monitoring of Colistin? An Overview Pharmaceuticals doi: 10.3390/ph13030042 Authors: Maria-Paula Avila Tatiana Pacheco Sara Arias Rosa-Helena Bustos Julio-Cesar Garcia Diego Jaimes Colistin is used as a last-line antibiotic for the treatment of Gram-negative multiresistant bacteria. Due to its high nephrotoxicity, Therapeutic Drug Monitoring (TDM) is recommended for dose adjustment. We aimed to...
Fri Mar 06, 2020 02:00
Pharmaceutics, Vol. 12, Pages 243: A Novel Bivalent Mannosylated Targeting Ligand Displayed on Nanoparticles Selectively Targets Anti-Inflammatory M2 Macrophages Pharmaceutics doi: 10.3390/pharmaceutics12030243 Authors: Peiming Chen Xiaoping Zhang Alessandro Venosa In Heon Lee Daniel Myers Jennifer A. Holloway Robert K. Prud’homme Dayuan Gao Zoltan Szekely Jeffery D. Laskin Debra L. Laskin Patrick J. Sinko Persistent activation of macrophages (MP)s into...
Sun Mar 08, 2020 02:00
Pharmaceutics, Vol. 12, Pages 245: Development of an Orodispersible Film Containing Stabilized Influenza Vaccine Pharmaceutics doi: 10.3390/pharmaceutics12030245 Authors: Yu Tian Yoshita C. Bhide Herman J. Woerdenbag Anke L. W. Huckriede Henderik W. Frijlink Wouter L. J. Hinrichs J. Carolina Visser Most influenza vaccines are administered via injection, which is considered as user-unfriendly. Vaccination via oral cavity using an orodispersible film (ODF) might be a...
Sun Mar 08, 2020 02:00
Pharmaceutics, Vol. 12, Pages 244: Application of Multiple Linear Regression and Artificial Neural Networks for the Prediction of the Packing and Capsule Filling Performance of Coated and Plain Pellets Differing in Density and Size Pharmaceutics doi: 10.3390/pharmaceutics12030244 Authors: Panagiotis Barmpalexis Ioannis Partheniadis Konstantina-Sepfora Mitra Miltiadis Toskas Labrini Papadopoulou Ioannis Nikolakakis Plain or coated pellets of different densities 1.45, 2.53,...
Sun Mar 08, 2020 02:00
Pharmaceutics, Vol. 12, Pages 242: Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat Pharmaceutics doi: 10.3390/pharmaceutics12030242 Authors: David Dahlgren Maria-Jose Cano-Cebrián Tobias Olander Mikael Hedeland Markus Sjöblom Hans Lennernäs Sufficient colonic absorption is necessary for all systemically acting drugs in dosage forms that release the drug in the large intestine. Preclinically, colonic absorption is often investigated using...
Sun Mar 08, 2020 02:00
Pharmaceutics, Vol. 12, Pages 241: Mucoadhesive Buccal Films for Local Delivery of Lactobacillus brevis Pharmaceutics doi: 10.3390/pharmaceutics12030241 Authors: Angela Abruzzo Beatrice Vitali Francesca Lombardi Luca Guerrini Benedetta Cinque Carola Parolin Federica Bigucci Teresa Cerchiara Catia Arbizzani Maria Caterina Gallucci Barbara Luppi The aim of this work was to prepare mucoadhesive buccal films for local release of Lactobacillus brevis CD2, which...
Sun Mar 08, 2020 02:00
Pharmaceutics, Vol. 12, Pages 240: Solid-in-Oil Nanodispersions for Transcutaneous Immunotherapy of Japanese Cedar Pollinosis Pharmaceutics doi: 10.3390/pharmaceutics12030240 Authors: Qingliang Kong Momoko Kitaoka Rie Wakabayashi Yoshiro Tahara Noriho Kamiya Masahiro Goto Japanese cedar pollinosis (JCP) is a common affliction caused by an allergic reaction to cedar pollen and is considered a disease of national importance in Japan. Antigen-specific immunotherapy (AIT)...
Sat Mar 07, 2020 02:00
Pharmaceutics, Vol. 12, Pages 239: Light-Activatable Transfection System Using Hybrid Vectors Composed of Thermosensitive Dendron Lipids and Gold Nanorods Pharmaceutics doi: 10.3390/pharmaceutics12030239 Authors: Takuya Hashimoto Tomoya Hirata Eiji Yuba Atsushi Harada Kenji Kono Background: Gene delivery to target cells is crucially important to establish gene therapy and regenerative medicine. Although various virus-based and synthetic molecule-based gene vectors have been...
Sat Mar 07, 2020 02:00
Pharmaceutics, Vol. 12, Pages 238: Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO) Pharmaceutics doi: 10.3390/pharmaceutics12030238 Authors: Maria Lazaridou Evi Christodoulou Maria Nerantzaki Margaritis Kostoglou Dimitra A. Lambropoulou Angeliki Katsarou Kostas Pantopoulos Dimitrios N. Bikiaris The objective of this study was to develop chitosan (CS) nanoparticles (NPs) loaded with deferoxamine...
Sat Mar 07, 2020 02:00
Pharmaceutics, Vol. 12, Pages 237: A Rational Design of a Biphasic DissolutionSetup—Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion Pharmaceutics doi: 10.3390/pharmaceutics12030237 Authors: Denninger Westedt Rosenberg Wagner Biphasic dissolution systems achieved good predictability for the in vivo performance of several formulations of poorly water-soluble drugs by characterizing dissolution, precipitation, re-dissolution, and...
Fri Mar 06, 2020 02:00
Pharmaceutics, Vol. 12, Pages 236: Patients’ Preferences and Willingness to Pay for Solid Forms of Oral Medications—Results of the Discrete Choice Experiment in Polish Outpatients Pharmaceutics doi: 10.3390/pharmaceutics12030236 Authors: Kurczewska-Michalak Kardas Czajkowski Purpose: Personal preferences play an important role in the patients’ decision process whether to adhere to treatment, or not. The purpose of this study is to assess Polish outpatients’...
Fri Mar 06, 2020 02:00
Pharmacy, Vol. 8, Pages 32: Precision Genomic Practice in Oncology: Pharmacist Role and Experience in an Ambulatory Care Clinic Pharmacy doi: 10.3390/pharmacy8010032 Authors: Farah Raheem Pauline Kim Meagan Grove Patrick J. Kiel Recent advancements in molecular testing, the availability of cost-effective technology, and novel approaches to clinical trial design have facilitated the implementation of tumor genome sequencing into standard of care oncology practices. Current models...
Sun Mar 08, 2020 02:00
Plants, Vol. 9, Pages 342: Genome-Wide Identification and Expression Analysis of Sugar Transporter (ST) Gene Family in Longan (Dimocarpus longan L.) Plants doi: 10.3390/plants9030342 Authors: Ting Fang Yuan Peng Ya Rao Shenghao Li Lihui Zeng Carbohydrates are nutrients and important signal molecules in higher plants. Sugar transporters (ST) play important role not only in long-distance transport of sugar, but also in sugar accumulations in sink cells. Longan (Dimocarpus longan...
Sun Mar 08, 2020 02:00
Plants, Vol. 9, Pages 341: Foliar Pre-Treatment with Abscisic Acid Enhances Olive Tree Drought Adaptability Plants doi: 10.3390/plants9030341 Authors: Cátia Brito Lia-Tânia Dinis Helena Ferreira José Moutinho-Pereira Carlos M. Correia Water is the most widely limiting factor for plants distribution, survival and agricultural productivity, their responses to drought and recovery being critical for their success and productivity. Olea europaea L. is a well-adapted species to...
Sun Mar 08, 2020 02:00
Plants, Vol. 9, Pages 340: The Role of Proteases in Determining Stomatal Development and Tuning Pore Aperture: A Review Plants doi: 10.3390/plants9030340 Authors: Dimitrios Fanourakis Nikolaos Nikoloudakis Polyxeni Pappi Emmanouil Markakis Georgios Doupis Spyridoula N. Charova Costas Delis Georgios Tsaniklidis Plant proteases, the proteolytic enzymes that catalyze protein breakdown and recycling, play an essential role in a variety of biological processes including...
Sun Mar 08, 2020 02:00
Plants, Vol. 9, Pages 339: The Influence of New and Artificial Aged Microplastic and Leachates on the Germination of Lepidium sativum L Plants doi: 10.3390/plants9030339 Authors: Stephan Pflugmacher Amalia Sulek Hannah Mader Jeongin Heo Ji Hyeon Noh Olli-Pekka Penttinen YoungJun Kim Sanghun Kim Maranda Esterhuizen With the increase in environmental monitoring and assessing, we are gaining insight into the extent of microplastic pollution in our environment. The...
Sat Mar 07, 2020 02:00
Plants, Vol. 9, Pages 338: Genetic Diversity and Population Structure of Rhododendron rex Subsp. rex Inferred from Microsatellite Markers and Chloroplast DNA Sequences Plants doi: 10.3390/plants9030338 Authors: Zhang Liu Wang Shen Genetic diversity is vital to the sustainable utilization and conservation of plant species. Rhododendron rex subsp. rex Lévl. is an endangered species endemic to the southwest of China. Although the natural populations of this species...
Sat Mar 07, 2020 02:00
Plants, Vol. 9, Pages 337: Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts Plants doi: 10.3390/plants9030337 Authors: Vujić Vidaković Jadranin Novaković Trifunović Tešević Mandić Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant...
Fri Mar 06, 2020 02:00
Plants, Vol. 9, Pages 336: Genome-Wide Identification and Expression Profile Analysis of the NF-Y Transcription Factor Gene Family in Petunia hybrida Plants doi: 10.3390/plants9030336 Authors: Qian Wei Shiyun Wen Chuying Lan Yixun Yu Guoju Chen Nuclear Factor Ys (NF-Ys) are a class of heterotrimeric transcription factors that play key roles in many biological processes, such as abiotic stress responses, flowering time, and root development. The petunia (Petunia hybrida) is...
Fri Mar 06, 2020 02:00
Plants, Vol. 9, Pages 335: Heat Stress Factors Expressed during Seed Maturation Differentially Regulate Seed Longevity and Seedling Greening Plants doi: 10.3390/plants9030335 Authors: Concepción Almoguera Pilar Prieto-Dapena Raúl Carranco José Luis Ruiz Juan Jordano Heat Stress Factor A9 (A9), a seed-specific transcription factor contributing to seed longevity, also enhances phytochrome-dependent seedling greening. The RNA-seq analyses of imbibed-seed transcripts here reported...
Fri Mar 06, 2020 02:00
Religions, Vol. 11, Pages 114: Luminous Bodies, Playful Children, and Abusive Grandmothers: Trauma, Dissociation, and Disorganized Attachment in the Early History of Great Perfection (rDzogs Chen) Buddhism Religions doi: 10.3390/rel11030114 Authors: Geisshuesler This contribution explores the development of the highest teachings of the “Old School” (rnying ma) of Tibetan Buddhism, known as the Great Perfection (rdzogs chen). Between the tenth and the twelfth centuries,...
Sat Mar 07, 2020 02:00
Religions, Vol. 11, Pages 113: A Time for Hope in Dark Times Religions doi: 10.3390/rel11030113 Authors: Giroux Filippakou This article explores the political importance of embracing a notion of hope in a time of growing authoritarianism across the globe. It defines hope as the ability to both mobilize what might be called a democratic imaginary and a notion of hope rooted in a realistic assessment of what it means to engage in forms of struggle for economic and social justice,...
Fri Mar 06, 2020 02:00
Religions, Vol. 11, Pages 112: Cain and Abel: Re-Imagining the Immigration ‘Crisis’ Religions doi: 10.3390/rel11030112 Authors: Abi Doukhan This essay proposes to interpret the significance of the so-called immigration crisis in the light of the ancient story of Cain and Abel. Much more than a mere conflict between brothers, this essay will argue that the story of Cain and Abel presents two archetypal ways of dwelling in the world: the sedentary and the nomadic. As such, the story sheds...
Fri Mar 06, 2020 02:00
Resources, Vol. 9, Pages 26: Water Recovery from Floor Cleaning Operations of Industrial or Public Areas: The Results of a Field Test Resources doi: 10.3390/resources9030026 Authors: Ruffino Water resources are increasingly under pressure because of human activities and economic development. Moreover, accelerated urbanization and the expansion of drinking water supply and sanitation systems contribute to this rising demand. The development of water reuse solutions is an urgent issue....
Fri Mar 06, 2020 02:00
Resources, Vol. 9, Pages 25: Erratum: Mohr et al. Global Projection of Lead-Zinc Supply from Known Resources. Resources, 2018, 7, 17 Resources doi: 10.3390/resources9030025 Authors: Steve Mohr Damien Giurco Monique Retamal Leah Mason Gavin Mudd The authors wish to make the following correction to this paper [...]
Fri Mar 06, 2020 02:00
Robotics, Vol. 9, Pages 11: Towards Tethered Tool Manipulation Planning with the Help of a Tool Balancer Robotics doi: 10.3390/robotics9010011 Authors: Daniel Sanchez Weiwei Wan Kensuke Harada Handling and maneuvering tools across a robot workspace is a challenging task that often requires the implementation of constrained motion planning. In the case of wired or tethered tools, their maneuvering becomes considerably harder by the tool cable. If the cable presence is not considered,...
Fri Mar 06, 2020 02:00
Sci. Pharm., Vol. 88, Pages 11: Cytotoxicity of Standardized Curcuminoids Mixture against Epithelial Ovarian Cancer Cell Line SKOV-3 Scientia Pharmaceutica doi: 10.3390/scipharm88010011 Authors: Heba Almosa Mihal Alqriqri Iuliana Denetiu Mohammed A. Baghdadi Mohammed Alkhaled Mahmoud Alhosin Wejdan A. Aldajani Mazin Zamzami Mehmet H. Ucisik Samar Damiati Herbal medicine has been in use for centuries for a wide variety of ailments; however, the efficacy of its...
Sat Mar 07, 2020 02:00
Sports, Vol. 8, Pages 30: Physical Fitness after Anterior Cruciate Ligament Reconstruction: Influence of Graft, Age, and Sex Sports doi: 10.3390/sports8030030 Authors: Robert Csapo Helmut Pointner Christian Hoser Peter Gföller Christian Raschner Christian Fink Functional tests are used to facilitate return-to-sports decisions after anterior cruciate ligament reconstruction (ACLR). This study presents comprehensive physical fitness test data acquired in highly active patients...
Fri Mar 06, 2020 02:00
Technologies, Vol. 8, Pages 16: A New Simplified Model and Parameter Estimations for a HfO2-Based Memristor † Technologies doi: 10.3390/technologies8010016 Authors: Valeri Mladenov The purpose of this paper was to propose a complete analysis and parameter estimations of a new simplified and highly nonlinear hafnium dioxide memristor model that is appropriate for high-frequency signals. For the simulations; a nonlinear window function previously offered by the author together with a highly...
Sat Mar 07, 2020 02:00
Toxins, Vol. 12, Pages 165: Microcystin-LR Does Not Alter Cell Survival and Intracellular Signaling in Human Bronchial Epithelial Cells Toxins doi: 10.3390/toxins12030165 Authors: Ondřej Brózman Barbara Kubickova Pavel Babica Petra Laboha Changes in ecological and environmental factors lead to an increased occurrence of cyanobacterial water blooms, while secondary metabolites-producing cyanobacteria pose a threat to both environmental and human health. Apart from oral and dermal...
Sat Mar 07, 2020 02:00
Toxins, Vol. 12, Pages 164: Forty Years of the Description of Brown Spider Venom Phospholipases-D Toxins doi: 10.3390/toxins12030164 Authors: Luiza Helena Gremski Hanna Câmara da Justa Thaís Pereira da Silva Nayanne Louise Costacurta Polli Bruno César Antunes João Carlos Minozzo Ana Carolina Martins Wille Andrea Senff-Ribeiro Raghuvir Krishnaswamy Arni Silvio Sanches Veiga Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a serious...
Fri Mar 06, 2020 02:00
TropicalMed, Vol. 5, Pages 40: Purified Vero Cell Rabies Vaccine (PVRV, Verorab®): A Systematic Review of Intradermal Use Between 1985 and 2019 Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5010040 Authors: Thomas Moulenat Céline Petit Valérie Bosch Castells Guy Houillon The purified Vero cell rabies vaccine (PVRV; Verorab®, Sanofi Pasteur) has been used in rabies prevention since 1985. Evolving rabies vaccination trends, including shorter intradermal...
Sat Mar 07, 2020 02:00
TropicalMed, Vol. 5, Pages 39: Gnathostomiasis Acquired by Visitors to the Okavango Delta, Botswana Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5010039 Authors: John Frean Gnathostomiasis is a zoonotic nematode parasite disease, most commonly acquired by eating raw or undercooked fish. Although the disease is well known in parts of Asia and Central and South America, relatively few cases have been reported from Africa. Raw fish consumed in the Okavango River delta...
Fri Mar 06, 2020 02:00
Veterinary Sciences, Vol. 7, Pages 31: Antimicrobial Activity of a Phage Mixture and a Lactic Acid Bacterium against Staphylococcus aureus from Bovine Mastitis Veterinary Sciences doi: 10.3390/vetsci7010031 Authors: Isabel Titze Volker Krömker The antimicrobial activity of a phage mixture and a lactic acid bacterium against Staphylococcus aureus isolates from bovine origin was investigated in vitro with regard to possible applications in the therapy of udder inflammation (mastitis)...
Fri Mar 06, 2020 02:00
Viruses, Vol. 12, Pages 295: Topology, Antiviral Functional Residues and Mechanism of IFITM1 Viruses doi: 10.3390/v12030295 Authors: Fang Sun Zhiqiang Xia Yuewen Han Minjun Gao Luyao Wang Yingliang Wu Jean-Marc Sabatier Lixia Miao Zhijian Cao Interferon-inducible transmembrane proteins (IFITM1/2/3) have been reported to suppress the entry of a wide range of viruses. However, their antiviral functional residues and specific mechanisms are still unclear. Here, we...
Sun Mar 08, 2020 02:00
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