Viruses, Vol. 12, Pages 331: Phylogenetic and Demographic Characterization of Directed HIV-1 Transmission Using Deep Sequences from High-Risk and General Population Cohorts/Groups in Uganda Viruses doi: 10.3390/v12030331 Authors: Nicholas Bbosa Deogratius Ssemwanga Alfred Ssekagiri Xiaoyue Xi Yunia Mayanja Ubaldo Bahemuka Janet Seeley Deenan Pillay Lucie Abeler-Dörner Tanya Golubchik Christophe Fraser Pontiano Kaleebu Oliver Ratmann Across sub-Saharan...
Viruses, Vol. 12, Pages 330: CRISPR-Cas9 Dual-gRNA Attack Causes Mutation, Excision and Inversion of the HIV-1 Proviral DNA Viruses doi: 10.3390/v12030330 Authors: Caroline S. Binda Bep Klaver Ben Berkhout Atze T. Das Although several studies demonstrated that the HIV proviral DNA can be effectively targeted and inactivated by the CRISPR-Cas9 system, the precise inactivation mechanism has not yet been analyzed. Whereas some studies suggested efficient proviral DNA excision upon...
Viruses, Vol. 12, Pages 329: Pervasive Differential Splicing in Marek’s Disease Virus can Discriminate CVI-988 Vaccine Strain from RB-1B Very Virulent Strain in Chicken Embryonic Fibroblasts Viruses doi: 10.3390/v12030329 Authors: Yashar Sadigh Abdessamad Tahiri-Alaoui Stephen Spatz Venugopal Nair Paolo Ribeca Marek’s disease is a major scourge challenging poultry health worldwide. It is caused by the highly contagious Marek’s disease virus (MDV), an alphaherpesvirus....
Viruses, Vol. 12, Pages 328: PERK-Mediated Unfolded Protein Response Signaling Restricts Replication of the Tick-Borne Flavivirus Langat Virus Viruses doi: 10.3390/v12030328 Authors: Tyler G. Lewy Danielle K. Offerdahl Jeffrey M. Grabowski Eliza Kellman Luwanika Mlera Abhilash Chiramel Marshall E. Bloom The unfolded protein response (UPR) maintains protein-folding homeostasis in the endoplasmic reticulum (ER) and has been implicated as both beneficial and detrimental...
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Water, Vol. 12, Pages 857: Developing a Modified Umbrella Index for Conservation of Macroinvertebrate Diversity in Taizi River Basin, China Water doi: 10.3390/w12030857 Authors: Xin Gao Hai-yu Ding Rui Xia Hui Wang Qian-qian Kou Sen Ding Conservation strategies for a reliable set of umbrella species should benefit many co-occurring species and will improve conservation efficiency. The umbrella index (UI) is increasingly applied for umbrella species selection in different...
Water, Vol. 12, Pages 853: Recharge–Discharge Relations of Groundwater in Volcanic Terrain of Semi-Humid Tropical Highlands of Ethiopia: The Case of Infranz Springs, in the Upper Blue Nile Water doi: 10.3390/w12030853 Authors: Fenta Nigate Marc Van Camp Alemu Yenehun Ashebir Sewale Belay Kristine Walraevens The major springs in the Infranz catchment are a significant source of water for Bahir Dar City and nearby villages, while sustaining the Infranz River and the downstream...
Water, Vol. 12, Pages 855: Design of PI Controllers for Irrigation Canals Based on Linear Matrix Inequalities Water doi: 10.3390/w12030855 Authors: Teresa Arauz José M. Maestre Xin Tian Guanghua Guan A new Proportional-Integral (PI) tuning method based on Linear Matrix Inequalities (LMIs) is presented. In particular, an LMI-based optimal control problem is solved to obtain a sparse feedback that provides the PI tuning. The ASCE Test Canal 1 is used as a case study. Using a linearised...
Water, Vol. 12, Pages 854: Evaluation of Dispersed Alkaline Substrate and Diffusive Exchange System Technologies for the Passive Treatment of Copper Mining Acid Drainage Water doi: 10.3390/w12030854 Authors: Alex Schwarz Iván Nancucheo Maria A. Gaete Diego Muñoz Pamela Sanhueza Martin Torregrosa Tobias Rötting Gordon Southam Marcelo Aybar The study evaluates the performance of the novel ADES (alkaline diffusive exchange System), SDES (sulfidogenic diffusive exchange...
Water, Vol. 12, Pages 856: CFD Modeling of Effluent Discharges: A Review of Past Numerical Studies Water doi: 10.3390/w12030856 Authors: Abdolmajid Mohammadian Hossein Kheirkhah Gildeh Ioan Nistor Effluent discharge mixing and dispersion have been studied for many decades. Studies began with experimental investigations of geometrical and concentration characteristics of the jets in the near-field zone. More robust experiments were performed using Laser-Induced Fluorescence (LIF)...
Water, Vol. 12, Pages 851: Limnological Quality: Seasonality Assessment and Potential for Contamination of the Pindaré River Watershed, Pre-Amazon Region, Brazil Water doi: 10.3390/w12030851 Authors: Jamilly N. Muniz Klinger G. Duarte Fábio H. Ramos Braga Neuriane S. Lima Darlan F. Silva Wellyson C. A. Firmo Márcia R. V. Batista Flor M. A. M. Silva Rita de C. M. Miranda Maria Raimunda C. Silva Watersheds are defined as a set of lands where water drainage occurs...
Water, Vol. 12, Pages 852: Evaluating the Impact of Climate Change on Paddy Water Balance Using APEX-Paddy Model Water doi: 10.3390/w12030852 Authors: Mohammad Kamruzzaman Syewoon Hwang Soon-Kun Choi Jaepil Cho Inhong Song Jung-hun Song Hanseok Jeong Taeil Jang Seung-Hwan Yoo This research aims to assess the impact of climate change on water balance components in irrigated paddy cultivation. The APEX-Paddy model, which is the modified version of the APEX (Agricultural...
Water, Vol. 12, Pages 850: Impact of Combined Sewer Systems on the Quality of Urban Streams: Frequency and Duration of Elevated Micropollutant Concentrations Water doi: 10.3390/w12030850 Authors: Dittmer Bachmann-Machnik Launay Water quality in urban streams is highly influenced by emissions from WWTP and from sewer systems particularly by overflows from combined systems. During storm events, this causes random fluctuations in discharge and pollutant concentrations over a wide...
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