Antibiotics, Vol. 9, Pages 145: Rifaximin Alleviates Endotoxemia with Decreased Serum Levels of Soluble CD163 and Mannose Receptor and Partial Modification of Gut Microbiota in Cirrhotic Patients Antibiotics doi: 10.3390/antibiotics9040145 Authors: Kaji Saikawa Takaya Fujinaga Furukawa Kitagawa Ozutsumi Kaya Tsuji Sawada Kawaratani Moriya Namisaki Akahane Mitoro Yoshiji Rifaximin is a poorly absorbable antibiotic against hepatic...
Antibiotics, Vol. 9, Pages 144: The Iron-chelator, N,N’-bis (2-hydroxybenzyl) Ethylenediamine-N,N’-Diacetic acid is an Effective Colistin Adjunct against Clinical Strains of Biofilm-Dwelling Pseudomonas aeruginosa Antibiotics doi: 10.3390/antibiotics9040144 Authors: Mettrick Hassan Lamont Reid Targeting the iron requirement of Pseudomonas aeruginosa may be an effective adjunctive for conventional antibiotic treatment against biofilm-dwelling P. aeruginosa. We, therefore,...
Antibiotics, Vol. 9, Pages 143: Excretion of the Polymyxin Derivative NAB739 in Murine Urine Antibiotics doi: 10.3390/antibiotics9040143 Authors: Martti Vaara Timo Vaara Janis Kuka Eduards Sevostjanovs Solveiga Grinberga Maija Dambrova Edgars Liepinsh Extremely multiresistant strains of Enterobacteriaceae are emerging and spreading at a worrisome pace. Polymyxins are used as the last-resort therapy against such strains, in spite of their nephrotoxicity. We have previously...
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Antioxidants, Vol. 9, Pages 287: Reactive Oxygen Species and Male Fertility Antioxidants doi: 10.3390/antiox9040287 Authors: O’Flaherty Human infertility affects ~15% of couples worldwide, and it is now recognized that in half of these cases, the causes of infertility can be traced to men[...]
Antioxidants, Vol. 9, Pages 286: Antioxidants Properties of Natural Products: A Themed Issue in Honor of Professor Isabel C.F.R. Ferreira Antioxidants doi: 10.3390/antiox9040286 Authors: Lillian Barros Professor Isabel C [...]
Antioxidants, Vol. 9, Pages 285: Cyanidin Chloride Induces Apoptosis by Inhibiting NF-κB Signaling through Activation of Nrf2 in Colorectal Cancer Cells Antioxidants doi: 10.3390/antiox9040285 Authors: Da-Young Lee Sun-Mi Yun Moon-Young Song Kiwon Jung Eun-Hee Kim Colorectal cancer (CRC) is the third most common cancer worldwide and a leading cause of cancer-related deaths in developed countries. Anthocyanins are a class of flavonoids, widely distributed in food, exhibiting...
Antioxidants, Vol. 9, Pages 283: Multi-Component Antioxidative System and Robust Carbohydrate Status, the Essence of Plant Arsenic Tolerance Antioxidants doi: 10.3390/antiox9040283 Authors: Kofroňová Hrdinová Mašková Tremlová Soudek Petrová Pinkas Lipavská Arsenic (As) contaminates the food chain and decreases agricultural production through impairing plants, particularly due to oxidative stress. To better understand the As tolerance mechanisms, two contrasting...
Antioxidants, Vol. 9, Pages 284: Effects of Trichoderma Biostimulation on the Phenolic Profile of Extra-Virgin Olive Oil and Olive Oil By-Products Antioxidants doi: 10.3390/antiox9040284 Authors: Dini Graziani Fedele Sicari Vinale Castaldo Ritieni Olive trees are grown on five continents. Fertilization of fields, pest control management, olive leaves, olive pomaces, and olive mill wastewaters have a substantial environmental impact. It is possible to reduce this...
Antioxidants, Vol. 9, Pages 282: Bioactive Variability and In Vitro and In Vivo Antioxidant Activity of Unprocessed and Processed Flour of Nine Cultivars of Australian lupin Species: A Comprehensive Substantiation Antioxidants doi: 10.3390/antiox9040282 Authors: Kishor Mazumder Afia Nabila Asma Aktar Asgar Farahnaky The aim of this present investigation was to analyze bioactive compounds, as well as demonstrate the antioxidant activities of nine cultivars of Australian lupin...
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Arts, Vol. 9, Pages 44: Rosas, the Storyless, and Roles Arts doi: 10.3390/arts9020044 Authors: Haidu Analyzing the early work of Anne Teresa De Keersmaeker—and particularly Rosas danst Rosas (1983)—this article examines the notion of “the storyless” in relation to the role: that pillar of dance, and especially choreography, which enables the individuation, transmission, and exchange of each dancer’s part. Set in relation to the principles...
Arts, Vol. 9, Pages 43: Trisha Brown: Between Abstraction and Representation (1966–1998) Arts doi: 10.3390/arts9020043 Authors: Rosenberg Choreographer Trisha Brown (1936–2017) is renowned as one of the most influential abstract artists of the twentieth and twenty-first centuries. Emerging from Judson Dance Theater and the 1960s avant-garde, Brown invented what she termed her ‘pure movement’ abstract vocabulary in the 1970s, rejecting narrative, psychology...
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Atmosphere, Vol. 11, Pages 333: Large Sample Comparison of Parameter Estimates in Gamma Raindrop Distributions Atmosphere doi: 10.3390/atmos11040333 Authors: Johnson Kliche Raindrop size distributions have been characterized through the gamma family. Over the years, quite a few estimates of these gamma parameters have been proposed. The natural question for the practitioner, then, is what estimation procedure should be used. We provide guidance in answering this question when a...
Atmosphere, Vol. 11, Pages 331: Numerical Sensitivity Tests of Volatile Organic Compounds Emission to PM2.5 Formation during Heat Wave Period in 2018 in Two Southeast Korean Cities Atmosphere doi: 10.3390/atmos11040331 Authors: Geum-Hee Yang Yu-Jin Jo Hyo-Jung Lee Chang-Keun Song Cheol-Hee Kim A record-breaking severe heat wave was recorded in southeast Korea from 11 July to 15 August 2018, and the numerical sensitivity simulations of volatile organic compound (VOC) to secondarily...
Atmosphere, Vol. 11, Pages 332: Innovative Trend Analysis of Precipitation in the Lake Issyk-Kul Basin, Kyrgyzstan Atmosphere doi: 10.3390/atmos11040332 Authors: Alifujiang Abuduwaili Maihemuti Emin Groll The analysis of various characteristics and trends of precipitation is an essential task to improve the utilization of water resources. Lake Issyk-Kul basin is an upper alpine catchment, which is more susceptible to the effects of climate variability, and identifying...
Atmosphere, Vol. 11, Pages 330: Source Apportionment of Fine Organic and Inorganic Atmospheric Aerosol in an Urban Background Area in Greece Atmosphere doi: 10.3390/atmos11040330 Authors: Manousos Ioannis Manousakas Kalliopi Florou Spyros N. Pandis Fine particulate matter (PM) originates from various emission sources and physicochemical processes. Quantification of the sources of PM is an important step during the planning of efficient mitigation strategies and the investigation...
Atmosphere, Vol. 11, Pages 328: Effects of Rear Angle on the Turbulent Wake Flow between Two in-Line Ahmed Bodies Atmosphere doi: 10.3390/atmos11040328 Authors: Essel Das Balachandar Understanding the wake characteristics between two in-line vehicles is essential for improving and developing new strategies for reducing in-cabin air pollution. In this study, Ahmed bodies are used to investigate the effects of the rear slant angle of a leading vehicle on the mean flow and turbulent...
Atmosphere, Vol. 11, Pages 329: Greener and Leaner: Lower Energy and Water Consumption, and Reduced Work Orders, in Newly Constructed Boston Public Housing Atmosphere doi: 10.3390/atmos11040329 Authors: Michael Brod José Guillermo Cedeño Laurent John Kane Meryl D. Colton Charlotte Gabel Gary Adamkiewicz The Boston Residential Investigation on Green and Healthy Transitions (BRIGHT) Study is focused on quantifying the effects of redeveloping public housing developments into...
Atmosphere, Vol. 11, Pages 327: Impact of Air–Wave–Sea Coupling on the Simulation of Offshore Wind and Wave Energy Potentials Atmosphere doi: 10.3390/atmos11040327 Authors: Lichuan Wu Mingming Shao Erik Sahlée Offshore wind and wave energy potentials are commonly simulated by atmosphere and wave stand-alone models, in which the Atmosphere–Wave–Ocean (AWO) dynamical coupling processes are neglected. Based on four experiments (simulated by UU-CM, Uppsala University-Coupled...
Atmosphere, Vol. 11, Pages 325: Comparison of Remote Sensing based Multi-Source ET Models over Cropland in a Semi-Humid Region of China Atmosphere doi: 10.3390/atmos11040325 Authors: Zhuang Wang Xu The estimation of cropland evapotranspiration (ET) is essential for agriculture water management, drought monitoring, and yield forecast. Remote sensing-based multi-source ET models have been widely applied and validated in the semi-arid region of China. However, careful investigation...
Atmosphere, Vol. 11, Pages 326: Consumption of Hydrocarbons and Its Relationship with Ozone Formation in Two Chinese Megacities Atmosphere doi: 10.3390/atmos11040326 Authors: Chang Yak Wang Continuous measurements of ozone and its precursors were performed at sites in two Chinese megacities, i.e., an urban site in Beijing and a suburban site in the Pearl River Delta (PRD). At both sites, the total oxidants (O3 + NO2) varied with the ratio of ethylbenzene to m,p-xylenes, which...
Atmosphere, Vol. 11, Pages 324: Advanced Ultraviolet Radiation and Ozone Retrieval for Applications—Surface Ultraviolet Radiation Products Atmosphere doi: 10.3390/atmos11040324 Authors: Antti Lipponen Simone Ceccherini Ugo Cortesi Marco Gai Arno Keppens Andrea Masini Emilio Simeone Cecilia Tirelli Antti Arola AURORA (Advanced Ultraviolet Radiation and Ozone Retrieval for Applications) is a three-year project supported by the European Union in the frame of its...
Atmosphere, Vol. 11, Pages 323: Aircraft Emission Inventory and Characteristics of the Airport Cluster in the Guangdong–Hong Kong–Macao Greater Bay Area, China Atmosphere doi: 10.3390/atmos11040323 Authors: Jie Li Haotian Yang Xingang Liu Nu Yu Yong Tian Xiaoning Zhou Peng Zhang Kai Wang In this study, a compound method using modified Boeing Fuel Flow Method 2 (BFFM2) and an updated First Order Approximation V3.0 (FOA3.0) method deploying the ICAO Time-in-Mode (TIM)...
Atmosphere, Vol. 11, Pages 322: Aerosol Optical Properties and Contribution to Differentiate Haze and Haze-Free Weather in Wuhan City Atmosphere doi: 10.3390/atmos11040322 Authors: Zhang Liu Bilal Zhang Nazeer Atique Han Gong Haze is an atmospheric phenomenon in which different types of particulates obscure the sky, and hence affect almost all human activities. Over a couple of recent decades, China has witnessed increasingly worse air quality as well as...
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Beverages, Vol. 6, Pages 20: The Inoculation of Probiotics In Vivo Is a Challenge: Strategies to Improve Their Survival, to Avoid Unpleasant Changes, or to Enhance Their Performances in Beverages Beverages doi: 10.3390/beverages6020020 Authors: Barbara Speranza Daniela Campaniello Leonardo Petruzzi Clelia Altieri Milena Sinigaglia Antonio Bevilacqua Maria Rosaria Corbo The inoculation of probiotics in beverages (probiotication) requires special technologies, as probiotic...
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Bioengineering, Vol. 7, Pages 31: Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products Bioengineering doi: 10.3390/bioengineering7020031 Authors: Brian Lee Breanna S. Borys Michael S. Kallos Carlos A. V. Rodrigues Teresa P. Silva Joaquim M. S. Cabral Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of diseases and vast...
Bioengineering, Vol. 7, Pages 30: 3D Printing of Gelled and Cross-Linked Cellulose Solutions, an Exploration of Printing Parameters and Gel Behaviour Bioengineering doi: 10.3390/bioengineering7020030 Authors: Huber Najaf Zadeh Feast Roughan Fee In recent years, 3D printing has enabled the fabrication of complex designs, with low-cost customization and an ever-increasing range of materials. Yet, these abilities have also created an enormous challenge in optimizing a large...
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Biology, Vol. 9, Pages 64: Phylogenetic Analyses of Sites in Different Protein Structural Environments Result in Distinct Placements of the Metazoan Root Biology doi: 10.3390/biology9040064 Authors: Pandey Braun Phylogenomics, the use of large datasets to examine phylogeny, has revolutionized the study of evolutionary relationships. However, genome-scale data have not been able to resolve all relationships in the tree of life; this could reflect, at least in part, the poor-fit of...
Biology, Vol. 9, Pages 63: Contribution of Neurotrophins to the Immune System Regulation and Possible Connection to Alcohol Addiction Biology doi: 10.3390/biology9040063 Authors: Evgenii M. Kozlov Andrey V. Grechko Yegor S. Chegodaev Wei-Kai Wu Alexander N. Orekhov The first references to neurotrophic factors date back to the middle of the 20th century when the nerve growth factor (NGF) was first discovered. Later studies delivered a large amount of data on neurotrophic factors....
Biology, Vol. 9, Pages 62: A Review of Candidate Genes and Pathways in Preeclampsia–An Integrated Bioinformatical Analysis Biology doi: 10.3390/biology9040062 Authors: Mohamad Mohd Manzor Zulkifli Zainal Hayati Ahmad Asnawi : Preeclampsia is a pregnancy-specific disorder characterized by the presence of hypertension with the onset of either proteinuria, maternal organ or uteroplacental dysfunction. Preeclampsia is one of the leading causes of maternal and fetal mortality...
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Biomedicines, Vol. 8, Pages 72: Immunosuppression with Calcineurin Inhibitor after Renal Transplant Failure Inhibits Allosensitization Biomedicines doi: 10.3390/biomedicines8040072 Authors: Covadonga López del Moral Cuesta Sandra Guiral Foz David Gómez Pereda José Luis Pérez Canga Marina de Cos Gómez Jaime Mazón Ruiz Ana García Santiago José Iñigo Romón Alonso Rosalía Valero San Cecilio Emilio Rodrigo Calabia David San Segundo Arribas Marcos López Hoyos Juan...
Biomedicines, Vol. 8, Pages 71: Current Advances in Pediatric Onset Multiple Sclerosis Biomedicines doi: 10.3390/biomedicines8040071 Authors: Kristen S. Fisher Fernando X. Cuascut Victor M. Rivera George J. Hutton Multiple sclerosis (MS) is an autoimmune inflammatory disease affecting the central nervous system leading to demyelination. MS in the pediatric population is rare, but has been shown to lead to significant disability over the duration of the disease. As we have learned...
Biomedicines, Vol. 8, Pages 70: The Lymphoscintigraphic Study of Unpredictable Head and Neck Cutaneous Melanoma Lymphatic Drainage Biomedicines doi: 10.3390/biomedicines8040070 Authors: Lavelli Ferrari Santo Altini Ballini Sardaro Fanelli Pisani Nappi Giudice Rubini Head and neck cutaneous melanoma (HNCM) does not always follow standard lymphatic drainage; typical expected lymphatic pathways are associated with unexpected ones. The aim of this...
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Biomolecules, Vol. 10, Pages 519: Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors Biomolecules doi: 10.3390/biom10040519 Authors: Oddrun Elise Olsen Hanne Hella Samah Elsaadi Carsten Jacobi Erik Martinez-Hackert Toril Holien Activins belong to the transforming growth factor (TGF)-β family of multifunctional cytokines and signal via the activin receptors ALK4 or ALK7 to activate the SMAD2/3 pathway. In...
Biomolecules, Vol. 10, Pages 518: A Proof-of-Concept Fragment Screening of a Hit-Validated 96-Compounds Library against Human Carbonic Anhydrase II Biomolecules doi: 10.3390/biom10040518 Authors: Steffen Glöckner Andreas Heine Gerhard Klebe Fragment screening is a powerful tool to identify and characterize binding pockets in proteins. We herein present the results of a proof-of-concept screening campaign of a versatile 96-entry fragment library from our laboratory against the drug...
Biomolecules, Vol. 10, Pages 517: A High-Throughput Single-Clone Phage Fluorescence Microwell Immunoassay and Laser-Driven Clonal Retrieval System Biomolecules doi: 10.3390/biom10040517 Authors: Seohee Chang Soohyun Kim Jerome Han Suji Ha Hyunho Lee Seo Woo Song Daewon Lee Sunghoon Kwon Junho Chung Junhoi Kim Phage display is one of the most frequently used platform technologies utilized to screen and select therapeutic antibodies, and has contributed to the...
Biomolecules, Vol. 10, Pages 516: Evaluation of Pharmacological and Phytochemical Profiles Piptadeniastrum africanum (Hook.f.) Brenan Stem Bark Extracts Biomolecules doi: 10.3390/biom10040516 Authors: Sinan Chiavaroli Orlando Bene Zengin Cziáky Jekő Mahomoodally Picot-Allain Menghini Recinella Brunetti Leone Ciferri Di Simone Ferrante The stem bark (SB) of Piptadeniastrum africanum (PA) has been extensively used in African...
Biomolecules, Vol. 10, Pages 515: A Novel Serine Protease Inhibitor PE-BBI Ameliorates Cockroach Extract-Mediated Airway Epithelial Barrier Dysfunction Biomolecules doi: 10.3390/biom10040515 Authors: Reihill Ouyang Yang Douglas Zhou Chen Martin Epithelial barrier dysfunction, characteristic of allergic airway disease may be, at least in part, due to the action of allergen-associated protease activities. Cockroach allergy is a major global health issue, with cockroaches...
Biomolecules, Vol. 10, Pages 514: Glycofullerenes Inhibit Particulate Matter Induced Inflammation and Loss of Barrier Proteins in HaCaT Human Keratinocytes Biomolecules doi: 10.3390/biom10040514 Authors: Lee Su Chiang Lee Li Lee Hsu Yan Li Chen Peng Lai Exposure to particulate matter (PM) has been linked to pulmonary and cardiovascular dysfunctions, as well as skin diseases, etc. PM impairs the skin barrier functions and is also involved in...
Biomolecules, Vol. 10, Pages 513: A Novel NAD-RNA Decapping Pathway Discovered by Synthetic Light-Up NAD-RNAs Biomolecules doi: 10.3390/biom10040513 Authors: Florian Abele Katharina Höfer Patrick Bernhard Julia Grawenhoff Maximilian Seidel André Krause Sara Kopf Martin Schröter Andres Jäschke The complexity of the transcriptome is governed by the intricate interplay of transcription, RNA processing, translocation, and decay. In eukaryotes, the removal of the 5’-RNA...
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