Shift in worker physiology and gene expression pattern from reproductive to diapause-like with colony age in the bumble bee Bombus impatiens [NEW RESULTS]

Insects maximize their fitness by exhibiting predictable and adaptive seasonal patterns in response to changing environmental conditions. These seasonal patterns are often expressed even when insects are kept in captivity, suggesting they are functionally and evolutionary important. In this study we examined whether workers of the eusocial bumble bee Bombus impatiens maintained a seasonal signature when kept in captivity. We used an integrative approach and compared worker egg-laying, ovarian activation,...

bioRxiv Subject Collection: Evolutionary Biology

Wed Mar 18, 2020 02:00

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 Experimental and Clinical Endocrinology & Diabetes

HOMA-Adiponectin Closely Associates with Cardiometabolic Risk Markers in Middle-Aged Indians with Metabolic Syndrome

Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1120-8163 Background Unhealthy dietary habits and sedentary lifestyles have raised alarming concerns for the rising prevalence of metabolic syndrome (MetS) and associated cardiometabolic risk among Indians at an early age. Insulin resistance and adiposity are the important risk factors associated with MetS. The present study aimed to investigate the relationship between a modified marker of insulin resistance (homeostatic model assessment-adiponectin (HOMA-AD))...

Experimental and Clinical Endocrinology & Diabetes

Wed Mar 18, 2020 01:00

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 Latest Results for Medical

Discrimination and quantification of live/dead rat brain cells using a non-linear segmentation model

Abstract The automatic cell analysis method is capable of segmenting the cells and can detect the number of live/dead cells present in the body. This study proposed a novel non-linear segmentation model (NSM) for the segmentation and quantification of live/dead cells present in the body. This work also reveals the aspects of electromagnetic radiation on the cell body. The bright images of the hippocampal CA3 region of the rat brain under the resolution of 60 × objective are used...

Latest Results for Medical

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 Molecular Cancer Therapeutics Online First Articles

Type I IFN, Ly6C+ cells, and phagocytes support suppression of peritoneal carcinomatosis elicited by a TLR and CLR agonist combination

Metastatic cancer involving spread to the peritoneal cavity is referred to as peritoneal carcinomatosis and has a very poor prognosis. Our previous study demonstrated a toll-like receptor (TLR) and C-type lectin receptor (CLR) agonist pairing of monophosphoryl lipid A (MPL) and trehalose-6,6'-dicorynomycolate (TDCM) effectively inhibits tumor growth and ascites development following TA3-Ha and EL4 challenge through a mechanism dependent upon B-1a cell-produced natural IgM and complement. In the current...

Molecular Cancer Therapeutics Online First Articles

Wed Mar 18, 2020 14:17

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 World journal of radiology

Giant intraventricular and paraventricular cavernous malformations with multifocal subependymal cavernous malformations in pediatric patients: Two case reports.

Related ArticlesGiant intraventricular and paraventricular cavernous malformations with multifocal subependymal cavernous malformations in pediatric patients: Two case reports. World J Radiol. 2020 Feb 28;12(2):10-17 Authors: Eng-Chuan S, Kritsaneepaiboon S, Kaewborisutsakul A, Kanjanapradit K Abstract BACKGROUND: Giant cavernous malformation (GCM) is rarely found in intraventricular or paraventricular locations. CASE SUMMARY: We present two...

World journal of radiology

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 Most Recent Articles: BMC Evolutionary Biology

Complex patterns of reticulate evolution in opportunistic weeds (Potentilla L., Rosaceae), as revealed by low-copy nuclear markers

Most cinquefoils (Potentilla L., Rosaceae) are polyploids, ranging from tetraploid (4x) to dodecaploid (12x), diploids being a rare exception. Previous studies based on ribosomal and chloroplast data indicated th...

Most Recent Articles: BMC Evolutionary Biology

Wed Mar 18, 2020 02:00

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 Analytical Chemistry

[ASAP] Nanovolume Gas-Free Hydroxide Eluent Generator for Open Tubular Ion Chromatography

Analytical ChemistryDOI: 10.1021/acs.analchem.0c00505

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Design and Synthesis of a Ratiometric Photoacoustic Probe for In Situ Imaging of Zinc Ions in Deep Tissue In Vivo

Analytical ChemistryDOI: 10.1021/acs.analchem.9b05431

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Charge Distribution between Different Classes of Glycerophospolipids in MALDI-MS Imaging

Analytical ChemistryDOI: 10.1021/acs.analchem.9b05761

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Qualitative and Quantitative Distinction of <italic toggle="yes">ortho</italic>-, <italic toggle="yes">meta</italic>-, and <italic toggle="yes">para</italic>-Fluorotoluene by Means of Chirped Femtosecond Laser Ionization

Analytical ChemistryDOI: 10.1021/acs.analchem.0c00234

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Programmable DNA Tweezer-Actuated SERS Probe for the Sensitive Detection of AFB₁

Analytical ChemistryDOI: 10.1021/acs.analchem.9b04822

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Effect of Substrate Stiffness on Redox State of Single Cardiomyocyte: A Scanning Electrochemical Microscopy Study

Analytical ChemistryDOI: 10.1021/acs.analchem.9b03178

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Cleancap-Regulated Aggregation-Induced Emission Strategy for Highly Specific Analysis of Enzyme

Analytical ChemistryDOI: 10.1021/acs.analchem.0c00217

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Magneto-Mediated Electrochemical Sensor for Simultaneous Analysis of Breast Cancer Exosomal Proteins

Analytical ChemistryDOI: 10.1021/acs.analchem.0c00106

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Selection of Aptamers Against Vimentin for Isolation and Release of Circulating Tumor Cells Undergoing Epithelial Mesenchymal Transition

Analytical ChemistryDOI: 10.1021/acs.analchem.9b05690

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Validated Ultra-High-Performance Liquid Chromatography Hybrid High-Resolution Mass Spectrometry and Laser-Assisted Rapid Evaporative Ionization Mass Spectrometry for Salivary Metabolomics

Analytical ChemistryDOI: 10.1021/acs.analchem.9b05598

Analytical Chemistry

Wed Mar 18, 2020 06:00

[ASAP] Aptamer-Based Field-Effect Transistor for Detection of Avian Influenza Virus in Chicken Serum

Analytical ChemistryDOI: 10.1021/acs.analchem.0c00348

Analytical Chemistry

Wed Mar 18, 2020 06:00

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 Journal of the American Chemical Society: Latest Articles (ACS Publications)

[ASAP] Solid-State Nonlinear Optical Switch with the Widest Switching Temperature Range Owing to Its Continuously Tunable <italic toggle="yes">T</italic>_c

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c01741

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] Stoichiometric Formation of an Oxoiron(IV) Complex by a Soluble Methane Monooxygenase Type Activation of O₂ at an Iron(II)-Cyclam Center

Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b13756

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] Optical “Blinking” Triggered by Collisions of Single Supramolecular Assemblies of Amphiphilic Molecules with Interfaces of Liquid Crystals

Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b13360

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] Precise Molecular Design Toward Organic–Inorganic Zinc Chloride ABX₃ Ferroelectrics

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00315

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] How General Is Anomeric Retention during Collision-Induced Dissociation of Glycans?

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00264

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] Efficient Visible-Light-Driven CO₂ Reduction by a Cobalt Molecular Catalyst Covalently Linked to Mesoporous Carbon Nitride

Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b13930

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] Evidence of the Elusive Gold-Induced Non-classical Hydrogen Bonding in Aqueous Environments

Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b05493

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] A Deep Blue B,N-Doped Heptacene Emitter That Shows Both Thermally Activated Delayed Fluorescence and Delayed Fluorescence by Triplet–Triplet Annihilation

Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b13704

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] Palladium-Catalyzed Homocoupling of Highly Fluorinated Arylboronates: Studies of the Influence of Strongly vs Weakly Coordinating Solvents on the Reductive Elimination Process

Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b11871

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] Thermodynamics of Transition Metal Ion Binding to Proteins

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c01329

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] Unveiling the Relationship between the Perovskite Precursor Solution and the Resulting Device Performance

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00411

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

[ASAP] Spotlights on Recent <italic toggle="yes">JACS</italic> Publications

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02951

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Mar 18, 2020 06:00

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 Annals of Allergy, Asthma & Immunology

POEM correlates with EASI and other measures better than PO-SCORAD: A validation study

Little is known about the measurement properties of Patient-Oriented Scoring Atopic Dermatitis (PO-SCORAD) in adults with AD. Even less is known about how PO-SCORAD performs compared to the Patient-Oriented Eczema Measure (POEM).

Annals of Allergy, Asthma & Immunology

Wed Mar 18, 2020 02:00

Making the GRADE in Anaphylaxis Management: Towards Recommendations Integrating Values, Preferences, Context, and Shared Decision-Making

To review GRADE methodology and discuss the clinical application of conditional recommendations in clinical guidelines, specifically in the context of anaphylaxis.

Annals of Allergy, Asthma & Immunology

Wed Mar 18, 2020 02:00

Predictors of Severe Anaphylaxis In Hymenoptera Venom Allergy: The Importance of Absence of Urticaria/Angioedema

Hymenoptera venom allergy affects approximately 3% of the adult population in Western countries 1,2,3,4 and represents the most common cause of anaphylaxis in Germany, Austria and Switzerland accounting for 50% of reported cases5. The incidence of insect sting related mortality in Europe caused by anaphylaxis is estimated around 200 fatalities per year6, but the incidence of near-fatal episodes might be considerably higher7. Moreover, the documented mortality may be underestimated because of unrecognized...

Annals of Allergy, Asthma & Immunology

Wed Mar 18, 2020 02:00

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 BMC Evolutionary Biology - Latest Articles

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 Journal of Anatomy

Cervical ribs in human early life: morphological variability and first identification as a morbidity criterion in a past population

The first known archaeological collection of neonates and infants with cervical ribs allows us to investigate the morphological variability of this trait in early life, and its frequencies in a past population. Based on the results of biological and genetic literature, we show that this trait appears to be an indicator of morbidity in the sample. We propose a morphological classification that can be used to refine the analyses of the trait in future studies. Abstract Despite the medical literature...

Journal of Anatomy

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 American Journal of Medical Genetics Part A

Burn‐McKeown syndrome with biallelic promoter type 2 deletion in TXNL4A in two siblings

Abstract Burn‐McKeown syndrome (BMKS) (MIM# 608572) is a rare condition caused by biallelic variants in TXNL4A. BMKS is characterized by craniofacial dysmorphism, choanal atresia, and normal intellect in affected individuals. BMKS has overlapping clinical features with Treacher Collins syndrome. Till date, 15 families have been described with BMKS. Homozygosity or compound heterozygosity of promoter deletions and null variants in TXNL4A are known to cause most cases of BMKS. We describe the first...

American Journal of Medical Genetics Part A

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