Abstract Background Elevated systolic blood pressure (SBP) after successful revascularization via endovascular therapy (EVT) is a known predictor of poor outcome. However, the optimal SBP goal following EVT is still unknown. Objective To compare functional and safety outcomes between different SBP goals after EVT with successful revascularization (SR). Methods An international multicenter study that included 8 comprehensive stroke centers. Patients with anterior circulation...
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Virtual clinics have been proposed as a method of reducing costs and improving services in the National Health Service (NHS). The aim of this research was to assess the attitudes of clinicians and patients towards virtual consultations in a department of oral and maxillofacial surgery (OMFS). Patients and clinicians at conventional OMFS adult outpatient clinics were prospectively interviewed using a structured questionnaire. Variables recorded included type of consultation, overall attitude, time...
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Abstract Aortic pathologies such as aneurysm, dissection and trauma are relatively common and potentially fatal diseases. Over the past two decades, we have experienced unprecedented technical and medical developments in the field. Despite this, there is a great need, and great opportunities, to further explore the area. In this review, we have identified important areas that need to be further studied and selected priority aortic disease trials. There is a pressing need to update the...
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A wide range of sleep, psychiatric, and medical comorbidities can present with obstructive sleep apnea (OSA), complicating treatment because of intolerance or low adherence to traditional modalities of therapy. Providers must have heightened awareness of how these comorbidities can affect their patients’ OSA and work together as a team to optimize health and well-being in this complex population.
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Stereotact Funct Neurosurg 2020;98:72–72
Stereotact Funct Neurosurg 2020;98:71–71
Stereotact Funct Neurosurg 2020;98:70–70
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Abstract Objectives The cervical spine is the junction between the head and trunk, and it therefore facilitates head mobility and stability. The goal of this study is to test several predictions regarding cervical morphology and intervertebral ranges of motion. Materials and Methods Intervertebral ranges of motion for 12 primate species were collected via radiographs or taken from the literature. Morphometric data describing functionally relevant aspects of cervical vertebral morphology...
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Abstract Background Knowledge of pain modulation from orofacial somatosensory stimuli with different valence (pleasant‐unpleasant) is limited. Objectives To investigate: (1) The modulatory effects of painful, pleasant and unpleasant somatosensory stimuli on 2 models of experimental facial pain, (2) If modulation could be changed by blocking peripheral nerves via application of a local anesthetic: EMLA, or blocking endogenous opioid receptors via naltrexone, (3) If pain ratings were...
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Abstract Dihydromethysticin (DHM), a natural compound derived from Kava, has been reported to be effective against mental disorders and some malignant tumors. However, little is known about the inhibitory effect of DHM on colorectal cancer (CRC). First, we examined the impact of DHM on human colon cancer cell lines, which demonstrated that DHM inhibits proliferation, migration, and invasion and promotes apoptosis and cell cycle arrest in colon cancer cells in vitro. Using small hairpin RNA, we...
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