Pediatric Research, Published online: 02 March 2020; doi:10.1038/s41390-020-0828-3Utility of volatile organic compounds as a diagnostic tool in preterm infants
Pediatric Research, Published online: 02 March 2020; doi:10.1038/s41390-020-0827-4Continuous glucose monitoring profile during therapeutic hypothermia in encephalopathic infants with unfavorable outcome
Pediatric Research, Published online: 02 March 2020; doi:10.1038/s41390-020-0818-5Moderators in a physical activity intervention for adolescent girls
Pediatric Research, Published online: 02 March 2020; doi:10.1038/s41390-020-0816-7Derivation of a metabolic signature associated with bacterial meningitis in infants
Pediatric Research, Published online: 02 March 2020; doi:10.1038/s41390-020-0812-yEvaluation of inflammatory bowel disease activity in children using serum trefoil factor peptide
Pediatric Research, Published online: 02 March 2020; doi:10.1038/s41390-020-0814-9Electrocardiographic features at rest and during exercise in young adults born preterm below 30 weeks of gestation
Pediatric Research, Published online: 02 March 2020; doi:10.1038/s41390-020-0815-8Brain inflammation and injury at 48 h is not altered by human amnion epithelial cells in ventilated preterm lambs
Pediatric Research, Published online: 02 March 2020; doi:10.1038/s41390-020-0826-5“I’m not alone”—my take-away message from the My Friend Diabetes Camp
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Abstract Recently, exploring brain activity based on functional networks during naturalistic stimuli especially music and video represents an attractive challenge because of the low signal-to-noise ratio in collected brain data. Although most efforts focusing on exploring the listening brain have been made through functional magnetic resonance imaging (fMRI), sensor-level electro- or magnetoencephalography (EEG/MEG) technique, little is known about how neural rhythms are involved...
Abstract The ability to mentally simulate an action by recalling the body sensations relative to the real execution is referred to as kinesthetic motor imagery (MI). Frontal and parietal motor-related brain regions are generally engaged during MI. The present study aimed to investigate the time course and neural correlates of complex action imagery and possible effects of expertise on the underlying action representation processes. Professional ballet dancers and controls were...
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Abstract Persisters of infectious agents are capable of surviving antibiotic treatment so the emergence of these subpopulations need to be overcome. In this study, we aimed to isolate, characterize and inhibit persister subpopulation in two clinical isolates Klebsiella pneumoniae and Proteus mirabilis. Different behavior profiles between the two isolates could be observed. The results of dose-dependent killing curve revealed that 2.3% (Klebsiella pneumoniae) versus 1.3% (Proteus...
Abstract A Gram-staining-negative, oblong or rod-shaped, non-flagellated and facultatively anaerobic bacterium, designated WN023T, was isolated from natural saline-alkali wetland soil of Binhai new district, Tianjin, China. The colonies of strain WN023T on marine agar 2216 (MA) have a brown, circular, wet pigmentation, and its cells are approximately 1–1.5 μm × 2.0–2.5 μm in size. Growth occurred at 15–45 °C, but optimally at 33–37 °C, in the presence of 5.0–25.0% (w/v) NaCl, but...
Abstract A Gram-stain-negative, non-motile and short-rod-shaped bacterium, designated as strain SY7T, was isolated from rhizosphere soil of the mangrove Kandelia obovata of Fugong village, in Zhangzhou, China. The isolate grew at 10–45 °C (optimum 30 °C), pH 6.0–10.0 (optimum pH 7.0) and 0–8% NaCl (optimum 3%, w/v). The 16S rRNA gene sequence and phylogenetic analysis revealed that strain SY7T located within the radiation of genus Nitratireductor and showed the highest sequence...
Abstract Antimicrobial resistance (AMR) is a current major health issue, both for the high rates of resistance observed in bacteria that cause common infections and for the complexity of the consequences of AMR. Pathogens like Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Mycobacterium tuberculosis among others are clear examples of antibiotic-resistant threats. Biosurfactants have recently emerged as a potential new generation of anti-adhesive and anti-biofilm...
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Abstract In systems and synthetic biology, much research has focused on the behavior and design of single pathways, while, more recently, experimental efforts have focused on how cross-talk (coupling two or more pathways) or inhibiting molecular function (isolating one part of the pathway) affects systems-level behavior. However, the theory for tackling these larger systems in general has lagged behind. Here, we analyze how joining networks (e.g., cross-talk) or decomposing networks...
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Abstract Background The evidence base for the widely accepted standard regimen of succinylcholine for rapid sequence induction (1.0 mg kg− 1) remains unclear. Methods We performed a systematic review and meta-analysis of randomized trials comparing any succinylcholine regimen with the standard regimen (1.0 mg kg− 1) and reporting on intubating...
Abstract Background Abdominal surgery is common and is associated with severe postoperative pain. The transverse abdominal plane (TAP) block is considered an effective means for pain control in such cases. The quadratus lumborum (QL) block is another option for the management of postoperative pain. The aim of this study was to conduct a meta-analysis and thereby evaluate the efficacy and safety of QL blocks and TAP blocks for pain...
Abstract Background This review and meta-analysis aims to evaluate the analgesic efficacy of continuous transversus abdominis plane (TAP) block compared with epidural analgesia (EA) in adults after abdominal surgery. Methods The databases PubMed, Embase and Cochrane Central Register were searched from inception to June 2019 for all available...
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Abstract Static in vitro cell culture studies cannot capture the dynamic concentration profiles of drugs, nutrients, and other factors that cells experience in physiological systems. This limits the confidence in the translational relevance of in vitro experiments and increases the reliance on empirical testing of exposure-response relationships and dose optimization in animal models during preclinical drug development, introducing additional challenges owing to species-specific...
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Publication date: Available online 1 March 2020Source: NeuroImageAuthor(s): Xin Di, Bharat B. Biswal
Publication date: Available online 29 February 2020Source: NeuroImageAuthor(s): Brittany L. Mitchell, Gabriel Cuéllar-Partida, Katrina L. Grasby, Adrian I. Campos, Lachlan T. Strike, Liang-Dar Hwang, Aysu Okbay, Paul M. Thompson, Sarah E. Medland, Nicholas G. Martin, Margaret J. Wright, Miguel E. Rentería
Publication date: Available online 29 February 2020Source: NeuroImageAuthor(s): Lucía Vaquero, Paul-Noel Rousseau, Diana Vozian, Denise Klein, Virginia Penhune
Publication date: Available online 29 February 2020Source: NeuroImageAuthor(s): Kathrin Kostorz, Virginia L. Flanagin, Stefan Glasauer
Publication date: Available online 29 February 2020Source: NeuroImageAuthor(s): Aki Nikolaidis, Anibal Solon Heinsfeld, Ting Xu, Pierre Bellec, Joshua Vogelstein, Michael Milham
Publication date: Available online 29 February 2020Source: NeuroImageAuthor(s): Richard F. Betzel, Lisa Byrge, Farnaz Zamani Esfahlani, Daniel P. Kennedy
Publication date: Available online 29 February 2020Source: NeuroImageAuthor(s): Josefina Maranzano, Mahsa Dadar, Maryna Zhernovaia, Douglas L. Arnold, D. Louis Collins, Sridar Narayanan
Publication date: Available online 28 February 2020Source: NeuroImageAuthor(s): Talia L. Retter, Fang Jiang, Michael A. Webster, Bruno Rossion
Publication date: Available online 28 February 2020Source: NeuroImageAuthor(s): Christoph Pfeiffer, Silvia Ruffieux, Lau M. Andersen, Alexei Kalabukhov, Dag Winkler, Robert Oostenveld, Daniel Lundqvist, Justin F. Schneiderman
Publication date: Available online 28 February 2020Source: NeuroImageAuthor(s): Irene Voldsbekk, Ivan I. Maximov, Nathalia Zak, Daniel Roelfs, Oliver Geier, Paulina Due-Tønnessen, Torbjørn Elvsåshagen, Marie Strømstad, Atle Bjørnerud, Inge Groote
Publication date: Available online 28 February 2020Source: NeuroImageAuthor(s): Miguel Guevara, Pamela Guevara, Claudio Román, Jean-François Mangin
Publication date: Available online 28 February 2020Source: NeuroImageAuthor(s): David Rosen, Yongtaek Oh, Brian Erickson, Fengqing (Zoe) Zhang, Youngmoo E. Kim, John Kounios
Publication date: Available online 28 February 2020Source: NeuroImageAuthor(s): Si Si, Yukang Su, Shun Zhang, Jinghuan Zhang
Publication date: Available online 27 February 2020Source: NeuroImageAuthor(s): Dustin Scheinost, Tiffany W. Hsu, Emily W. Avery, Michelle Hampson, R. Todd Constable, Marvin M. Chun, Monica D. Rosenberg
Publication date: Available online 27 February 2020Source: NeuroImageAuthor(s): Bidhan Lamichhane, Andrew Westbrook, Michael W. Cole, Todd Braver
Publication date: Available online 27 February 2020Source: NeuroImageAuthor(s): M. Catalina Camacho, Laura E. Quiñones-Camacho, Susan B. Perlman
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Abstract Background Although combination chemotherapy (CC) is generally recommended in recurrent or primary metastatic gastric cancer (RPMGC), the results of randomized trials are conflicting. Methods A retrospective review was conducted on 687 RPMGC patients who received palliative chemotherapy. We compared the overall survival (OS)...
Abstract Background High rates of venous thromboembolic events (VTEs), mainly in advanced disease, are reported for patients with cancer of the upper gastrointestinal tract (stomach, pancreas) and for treatment with cisplatin. Methods Exploratory analysis of VTEs reported as adverse events and serious adverse events in a prospective, randomised,...
Abstract Background Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related death in the world. N6-methyladenosine (m6A) RNA methylation is dynamically regulated by m6A RNA methylation modulators (“writer,” “eraser,” and “reader” proteins), which are associated with cancer occurrence and development. The purpose of this study was to explore the relationships between m6A RNA methylation modulators and HCC....
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