Following publication of the original article [1], an error was reported in the tagging of Joël Fokom Domgue in the author group. The tagging in this correction article has been fixed.
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Abstract Slippery slope arguments (SSAs) are used in a wide range of philosophical debates, but are often dismissed as empirically ill‐founded and logically fallacious. In particular, leading authors put forward a meta‐SSA which points to instances of empirically ill‐founded and logically fallacious SSAs and to the alleged existence of a slippery slope leading to such SSAs to demonstrate that people should avoid using SSAs altogether. In this paper, I examine these prominent calls against using...
Abstract Controlled human infection model (CHIM) studies involve the intentional exposure of healthy research volunteers to infectious agents. These studies contribute to knowledge about the cause or development of disease and to the advancement of vaccine research. But they also raise ethical questions about the kinds of risks that should be permissible and whether limits should be imposed on research risks in CHIM studies. Two possible risk thresholds have been considered for CHIM studies. The...
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Abstract Background The licensed doctor misdistribution is one of the major challenges faced by China. However, this subject remains underexplored as spatial distribution characteristics (such as spatial clustering patterns) have not been fully mapped out by existing studies. To fill the void, this study aims to explore the spatio-temporal dynamics and spatial clustering patterns of different subtypes of licensed doctors (i.e.,...
Abstract Background Residents have to learn to provide high value, cost-conscious care (HVCCC) to counter the trend of excessive healthcare costs. Their learning is impacted by individuals from different stakeholder groups within the workplace environment. These individuals’ attitudes toward HVCCC may influence how and what residents learn. This study was carried out to develop an instrument to reliably measure HVCCC attitudes...
Abstract Background People living with dementia in care homes frequently exhibit “behaviour that challenges”. Anti-psychotics are used to treat such behaviour, but are associated with significant morbidity. This study researched the feasibility of conducting a trial of a full clinical medication review for care home residents with behaviour that challenges, combined with staff training. This paper focusses on the feasibility of...
Abstract Background In increasingly constrained healthcare budgets worldwide, efforts to improve quality and reduce costs are vital. Quality Improvement Collaboratives (QICs) are often used in healthcare settings to implement proven clinical interventions within local and national programs. The cost of this method of implementation, however, is cited as a barrier to use. This systematic review aims to identify and describe studies...
Abstract Background The association between patient satisfaction and survey response is only partly understood. In this study, we describe the association between average satisfaction and survey response rate across hospital surveys, and model the association between satisfaction and propensity to respond for individual patients. Methods ...
Abstract Background Antibiotics are often prescribed inappropriately to patients with upper respiratory infection (URI) in ambulatory care settings; however, the economic burden of such prescription has not been quantitatively assessed. Here, we aimed to evaluate the additional cost of antimicrobial prescription for URI at the population level in Japan. Methods...
Abstract Background Electrolyte imbalances (EI) are common among patients. Many patients have repeated hospitalizations with the same EI without being investigated and treated. We established an electrolyte outpatient clinic (EOC) to diagnose and treat patients with EI to improve symptoms and increase their quality of life (QoL). In addition, we also wanted to reduce the number of admissions with the same EI. ...
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Nature Neuroscience, Published online: 02 March 2020; doi:10.1038/s41593-020-0598-6Chen, Deister et al. show that Shank3B-knockout mice display hypersensitivity to tactile sensory stimulation and that dysfunction of interneurons in somatosensory cortex contributes to the sensory hyper-reactivity in this mouse model of autism.
Nature Neuroscience, Published online: 28 February 2020; doi:10.1038/s41593-020-0599-5The multiplex model of the genetics of Alzheimer’s disease
Nature Neuroscience, Published online: 28 February 2020; doi:10.1038/s41593-020-0601-2Motor learning is composed of explicit ‘strategic’ components and implicit ‘automatic’ components. Miyamoto and colleagues reveal how these components work together during visuomotor adaptation, providing evidence that an implicit component corrects for a noisy explicit process.
Nature Neuroscience, Published online: 28 February 2020; doi:10.1038/s41593-020-0597-7Zhou et al. unveil a novel role for activated microglia and macrophages during wound healing after CNS injury. Microglia promote corralling and form a protective barrier at the injury penumbra via the axon guidance receptor Plexin-B2.
Nature Neuroscience, Published online: 28 February 2020; doi:10.1038/s41593-020-0600-3Implicit learning increases the fidelity of performance during motor learning by acting to adaptively clean up the noise resulting from a low-fidelity explicit strategy.
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A coroner is to write to the UK General Medical Council asking it to reform its procedures after a consultant anaesthetist killed himself within hours of receiving an email telling him he was being...
AbstractGuidelines on the treatment of tuberculosis (TB) have essentially remained the same for the past 35 years, but are now starting to change. Ongoing clinical trials will hopefully transform the...
US public health watchdogs have been failing for years in their legal duty to inform the public about the results of clinical trials, a federal court has found.The US district court for southern New...
A senior employee of the US Department of Health and Human Services has filed a whistleblower complaint alleging that untrained staff were sent without proper protective equipment to meet the first...
Recently retired doctors may be asked to return to work as part of the UK’s covid-19 response, according to health secretary Matt Hancock.Speaking on The Andrew Marr Show on 1 March, Hancock said...
Canada’s government has tabled new legislation that would remove some of the restrictions placed on medical aid in dying, most notably the requirement that applicants suffer from a terminal condition...
Two days of talks in Glasgow have shown that UK politicians are as far apart as ever in developing a shared approach to tackling record numbers of drug related deaths.Activists campaigning for better...
The covid-19 epidemic is not only viral—it is also digital.1Information spread through social and traditional media, as well as through governmental or health agencies, has reached a huge scale,...
What you need to knowLong term use of aspirin may prevent colorectal cancer in people with Lynch syndrome, a group with a high risk of colorectal cancerTreatment options for early rectal cancer...
A woman who sued three NHS trusts for negligence for not telling her while she was pregnant that her father had Huntington’s disease has lost her case in the High Court.1The woman, referred to as...
Key messagesSpending on clinical negligence is escalating, constituting a major threat to the sustainability of the NHSIn England, payments for negligence awards are resourced from the same funds...
bmj;368/feb28_10/m794/FAF1faJohn Wyn Owen approached his death in the same way as his life as director of the NHS in Wales; director general of the New South Wales Health Department in Australia; and...
bmj;368/feb28_8/m658/FAF1faNicholas Godlee came from a medical lineage: his great uncle, Sir Rickman Godlee, the first neurosurgeon to successfully remove a brain tumour, was himself the nephew of...
bmj;368/feb28_9/m796/FAF1faIain Smith Macdonald was born in Greenock. After graduating, he did national service in North Africa, then qualified in public health medicine and did a spell as a lecturer...
The fallout from former health secretary Andrew Lansley’s 2012 reorganisation of the NHS in England is still being felt. The enduring effects have largely been seen in a series of unintended...
Covid-19: school closures and bans on mass gatherings will need to be considered, says England’s CMO
School closures and bans on mass gatherings will need to be considered if there is evidence of onward transmission of covid-19 in the UK, England’s chief medical officer has said.Speaking at the...
We welcome The BMJ’s thoughtful editorial linking health to the debate on divestment.1 The increasing pressure for divestment from fossil fuels builds on a long tradition of ethical...
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