Corrugated-board explosion-proof wall is the main means to prevent explosion shock wave damage, and it is important to study the effect of different corrugated plates on the shock wave. Using a high-speed schlieren experimental system and an air overpressure test system, the wave-blocking characteristics of different forms of corrugated plates are comprehensively studied. The schlieren images were used to analyze the influence that the corrugation shape of a corrugated plate has on the shock wave...
Smoking is a major risk factor for pulmonary diseases that include chronic obstructive pulmonary diseases (COPD) and cancer. Nicotine is the toxic and addictive component of tobacco products, like cigarettes, that negatively affects the immune system. Here, we examined the effect of nicotine on the IL-22 pathway that protects lung function by increasing transepithelial resistance and epithelial cell regeneration and repair. Our results indicate that exposure to nicotine impairs the regenerative capacity...
Dates’ color is known to play a crucial role in determining the value and quality of the fruit. The color changes from the natural accepted golden color to unfavorable dark brown color during storage. In this study, the effect of different color preservation methods (modified atmosphere packaging, cold storage (4°C), sulfur dioxide gas (SO2), and blanching) and its relation to darkening due to action of the browning enzymes and melanin production were investigated. Polyphenol oxidase was shown to...
Macrophages are involved in angiogenesis, an essential process for organ growth and tissue repair, and could contribute to the pathogenesis of angiogenesis-related diseases such as malignant tumors and diabetic retinopathy. Recently, long noncoding RNAs (lncRNAs) have been proved to be important in cell differentiation, organismal development, and various diseases of pathological angiogenesis. Moreover, it has been indicated that numerous lncRNAs exhibit different functions in macrophage infiltration...
The nuclear transcription factor p53, discovered in 1979, has a broad range of biological functions, primarily the regulation of apoptosis, the cell cycle, and DNA repair. In addition to these canonical functions, a growing body of evidence suggests that p53 plays an important role in regulating intracellular redox homeostasis through transcriptional and nontranscriptional mechanisms. Oxidative stress induction and p53 activation are common responses to chemical exposure and are suggested to play...
Objective. To investigate the protective effects and mechanisms of human tissue kallikrein 1 (hKLK1) on type 1 diabetes mellitus- (DM-) induced erectile dysfunction in rats. Materials and Methods. The homozygous transgenic rats (TGR) harboring the hKLK1 gene and age-matched wild-type Sprague Dawley rats (WTR) were involved, and intraperitoneal injection of streptozotocin was utilized to induce diabetes in rats. Forty-eight-week-old male rats were randomly divided into a WTR group, TGR group, diabetic...
Pelargonium sidoides (PS) is traditionally used to treat respiratory and gastrointestinal infections, dysmenorrhea, and hepatic disorders in South Africa. Coptis Rhizoma (CR) is used to treat gastroenteric disorders, cardiovascular diseases, and cancer in East Asia. In the present study, we intended to observe the possible beneficial antiasthma effects of PS and CR on the ovalbumin- (OVA-) induced asthma C57BL/6J mice. Asthma in mice was induced by OVA sensitization and subsequent boosting. PS + CR...
Background. The ethanol extract of Artocarpus champeden stem bark (ACEE) has been proven to exhibit antimalarial activity. Despite the antimalarial effects observed, mechanisms of immune response to explain the antimalarial activity of ACEE remain poorly characterized. Here, we show the production of pro- and anti-inflammatory cytokines T helper 1 (Th1: IFN-γ, TNF-α) and T helper 2 (Th2: IL-10) from Plasmodium berghei-infected mice treated with formulated ACEE in order to better characterize the...
In this study, we investigated the relaxation effect and mechanisms of patchouli alcohol (PA) on rat corpus cavernosum. Corpus cavernosum strips were used in organ baths for isometric tension studies. The results showed that PA demonstrated concentration-dependent relaxation effect on rat corpus cavernosum. The relaxant response to PA was not influenced by tetrodotoxin and atropine while it was significantly inhibited by removal of endothelium. L-NG-nitroarginine methyl ester (L-NAME, a nitric oxide...
This paper investigates the permeability characteristics of compacted loess by focusing on the anisotropy parallel and perpendicular to the compaction. Three tests are conducted on compacted loess: triaxial permeability test under confining pressure consolidation, triaxial permeability test under K0 consolidation, and SEM test. Samples are maintained and tested at different dry densities under saturated conditions. The test results show that the saturated permeability coefficient of compacted loess...
Patients with systemic lupus erythematosus (SLE) are at increased risk for infection including opportunistic infections. Fungal infection in particular can be difficult to diagnose and treat and often can be life-threatening in the immunocompromised patient. We present a case in which a patient with SLE presented to the hospital with shortness of breath and cough. Throughout the hospital course, the patient’s condition continued to decline leading to acute respiratory failure, and eventually, the...
In order to further study the performance of aerostatic bearing, an aerostatic bearing with a multihole integrated restrictor was proposed in this paper. Based on the physical model of aerostatic bearings, the governing equation was established, deduced discretely, and solved numerically by the finite-difference method and flow balance principle in Cartesian coordinates. The bearing capacity and stiffness of aerostatic bearings have been analyzed, and the relevant experimental research has been carried...
In order to effectively improve vehicle riding comfort, handling stability, and realize vibration energy recovery, a new kind of electromagnetic linear hybrid active suspension (EMLHAS) integrated with linear motor and solenoid valve shock absorber is put forward. Firstly, for the analysis of the suspension performance, a quarter dynamic model of EMLHAS is established. At the same time, the mathematical models of a linear motor, including the active state and energy-regenerative state, are found....
Bacillus megaterium NCT-2 is a nitrate-uptake bacterial, which shows high bioremediation capacity in secondary salinization soil, including nitrate-reducing capacity, phosphate solubilization, and salinity adaptation. To gain insights into the bioremediation capacity at the genetic level, the complete genome sequence was obtained by using a multiplatform strategy involving HiSeq and PacBio sequencing. The NCT-2 genome consists of a circular chromosome of 5.19 Mbp and ten indigenous plasmids, totaling...
Posterior Reversible Encephalopathy Syndrome in a Patient with Hemorrhagic Fever with Renal Syndrome
We presently report the case of hantavirus infection in a 45-year-old male who was hospitalized to our clinic of infectious diseases, with fever, myalgia, vomiting, nausea, headache, and abdominal pain. The physical findings included hepatomegaly, splenomegaly, rash, and conjunctival injection. Eight days before the start of complaints, the patient has cut trees in the mountain. An acute renal failure was observed with an oliguria and an increase of serum creatinine and blood urea nitrogen. Urinalysis...
Due to the increasing demand on developing good insulation, several researchers have performed experimental studies to prove the effectiveness and capabilities of transformer oil. This is done by suspending nanosized solid particles in the oil (nanofluid) for transformer applications. In brief, this paper presents a compilation of research studies which is divided into three parts. Part I discuss the preparation of the nanofluid which involves different types of nanomaterials, the optimal amount...
In recent years, microwave heating techniques for quantum dot (QD) synthesis have come to supplement the typical hot-injection methods. In addition to increasing control and replicability, microwave synthesis can be up-scaled to industry standards, an advantage that increases its lucrativeness. This study depicts a strategy to take a hot-injection procedure for cadmium selenide (CdSe) QD synthesis that is safe enough for undergraduate research labs and adapt it to an easier, more energy-efficient...
The complexity of providing timely and cost-effective distribution of finished goods from industrial facilities to customers makes effective operational coordination difficult, yet effectiveness is crucial for maintaining customer service levels and sustaining a business. Logistics planning becomes increasingly complex with growing numbers of customers, varied geographical locations, the uncertainty of future orders, and sometimes extreme competitive pressure to reduce inventory costs. Linear optimization...
Objective. The aim of this study was to investigate the expression of Snail, galectin-3, and IGF1R in benign and malignant pheochromocytoma and paraganglioma (PPGL) and explore their role in the diagnosis of malignant PPGL. Methods. We retrospectively collected and analyzed surgical tumor tissue from 226 patients initially diagnosed with PPGL who underwent surgery from Jan. 2009 to Jan. 2016 at West China Hospital, Sichuan University. We observed and quantified the expression of Snail, galectin-3,...
Objective. To determine the molecular characterization and disease-associated complications of beta-thalassemia intermedia (β-TI) patients in Sulaymaniyah province, northeastern Iraq. Methods. A total of 159 β-TI patients from 114 families were enrolled. Detection of β-thalassemia mutations was done by reverse hybridization technique and direct gene sequencing. Also, the clinical and hematological data were collected through an electronic-based medical recording system using a designed comprehensive...
Polycystic ovary syndrome (PCOS) is a common female endocrine system disease that affects 17.8% of women of reproductive age and leads to infertility, obesity, glucose metabolic disorders, cardiovascular disease, and body-mind problems. However, the etiology of PCOS remains unclear. Follicular growth is disrupted as a result of ovarian hyperandrogenism and distorted intraovarian paracrine signaling in women with PCOS. Microcommunication between oocytes and cumulus cells plays a critical role in folliculogenesis....
Purpose. Pyroptosis has been known to play a vital role in the inflammation process which was induced by infection, injury, or inflammatory disease. The present study was aimed at evaluating the percentage of peripheral blood mononuclear cell (PBMC) pyroptosis in septic patients and assessing the correlation of PBMC pyroptosis with the severity and the mortality of septic patients. Methods. 128 trauma-induced patients with sepsis were enrolled in this prospective cohort study. Blood samples were...
Periodic solutions of the Coulomb equation motion for three equal negative point charges in the field of six equal positive point charges fixed in vertices of a convex octagon are found. The system possesses an equilibrium configuration. The Lyapunov center theorem is applied.
The study aims to explore the access of mobile phone, emerging technologies, and use of the mobile phone by the youth of Gilgit-Baltistan (GB), Pakistan, for learning and safety and security purposes. Structured questionnaires were used to collect the data. The descriptive statistics was employed to test the research model. Among the 300 distributed sample size, 272 participants responded back including 133 male and 139 female students of Karakoram International University (KIU) from eight districts...
Vehicular Ad hoc NETworks (VANETs) are becoming an important part of people’s daily life, as they support a wild range of applications and have great potential in critical fields such as accident warning, traffic control and management, infotainment, and value-added services. However, the harsh and stringent transmission environment in VANETs poses a great challenge to the efficient and effective data dissemination for VANETs, which is the essential in supporting and providing the desired applications....
The antioxidant activity of garcinol has been identified as the basis for various bioactivities in it, and the genus Garcinia is the main source for the garcinol. G. quaesita, which is endemic to Sri Lanka, is a representative member of genus Garcinia, and the dried fruit rind of G. quaesita is used practically in all curry preparations to impart a sour flavor. In our study, garcinol was isolated (yield: 3.67%) from the dried fruit rind of G. quaesita, for the first time. Further, how cooking conditions...
Speeding is a major risk factor for traffic-related injuries. As a countermeasure against speeding, automated speed enforcement systems (ASES) have been deployed in many countries. However, drivers’ awareness of enforcement locations allows themselves to adjust vehicle speeds in the vicinity of the enforcement locations. This enforcement avoidance behavior leads to a criticism of the effectiveness of ASES, in which the system promotes abrupt changes in vehicle speed near enforcement locations, increasing...
A synthetic aperture radar (SAR) target recognition method is proposed via linear representation over the global and local dictionaries. The collaborative representation is performed on the local dictionary, which comprises of training samples from a single class. Then, the reconstruction errors as for representing the test sample reflect the absolute representation capabilities of different training classes. Accordingly, the target label can be directly decided when one class achieves a notably...
Global Navigation Satellite System Real-Time Kinematic (GNSS-RTK) technology is widely used in vehicle navigation, but in complex environments such as urban high-rise street, wooded street, overpass, and tunnel, satellite signals are prone to attenuation or even unavailability. It brings great challenges to the continuous high-precision navigation. For this reason, a tightly coupled (TC) integration algorithm for GPS (Global Positioning System)/BDS (BeiDou Navigation Satellite System)/MEMS-INS (Micro-Electro-Mechanical...
In order to improve the position accuracy and trajectory accuracy of a 6R robotic arm, a robot arm inverse solution algorithm based on the MQACA- (improved quantum ant colony-) RBF network is proposed. This algorithm establishes the prediction model through the neural network and uses the quantum ant colony algorithm to optimize the output weight. In order to solve the problem that the quantum ant colony algorithm has low convergence precision and easy to fall into the local optimal solution in the...
The paper discusses the solution of the assignment task between two groups of mobile (MR) objects. The assignment task is to determine the purpose of MR to each other when playing football. This article analyzes well-known works devoted to the tasks of assignments, and the relevance of research in this area is noted. The task of target distribution is successfully solved with a small degree of uncertainty. The urgency of further research to solve the problem of target distribution in conditions of...
In the research and development of intelligent prosthesis, some of performance test experiments are required. In order to provide an ideal experimental platform for the performance test of intelligent prosthesis, a heterogeneous biped walking robot model is proposed. Artificial leg is an important part of heterogeneous biped walking robot, and its main function is to simulate the disabled a healthy normal gait, which provides intelligent bionic legs gait to follow the target trajectory. The pneumatic...
A monolithic imprinted atenolol column was constructed by in situ polymerisation using a methacrylic acid monomer and a 1 : 1 (v/v) porogen of propanol: toluene with two template: monomer: crosslinker combinations, namely, MIP 1 (1 : 4 : 20) and MIP 2 (1 : 5 : 20). Physical characterisation of the monolithic columns consisted of permeability testing, Fourier transform infrared (FTIR) testing, surface area analysis (SAA), and scanning electron microscopy (SEM). The permeability value of four monolithic...
This paper reports the molar heat capacities of β-CsB5O8·4H2O, which were measured by an accurate adiabatic calorimeter from 298 to 373 K with a heating rate of 0.1 K/min under nitrogen atmosphere. Neither phase transition nor thermal anomalies were observed. The molar heat capacity against temperature was fitted to a polynomial equation of Cp,m (J·mol−1·K−1) = 618.07702 + 39.52669[T − (Tmax + Tmin)/2]/(Tmax − Tmin)/2] − 3.46888[(T − (Tmax + Tmin)/2)/(Tmax − Tmin)/2]2 + 7.9441[(T − (Tmax+ Tmin)/2)/(Tmax − Tmin)/2]3....
In this paper, we give a geometric interpretation of the Laplacian matrix of a connected nonsingular mixed graph which generalizes the results of M. Fiedler (M. Fiedler, Geometry of the Laplacian, Linear Algebra Appl., 2005, 403: 409–413). In addition, the relations of geometric properties between a connected (singular or nonsingular) mixed graph, and all its resigned graphs will be characterized.
Dendrimers are highly branched organic macromolecules with successive layers of branch units surrounding a central core. Some properties like toxicity, entropy, and heats of vaporization of these dendrimers can be forecasted using topological indices. The present article is devoted to study of irregularity indices of three well-known classes of dendrimers, namely, nanostar dendrimer D[p], fullerene dendrimer NS4[p], and polymer dendrimerNS5[p], where is the step size. We also see the relation of...
Karst water in northern China is an important water source for economic and social development in its distribution area and water source for ecological function guarantee. With the enhancement of human activities, the water quality of karst water in the north has deteriorated and the bearing capacity of economic activities and social and ecological environment has weakened. The study on the distribution characteristics and source analysis of toxic substances in typical karst springs in northern China...
In this study, concentrations, sources, and ecological risk of 16 polycyclic aromatic hydrocarbons (PAHs) in 41 surface water samples collected from Wuhai and Lingwu sections of the Yellow River were investigated. The results showed that total PAH concentrations varied from 27.5 ng/L to 234 ng/L and from 135 ng/L to 265 ng/L in surface water of Wuhai and Lingwu sections, respectively. Source identification was performed by using principal component and multiple linear regression analysis. PAHs in...
This study was to explore the therapeutic effect and mechanism of puerarin (PUE) combined with PEGylated nanoparticles on a rat cerebral infarction cell model. In this context, PEG-PLGA/PUE nanoparticles were prepared by the thin-film hydration method, and the toxicity of PEG-PLGA/PUE nanoparticles to brain capillary endothelial cell (BCEC) was detected by MTT. The BCEC/TF cell model was obtained by induction of BCEC cells with TNF-α. The BCEC/TF cell model was identified by immunofluorescence; the...
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