Karst water in northern China is an important water source for economic and social development in its distribution area and water source for ecological function guarantee. With the enhancement of human activities, the water quality of karst water in the north has deteriorated and the bearing capacity of economic activities and social and ecological environment has weakened. The study on the distribution characteristics and source analysis of toxic substances in typical karst springs in northern China...
Fri Feb 28, 2020 18:35
In this study, concentrations, sources, and ecological risk of 16 polycyclic aromatic hydrocarbons (PAHs) in 41 surface water samples collected from Wuhai and Lingwu sections of the Yellow River were investigated. The results showed that total PAH concentrations varied from 27.5 ng/L to 234 ng/L and from 135 ng/L to 265 ng/L in surface water of Wuhai and Lingwu sections, respectively. Source identification was performed by using principal component and multiple linear regression analysis. PAHs in...
Fri Feb 28, 2020 18:35
This study was to explore the therapeutic effect and mechanism of puerarin (PUE) combined with PEGylated nanoparticles on a rat cerebral infarction cell model. In this context, PEG-PLGA/PUE nanoparticles were prepared by the thin-film hydration method, and the toxicity of PEG-PLGA/PUE nanoparticles to brain capillary endothelial cell (BCEC) was detected by MTT. The BCEC/TF cell model was obtained by induction of BCEC cells with TNF-α. The BCEC/TF cell model was identified by immunofluorescence; the...
Fri Feb 28, 2020 18:35
Diethylhexyl phthalate (DEHP) is a common plasticizer in industrial production. Recently, environmental problems caused by microplastics have drawn wide attention. As the microplastics have a large specific surface area, the release rate of the plasticizer from the microplastics to the environment is accelerated. The DEHP in the wastewater enters the wastewater treatment plants (WWTPs) along with the urban pipeline. After DEHP enters the WWTPs, it may affect the anaerobic fermentation with waste...
Fri Feb 28, 2020 18:35
Background. There is evidence that gross motor function impacts the health-related quality of life of young adults with cerebral palsy. This study aimed to assess gross motor function, oral health and oral health-related quality of life (OHRQoL), and the relationship between them in young adults with cerebral palsy. Methods. The sample comprised 46 individuals aged between 13 and 17 years with Gross Motor Function Classification Scores (GMFCS) ranging from level I to level III. The individuals and...
Fri Feb 28, 2020 17:35
Primary breast neoplasms are rare in adolescent females, most of which are benign. Phyllodes tumors constitute a remarkably small subset of breast neoplasms (0.3-0.9%) with malignant phyllodes tumors being even more uncommon. Malignant phyllodes tumors tend to progress rapidly though only 1.5% metastasize. They are also associated with a higher rate of recurrence than their benign counterparts, underlying the importance of adequate surgical margins. It is therefore imperative to be able to identify...
Fri Feb 28, 2020 17:20
Cementitious composites usually work under moisture condition. Presently, the piezoresistivity of cementitious composites incorporating multiwalled carbon nanotubes (MWCNTs) due to moisture variation was experimentally investigated. The variation of moisture content was controlled by drying specimens in an oven. In most cases of moisture content, the composites were observed to present positive piezoresistivity during the process of cyclic compression. While moisture content was in a specific range,...
Fri Feb 28, 2020 17:05
An algorithm using the differential transformation which is convenient for finding numerical solutions to initial value problems for functional differential equations is proposed in this paper. We focus on retarded equations with delays which in general are functions of the independent variable. The delayed differential equation is turned into an ordinary differential equation using the method of steps. The ordinary differential equation is transformed into a recurrence relation in one variable using...
Fri Feb 28, 2020 17:05
Introduction. Restoring lateral ankle stability following distal resection of the fibula is a difficult procedure for which several surgical techniques have been proposed. Each of these techniques has potential drawbacks. This report presents a new option for fibular reconstruction. Case Study. We report the case of a 68-year-old male with evolving pain in the left ankle throughout the past 3 months. Three years prior to consultation, he underwent left nephrectomy for clear-cell adenocarcinoma. A...
Fri Feb 28, 2020 16:50
Oxidative stress (OS) is a crucial factor influencing the development of Parkinson’s disease (PD). Here we first reported that Lindleyin (Lin), one of the major components of rhubarb, possessed neuroprotective effects against H2O2-induced SH-SY5Y cell injury and MPTP-induced PD of C57BL/6 mice. The results showed that Lin can decrease cell death and apoptotic rate induced by H2O2 through inhibiting mitochondrial apoptotic pathway and increasing the activities of SOD, GSH-Px, and CAT as well as decreasing...
Fri Feb 28, 2020 16:35
In this article, an attempt has been made to estimate the Modelling Error (ME) associated with compression capacity models available in international standards for different failure modes of compression members fabricated from Cold-Formed Steel (CFS) lipped channel sections. For the first time, a database has been created using test results available in the literature for compression capacities of CFS lipped-channel sections. The database contains details of 273 numbers of compression member tests...
Fri Feb 28, 2020 16:35
It has been shown that the inflammatory cytokine tumor necrosis factor α (TNFα) plays a role in the development of hypertension and end-stage renal diseases. We hypothesize that TNFα contributes to endothelial dysfunction and cardiac and vascular injury in deoxycorticosterone acetate (DOCA)/salt-hypertensive mice. The wild-type or TNFα-deficient mice were uninephrectomized and implanted with DOCA pellet treatment for 5 weeks; the mice were given either tap water or 1% NaCl drinking water. DOCA mice...
Fri Feb 28, 2020 16:35
Background. Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia. It affects millions of people globally. In spite of many antidiabetic drugs that are available, an adequate level of control remains challenging. Hydroxychloroquine is an immunomodulatory drug that has been used for the treatment of malaria and autoimmune diseases. There is an emerging evidence that suggests its beneficial effect against diabetes mellitus. Therefore, this systematic review is...
Fri Feb 28, 2020 16:20
With growing worldwide interests in commercial, scientific, and military issues, there has been a corresponding rapid growth in demand for the development of unmanned aerial vehicles (UAVs) with more reliable and safer motion control abilities. This paper presents a new nonlinear path following scheme integrated with a heading control law for achieving accurate and reliable path following performance. Both backstepping and finite-time techniques are employed for developing the path following and...
Fri Feb 28, 2020 16:05
The inverse problem is always one of the important issues in the field of fluid machinery for the complex relationship among the blade shape, the hydraulic performance, and the inner flow structure. Based on Bayesian theory of posterior probability obtained from known prior probability, the inverse methods for the centrifugal pump blade based on the single-output Gaussian process regression (SOGPR) and the multioutput Gaussian process regression (MOGPR) were proposed, respectively. The training sample...
Fri Feb 28, 2020 15:51
Focusing on the tailings containing high sodium silicate (water glass), this study conducted laboratory experiments and semi-industrial tests of flocculation and sedimentation for rapid tailings dewatering. Various reagent combinations, lime and anionic flocculant (APAM) (L&A), sulfuric acid and APAM (S&A), and calcium chloride and APAM (C&A), were tested. The results show that (i) all the three combinations presented a good effect in the laboratory experiments, and the relatively optimum...
Fri Feb 28, 2020 15:50
In this paper, an innovative approach based on an artificial neural network (ANN) load forecasting model to improve the distribution system state estimation accuracy is proposed. High-quality pseudomeasurements are produced by a neural model fed with both exogenous and historical load information and applied in a realistic measurement scenario. Aggregated active and reactive powers of small or medium enterprises and residential loads are simultaneously predicted by a one-step ahead forecast. The...
Fri Feb 28, 2020 15:50
In this study, a novel mathematical model based on third-order nonlinear multisingular functional differential equations (MS-FDEs) is presented. The designed model is solved by using a well-known differential transformation (DT) scheme that is a very credible tool for solving the nonlinear third-order nonlinear MS-FDEs. In order to check the exactness, efficacy, and convergence of the scheme, some numerical examples are presented based on nonlinear third-order MS-FDEs and numerically solved by using...
Fri Feb 28, 2020 15:35
The knowledge on strength properties of porous metals in compression is essential in tailored application design, as well as in elaboration of general material models. In this article, the authors propose specification details of the ANN architecture for adequate modelling of the phenomenon of compressive behaviour of open-cell aluminum. In the presented research, an algorithm was used to build different structures of artificial neural networks (ANNs), which approximated stress-strain relations of...
Fri Feb 28, 2020 15:35
Introduction. Elderly patients are underrepresented from a majority of clinical trials and the choice of the best treatment becomes a challenge. The optimal treatment should be personalized and based on a multidisciplinary approach that includes radiation oncologists, surgeons, geriatricians, medical oncologists, social workers, and support services. The global evaluation of the patients and the creation of nomograms may facilitate the definition of long-term treatment benefits minimizing the use...
Fri Feb 28, 2020 15:35
Abstract In this study, the exact contribution of T. versicolor fungal biomass and laccase in the removal of the Orange II dye from liquid culture was determined. Biomass and laccase were produced with three different carbon sources [bran flakes (BF), wheat bran (WB) and wheat flour (WF)]. The contribution of the biomass and the laccase enzyme in the removal of the Orange II dye was assessed as follows: (A) in vivo treatment with fungal biomass; in vivo treatment with fungal...
Mon Mar 02, 2020 02:00
Abstract Osteosarcoma (OS) is a rare aggressive bone, presenting low patient survival rate, high metastasis and relapse occurrence, mostly due to multi-drug resistant cells. To surpass that, the use of nanomedicine for the targeted delivery of genetic material, drugs or both have been extensively researched. In this review, we address the current situation of the disorder and some gene therapy options in the nanomedicine field that have been investigated. Among them, polymeric...
Mon Mar 02, 2020 02:00
Abstract Statins, the drugs for the treatment of dyslipidemia, have been suggested to impact insulin sensitivity, resulting in pancreatic β-cell dysfunction, and consequently, lead to new onset of diabetes. Taking this as a clue, the present study was designed to evaluate the protective effect of sesamol (a known antioxidant, antidiabetic and antidyslipidemic agent) against the diabetogenic potential of simvastatin. The toxic effects of simvastatin and sesamol on MIN6 insulinoma...
Mon Mar 02, 2020 02:00
Abstract In the current study, the production of novel glutaminase free l-asparaginase from a new microbial source (Pseudomonas resinovorans IGS-131) is reported. Optimization of l-asparaginase production using conventional and statistical optimization techniques resulted in an enzyme yield of 37.63 IU/mL, which was 3.45-fold higher than the initial enzyme activity (i.e., 10.91 IU/mL). l-Asparaginase production from P. resinovorans IGS-131 was successfully carried out at the...
Mon Mar 02, 2020 02:00
Abstract 2-acetyl-1-pyrroline (2AP) is a principal aroma compound in scented rice and a mutation in betaine aldehyde dehydrogenase 2 (OsBADH2) is responsible aroma in scented rice. The present study was aimed at inducing 2AP production in non-scented indica rice cultivar IR-64 by silencing OsBADH2 via RNAi technique. A vector pBSK was used for the construction of RNAi cassette and pRI101ON as a binary vector. Agrobacterium (GV3101)-mediated transformation was done using embryogenic...
Mon Mar 02, 2020 02:00
Abstract Schinus terebinthifolia leaf lectin (SteLL) was reported to be an antimicrobial and antitumor agent. In this work, we evaluated the immunomodulatory activity of SteLL on mice splenocytes and also determined its native molecular mass and putative sequence similarities with plant proteins. The effects of SteLL (12.5 μg/mL) on viability, cytosolic Ca2+ concentration ([Ca2+]cyt), cytosolic and mitochondrial levels of reactive oxygen species (ROS), and mitochondrial transmembrane...
Mon Mar 02, 2020 02:00
Abstract The present research reports a detailed in silico analysis of chromatin assembly factor-1 (CAF-1) family in human malaria parasite Plasmodium falciparum. Our analysis revealed five chromatin assembly factor-1 genes in P. falciparum (PfCAF-1) and the PfCAF-1 family was divided into two classes where, Class A belongs to the CAF-1 complex and others are kept in Class B. For comparative studies, orthologs of PfCAF-1 family were identified across 53 eukaryotic species and...
Fri Feb 28, 2020 02:00
The aim of this study was to determine the effects of acupotomy on energy crises in rat trigger points (TrPs) by measuring mechanical pain thresholds (MPTs) and levels of acetylcholinesterase (AChE), free sarcoplasmic calcium (Ca2+), adenosine 5′-triphosphate (ATP), adenosine 5′-monophosphate (AMP), substance P (SP), and calcitonin gene-related peptide (CGRP) in rat muscle TrP tissue. Male Sprague Dawley rats (n = 32) were randomly divided into four groups: control, TrP, acupotomy, and lidocaine...
Fri Feb 28, 2020 15:35
Additive manufacturing (AM) for fabricating 3D metallic parts has recently received considerable attention. Among the emerging AM technologies is ultrasonic additive manufacturing (UAM) or ultrasonic consolidation (UC), which uses ultrasonic vibrations to bond similar or dissimilar materials to produce 3D builds. This technology has several competitive advantages over other AM technologies, which includes fabrication of dissimilar materials and complex shapes, higher deposition rate, and fabrication...
Fri Feb 28, 2020 15:20
Transcutaneous electrical nerve stimulation (TENS) has been reported to attenuate postural sway; however, the results are inconclusive, with some indicating the effect and others not. The study aimed to evaluate the effect of sensory sub- and suprathreshold low-frequency TENS applied through the plantar surface and posterior aspect of shanks on postural sway. In a group of healthy community-dwelling older adults, TENS was delivered with two different current intensities: (1) subsensory which is below...
Fri Feb 28, 2020 15:20
Inflammatory bowel diseases is a group of inflammatory diseases. The pathogenesis of diseases is multifactorial, which may include a Western-type diet. Diseases occur with periods of recurrence and remission. Many factors can have a beneficial effect on reducing the frequency of recurrence and prolonging the remission period. Such ingredients include dietary fibre, mono- and polyunsaturated fatty acids, certain vitamins (D, C, and E), flavonoids, and minerals such as zinc and selenium. Properly selected...
Fri Feb 28, 2020 14:50
Purpose. To evaluate the clinical and in vivo confocal microscopy outcome of lamellar keratoplasty combined with amniotic membrane transplantation for the treatment of corneal perforations. Methods. In this retrospective, noncomparative, and interventional case series, 13 eyes of 13 patients with corneal perforation were included. All eyes were treated with lamellar keratoplasty combined with amniotic membrane transplantation for corneal reconstruction. Age, underlying etiology, location, size of...
Fri Feb 28, 2020 14:50
Fri Feb 28, 2020 14:50
Background and Aim. Bitter melon (Momordica charantia/MC) contains charantin that has antidiabetic properties as an α-glucosidase inhibitor and antioxidative properties. Lactic acid fermentation using Lactobacillus fermentum LLB3 increased its antioxidative properties. The study was aimed to analyse the difference of the treatment that influences blood glucose and SOD level before and after treatment compared to acarbose. Experimental procedure. A total of 24 male Sprague-Dawley rats were used. Diabetes...
Fri Feb 28, 2020 14:35
Tabu Search and Machine-Learning Classification of Benign and Malignant Proliferative Breast Lesions
Breast cancer is the most diagnosed cancer among women around the world. The development of computer-aided diagnosis tools is essential to help pathologists to accurately interpret and discriminate between malignant and benign tumors. This paper proposes the development of an automated proliferative breast lesion diagnosis based on machine-learning algorithms. We used Tabu search to select the most significant features. The evaluation of the feature is based on the dependency degree of each attribute...
Fri Feb 28, 2020 14:35
The most common use of robots is to effectively decrease the human’s effort with desirable output. In the human-robot interaction, it is essential for both parties to predict subsequent actions based on their present actions so as to well complete the cooperative work. A lot of effort has been devoted in order to attain cooperative work between human and robot precisely. In case of decision making , it is observed from the previous studies that short-term or midterm forecasting have long time horizon...
Fri Feb 28, 2020 14:20
Background. Epoxide hydrolase 2 (EPHX2) gene coding for soluble epoxide hydrolase is a potential candidate in the pathogenesis of hypertension. Objectives. We aimed to assess the association of a missense mutation, R287Q, in EPHX2 gene with primary hypertension risk and examine its association with enzyme activity of soluble epoxide hydrolase. Methods. This study involved 782 patients with primary hypertension and 458 healthy controls. Genotyping was done using TaqMan technique. Activity of soluble...
Fri Feb 28, 2020 14:20
Validity of the approximate equation for predicting compressive stress in the posttensioned anchorage zone presented in the AASHTO LRFD Bridge Design Specifications was investigated in this study. Numerical analysis based on the finite element method (FEM) and theoretical analysis showed that the AASHTO formula gives relatively accurate stress values when the effect of duct holes is neglected. However, it was found that the formula can significantly overestimate the stresses in the actual prestressed...
Fri Feb 28, 2020 14:20
Paenibacillus polymyxa is a plant growth-promoting rhizobacterium that has immense potential to be used as an environmentally friendly replacement of chemical fertilizers and pesticides. In the present study, Paenibacillus polymyxa SK1 was isolated from bulbs of Lilium lancifolium. The isolated endophytic strain showed antifungal activities against important plant pathogens like Botryosphaeria dothidea, Fusarium oxysporum, Botrytis cinerea, and Fusarium fujikuroi. The highest percentage of growth...
Fri Feb 28, 2020 14:20
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