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Δευτέρα 2 Μαρτίου 2020


Genome analysis of Lactobacillus plantarum subsp. plantarum KCCP11226 reveals a well-conserved C 30 carotenoid biosynthetic pathway
Abstract Carotenoids are group of colored terpenoids with antioxidant properties and widespread in nature including in microorganisms. Lactobacillus plantarum subsp. plantarum KCCP11226 was previously isolated from kimchi, while exhibiting the production of 4,4′-diaponeurosporene as a C30 carotenoid. In this study, full genome sequencing of the strain KCCP11226 was performed. Genome analysis revealed that the dehydrosqualene synthase (crtM) and dehydrosqualene desaturase (crtN)...
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Isolation and Characterization of Plant Growth-Promoting Endophytic Bacteria Paenibacillus polymyxa SK1 from Lilium lancifolium
Paenibacillus polymyxa is a plant growth-promoting rhizobacterium that has immense potential to be used as an environmentally friendly replacement of chemical fertilizers and pesticides. In the present study, Paenibacillus polymyxa SK1 was isolated from bulbs of Lilium lancifolium. The isolated endophytic strain showed antifungal activities against important plant pathogens like Botryosphaeria dothidea, Fusarium oxysporum, Botrytis cinerea, and Fusarium fujikuroi. The highest percentage of growth...
Hindawi Publishing Corporation
Fri Feb 28, 2020 14:20
Oncological Treatment Considerations Differ across Surgical Subspecialties Treating Malignant Peripheral Nerve Sheath Tumors: An International Survey
Background. Malignant peripheral nerve sheath tumors (MPNSTs) are rare and aggressive soft tissue sarcomas (STS) that, because of their origin, are operated by several surgical subspecialties. This may cause differences in oncologic treatment recommendations based on presentation. This study investigated these differences both within and between subspecialties. Methods. A survey was distributed among several (inter)national surgical societies. Differences within and between subspecialties were analyzed...
Hindawi Publishing Corporation
Fri Feb 28, 2020 14:05
Prevalence and Predictors of Nonadherence to Diet and Physical Activity Recommendations among Type 2 Diabetes Patients in Southwest Ethiopia: A Cross-Sectional Study
Background. Nonadherence to lifestyle modification recommendations is a major challenge in the management of diabetes mellitus. This study was conducted to measure the prevalence and predictors of nonadherence to diet and physical activity recommendations among type 2 diabetes patients (T2D). Methods. A cross-sectional study involving 322 type 2 diabetes patients was conducted from April 1 to June 30, 2019. Data were collected through face-to-face interviews using structured and pretested questionnaire....
Hindawi Publishing Corporation
Fri Feb 28, 2020 14:05
trans-Cinnamaldehyde Reverses Depressive-Like Behaviors in Chronic Unpredictable Mild Stress Rats by Inhibiting NF-κB/NLRP3 Inflammasome Pathway
trans-Cinnamaldehyde (TCA) is the main active component extracted from Cinnamomum cassia (C. cassia), which has many pharmacological effects, such as anti-inflammation, lowering blood glucose, and improving nerve function. However, there is no report of TCA in the treatment of depression. The purpose of this study was to investigate the antidepressant-like effect of TCA and the mechanism of NF kappa B (NF-κB) pathway and NLRP3 inflammasome inhibition by TCA. We divided 40 rats into the control group,...
Hindawi Publishing Corporation
Fri Feb 28, 2020 14:05
Real-Time Detection of Hemothorax and Monitoring its Progression in a Piglet Model by Electrical Impedance Tomography: A Feasibility Study
Hemothorax is a serious medical condition that can be life-threatening if left untreated. Early diagnosis and timely treatment are of great importance to produce favorable outcome. Although currently available diagnostic techniques, e.g., chest radiography, ultrasonography, and CT, can accurately detect hemothorax, delayed hemothorax cannot be identified early because these examinations are often performed on patients until noticeable symptoms manifest. Therefore, for early detection of delayed hemothorax,...
Hindawi Publishing Corporation
Fri Feb 28, 2020 14:05
Typology of Sounding Curves and Lithological 1D Models of Mineral Prospecting and Groundwater Survey within Crystalline Basement Rocks in the East of Cameroon (Central Africa) Using Electrical Resistivity Method and Koefoed Computation Method
Resistivity method using seventy-sixth (976) Schlumberger vertical electrical soundings along forty-one (41) profiles are conducted in the Batouri and Ngoura subdivisions, East region of Cameroon, to investigate the subsurface layering, mineral potential, and groundwater resource characteristics. Results of quantitative and qualitative interpretation of data using Koefoed computation method reveal two to five layers having geometrical and electrical characteristics of geological layer models: topsoil...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:50
Diagnostic and Management Pathways for Pulmonary Carcinoid Tumours in the United Kingdom: Results from the National Lung Neuroendocrine Tumour Pathway Project
There is inconsistency among published guidelines for the optimal diagnostic and management pathways for patients with typical (TC) or atypical (AC) pulmonary carcinoid tumours. We conducted a UK-wide clinician survey to assess current practice for the diagnosis, management, and follow-up of patients with TC/AC and descriptively compared management between European Neuroendocrine Tumor Society (ENETS) accredited centres of excellence (CoE) and nonaccredited centres (non-CoE). Twenty-seven clinicians...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:50
Long-Term Exchange Rate Probability Density Forecasting Using Gaussian Kernel and Quantile Random Forest
In the midst of macro-economic uncertainties, accurate long-term exchange rate forecasting is crucial for decision-making and planning. To measure the uncertainty associated with exchange rate and obtaining additional information of future exchange rate, a hybrid model based on quantile regression forest and Gaussian kernel (GQRF) is constructed. Quarterly dataset of KSh/USD exchange rate and macro-economic variables from 2007 to 2016 are used. The forecast horizon spans from 2013 to 2016. With a...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:50
Feature of Heart Rate Variability and Metabolic Mechanism in Female College Students with Depression
Purpose. To explore the effects of depression on cardiac autonomic nerve function and related metabolic pathways, the heart rate variability (HRV) and urinary differential metabolites were detected on the college students with depression. Methods. 12 female freshmen with depression were filtered by the Beck Depression Inventory (BDI-II) and Self-rating Depression Scale (SDS). By wearing an HRV monitoring system, time domain indexes and frequency domain indexes were measured over 24 hours. Liquid...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:50
Multivehicle Cooperative Lane Change Control Strategy for Intelligent Connected Vehicle
In order to improve the safety, stability, and efficiency of lane change operating, this paper proposes a multivehicle-coordinated strategy under the vehicle network environment. The feasibility of collaborative lane change operation is established by establishing a gain function based on the incentive model. By comparing lane change gain with lane keeping gain, whether it is feasible to perform the collaboration under current conditions can be judged. Based on the model predictive control (MPC),...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:35
Left Ventricular End Diastolic Volume and Ejection Fraction Calculation: Correlation between Three Echocardiographic Methods
Background. Left ventricular ejection fraction (LVEF) and end diastolic volume (EDV) are measured using Simpson’s biplane (SB), 3-dimensional method (3DE), and speckle tracking (STE). Comparisons between methods in routine practice are limited. Our purpose was to compare and to determine the correlations between these three methods in clinical setting. Methods. LVEF and EDV were measured by three methods in 474 consecutive patients and compared using multiple Bland–Altman (BA) plots. The correlations...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:35
Determination of the Levels of Heavy Metals and Formaldehyde in Baby Clothes in South Africa: A Case Study of Stores in the Greater Cape Town Region
Herein, we report on the determination of formaldehyde, pH, and heavy metals (Pb, As, Co, Cr, Ni, and Cd) in various baby apparel (cotton, polyester, nylon, elastane, and polyethylene) of different colours (light, medium, and dark) purchased from both high-end and low-end market stores. The concentrations of the heavy metals were determined by inductively coupled plasma (ICP) after wet digestion and also after extraction using artificial sweat for a selected range of skin-contact baby apparel. The...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:20
Application of Low-Cost Sensors for the Development of a Methodology to Design Front-End Loaders for Tractors
Tractor front-end loaders are an essential part of the equipment used on farms. At present, there are an important number of small- and medium-sized companies involved in the manufacturing of this equipment. These companies rely heavily on experience for innovative designs, as in the vast majority of cases they lack access to adequate methodology for the optimal design of new front-end loaders. The study conducted has developed a methodology to design tractor front-end loaders with a view of obtaining...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:20
Pata-Type Fixed-Point Theorems in Kaleva–Seikkala’s Type Fuzzy Metric Space
The purpose of this paper is to generalize the fixed-point theorems for Banach–Pata-type contraction and Kannan–Pata-type contraction from metric spaces to Kaleva–Seikkala’s type fuzzy metric spaces. Moreover, two examples are given for the support of our results.
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:20
Seasonal Variations of the Near-Surface Atmospheric Boundary Layer Structure in China’s Gurbantünggüt Desert
As the largest fixed and semifixed desert in China, the Gurbantünggüt Desert has a longperiod of snow in winter and the rapid growth of ephemeral plants in spring, presentingthe obvious seasonal changes in the underlying desert surface type, which could lead to the significantvariety in the near-surface boundary layer over this desert. To clarify the influence of the underlying surface change on the near-surface atmospheric boundary layer, gradient tower data and Eddy covariance data in 2017 were...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:20
High Neutrophil-to-Lymphocyte Ratio Predicts Hemorrhagic Transformation in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis
Background. The relationship between the neutrophil-to-lymphocyte ratio (NLR) and hemorrhagic transformation (HT) in acute ischemic stroke (AIS) treated with intravenous thrombolysis (IVT) remains unclear. This study assessed whether high NLR is associated with HT in this population. Methods. Data were prospectively collected for continuous patients with AIS treated with IVT and retrospectively analyzed. Clinical variables included age, sex, vascular risk factors, National Institutes of Health Stroke...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:20
Corallodiscus flabellata B.L. Burtt Extracts Stimulate Diuretic Activity and Regulate the Renal Expression of Aquaporins
Corallodiscus flabellata B. L. Burtt is a traditional Chinese medicine. Previous studies in our laboratory showed that C. flabellata alleviated symptoms of Alzheimer’s disease (AD) in a rat model of AD and increased healthy rats’ urine volume. The aims of this study were to explore the diuretic activity of different extracts from C. flabellata and to identify the underlying mechanisms of action. Different doses of a C. flabellata extract (CF-L, CF-M, and CF-H) were administered orally to male KM...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:20
1DCNN Fault Diagnosis Based on Cubic Spline Interpolation Pooling
The conventional pooling method for processing one-dimensional vibration signals may lead to certain issues, such as weakening and loss of feature information. The present study proposes the cubic spline interpolation pooling method. The method is appropriate for processing one-dimensional signals. The proposed method can transform the pooling problem into a linear fitting problem, use the cubic spline interpolation method with outstanding fitting effects, and calculate the fitting function of the...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:20
The Inhibition of Aldose Reductase Accelerates Liver Regeneration through Regulating Energy Metabolism
Objectives. Our previous study showed that aldose reductase (AR) played key roles in fatty liver ischemia-reperfusion (IR) injury by regulating inflammatory response and energy metabolism. Here, we aim to investigate the role and mechanism of AR in the regeneration of normal and fatty livers after liver surgery. Methods. The association of AR expression with liver regeneration was studied in the rat small-for-size liver transplantation model and the mice major hepatectomy and hepatic IR injury model...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
Hepatic Cyst: An Unusual Suspect of Syncope
The patient is a 75-year-old man with history of diabetes and hypertension who presented with syncope after experiencing sharp, 10/10 right flank and abdominal pain worsening over three weeks associated with decreased appetite. Physical examination revealed hepatomegaly and right lower quadrant (RUQ) tenderness, negative for peritoneal signs. Bloodwork showed leukocytosis (13 K/mcl), alkaline phosphatase (141 U/L), total bilirubin (2.0 mg/dL), and gamma-glutamyl transferase (172 U/L). Computed Tomography...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
On a Thermoelastic Laminated Timoshenko Beam: Well Posedness and Stability
In this paper, we are concerned with a linear thermoelastic laminated Timoshenko beam, where the heat conduction is given by Cattaneo’s law. We firstly prove the global well posedness of the system. For stability results, we establish exponential and polynomial stabilities by introducing a stability number .
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
The Status of Occupational Burnout and Its Influence on the Psychological Health of Factory Workers and Miners in Wulumuqi, China
The purpose of this study was to investigate the status of occupational burnout and its influence on the psychological health of factory workers and miners, in order to provide theoretical basis and reference for alleviating occupational burnout and promoting psychological health. The cross-sectional study investigated 6130 factory workers and miners with online questionnaire; the Chinese Maslach Burnout Inventory (CMBI) and Symptom Check List-90 (SCL-90) were used. In total, 6120 valid questionnaires...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
Cardiac Ameliorative Effect of Moringa oleifera Leaf Extract in High-Fat Diet-Induced Obesity in Rat Model
The consumption of a high-fat diet is linked to the development of obesity and considered a risk factor for cardiovascular diseases. The aim of this study was to evaluate the effect of the methanolic extract of Moringa oleifera leaves (MEML) on the high-fat diet- (HFD-) induced obesity and cardiac damage in rats. MEML, at a dose of 200 mg/kg/bw and 400 mg/kg/bw, was orally administrated to obese rats for 12 weeks. M. oleifera leaves were proved to be rich in nutrients and minerals. Diversity of phenolic...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
Prognostic Value of Hyperechoic Echo Halo in cN0 Papillary Thyroid Microcarcinoma and Its Correlation with Age and Gender
Purpose. To investigate the pathology and prognostic value of hyperechoic echo halo in cN0 papillary thyroid microcarcinoma (PTMC) and the relationship between age, gender, and the formation of abnormal hyperechoic echo halo and cervical lymph node metastasis. Data of 97 patients who underwent surgical treatment for the first time for single PTMC between April 2016 and March 2017 were analyzed retrospectively. The boundary status of the PTMC was determined preoperatively. Grayscale values of the...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
Developmental Timing Determines the Protective Effect of Maternal Electroacupuncture on Perinatal Nicotine Exposure-Induced Offspring Lung Phenotype
Introduction. Environmental exposure of the developing offspring to cigarette smoke or nicotine is an important predisposing factor for many chronic respiratory conditions, such as asthma, emphysema, pulmonary fibrosis, and so forth, in the exposed offspring. Studies showed that electroacupuncture (EA) applied to maternal “Zusanli” (ST36) acupoints during pregnancy and lactation protects against perinatal nicotine exposure- (PNE-) induced lung damage. However, the most effective time period, that...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
Evaluation of Mechanical Performances of Stents with 38 mm Length in Long Lesion
Objective. Single stent with 38 mm length has emerged as a potential solution for long lesion treatment using PCI. However, long stents need to come over a longer lesion length combined with a higher incidence of tortuous calcification, requiring a stent to provide superior transport and compliance and reduce elastic retraction. Here, we evaluated the mechanical performances of the existing four types of drug eluting stents with 38 mm length, which could provide guidance for clinicians to choose...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
Prediction of Side Effects Using Comprehensive Similarity Measures
Identifying the potential side effects of drugs is crucial in clinical trials in the pharmaceutical industry. The existing side effect prediction methods mainly focus on the chemical and biological properties of drugs. This study proposes a method that uses diverse information such as drug-drug interactions from DrugBank, drug-drug interactions from network, single nucleotide polymorphisms, and side effect anatomical hierarchy as well as chemical structures, indications, and targets. The proposed...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
Characteristics and Treatment of Anaphylaxis in Children Visiting a Pediatric Emergency Department in Korea
Anaphylaxis is a serious life-threatening allergic disease in children. This study is aimed at determining the characteristics of pediatric patients who experienced anaphylaxis along with treatments administered in order to determine the usefulness of tryptase level assessment as a marker of anaphylaxis in Korean children. A total of 107 patients who were diagnosed with anaphylaxis in a single pediatric emergency center over a 3-year period were included in the study. Patient clinical characteristics,...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
Identification of F5 as a Prognostic Biomarker in Patients with Gastric Cancer
Association of Coagulation factor V (F5) polymorphisms with the occurrence of many types of cancers has been widely reported, but whether it is of prognostic relevance in some cancers remain to be resolved. The RNA-sequencing dataset was downloaded from The Cancer Genome Atlas (TCGA). The potential of F5 genes to predict the survival time of gastric cancer (GC) patients was investigated using univariate and multivariate survival analysis whereas “Kaplan-Meier plotter” (KM-plotter) online tools were...
Hindawi Publishing Corporation
Fri Feb 28, 2020 13:05
Development and Validation of a Hydrophilic Interaction Liquid Chromatography Tandem Mass Spectrometry Method for the Determination of Asparagine in Human Serum
L-Asparagine (ASN) is the catalyze substrate of L-asparaginase (ASNase), which is an important drug for acute lymphoblastic leukemia (ALL) patients. The ASN level is found to be closely associated with the effectiveness of ASNase treatment. In this study, a hydrophilic interaction liquid chromatography tandem mass spectrometry (HILIC-MS/MS) method was developed for the determination of ASN in the human serum using a stable isotope-labeled internal standard (ASN-D3). Serum samples were prepared by...
Hindawi Publishing Corporation
Fri Feb 28, 2020 12:50
HSP70 Inhibition Leads to the Activation of Proteasomal System under Mild Hyperthermia Conditions in Young and Senescent Fibroblasts
Aging has been characterized with the accumulation of oxidized proteins, as a consequence of progressive decline in proteostasis capacity. Among others, proteasomal system is an efficient protein turnover complex to avoid aggregation of oxidized proteins. Heat shock protein 70 (HSP70) is another critical player that is involved in some key processes including the correct folding of misfolded proteins and targeting aggregated proteins to the proteasome for rapid degradation. The aim of this study...
Hindawi Publishing Corporation
Fri Feb 28, 2020 12:50
Multi-Period Multi-Product Supply Chain Network Design in the Competitive Environment
This paper studies a supply chain network design model with price competition. The supply chain provides multiple products for a market area in multiple periods. The model considers the location of manufacturers and retailers and assumes a probabilistic customer behavior based on an attraction function depending on both the location and the quality of the retailers. We aim to design the supply chain under the capacity constraint and maximize the supply chain profit in the competitive environment....
Hindawi Publishing Corporation
Fri Feb 28, 2020 12:50
Research on Wavelet Threshold Denoising Method for UWB Tunnel Personnel Motion Location
In the process of tunnel construction, the problems of strong sealing, inconvenient communication, and harsh environment pose a serious threat to the personal safety of construction workers. Therefore, personnel positioning technology has important application value in tunnel safety construction. A special environment for tunnel personnel positioning and the ultrawideband (UWB) positioning system are affected by personnel movement, which leads to the problem of lowering positioning accuracy. A wavelet...
Hindawi Publishing Corporation
Fri Feb 28, 2020 12:50
A Novel Analytical Solution for the Brazilian Test with Loading Arcs
This research study presents a new theoretical model to calculate the indirect tensile strength for the Brazilian disk with loading arcs, based on numerical simulations, two-dimensional elasticity theory, and Griffith failure criterion. The new expression incorporates a no uniform contact pressure distribution determined by the results of the simulations with the finite element method. A computational experiment design has been developed to test the accuracy of the predictions made with the proposed...
Hindawi Publishing Corporation
Fri Feb 28, 2020 12:50
Minimal Open Access Ileocolic Resection in Complicated Crohn’s Disease of the Terminal Ileum
The objective of this study was to evaluate the possibility to undertake an ileocolic resection in complex Crohn’s disease using a minimal open abdominal access using standard laparoscopic instruments. The incision was carried out over the previous McBurney scar, with a mean length of 6 cm. Seventy-two patients with complicated Crohn’s disease underwent IC resection in the considered period; 12 patients had a McBurney scar due to a previous appendectomy and represented the group of study. Feasibility...
Hindawi Publishing Corporation
Fri Feb 28, 2020 12:50
Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis
Background. Periampullary tumors (PT) may rarely present as acute pancreatitis (AP) or acute recurrent pancreatitis (ARP). Unlike other cases of AP and ARP, these conditions necessitate pancreaticoduodenectomy (PD), and timely diagnosis is crucial. Materials and Methods. A retrospective review of clinical, radiological, surgical, and pathological data was conducted for patients admitted to the Binzhou Medical University Hospital during the period from January 2010 to December 2017, for AP or ARP...
Hindawi Publishing Corporation
Fri Feb 28, 2020 12:50
Unusual Phenotype and Disease Trajectory in Kearns–Sayre Syndrome
Objective. To describe unusual course and unusual phenotypic features in an adult patient with Kearns–Sayre syndrome (KSS). Case Report. The patient is a 49-year-old male with KSS, diagnosed clinically upon the core features, namely, onset before the age 20 of years, pigmentary retinopathy, and ophthalmoparesis, and the complementary features, namely, elevated CSF protein, cardiac conduction defects, and cerebellar ataxia. The patient presented also with other previously described features, such...
Hindawi Publishing Corporation
Fri Feb 28, 2020 12:50
Calcinosis Cutis Associated with Chronic Sclerodermoid Graft versus Host Disease: A Case and Review of the Literature
We present a rare case of calcinosis cutis associated with chronic sclerodermoid graft versus host disease in a 59-year-old male, 13 years following allogenic bone marrow transplantation. The etiology of calcification was thought to be dystrophic. Further research is needed to understand the link between calcinosis cutis and chronic sclerodermoid graft versus host disease to assist with selecting appropriate management for these patients.
Hindawi Publishing Corporation
Fri Feb 28, 2020 12:50

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