To determine the effects of ACEIs on arterial stiffness, a meta-analysis of randomized controlled trials was conducted. Relevant articles that investigated the effects of ACEIs on arterial stiffness from PubMed, Embase, and the Cochrane library from inception to September 2018 were systematically retrieved. The investigated outcomes included brachial-ankle pulse wave velocity (ba-PWV) and carotid-femoral PWV (cf-PWV) by using weighted mean differences (WMDs) and 95% confidence intervals (CIs) with...
Bone loss is one of the emerging extra-articular manifestations of rheumatoid arthritis. TNF-α is the main inflammatory cytokine that can directly increase bone resorption. However, its role in bone formation is still unknown, especially related to secreted frizzled-related protein 1 (SFRP-1), an osteoblast inhibitor. This study examines the correlation between TNF-α and SFRP-1, with a bone turn over marker (CTX and P1NP). This is a cross-sectional study with 38 subjects of premenopausal female patients...
This study examines the impacts of relevant factors (climatic and nonclimatic) on the monthly electricity consumption (MEC) in four major cities in Niger using simple multiple linear regressions (MLRs). Parameters such GDP/capita, air temperature (mean), relative humidity (RH), wind speed (WSP), solar radiation (SR), precipitation, and clearness index (K) are used. In addition, two heat indices, heat index (HI) and discomfort index (DI) are calculated to take into account the impacts of high humidity...
Over 600 million people living in sub-Saharan Africa do not have access to electricity. Modern healthcare services, including vaccine refrigeration, which require electricity are therefore lacking in such energy-deprived communities. In this work, analysis has been conducted on how electricity access can help improve healthcare service delivery and rural development, with a case study on 3 different off-grid solar photovoltaic (PV) systems in community-based health planning and services (CHPS) in...
Fifth generation (5G) mobile communications have many aspects of services, including the one by the technology of Internet of things (IoT). To support the diverse service types of IoT applications, heterogeneous requirements for massive connectivity and low latency are mandatory. In this paper, service group based filtered orthogonal frequency division multiplexing (FOFDM) combined with interleaved division multiple access (IDMA), i.e., FOFDM-IDMA, is proposed in order to simultaneously support massive...
External gas-assisted injection molding (EGAIM) has been used to reduce the sink marks of amorphous polymer products, but that of crystalline polymer products has not yet been reported. EGAIM of a crystalline polymer product was investigated in this study, and the influences of process parameters on the sink marks were discussed based on experiments. An isotactic polypropylene (iPP) product was fabricated by EGAIM under different process conditions. A uniform design was applied as an experimental...
Thermoplastic elastomer (TPE) is a kind of new automotive interior material with high elasticity and strength. Traditional TPE materials were difficult to meet the new requirements of large-scale automotive interior parts with complex shape. In this study, the TPE material was prepared using different mass ratios with homopolymer polypropylene (PP), styrene-ethylene/butene-styrene copolymer (SEBS), naphthene oil (NO), magnesium stearate (MGST), and polytetrafluoroethylene (PTFE). A quality-prediction...
Two hundred customers were purposively selected from two study areas (market, residence) in Addis Ababa to assess customer’s behavior and perception towards packaged water. The sampling and data collection process of the study followed systematic analysis of Theory Planned Behavior. The average monthly income of respondents of this study lay between 5000 ($175) and 10000 ($350) Eth Birr. The primary customer information sources were television and radio. Residence place customers were more concerned...
In order to prevent the overfitting and improve the generalization performance of Extreme Learning Machine (ELM), a new regularization method, Biased DropConnect, and a new regularized ELM using the Biased DropConnect and Biased Dropout (BD-ELM) are both proposed in this paper. Like the Biased Dropout to hidden nodes, the Biased DropConnect can utilize the difference of connection weights to keep more information of network after dropping. The regular Dropout and DropConnect set the connection weights...
Background. Septic arthritis of the sacroiliac joint (SI-joint) is a rare and often delayed diagnosis. Management usually consists of intravenous antibiotics and debridement of infected tissue. However, very few reports consider the management of the secondary instability of the sacroiliac joint. Case Presentation. We report a case of a 16-year-old girl diagnosed with S. aureus pyogenic sacroiliitis who benefited from aggressive surgical debridement and primary arthrodesis for infection-related SI-joint...
Cystic echinococcosis (CE) is a neglected helminthic disease and major public health problem in several regions of the world. The zoonosis is caused by the larval stage of different cestode species belonging to the genus Echinococcus. CE can affect any organ with the liver and lungs being most commonly involved. The brain is involved in less than 2% of the cases. We report a case of a CE1 echinococcal cyst of the brain in an Iranian patient.
Left ventricular noncompaction (LVNC) is described as a cardiomyopathy with an increase in left ventricle trabeculations and recesses. We report a rare case of persistent pregnancy-acquired LVNC cardiomyopathy and review the anesthetic peripartum management strategies. A 33-year-old parturient was followed closely by the high-risk obstetric service for her second pregnancy. She had an unresolved LVNC cardiomyopathy that was diagnosed during her first pregnancy for which she had a caesarean section....
The prevalence of diabetes and its associated complications is increasing throughout the decades. Promising diabetes medications were introduced to the market including GLP-1 agonists, DPP-4 inhibitors, and SGLT2 inhibitors aiming to target these complications. The literature lacks sufficient data regarding these new medications and their influence on nephropathy, retinopathy, and neuropathy. This review expands on the major results of effects of the 3 drug classes on microvascular complications....
We report the case of painful snapping pes syndrome caused by the gracilis tendon. A 26-year-old man presented with acute right knee pain and restricted extension. Although snapping could not be reproduced due to severe pain, the snapping of the gracilis tendon could be specifically diagnosed using ultrasonography and lidocaine injection. Because of the failure of conservative treatment, surgery was performed. The distal attachment of the gracilis tendon was released, and the symptom disappeared...
The present work is devoted to the numerical study of steady and laminar mixed convection of nanofluid (water nanoparticles) in a horizontal channel provided with sources of heat at constant temperature, which simulate hot electronic components. The transport equations for continuity, momentum, and energy are solved with finite volume approach using the SIMPLE algorithm. The effective thermal conductivity and the dynamic viscosity of the nanofluid are calculated using, respectively, the Maxwell-Garnett...
In view of the problems of ordinary rubber seals, such as high- and low-temperature resistance, easy aging, and insufficient load-bearing performance, O-type metal rubber seals with large ring-to-diameter ratio were prepared by the cold stamping method using stainless steel wire as raw material. The effects of heat treatment and porosity on the compression and tensile properties of test samples were investigated. Under uniaxial compression testing, it was found that the test sample had typical hysteresis...
Vesicular glutamate transporter type 2 (VGLUT2) is known to play an important role in mediating heat hyperalgesia induced by inflammation. However, the underlying mechanism for this activity is poorly understood. Cyclin-dependent kinase 5 (Cdk5), serving as a key regulator in modulating release of glutamate, acted a key player in the formation of heat hyperalgesia of inflammatory pain. However, it remains unknown whether there is a bridge between Cdk5 and VGLUT2 for mediating inflammatory pain. Therefore,...
This case report is aimed at describing a flapless, minimally invasive clinical crown lengthening with an osteotomy performed using a piezoelectric ultrasound. A female patient complained about the amount of gum that was exposed when she smiled, which caused aesthetic discomfort. After a clinical examination, it was confirmed that the patient had excessive gum exposure in the upper arch of the dental region for teeth 14 to 24 when she smiled. The tomographic exam showed that bone tissue was at the...
There are only a few cases of steroid cell tumours that have been described in the literature. Here, we present an exceptionally rare case of a steroid cell tumour arising from the ovary in early pregnancy.
Construction worker safety and safety training continue to be the main issues in the construction industry. As a means of improving construction worker safety, this study focuses on safety training at an actual construction worksite. In order to promote safety awareness among workers, it is imperative to develop more effective safety training. This study examined safety training as a method of improving construction worker safety, focusing on the effectiveness of the instructional delivery method....
Mustard aphid (Lipaphis erysimi) and English grain aphid (Sitobion avenae) are among the most important pests in mustard and wheat fields in Nepal. Biocide Manic (Metarhizium anisopliae a.i. = 1 × 109 spores/ml) at 3 ml/l water, Agri Sakti (Beauveria bassiana a.i. = 1 × 109 spores/ml) at 3.3 ml/l water, Varunastra (Verticillium lecanii spores 2% aqueous suspension, 2 × 108 CFU/ml) at 6 ml/l water, Mahastra (Bacillus thuringiensis var. kurstaki 0.5% wettable powder) at 6 g/l water, Neemraj Super (Azadirachitin...
This paper presents a numerical investigation on the 2D uniaxial die compaction of TiC-316L stainless steel (abbreviated by 316L) composite powders by the multiparticle finite element method (MPFEM). The effects of TiC-316L particle size ratios, TiC contents, and initial packing structures on the compaction process are systematically characterized and analyzed from macroscale and particulate scale. Numerical results show that different initial packing structures have significant impacts on the densification...
Natural plants are considered as a huge treasure for anticancer. Amomum tsaoko, a plant of Zingiberaceae, is used widely as a food and traditional medicine in East Asia. In previous studies, Amomum tsaoko has antitumor effect on liver cancer cells, but the mechanism is not clear. Here, we demonstrated that ethanol extract from Amomum tsaoko (At-EE) could inhibit ovarian cancer and decrease angiogenesis in vivo. At-EE did not influence vascular endothelial cells directly, but decreased IL-6 and VEGF...
Integrated-starter-generator (ISG) motors are a key part of new-energy vehicle dynamic systems. To more efficiently design higher-performance permanent magnet ISG motors, we proposed a multiphysical-domain integrated design method by designing the electromagnetism and thermal performance of motors and the mechanical structure strength of rotors together. A 48-slot and 8-pole oil-cooled permanent magnet ISG motor was designed by using this method and simulated via the finite element method. Also,...
Xuebijing injection is a Chinese herb compound to treat sepsis in China, but it contains many different kinds of components, and each component may have different effects in treating sepsis. The present study was performed to investigate the effect of three ingredients of Xuebijing, safflor yellow A (SYA), hydroxysafflor yellow A (HSYA), and anhydrosafflor yellow B (AHSYB), in lipopolysaccharide- (LPS-) induced acute lung injury (ALI). LPS (10 mg/kg) was injected intratracheally to induce acute lung...
Aims. To investigate the effect of preoperative HbA1c levels on the postoperative outcomes of coronary artery disease surgery in diabetic and nondiabetic patients. Methods and Results. The MEDLINE (via PubMed), Cochrane Library, Web of Science, Embase, Wanfang Data, China National Knowledge Infrastructure (CNKI), and Chinese Biology Medicine (CBM) databases were used to search the effects of different preoperative HbA1c levels on the postoperative outcomes of coronary artery disease surgical treatment...
Short-term precipitation forecast in local areas based on radar reflectance images has become a hot spot issue in the meteorological field, which has an important impact on daily life. Recently, deep learning techniques have been applied to this field, and the effect is promoted remarkably compared with traditional methods. However, existing deep learning-based methods have not considered the problem that different areas and channels exert different influence on precipitation. In this paper, we propose...
Research on the Estimation Method of the Stiffness Degeneration Index of Reinforced Concrete Members
Based on variable amplitude displacement cycle tests of 24 reinforced concrete members with different reinforcement conditions, the stiffness degradation index was proposed to describe the damage. The relationship between the stiffness degradation index, the displacement history, and the cumulative energy dissipation was studied; on this basis, an estimation method for the stiffness degradation index was proposed. By comparing the experimental values and estimated values of the stiffness degradation...
Precast components manufacturer generally operates under limited production capacity and produces products of one order which may delay another. This paper develops a precast component order acceptance and scheduling model that aims to maximize the total profit in a stochastic multiple orders environment. In that model, the increasing of the overall profit of the precast component manufacturer is achieved by using a heuristic algorithm and a dynamic order acceptance heuristic. Results of numerical...
In order to study the influence of the circumferential placement position of the guide vane on the flow field and stress-strain of a nuclear reactor coolant pump, the CAP1400 nuclear reactor coolant pump is taken as the research object. Based on numerical calculation and test results, the influence of circumferential placement position of the guide vane on the performance of the nuclear reactor coolant pump and stress-strain of guide vanes are analyzed by the unidirectional fluid-solid coupling method....
Although there are some studies on the risk management of logistics service supply chain (LSSC), we still know little about the effects of risk evolution and interactional mechanism of subjects in different urgent scenarios of logistics service supply chain from a micro perspective. Based on the structures of the LSSC, this study thus analyzed the risk evolution and the main actors’ reactions in the LSSC, including categorizing the urgent scenarios, analyzing their impacts on the diffusion intensity...
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer-related death. Among these, lung adenocarcinoma (LUAD) accounts for most cases. Due to the improvement of precision medicine based on molecular characterization, the treatment of LUAD underwent significant changes. With these changes, the prognosis of LUAD becomes diverse. N6-methyladenosine (m6A) is the most predominant modification in mRNAs, which has been a research hotspot in the field of oncology. Nevertheless,...
Background. No previous study has investigated the adherence rate of North-African pulmonologists to the 2017-GOLD PTGs. Aims. To investigate the adherence rate of Tunisian pulmonologists to the 2017-GOLD PTGs and to identify the barriers to their adherence. Methods. This was a cohort study involving clinically stable COPD patients who presented to a pulmonology outpatient consultation. The patients were classified as having been appropriately and inappropriately (over- or undertreatment) treated...
Silver nanowires (AgNWs) have a broad range of applications including nanoelectronics, energy conversion, health care, solar cells, touch screens, sensors and biosensors, wearable electronics, and drug delivery systems. As their characteristics depend strongly on their size and morphology, it is essential to find the optimal and most cost-effective synthesis method with precise control over the size and morphology of the wires. Various methods for AgNW synthesis have been reported along with process...
Background. No clear guidelines exist for the management of phlegmasia cerulea dolens. This case report shows how a hybrid approach might be successful. It also shows how rare pathologies can combine to create a life- and limb-threatening condition. Case Presentation. A 75-year-old man, known for nephrotic syndrome currently under investigation, presented to the emergency department with a 24-hour history of left leg swelling followed by intense pain. The left lower limb showed a phlegmasia cerulean...
Germ cell tumors account for 15% of anterior mediastinum tumors. Fistulas are abnormal communications between two surfaces covered by the epithelium. A fistula can occur between the bronchial tree and the adjacent anatomical structures secondary to variable etiologies. The main clinical manifestations of bronchial fistulas include hemoptysis, purulent cough, and pneumonia, which might threaten the patient’s life. Diagnosis can be established with computed tomography, which shows direct and indirect...
Associations between neuropsychotic changes and oncologic disease are often described as late-onset symptoms, secondary to the instituted treatment. However, neurocognitive symptoms as a clinical manifestation of adnexal tumors are still little discussed, despite the importance of these in the gynecology practice. In this article, we present a case of adnexal mass whose first clinical manifestations were neuropsychiatric alterations. Such changes led the patient to seek our health service, and after...
Previous studies suggest that passive motion exercise (PME) may be useful for overcoming exercise limitations associated with a sedentary lifestyle, orthopedic disorders, and various other debilitating conditions. Negative mood response is one of the factors that limit a person’s ability to exercise. Therefore, this study tests the hypothesis that the mood response associated with PME is not different than the mood response associated with active motion exercise (AME). Eight women and seven men participated...
An experimental study of a rock-like material containing a preexisting fissure subjected to loading and unloading triaxial compression is carried out, and the results show that the mechanical characteristics of the rock-like specimen depend heavily on the loading paths and the inclination of the fissure. The triaxial loading experiment results show that the failure strength linearly increases, while the residual strength linearly decreases with increasing inclination. Furthermore, specimens subjected...
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