This review of the efficacy of 3 caries removal strategies (complete, selective and stepwise) in primary teeth included 8 RCTs suggesting a lower risk of pulp exposure with selective and stepwise approaches. The post Primary teeth: Efficacy of 3 caries removal strategies appeared first on National Elf Service.
08:02
Abstract Background Shoulder impingement syndrome is one of the most common causes of shoulder pain, accounting for approximately 30% of all shoulder pain. Approximately 35% of patients with shoulder impingement syndrome are refractory to conservative treatment. For patients who fail conservative treatment, there is no established treatment to successfully treat their chronic pain. Prior randomized control trials have demonstrated...
02:00
Abstract Background Antipsychotic drug-induced weight gain puts individuals with schizophrenia at increased cardiometabolic risk. As a potential intervention for this problem, we describe the theoretical background and a protocol for a feasibility randomised controlled trial (RCT) of approach bias modification (ABM) training combined with real versus sham (placebo) transcranial direct current stimulation (tDCS). The primary aim of...
02:00
Abstract Objective We aimed to assess the patient experience of informed consent (IC) during acute myocardial infarction (AMI) in a sub-study of the VALIDATE-SWEDEHEART trial. The original trial compared two anticoagulant agents in patients undergoing coronary intervention. A witnessed oral IC was required prior to randomization in patients with ST-segment elevation myocardial infarction, which was subsequently complemented with...
02:00
Abstract Background The aim of this study is to demonstrate that capecitabine metronomic chemotherapy is non-inferior to capecitabine conventional chemotherapy as maintenance treatment, in patients who have responded to 16–18 weeks first-line chemotherapy in metastatic colorectal cancer (mCRC). Methods The study design is a prospective, randomized,...
02:00
Abstract Background Complications of preterm birth cause more than 1 million deaths each year, mostly within the first day after birth (47%) and before full post-natal stabilisation. Kangaroo mother care (KMC), provided as continuous skin-to-skin contact for 18 h per day to fully stabilised neonates ≤ 2000 g, reduces mortality by 36–51% at discharge or term-corrected age compared with incubator care. The mortality effect of starting...
02:00
After publication of our article [1] the authors have notified us that one of the names has been incorrectly spelled.
02:00
Abstract Background There are difficulties in carrying out research in low-income urban communities, but the methodological challenges and suggestions on how to deal with them are often undocumented. The aims of this study are to describe the challenges of recruiting and enrolling low-income pregnant women with periodontitis to a clinical trial on vitamin D/calcium milk fortification and periodontal therapy and also to describe the...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1805: Inhibitory Plasticity: From Molecules to Computation and Beyond International Journal of Molecular Sciences doi: 10.3390/ijms21051805 Authors: Daniela Gandolfi Albertino Bigiani Carlo Adolfo Porro Jonathan Mapelli Synaptic plasticity is the cellular and molecular counterpart of learning and memory and, since its first discovery, the analysis of the mechanisms underlying long-term changes of synaptic strength has been almost exclusively focused...
02:00
IJMS, Vol. 21, Pages 1804: Reperfusion Arrhythmias Increase after Superior Cervical Ganglionectomy Due to Conduction Disorders and Changes in Repolarization International Journal of Molecular Sciences doi: 10.3390/ijms21051804 Authors: Natalia Jorgelina Prado Estela Maris Muñoz Luz Estefanía Farias Altamirano Francisco Aguiar Amira Zulma Ponce Zumino Francisco Javier Sánchez Roberto Miguel Miatello Esther Pueyo Emiliano Raúl Diez Pharmacological concentrations...
02:00
IJMS, Vol. 21, Pages 1802: Secretome of Senescent Adipose-Derived Mesenchymal Stem Cells Negatively Regulates Angiogenesis International Journal of Molecular Sciences doi: 10.3390/ijms21051802 Authors: Ratushnyy Ezdakova Buravkova Nowadays, paracrine regulation is considered as a major tool of mesenchymal stem cell (MSC) involvement in tissue repair and renewal in adults. Aging results in alteration of tissue homeostasis including neovascularization. In this study, we...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1801: Proregenerative Activity of IL-33 in Gastric Tissue Cells Undergoing Helicobacter pylori-Induced Apoptosis International Journal of Molecular Sciences doi: 10.3390/ijms21051801 Authors: Gonciarz Krupa Chmiela Interleukin (IL)-33 is a proinflammatory mediator that alerts the host immune system to disorders in tissue homeostasis. Aim. To understand the role of IL-33 in modulating gastric tissue cell growth affected by Helicobacter pylori (H. pylori)....
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1799: Development of pH-Responsive Biopolymeric Nanocapsule for Antibacterial Essential Oils International Journal of Molecular Sciences doi: 10.3390/ijms21051799 Authors: Skalickova Aulichova Venusova Skladanka Horky It is generally believed that antibacterial essential oils have the potential to become one of the alternatives in preventing diarrheal diseases of monogastric animals. The disadvantage is their low efficiency per oral due...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1800: Genome-Wide Detection of Key Genes and Epigenetic Markers for Chicken Fatty Liver International Journal of Molecular Sciences doi: 10.3390/ijms21051800 Authors: Tan Liu Xing Zhang Li Zheng Zhao Wen Chickens are one of the most important sources of meat worldwide, and the occurrence of fatty liver syndrome (FLS) is closely related to production efficiency. However, the potential mechanism of FLS remains poorly understood....
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1796: Opposing Roles of FoxA1 and FoxA3 in Intrahepatic Cholangiocarcinoma Progression International Journal of Molecular Sciences doi: 10.3390/ijms21051796 Authors: Thanan Kaewlert Sakonsinsiri Chaiprasert Armartmuntree Muengsaen Techasen Klanrit Lert-itthiporn Pinlaor Pairojkul Cholangiocarcinoma (CCA), a malignancy of biliary epithelium, is related to liver stem cell deregulation. FoxAs are a group of transcription...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1794: Exposure to Mono-n-Butyl Phthalate in Women with Endometriosis and Its Association with the Biological Effects on Human Granulosa Cells International Journal of Molecular Sciences doi: 10.3390/ijms21051794 Authors: Chou Chen Chen Chang Lai Tzeng To study the association between urinary phthalate metabolite levels, endometriosis, and their effects on human granulosa cells, we recruited patients who underwent laparoscopy to confirm...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1793: Solvent Dependence of the Rheological Properties in Hydrogel Magnetorheological Plastomer International Journal of Molecular Sciences doi: 10.3390/ijms21051793 Authors: Hapipi Mazlan Ubaidillah Aziz Khairi Nordin Nazmi Chemically crosslinked hydrogel magnetorheological (MR) plastomer (MRP) embeddedwith carbonyl iron particles (CIPs) exhibits excellent magnetic performance (MR effect) in thepresence of external stimuli especially...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1797: Combined Dendritic and Axonal Deterioration Are Responsible for Motoneuronopathy in Patient-Derived Neuronal Cell Models of Chorea-Acanthocytosis International Journal of Molecular Sciences doi: 10.3390/ijms21051797 Authors: Glaß Neumann Pal Reinhardt Storch Sterneckert Hermann Chorea acanthocytosis (ChAc), an ultra-rare devastating neurodegenerative disease, is caused by mutations in the VPS13A gene, which encodes for the...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1795: Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice International Journal of Molecular Sciences doi: 10.3390/ijms21051795 Authors: Nahomi Nam Rankenberg Rakete Houck Johnson Stankowska Pantcheva MacLean Nagaraj Background: Glaucoma is an optic neuropathy and involves the progressive degeneration of retinal ganglion cells (RGCs), which leads to blindness in patients....
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1798: Arginine Derivatives in Cerebrovascular Diseases: Mechanisms and Clinical Implications International Journal of Molecular Sciences doi: 10.3390/ijms21051798 Authors: Gerrit M. Grosse Edzard Schwedhelm Hans Worthmann Chi-un Choe The amino acid L-arginine serves as substrate for the nitric oxide synthase which is crucial in vascular function and disease. Derivatives of arginine, such as asymmetric (ADMA) and symmetric dimethylarginine (SDMA),...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1789: Integrated Transcriptomic and Un-Targeted Metabolomics Analysis Reveals Mulberry Fruit (Morus atropurpurea) in Response to Sclerotiniose Pathogen Ciboria shiraiana Infection International Journal of Molecular Sciences doi: 10.3390/ijms21051789 Authors: Bao Gao Zheng Zhao Zhang Jiao Su Qian Mulberry sclerotiniose caused by Ciboria shiraiana is a devastating disease of mulberry (Morus alba L.) fruit in Northwest China....
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1792: Research Advances of Beneficial Microbiota Associated with Crop Plants International Journal of Molecular Sciences doi: 10.3390/ijms21051792 Authors: Lei Tian Xiaolong Lin Jun Tian Li Ji Yalin Chen Lam-Son Phan Tran Chunjie Tian Plants are associated with hundreds of thousands of microbes that are present outside on the surfaces or colonizing inside plant organs, such as leaves and roots. Plant-associated microbiota plays a vital...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1790: Manipulation of Ascorbate Biosynthetic, Recycling, and Regulatory Pathways for Improved Abiotic Stress Tolerance in Plants International Journal of Molecular Sciences doi: 10.3390/ijms21051790 Authors: Ronan C. Broad Julien P. Bonneau Roger P. Hellens Alexander A.T. Johnson Abiotic stresses, such as drought, salinity, and extreme temperatures, are major limiting factors in global crop productivity and are predicted to be exacerbated by climate...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1788: Altered Cofactor Preference of Thermostable StDAPDH by a Single Mutation at K159 International Journal of Molecular Sciences doi: 10.3390/ijms21051788 Authors: Gao Ma Song Sun Li Liu D-amino acid production from 2-keto acid by reductive amination is an attractive pathway because of its high yield and environmental safety. StDAPDH, a meso-diaminopimelate dehydrogenase (meso-DAPDH) from Symbiobacterium thermophilum, was the first...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1791: Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs International Journal of Molecular Sciences doi: 10.3390/ijms21051791 Authors: Darcy C. Engelhart Jeffry C. Granados Da Shi Milton H. Saier Jr. Michael E. Baker Ruben Abagyan Sanjay K. Nigam The SLC22 family of OATs, OCTs, and OCTNs is emerging as a central hub of endogenous physiology. Despite often being referred to as “drug”...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1784: New Perspectives Related to the Bioluminescent System in Dinoflagellates: Pyrocystis lunula, a Case Study International Journal of Molecular Sciences doi: 10.3390/ijms21051784 Authors: Carlos Fajardo Marcos De Donato Hectorina Rodulfo Gonzalo Martinez-Rodriguez Benjamin Costas Juan Miguel Mancera Francisco Javier Fernandez-Acero Pyrocystis lunula is considered a model organism due to its bioluminescence capacity linked to circadian...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1786: Using Serum Amino Acids to Predict Traumatic Brain Injury: A Systematic Approach to Utilize Multiple Biomarkers International Journal of Molecular Sciences doi: 10.3390/ijms21051786 Authors: Marzieh Hajiaghamemar Todd Kilbaugh Kristy B. Arbogast Christina L. Master Susan S. Margulies Traumatic brain injury (TBI) can cause biochemical and metabolomic alterations in the brain tissue and serum. These alterations can be used for diagnosis and...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1785: (R)-(+)-β-Citronellol and (S)-(−)-β-Citronellol in Combination with Amphotericin B against Candida Spp. International Journal of Molecular Sciences doi: 10.3390/ijms21051785 Authors: Daniele Silva Hermes Diniz-Neto Laísa Cordeiro Maria Silva-Neta Shellygton Silva Francisco Andrade-Júnior Maria Leite Jefferson Nóbrega Maria Morais Juliana Souza Lyvia Rosa Thamara Melo Helivaldo Souza Aleson Sousa Gregório...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1787: Modulation of Energy Metabolism Is Important for Low-Oxygen Stress Adaptation in Brassicaceae Species International Journal of Molecular Sciences doi: 10.3390/ijms21051787 Authors: Ji-Hye Hwang Si-in Yu Byeong-ha Lee Dong-Hee Lee Low-oxygen stress, mainly caused by soil flooding, is a serious abiotic stress affecting crop productivity worldwide. To understand the mechanisms of low-oxygen stress responses and adaptation of plants, we characterized...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1782: The Complex Network between MYC Oncogene and microRNAs in Gastric Cancer: An Overview International Journal of Molecular Sciences doi: 10.3390/ijms21051782 Authors: Ana Carolina Anauate Mariana Ferreira Leal Danielle Queiroz Calcagno Carolina Oliveira Gigek Bruno Takao Real Karia Fernanda Wisnieski Leonardo Caires dos Santos Elizabeth Suchi Chen Rommel Rodríguez Burbano Marília Arruda Cardoso Smith Despite the advancements...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1781: Comparative Root Transcriptomics Provide Insights into Drought Adaptation Strategies in Chickpea (Cicer arietinum L.) International Journal of Molecular Sciences doi: 10.3390/ijms21051781 Authors: Vijay Bhaskarla Gaurav Zinta Rebecca Ford Mukesh Jain Rajeev K. Varshney Nitin Mantri Drought adversely affects crop production across the globe. The root system immensely contributes to water management and the adaptability of plants to drought...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1779: Upregulation of CD20 Positive B-Cells and B-Cell Aggregates in the Tumor Infiltration Zone is Associated with Better Survival of Patients with Pancreatic Ductal Adenocarcinoma International Journal of Molecular Sciences doi: 10.3390/ijms21051779 Authors: Maximilian Brunner Katharina Maier Petra Rümmele Anne Jacobsen Susanne Merkel Alan Benard Christian Krautz Stephan Kersting Robert Grützmann Georg F. Weber Patients...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1783: UL36 Encoded by Marek’s Disease Virus Exhibits Linkage-Specific Deubiquitinase Activity International Journal of Molecular Sciences doi: 10.3390/ijms21051783 Authors: Junyan Lin Yongxing Ai Hongda Zhou Yan Lv Menghan Wang Jiacui Xu Cong Yu Huanmin Zhang Mengyun Wang (1) Background: Deubiquitinase (DUB) regulates various important cellular processes via reversing the protein ubiquitination. The N-terminal fragment of a giant...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1780: Oxylipin Profiles as Functional Characteristics of Acute Inflammatory Responses in Astrocytes Pre-Treated with IL-4, IL-10, or LPS International Journal of Molecular Sciences doi: 10.3390/ijms21051780 Authors: Dmitry V. Chistyakov Gleb E. Gavrish Sergei V. Goriainov Viktor V. Chistyakov Alina A. Astakhova Nadezda V. Azbukina Marina G. Sergeeva Functional phenotypes, which cells can acquire depending on the microenvironment, are...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1767: Counteracting Radio-Resistance Using the Optimization of Radiotherapy International Journal of Molecular Sciences doi: 10.3390/ijms21051767 Authors: François Chevalier Radiotherapy is an essential component of cancer therapy and remains one of the most (cost-) effective treatment options available [...]
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1775: The Role of NFκB in Healthy and Preeclamptic Placenta: Trophoblasts in the Spotlight International Journal of Molecular Sciences doi: 10.3390/ijms21051775 Authors: Brooke Armistead Leena Kadam Sascha Drewlo Hamid-Reza Kohan-Ghadr The NFκB protein family regulates numerous pathways within the cell—including inflammation, hypoxia, angiogenesis and oxidative stress—all of which are implicated in placental development....
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1776: A Possible Link of Genetic Variations in ER/IGF1R Pathway and Risk of Melanoma International Journal of Molecular Sciences doi: 10.3390/ijms21051776 Authors: Tze-An Yuan Vandy Yourk Ali Farhat Katherine L. Guo Angela Garcia Frank L. Meyskens Feng Liu-Smith The mechanism of gender disparity in cutaneous melanoma incidence remains unclear. Steroid hormones including estrogens have long been implicated in the course of melanoma, but...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1778: A Systematic Test of Receptor Binding Kinetics for Ligands in Tumor Necrosis Factor Superfamily by Computational Simulations International Journal of Molecular Sciences doi: 10.3390/ijms21051778 Authors: Zhaoqian Su Yinghao Wu Ligands in the tumor necrosis factor (TNF) superfamily are one major class of cytokines that bind to their corresponding receptors in the tumor necrosis factor receptor (TNFR) superfamily and initiate multiple intracellular signaling...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1777: Synthetic HDL Nanoparticles Delivering Docetaxel and CpG for Chemoimmunotherapy of Colon Adenocarcinoma International Journal of Molecular Sciences doi: 10.3390/ijms21051777 Authors: Lindsay M. Scheetz Minzhi Yu Dan Li María G. Castro James J. Moon Anna Schwendeman Colon carcinomas comprise over two-thirds of all colorectal cancers with an overall 5-year survival rate of 64%, which rapidly decreases to 14% when the cancer becomes metastatic....
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1774: The Arabidopsis GPI-Anchored LTPg5 Encoded by At3g22600 Has a Role in Resistance against a Diverse Range of Pathogens International Journal of Molecular Sciences doi: 10.3390/ijms21051774 Authors: Muhammad Amjad Ali Amjad Abbas Farrukh Azeem Mahpara Shahzadi Holger Bohlmann Arabidopsis contains 34 genes for glycosylphosphatidylinositol (GPI)-anchored LTPg proteins. A motif analysis has placed these into four groups. With one exception,...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1769: EPA is More Effective than DHA to Improve Depression-Like Behavior, Glia Cell Dysfunction and Hippcampal Apoptosis Signaling in a Chronic Stress-Induced Rat Model of Depression International Journal of Molecular Sciences doi: 10.3390/ijms21051769 Authors: Zhilan Peng Cai Zhang Ling Yan Yongping Zhang Zhiyou Yang Jiajia Wang Cai Song Clinical evidence indicated that eicosapentaenoic acid (EPA) was more effective than docosahexaenoic...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1772: PINK1/Parkin Mediated Mitophagy, Ca2+ Signalling, and ER–Mitochondria Contacts in Parkinson’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms21051772 Authors: Lucia Barazzuol Flavia Giamogante Marisa Brini Tito Calì Endoplasmic reticulum (ER)–mitochondria contact sites are critical structures for cellular function. They are implicated in a plethora of cellular processes, including Ca2+ signalling and mitophagy,...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1771: Homocysteine Disrupts Balance between MMP-9 and Its Tissue Inhibitor in Diabetic Retinopathy: The Role of DNA Methylation International Journal of Molecular Sciences doi: 10.3390/ijms21051771 Authors: Ghulam Mohammad Renu A. Kowluru High homocysteine is routinely observed in diabetic patients, and this non-protein amino acid is considered as an independent risk factor for diabetic retinopathy. Homocysteine biosynthesis from methionine forms S-adenosyl...
Thu Mar 05, 2020 02:00
IJMS, Vol. 21, Pages 1773: Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling International Journal of Molecular Sciences doi: 10.3390/ijms21051773 Authors: Chi-Hung R. Or Chiao-Wen Huang Ching-Chin Chang You-Chen Lai Yi-Ju Chen Chia-Che Chang Colorectal cancer (CRC) is a highly prevailing cancer and the fourth leading cause of cancer mortality worldwide. Aberrant...
Thu Mar 05, 2020 02:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου