Related ArticlesComputed Tomography Angiography findings can predict massive bleeding in head and neck tumours. Eur J Radiol. 2020 Feb 21;125:108910 Authors: Cannavale A, Corona M, Nardis P, De Rubeis G, Cannavale G, Santoni M, De Gyurgyokai SZ, Catalano C, Bezzi M Abstract PURPOSE: The aim of our study was to assess CT angiography findings of head and neck tumours in predicting carotid blow out syndrome (CBS). METHOD: We retrospectively...
Related ArticlesCurrent management of stage IV nasopharyngeal carcinoma without distant metastasis. Cancer Treat Rev. 2020 Feb 21;85:101995 Authors: Ng WT, Corry J, Langendijk JA, Lee AWM, Mäkitie A, Mendenhall WM, Rinaldo A, Rodrigo JP, Saba NF, Smee R, Strojan P, Suárez C, Vermorken JB, Ferlito A Abstract Up to one in four patients with nasopharyngeal carcinoma present with non-metastatic stage IV disease (i.e. T4 or N3). Distinct failure patterns...
Related ArticlesReal-time fMRI feedback impacts brain activation, results in auditory hallucinations reduction: Part 1: Superior temporal gyrus -Preliminary evidence. Psychiatry Res. 2020 Feb 10;286:112862 Authors: Okano K, Bauer CCC, Ghosh SS, Lee YJ, Melero H, de Los Angeles C, Nestor PG, Del Re EC, Northoff G, Whitfield-Gabrieli S, Niznikiewicz MA Abstract Auditory hallucinations (AH) are one of the core symptoms of schizophrenia (SZ) and constitute...
Related ArticlesCommon fibrin deposition and tissue plasminogen activator downregulation in nasal polyps with distinct inflammatory endotypes. J Allergy Clin Immunol. 2020 Feb 26;: Authors: Chen CL, Yao Y, Pan L, Hu ST, Ma J, Wang ZC, Kern RC, Schleimer RP, Liu Z Abstract CAPSULE SUMMARY: tPA downregulation induced by both type 2 and type 1 cytokines and resulting enhanced fibrin deposition may be a common mechanism for the edema formation in nasal...
Related ArticlesSignificance of examined lymph nodes number and metastatic lymph nodes ratio in overall survival and adjuvant treatment decision in resected laryngeal carcinoma. Cancer Med. 2020 Feb 29;: Authors: Zhu X, Zhao M, Zhou L, Zhang M, Cao P, Tao L Abstract OBJECTIVE: The value of adjuvant therapy in resected laryngeal cancer remains controversial. This large SEER-based cohort study aimed to investigate the existing parameters of lymph node...
Related ArticlesIron Sucrose as MRI Contrast Agent in Ischemic Stroke Model. J Magn Reson Imaging. 2020 Feb 29;: Authors: Wu S, Zhang H, Wang J, Li X, Gao X, Fang Z, Qu J, Wu Y, Ren Y, Rui W, Zhang J, Yao Z Abstract BACKGROUND: Despite the growing concern about the safety of gadolinium-based contrast agents (GBCAs), they are still the most commonly used. Ferumoxytol, as an off-label alternative MRI contrast agent, cannot be administered by a rapid...
Related ArticlesAssessing patient-reported symptom burden of long-term head and neck cancer survivors at annual surveillance in survivorship clinic. Head Neck. 2020 Feb 29;: Authors: Townes TG, Navuluri S, Pytynia KB, Gunn GB, Kamal MJ, Gilmore KR, Chapman PH, Bell KV, Fournier DM, Janik MA, Joseph LM, Zendehdel S, Hutcheson KA, Goepfert RP Abstract BACKGROUND: This study reports long-term head and neck cancer (HNC) patient-reported symptoms using...
Related ArticlesLong-term swallowing, trismus, and speech outcomes after combined chemoradiotherapy and preventive rehabilitation for head and neck cancer; 10-year plus update. Head Neck. 2020 Feb 29;: Authors: Karsten RT, van der Molen L, Hamming-Vrieze O, van Son RJJH, Hilgers FJM, van den Brekel MWM, Stuiver MM, Smeele LE Abstract BACKGROUND: The objective of this study was to explore the 10-year plus outcomes of Intensity Modulated Radiotherapy...
Related ArticlesThe Prognostic Role of Programmed Death-Ligand 1 in Nasopharyngeal Carcinoma. Laryngoscope. 2020 Feb 29;: Authors: Wotman M, Herman SW, Costantino P, Tham T Abstract OBJECTIVES: Programmed death-ligand 1 (PD-L1) is an immune checkpoint protein that may be a useful prognostic biomarker in nasopharyngeal cancer (NPC). The purpose of this systematic review and meta-analysis was to investigate the relationship between PD-L1 expression...
Related ArticlesUpdate on Pheochromocytoma and Paraganglioma from the SSO Endocrine and Head and Neck Disease Site Working Group, Part 2 of 2: Perioperative Management and Outcomes of Pheochromocytoma and Paraganglioma. Ann Surg Oncol. 2020 Feb 28;: Authors: Patel D, Phay JE, Yen TWF, Dickson PV, Wang TS, Garcia R, Yang AD, Kim LT, Solórzano CC Abstract This is the second part of a two-part review on pheochromocytoma and paragangliomas (PPGLs). In...
Related ArticlesUpdate on Pheochromocytoma and Paraganglioma from the SSO Endocrine/Head and Neck Disease-Site Work Group. Part 1 of 2: Advances in Pathogenesis and Diagnosis of Pheochromocytoma and Paraganglioma. Ann Surg Oncol. 2020 Feb 28;: Authors: Patel D, Phay JE, Yen TWF, Dickson PV, Wang TS, Garcia R, Yang AD, Solórzano CC, Kim LT Abstract This first part of a two-part review of pheochromocytoma and paragangliomas (PPGLs) addresses clinical...
Related ArticlesLaryngotracheal reconstruction in the pediatric burn patient: surgical techniques and decision-making. J Burn Care Res. 2020 Feb 29;: Authors: Jayawardena ADL, Bouhabel S, Sheridan RL, Hartnick CJ Abstract The management of laryngotracheal stenosis (LTS) in the pediatric burn patient is complex and requires a multi-disciplinary approach. The mainstay of treatment for LTS is laryngotracheal reconstruction (LTR), however, limited reports...
Related ArticlesNdrg1 Deficiency is associated with Regional Metastasis in Oral Cancer by inducing Epithelial-Mesenchymal transition. Carcinogenesis. 2020 Feb 29;: Authors: de Lima JM, Morand GB, Macedo CCS, Diesel L, Hier MP, Mlynarek A, Kowalski LP, Maschietto M, Alaoui-Jamali MA, Silva SDD Abstract Regional metastasis is the single most important prognostic factor in oral squamous cell carcinoma (OSCC). Abnormal expression of N-myc downstream-regulated...
Related ArticlesEpidemiology of Anosmia in South Korea: A Nationwide Population-Based Study. Sci Rep. 2020 Feb 28;10(1):3717 Authors: Kang JW, Lee YC, Han K, Kim SW, Lee KH Abstract Research about the epidemiology of olfactory dysfunction in Asians was not enough. The purpose of this study was to assess the prevalence and incidence rate of olfactory disorders in Koreans and to evaluate demographic risk factors. We analyzed clinical data of patients...
Related ArticlesTreatment outcomes in acute invasive fungal rhinosinusitis extending to the extrasinonasal area. Sci Rep. 2020 Feb 28;10(1):3688 Authors: Nam SH, Chung YS, Choi YJ, Lee JH, Kim JH Abstract Acute invasive fungal rhinosinusitis (AIFRS) can spread beyond the sinonasal cavity. It is necessary to analyze the association between the specific site involved in the extrasinonasal area and the survival rate to predict patient prognosis. We...
Related ArticlesCharacterization of the Airflow within an Average Geometry of the Healthy Human Nasal Cavity. Sci Rep. 2020 Feb 28;10(1):3755 Authors: Brüning J, Hildebrandt T, Heppt W, Schmidt N, Lamecker H, Szengel A, Amiridze N, Ramm H, Bindernagel M, Zachow S, Goubergrits L Abstract This study's objective was the generation of a standardized geometry of the healthy nasal cavity. An average geometry of the healthy nasal cavity was generated using...
Related ArticlesXerostomia and Clinical Outcomes in Definitive Intensity Modulated Radiotherapy (IMRT) Versus Three-dimensional Conformal Radiotherapy (3D-CRT) for Head and Neck Squamous Cell Carcinoma: A Meta-analysis. In Vivo. 2020 Mar-Apr;34(2):623-629 Authors: DE Felice F, Pranno N, Papi P, Brugnoletti O, Tombolini V, Polimeni A Abstract BACKGROUND/AIM: Intensity modulated radiotherapy (IMRT) has been compared with three-dimensional conformal...
Related ArticlesEffects of Cinnamaldehyde on the Viability and Expression of Chemokine Receptor Genes in Temozolomide-treated Glioma Cells. In Vivo. 2020 Mar-Apr;34(2):595-599 Authors: Chen JC, Hsieh PS, Chen SM, Hwang JH Abstract BACKGROUND/AIM: The effects of cinnamaldehyde on glioma are still unclear. We aimed to investigate the effects of cinnamaldehyde on the viability and expression of chemokine receptors CXCR4 and CXCR7 in temozolomide (TMZ)-treated...
Related ArticlesSolitary neurofibroma of maxilla: a rare clinical entity. BMJ Case Rep. 2020 Feb 28;13(2): Authors: Grewal M, Saini N, Gautam S, Garg P Abstract Neurofibroma (NF) is a benign tumour of the peripheral nervous system which is rare in head and neck region. Head and neck NF are mostly located in the soft tissue and rarely seen intraosseously. These may present either as solitary lesions or as part of the generalised syndrome of neurofibromatosis...
Related ArticlesPlasma DNA end motif profiling as a fragmentomic marker in cancer, pregnancy and transplantation. Cancer Discov. 2020 Feb 28;: Authors: Jiang P, Sun K, Peng W, Cheng SH, Ni M, Yeung PC, Heung MMS, Xie T, Shang H, Zhou Z, Chan RWY, Wong J, Wong VWS, Poon LC, Leung TY, Lam WKJ, Chan JYK, Chan HLY, Chan KCA, Chiu RWK, Lo YMD Abstract Plasma DNA fragmentomics is an emerging area of research covering plasma DNA sizes, end-points, and nucleosome...
Related ArticlesAberrant DNA hypermethylation-silenced LINC00886 gene accelerates malignant progression of laryngeal carcinoma. Pathol Res Pract. 2020 Feb 13;:152877 Authors: Lan L, Cao H, Chi W, Meng W, Zhao L, Cui W, Wang B Abstract BACKGROUND: Long noncoding RNAs (lncRNAs) play crucial role in formation and progression of tumors. DNA methylation has become increasingly recognized as a frequent event of epigenetic alterations and one of the primary...
Related ArticlesBilateral vocal fold immobility: Clinical findings of ten cases and suggested treatment options. Auris Nasus Larynx. 2020 Feb 26;: Authors: Matsushima K, Hajime H, Oridate N Abstract OBJECTIVE: To present the clinical findings of 10 cases of bilateral vocal fold immobility (adducted type) and suggest potential treatment options. METHODS: This retrospective study included 10 patients who underwent tracheostomy for restricted...
Related ArticlesIgG4-related disease presenting as otogenic skull base osteomyelitis. Auris Nasus Larynx. 2020 Feb 25;: Authors: Yim CD, An HJ, Ahn SK, Hur DG, Lee HJ Abstract IgG4-related disease (IgG4-RD) is an emerging clinical disease entity characterized by tumefactive lesions at multiple sites with a dense lymphoplasmacytic infiltrate rich in IgG4+ plasma cells. Although almost any organ can be affected, IgG4-RD is most likely to involve the...
Related ArticlesAn Innovative Treatment Approach Using Digital Workflow and CAD-CAM Part 2: The Restoration of Molar Incisor Hypomineralization in Children. Int J Environ Res Public Health. 2020 Feb 26;17(5): Authors: Davidovich E, Dagon S, Tamari I, Etinger M, Mijiritsky E Abstract Until recently, the treatment for molar incisor hypomineralization (MIH) mainly included interim restorations such as resin restorations and stainless-steel crowns. These...
Related ArticlesDose Reduction to the Swallowing Apparatus and the Salivary Glands by De-Intensification of Postoperative Radiotherapy in Patients with Head and Neck Cancer: First (Treatment Planning) Results of the Prospective Multicenter DIREKHT Trial. Cancers (Basel). 2020 Feb 26;12(3): Authors: Haderlein M, Speer S, Ott O, Lettmaier S, Hecht M, Semrau S, Frey B, Scherl C, Iro H, Kesting M, Fietkau R Abstract AIM: Evaluating radiotherapy treatment...
Related ArticlesTo Eat or Not to Eat: A Review of the Relationship between Chocolate and Migraines. Nutrients. 2020 Feb 26;12(3): Authors: Nowaczewska M, Wiciński M, Kaźmierczak W, Kaźmierczak H Abstract Migraine is a chronic disorder with episodic attacks, and patients with a migraine often report that certain factors can trigger their headache, with chocolate being the most popular type of food-based trigger. Many studies have suggested a link...
Related ArticlesElectrode Afterload: A Valuable Technique in a Case of Short Electrode Insertion. Case Rep Otolaryngol. 2020;2020:3910138 Authors: Riemann C, Scholz S, Sudhoff H, Todt I Abstract Introduction. The location of the electrode inside the cochlea is important for speech performance. However, many variables, including array length, insertion depth, and individual anatomy, may affect the intracochlear position of the electrode. Insertion deeper...
Related ArticlesIbrutinib-Induced Vasculitis in a Patient with Metastatic Colon Cancer Treated in Combination with Cetuximab. Case Rep Oncol Med. 2020;2020:6154213 Authors: Chi J, Park J, Saif MW Abstract Combination therapy with ibrutinib and cetuximab is being studied in a phase 1b/2 trial in patients with advanced gastrointestinal and genitourinary malignancies. Rash is a common cutaneous adverse effect for both medications. Ibrutinib is a Bruton's...
Related ArticlesModified Lothrop (Draf III) procedure for the treatment of a recurrent orbitofrontal cholesterol granuloma: A case report. SAGE Open Med Case Rep. 2020;8:2050313X20907809 Authors: Yokoi H, Yamanaka H, Matsumoto Y, Kawada M, Fujiwara M, Ohara A, Saito K Abstract Orbitofrontal cholesterol granuloma is a rare occurrence. Here, we present a case involving a 64-year-old man with a recurrent orbitofrontal cholesterol granuloma treated by the...
Related ArticlesImprovements to the retractor and muscle flap design for minimally invasive cochlear implantation. J Otol. 2020 Mar;15(1):41-44 Authors: Liu R, Tan Z, Li J, Yan Y, Ren W, Zhang M, Yang S, Zhao H Abstract Objective: The aim of this study was to improve muscle flaps and to evaluate surgical outcomes with the use of a novel specialized retractor, which is a surgical instrument used to locate and shape a bony seat for minimally invasive cochlear...
Related ArticlesVertigo as the sole complaint of tympanomastoid paraganglioma. J Otol. 2020 Mar;15(1):33-35 Authors: Li XX, Cui WN, Gao GD Abstract Background: Tympanomastoid paragangliomas are usually benign, slowly growing, painless tumors. The common presenting symptoms of this tumor are pulsatile tinnitus and conductive hearing loss. Vertigo as the cardinal or initial symptom is extremely are, especially in the early stages of the disease. ...
Related ArticlesEndoscopic Management of Pediatric Cholesteatoma. J Otol. 2020 Mar;15(1):17-26 Authors: Ryan PJ, Patel NP Abstract Pediatric cholesteatoma occurs in one of two forms: congenital cholesteatoma, developing from embryonic epidermal cell rests or acquired cholesteatoma, associated with a focal defect in the tympanic membrane. This disease has been traditionally managed with the operating microscope, often requiring mastoidectomy for adequate...
Related ArticlesGetting started in endoscopic ear surgery. J Otol. 2020 Mar;15(1):6-16 Authors: Ryan P, Wuesthoff C, Patel N Abstract Endoscopic ear surgery (EES) is an exciting, rapidly developing and innovative field of otologic surgery. Technically and conceptually, EES is a significant departure from traditional microscopic transcanal approaches to the middle ear and canal that has shown very positive results with respect to patient outcomes. This...
Related ArticlesTranscanal endoscopic assisted skull base endolymphatic sac tumor resection: A rare disease with advanced technology. J Otol. 2020 Mar;15(1):1-5 Authors: Chang WT, Tam KY, Yao H, Chow KH, Fai Tong MC Abstract Endolymphatic sac tumors (ELSTs) are rare, papillary adenomatous tumors that arise from the endothelium of the endolymphatic sac. We demonstrate a difficult case of endolymphatic sac tumor and how it is managed via transcanal endoscopic...
Related ArticlesManagement of Ewing Sarcoma Family of Tumors: A Short Description of a Rare Primitive Uterine pPNET and Literature Review. Onco Targets Ther. 2020;13:1179-1184 Authors: Pisconti S, Della Vittoria Scarpati G, Buonerba C, Messinese S, Carella R, Di Marzo M, Di Lorenzo G, Lazzari G, Perri F, Solla R Abstract Purpose: To describe the outcome of a patient with a rare primitive uterine pPNET and to perform a review of the available data in...
Related ArticlesSurgical outcomes of the endonasal endoscopic approach within a standardized management protocol for repair of spontaneous cerebrospinal fluid rhinorrhea. J Neurosurg. 2020 Feb 28;:1-7 Authors: Kreatsoulas DC, Shah VS, Otto BA, Carrau RL, Prevedello DM, Hardesty DA Abstract OBJECTIVE: Spontaneous CSF leaks are rare, their diagnosis is often delayed, and they can precipitate meningitis. Craniotomy is the historical "gold standard" repair...
Related ArticlesAssociations Between Perioperative Crystalloid Volume and Adverse Outcomes in Five Surgical Populations. J Surg Res. 2020 Feb 25;251:26-32 Authors: Chen F, Rasouli MR, Ellis AR, Ohnuma T, Bartz RR, Krishnamoorthy V, Haines KL, Raghunathan K Abstract BACKGROUND: Optimal administration of fluids is an important part of enhanced recovery after surgery (ERAS) protocols. We sought to examine the relationship between perioperative crystalloid...
Related ArticlesRenal anomalies and microtia: Determining the clinical utility of screening affected children. Int J Pediatr Otorhinolaryngol. 2020 Feb 15;133:109957 Authors: Kini S, Barton GW, Carol Liu YC Abstract OBJECTIVES: Microtia is a congenital ear anomaly that hinders quality of life. Microtia patients, both syndromic and in isolation, may be at-risk for significant renal anomalies that can go undetected at the time of birth. The goal of this...
Reconstruction of pediatric skull base defects: A retrospective analysis emphasizing the very young.
Related ArticlesReconstruction of pediatric skull base defects: A retrospective analysis emphasizing the very young. Int J Pediatr Otorhinolaryngol. 2020 Feb 19;133:109962 Authors: London NR, Rangel GG, Onwuka A, Carrau RL, Prevedello DM, Leonard JA, Walz PC Abstract INTRODUCTION: Pathology of the pediatric skull base is rare and ranges from congenital defects to malignancy and traumatic defects. Pediatric patients, particularly those ≤6 years of age,...
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