IJERPH, Vol. 17, Pages 987: Setting Priorities to Inform Assessment of Care Homes’ Readiness to Participate in Healthcare Innovation: A Systematic Mapping Review and Consensus Process International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030987 Authors: Bunn Goodman Corazzini Sharpe Handley Lynch Meyer Dening Gordon Organisational context is known to impact on the successful implementation of healthcare initiatives in...
Wed Feb 05, 2020 02:00
IJERPH, Vol. 17, Pages 990: Impact of Urbanization on PM2.5-Related Health and Economic Loss in China 338 Cities International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030990 Authors: Beidi Diao Lei Ding Qiong Zhang Junli Na Jinhua Cheng According to the requirements of the Healthy China Program, reasonable assessment of residents’ health risks and economic loss caused by urban air pollution is of great significance for environmental...
Wed Feb 05, 2020 02:00
IJERPH, Vol. 17, Pages 989: Medication Use among Pregnant Women from the 2015 Pelotas (Brazil) Birth Cohort Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030989 Authors: Bárbara Heather Lutz Vanessa Iribarrem Avena Miranda Marysabel Pinto Telis Silveira Tatiane da Silva Dal Pizzol Sotero Serrate Mengue Mariângela Freitas da Silveira Marlos Rodrigues Domingues Andréa Dâmaso Bertoldi Background: Medication use during pregnancy...
Wed Feb 05, 2020 02:00
IJERPH, Vol. 17, Pages 986: The Intercontinental Terminals Chemical Fire Study: A Rapid Response to an Industrial Disaster to Address Resident Concerns in Deer Park, Texas International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030986 Authors: Heyreoun An Han Inkyu Han Sheryl McCurdy Kristina Whitworth George Delclos Amal Rammah Elaine Symanski On Sunday, 17 March 2019, a fire erupted at the Intercontinental Terminals Company (ITC, Deer...
Wed Feb 05, 2020 02:00
IJERPH, Vol. 17, Pages 988: Association between Generalized Anxiety Disorder and Premenstrual Dysphoric Disorder in a Diagnostic Interviewing Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030988 Authors: Yen Lin Huang Chou Long Ko Background: Premenstrual dysphoric disorder (PMDD) demonstrates predictable, cyclic, affective and somatic symptoms that are aggravated in the late luteal phase and are resolved by menstruation....
Wed Feb 05, 2020 02:00
IJERPH, Vol. 17, Pages 985: Decreasing the Impact of Anxiety on Cancer Prevention through Online Intervention International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030985 Authors: Maksymilian Gajda Małgorzata Kowalska Background: Low levels of public knowledge, incorrect beliefs, and anxiety are the most often mentioned factors that may negatively affect the implementation of preventive campaigns and timely diagnosis of cancer. Cancer is a major unresolved...
Wed Feb 05, 2020 02:00
IJERPH, Vol. 17, Pages 983: Assessing the Effects of Desertification Control Projects from the Farmers’ Perspective: A Case Study of Yanchi County, Northern China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030983 Authors: Xuan Wei Lihua Zhou Guojing Yang Ya Wang Yong Chen Desertification has inflicted severe damage on the natural environment and social economy for decades, particularly in the arid and semi-arid regions of northern...
Wed Feb 05, 2020 02:00
IJERPH, Vol. 17, Pages 984: Syphilis Notifications and the Triggering Processes for Vertical Transmission: A Cross-Sectional Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030984 Authors: Samara Isabela Maia de Oliveira Cecília Olívia Paraguai de Oliveira Saraiva Débora Feitosa de França Marcos Antônio Ferreira Júnior Libna Helen de Melo Lima Nilba Lima de Souza Syphilis is a disease that is found all over the world that causes...
Wed Feb 05, 2020 02:00
IJERPH, Vol. 17, Pages 982: Occupational Factors Associated with Health-Related Quality of Life in Nursing Professionals: A Multi-Centre Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030982 Authors: María Dolores Ruiz-Fernández Ángela María Ortega-Galán Cayetano Fernández-Sola José Manuel Hernández-Padilla José Granero-Molina Juan Diego Ramos-Pichardo Background: Nursing professionals are exposed to stressful situations arising...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1066: The Clustering of mApoE Anti-Amyloidogenic Peptide on Nanoparticle Surface Does Not Alter Its Performance in Controlling Beta-Amyloid Aggregation International Journal of Molecular Sciences doi: 10.3390/ijms21031066 Authors: Corti Cox Cassina Nardo Salerno Marrano Missana Andreozzi Silva Stellacci Dal Magro Re Mantegazza The deposition of amyloid-β (Aβ) plaques in the brain is a significant...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1065: Poplar PdPTP1 Gene Negatively Regulates Salt Tolerance by Affecting Ion and ROS Homeostasis in Populus International Journal of Molecular Sciences doi: 10.3390/ijms21031065 Authors: Yingying Lu Wanlong Su Yu Bao Shu Wang Fang He Dongli Wang Xiaoqian Yu Weilun Yin Chao Liu Xinli Xia High concentrations of Na+ in saline soil impair plant growth and agricultural production. Protein tyrosine phosphorylation is crucial in many cellular...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1059: Novel ACE Inhibitory Peptides Derived from Simulated Gastrointestinal Digestion in Vitro of Sesame (Sesamum indicum L.) Protein and Molecular Docking Study International Journal of Molecular Sciences doi: 10.3390/ijms21031059 Authors: Wang Lu Sun Gao Ma Huang The aim of this study was to isolate and identify angiotensin I-converting enzyme (ACE) inhibitory peptides from sesame protein through simulated gastrointestinal digestion in vitro,...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1060: Is There a Role for Dual PI3K/mTOR Inhibitors for Patients Affected with Lymphoma? International Journal of Molecular Sciences doi: 10.3390/ijms21031060 Authors: Tarantelli Lupia Stathis Bertoni The activation of the PI3K/AKT/mTOR pathway is a main driver of cell growth, proliferation, survival, and chemoresistance of cancer cells, and, for this reason, represents an attractive target for developing targeted anti-cancer drugs. There are plenty...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1061: Defeating Antibiotic-Resistant Bacteria: Exploring Alternative Therapies for a Post-Antibiotic Era International Journal of Molecular Sciences doi: 10.3390/ijms21031061 Authors: Wang Hsieh Powers Kao Antibiotics are one of the greatest medical advances of the 20th century, however, they are quickly becoming useless due to antibiotic resistance that has been augmented by poor antibiotic stewardship and a void in novel antibiotic discovery. Few novel...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1062: A Role of Microtubules in Oligodendrocyte Differentiation International Journal of Molecular Sciences doi: 10.3390/ijms21031062 Authors: Lee Hur Oligodendrocytes are specialized cells that myelinate axons in the central nervous system. Defects in oligodendrocyte function and failure to form or maintain myelin sheaths can cause a number of neurological disorders. Oligodendrocytes are differentiated from oligodendrocyte progenitor cells (OPCs), which extend...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1064: Rabs in Signaling and Embryonic Development International Journal of Molecular Sciences doi: 10.3390/ijms21031064 Authors: Sonya Nassari Tomas Del Olmo Steve Jean Rab GTPases play key roles in various cellular processes. They are essential, among other roles, to membrane trafficking and intracellular signaling events. Both trafficking and signaling events are crucial for proper embryonic development. Indeed, embryogenesis is a complex process in which...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1058: Targeting Insulin-Like Growth Factor 1 Receptor Delays M-Phase Progression and Synergizes with Aurora B Inhibition to Suppress Cell Proliferation International Journal of Molecular Sciences doi: 10.3390/ijms21031058 Authors: Akane Yamagishi Yuki Ikeda Masayoshi Ikeuchi Ryuzaburo Yuki Youhei Saito Yuji Nakayama The insulin-like growth factor 1 receptor (IGF1R) is a receptor-type tyrosine kinase that transduces signals related to cell proliferation,...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1063: Ganglioside Synthesis by Plasma Membrane-Associated Sialyltransferase in Macrophages International Journal of Molecular Sciences doi: 10.3390/ijms21031063 Authors: Aldo A. Vilcaes Eduardo Garbarino-Pico Vanina Torres Demichelis Jose L. Daniotti Gangliosides are constituents of the mammalian cell membranes and participate in the inflammatory response. However, little is known about the presence and enzymatic activity of ganglioside sialyltransferases...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1055: Mutual Two-Way Interactions of Curcumin and Gut Microbiota International Journal of Molecular Sciences doi: 10.3390/ijms21031055 Authors: Ryszard Pluta Sławomir Januszewski Marzena Ułamek-Kozioł Curcumin, an herbal naturally occurring polyphenol, has recently been proposed for the treatment of neurodegenerative, neurological and cancer diseases due to its pleiotropic effect. Recent studies indicated that dysbiosis is associated with the abovementioned...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1056: Regulation of Osteoclast Differentiation at Multiple Stages by Protein Kinase D Family Kinases International Journal of Molecular Sciences doi: 10.3390/ijms21031056 Authors: Leightner Mello Guimaraes Meyers Evans Mansky Gopalakrishnan Jensen Balanced osteoclast and osteoblast activity is necessary for skeletal health, whereas unbalanced osteoclast activity causes bone loss in many skeletal conditions. A better understanding of pathways...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1057: Maintenance of the Undifferentiated State in Myogenic Progenitor Cells by TGFβ Signaling is Smad Independent and Requires MEK Activation International Journal of Molecular Sciences doi: 10.3390/ijms21031057 Authors: Tetsuaki Miyake Arif Aziz John C. McDermott Transforming growth factor β (TGFβ) is a pluripotent cytokine and regulates a myriad of biological processes. It has been established that TGFβ potently inhibits skeletal...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1053: Gene Prioritization through Consensus Strategy, Enrichment Methodologies Analysis, and Networking for Osteosarcoma Pathogenesis International Journal of Molecular Sciences doi: 10.3390/ijms21031053 Authors: Alejandro Cabrera-Andrade Andrés López-Cortés Gabriela Jaramillo-Koupermann César Paz-y-Miño Yunierkis Pérez-Castillo Cristian R. Munteanu Humbert González-Díaz Alejandro Pazos Eduardo Tejera Osteosarcoma is the most common subtype...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1052: Metal-Free Carbon Quantum Dots Implant Graphitic Carbon Nitride: Enhanced Photocatalytic Dye Wastewater Purification with Simultaneous Hydrogen Production International Journal of Molecular Sciences doi: 10.3390/ijms21031052 Authors: Lilei Zhang Jingxiao Zhang Yuanyu Xia Menghan Xun Hong Chen Xianghui Liu Xia Yin The use of photocatalysts to purify wastewater and simultaneously convert solar energy into clean hydrogen energy is of considerable...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1051: Leptin, Adiponectin, and Sam68 in Bone Metastasis from Breast Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21031051 Authors: Paola Maroni The most serious aspect of neoplastic disease is the spread of cancer cells to secondary sites. Skeletal metastases can escape detection long after treatment of the primary tumour and follow-up. Bone tissue is a breeding ground for many types of cancer cells, especially those derived from the breast,...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1050: Dexamethasone Treatment Increases the Intracellular Calcium Level Through TRPV6 in A549 Cells International Journal of Molecular Sciences doi: 10.3390/ijms21031050 Authors: Bo-Hui Jeon Yeong-Min Yoo Eui-Man Jung Eui-Bae Jeung This study investigated the effect of dexamethasone (DEX) on intracellular calcium levels and the expressions of transient receptor potential cation channel subcomponent V member 6 (TRPV6), sodium-calcium exchanger 1 (NCX1), and...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1049: A Simplified Method for Simultaneous Determination of α-Lipoic Acid and Low-Molecular-Mass Thiols in Human Plasma International Journal of Molecular Sciences doi: 10.3390/ijms21031049 Authors: Kamila Borowczyk Patrycja Olejarz Grażyna Chwatko Marcin Szylberg Rafał Głowacki α-Lipoic acid, glutathione, cysteine, and cysteinylglycine can be applied as therapeutic agents in civilization diseases such as diabetes mellitus, cardiovascular diseases,...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1048: The Intravitreal Injection of Lanosterol Nanoparticles Rescues Lens Structure Collapse at an Early Stage in Shumiya Cataract Rats International Journal of Molecular Sciences doi: 10.3390/ijms21031048 Authors: Noriaki Nagai Yuya Fukuoka Kanta Sato Hiroko Otake Atsushi Taga Mikako Oka Noriko Hiramatsu Naoki Yamamoto We designed an intravitreal injection formulation containing lanosterol nanoparticles (LAN-NPs) via the bead mill method and...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1046: TGF–β3 Loaded Electrospun Polycaprolacton Fibre Scaffolds for Rotator Cuff Tear Repair: An in Vivo Study in Rats International Journal of Molecular Sciences doi: 10.3390/ijms21031046 Authors: Janin Reifenrath Mathias Wellmann Merle Kempfert Nina Angrisani Bastian Welke Sarah Gniesmer Andreas Kampmann Henning Menzel Elmar Willbold Biological factors such as TGF–β3 are possible supporters of the healing process in chronic...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1045: Candidate SNP Markers of Atherogenesis Significantly Shifting the Affinity of TATA-Binding Protein for Human Gene Promoters show stabilizing Natural Selection as a Sum of Neutral Drift Accelerating Atherogenesis and Directional Natural Selection Slowing It International Journal of Molecular Sciences doi: 10.3390/ijms21031045 Authors: Ponomarenko Rasskazov Chadaeva Sharypova Drachkova Oshchepkov Ponomarenko Savinkova Oshchepkova ...
Wed Feb 05, 2020 02:00
IJMS, Vol. 21, Pages 1047: A Pilot Study on the Effects of l-Carnitine and Trimethylamine-N-Oxide on Platelet Mitochondrial DNA Methylation and CVD Biomarkers in Aged Women International Journal of Molecular Sciences doi: 10.3390/ijms21031047 Authors: Laura Bordoni Angelika K. Sawicka Arkadiusz Szarmach Pawel J. Winklewski Robert A. Olek Rosita Gabbianelli l-carnitine supplementation has been used for cardiovascular health protection for a long time. Recently, trimethylamine-N-oxide...
Wed Feb 05, 2020 02:00
JCDD, Vol. 7, Pages 6: Impact of the 2019 European Guidelines on Diabetes in Clinical Practice: Real and Simulated Analyses of Lipid Goals Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7010006 Authors: Walter Masson Melina Huerín Lorenzo Martin Lobo Gerardo Masson Graciela Molinero Mariano Nemec Mariela Boccadoro Cinthia Romero Gabriel Micali Daniel Siniawski Background: Recent European guidelines on diabetes, prediabetes, and cardiovascular...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 393: Markov State Modelling of Disease Courses and Mortality Risks of Patients with Community-Acquired Pneumonia Journal of Clinical Medicine doi: 10.3390/jcm9020393 Authors: Jens Przybilla Peter Ahnert Holger Bogatsch Frank Bloos Frank M. Brunkhorst PROGRESS Study Group Bauer Loeffler Witzenrath Suttorp Scholz SepNet Critical Care Trials Group Community-acquired pneumonia (CAP) is one of the most frequent infectious diseases...
Sat Feb 01, 2020 02:00
JCM, Vol. 9, Pages 435: A Cohort Study of Antihyperglycemic Medication Exposure and Gastric Cancer Risk Journal of Clinical Medicine doi: 10.3390/jcm9020435 Authors: Dulskas Patasius Kaceniene Linkeviciute-Ulinskiene Zabuliene Smailyte We assessed gastric cancer risk in type 2 diabetes mellitus patients. Gastric cancer patients with diabetes between 2001–2012 were identified. Four groups were analysed: combination therapy with metformin users; insulin and...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 428: Chronic Oral Palmitoylethanolamide Administration Rescues Cognitive Deficit and Reduces Neuroinflammation, Oxidative Stress, and Glutamate Levels in A Transgenic Murine Model of Alzheimer’s Disease Journal of Clinical Medicine doi: 10.3390/jcm9020428 Authors: Beggiato Tomasini Cassano Ferraro N-palmitoylethanolamide (PEA) is a lipid mediator belonging to the class of the N-acylethanolamine. Products containing PEA, also in ultramicronized formulation...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 430: Curcumin’s Nanomedicine Formulations for Therapeutic Application in Neurological Diseases Journal of Clinical Medicine doi: 10.3390/jcm9020430 Authors: Salehi Calina Docea Koirala Aryal Lombardo Pasqua Taheri Marina Salgado Castillo Martorell Martins Iriti Suleria Sharifi-Rad The brain is the body’s control center, so when a disease affects it, the outcomes are devastating. Alzheimer’s and...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 433: Muscle Activity of the Latissimus Dorsi after Tendon Transfer in Patients with Rotator Cuff Tears Journal of Clinical Medicine doi: 10.3390/jcm9020433 Authors: Hetto Spranz Zeifang Wolf van Drongelen Maier Sowa Background: Massive irreparable posterosuperior rotator cuff tears may result in the loss of external rotation. Most of the patients with posterosuperior rotator cuff tears suffer from a restriction in their daily life actions....
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 431: Cardiovascular and Autonomic Responses to Energy Drinks—Clinical Implications Journal of Clinical Medicine doi: 10.3390/jcm9020431 Authors: Somers Svatikova There is an increasing consumption of energy drinks both in the United States and worldwide. The components of these beverages are sometimes unclear but commonly include caffeine, sugars, taurine, and B-vitamins. Young people, particularly those engaged in sports, studying, and in the military are especially...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 432: The Right Ventricle—You May Forget it, but It Will Not Forget You Journal of Clinical Medicine doi: 10.3390/jcm9020432 Authors: Wanner Filipovic Right ventricular (RV) dysfunction and failure are common and often overlooked causes of perioperative deterioration and adverse outcomes. Due to its unique pathophysiologic underpinnings, RV failure often does not respond to typical therapeutic measures such as volume resuscitation and often worsens when therapy...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 429: Anesthetic Agents and Cardiovascular Outcomes of Noncardiac Surgery after Coronary Stent Insertion Journal of Clinical Medicine doi: 10.3390/jcm9020429 Authors: Yoon Jun Park Ji Jang Yoo Kim Kim Patients undergoing noncardiac surgery after coronary stent implantation are at an increased risk of thrombotic complications. Volatile anesthetics are reported to have organ-protective effects against ischemic injury. Propofol has an anti-inflammatory...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 427: Prognosis-Predicting Model Based on [18F]fluorodeoxyglucose PET Metabolic Parameters in Locally Advanced Cervical Cancer Patients Treated with Concurrent Chemoradiotherapy: Multi-Center Retrospective Study Journal of Clinical Medicine doi: 10.3390/jcm9020427 Authors: Won Kee Lee Gun Oh Chong Shin Young Jeong Hyun Jung Lee Shin-Hyung Park Jung Min Ryu Youn Seok Choi Sungmin Kang Yu-Jin Koo Dae Hyung Lee Eunjung Kong Sang-Woo Lee This...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 434: Pulp–Dentin Tissue Healing Response: A Discussion of Current Biomedical Approaches Journal of Clinical Medicine doi: 10.3390/jcm9020434 Authors: Shah Lynd Ho Chen Vines Jung Kim Zhang Wu Jun Cheon Dental pulp tissue exposed to mechanical trauma or cariogenic process results in root canal and/or periapical infections, and conventionally treated with root canal procedures. The more recent regenerative endodontic procedure...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 426: Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related Osteonecrosis of the Jaws in a Central European Population Journal of Clinical Medicine doi: 10.3390/jcm9020426 Authors: Tamás Vereb Krisztina Boda László Czakó Mihály Vaszilkó Gábor Fülöp Gusztáv Klenk Ágnes Janovszky Ferenc Oberna József Piffkó László Seres Objective: Bisphosphonate-related osteonecrosis of the jaws is considered to be a rare...
Wed Feb 05, 2020 02:00
JCM, Vol. 9, Pages 425: Is the Arginase Pathway a Novel Therapeutic Avenue for Diabetic Retinopathy?
JCM, Vol. 9, Pages 425: Is the Arginase Pathway a Novel Therapeutic Avenue for Diabetic Retinopathy? Journal of Clinical Medicine doi: 10.3390/jcm9020425 Authors: Esraa Shosha Abdelrahman Y. Fouda S. Priya Narayanan R. William Caldwell Ruth B. Caldwell Diabetic retinopathy (DR) is the leading cause of blindness in working age Americans. Clinicians diagnose DR based on its characteristic vascular pathology, which is evident upon clinical exam. However, extensive research has...
Wed Feb 05, 2020 02:00
JFMK, Vol. 5, Pages 11: Floating subscapularis tear: a variation of the partial subscapularis Tear Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5010011 Authors: Yamakado A variation of subscapularis tear has been identified, named floating subscapularis, where the tendon is completely detached from the lesser tuberosity but is continuous with the tissue covering the bicipital groove. An accurate diagnosis can be made using arthroscopic observation with passive external...
Wed Feb 05, 2020 02:00
JPM, Vol. 10, Pages 8: Harnessing the Potential of Stem Cells for Disease Modeling: Progress and Promises Journal of Personalized Medicine doi: 10.3390/jpm10010008 Authors: Chiara Argentati Ilaria Tortorella Martina Bazzucchi Francesco Morena Sabata Martino Ex vivo cell/tissue-based models are an essential step in the workflow of pathophysiology studies, assay development, disease modeling, drug discovery, and development of personalized therapeutic strategies. For these...
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Medicina, Vol. 56, Pages 64: A Rare Case of Fatal Endobronchial Mucormycosis Masquerading as Endobronchial Tuberculosis Medicina doi: 10.3390/medicina56020064 Authors: Minjeong Kim Jun Hyeok Lim Mihwa Park Hyung Keun Cha Lucia Kim Hae-Seong Nam Pulmonary mucormycosis is a relatively rare but often fatal opportunistic fungal infection that occurs mostly in immunocompromised patients. Endobronchial mucormycosis, a distinct clinical form of pulmonary mucormycosis, is very...
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Medicina, Vol. 56, Pages 63: A Meta-Analysis Comparing the Efficacy and Safety of Peramivir with Other Neuraminidase Inhibitors for Influenza Treatment Medicina doi: 10.3390/medicina56020063 Authors: Chen Wei Lai Weng Wang Background and Objectives: This meta-analysis compared the efficacy and safety of peramivir compared to other neuraminidase inhibitors (NAIs). Materials and Methods: Data from PubMed, Embase, and Cochrane databases and ClinicalTrials.gov were searched...
Wed Feb 05, 2020 02:00
Medicina, Vol. 56, Pages 62: Rare Breast Carcinoma with Paradoxical Plasma Cell Immunoprofile: A Case Report Medicina doi: 10.3390/medicina56020062 Authors: Grădinaru Stoicea Mocanu Antoniac Gheorghiță Grigore Plasma cell features are encountered in a variety of non-plasma cell neoplasias, especially carcinomas of a discohesive type, such as those occurring in the digestive tract and breast. Lobular carcinomas of the breast present themselves in a variety of architectural...
Wed Feb 05, 2020 02:00
Medicines, Vol. 7, Pages 8: Knowledge, Attitude, and Practice of Yoga in Rural and Urban India, KAPY 2017: A Nationwide Cluster Sample Survey Medicines doi: 10.3390/medicines7020008 Authors: Mishra SK HS Nagarathna Anand Bhutani Sivapuram Singh Nagendra : Background: To examine the knowledge, attitudes, and practice gap of yoga across India based on implicit perceptions. Methods: The present study is a nationwide door-to-door survey conducted using a...
Wed Feb 05, 2020 02:00
Microorganisms, Vol. 8, Pages 214: Succession and Colonization Dynamics of Endolithic Phototrophs within Intertidal Carbonates Microorganisms doi: 10.3390/microorganisms8020214 Authors: Roush Garcia-Pichel Photosynthetic endolithic communities are common in shallow marine carbonates, contributing significantly to their bioerosion. Cyanobacteria are well known from these settings, where a few are euendoliths, actively boring into the virgin substrate. Recently, anoxygenic phototrophs...
Wed Feb 05, 2020 02:00
Microorganisms, Vol. 8, Pages 213: Rhizosphere Microbiome of Arid Land Medicinal Plants and Extra Cellular Enzymes Contribute to Their Abundance Microorganisms doi: 10.3390/microorganisms8020213 Authors: Khan Asaf Abed Ning Chai Al-Rawahi Mohanta Al-Rawahi Schachtman Al-Harrasi Revealing the unexplored rhizosphere microbiome of plants in arid environments can help in understanding their interactions between microbial communities and plants during harsh...
Wed Feb 05, 2020 02:00
Microorganisms, Vol. 8, Pages 212: Proposing BCG Vaccination for Mycobacterium avium ss. paratuberculosis (MAP) Associated Autoimmune Diseases Microorganisms doi: 10.3390/microorganisms8020212 Authors: Dow Bacille Calmette–Guerin (BCG) vaccination is widely practiced around the world to protect against the mycobacterial infection tuberculosis. BCG is also effective against the pathogenic mycobacteria that cause leprosy and Buruli’s ulcer. BCG is part of the standard...
Wed Feb 05, 2020 02:00
Microorganisms, Vol. 8, Pages 211: The Dysbiosis of Gut Microbiota Caused by Low-Dose Cadmium Aggravate the Injury of Mice Liver through Increasing Intestinal Permeability Microorganisms doi: 10.3390/microorganisms8020211 Authors: Liu Li Xia Liu Ren Ji Cadmium (Cd), widely present in food and drinking water at low doses, can cause health risks. However, the mechanistic effects of long-term Cd exposure at low dose through dietary intake is poorly studied. The aim...
Wed Feb 05, 2020 02:00
Molbank, Vol. 2020, Article M1116: 4-(2-Bromovinyl)benzocyclobutene Molbank doi: 10.3390/M1116 Authors: Chudov Levchenko Shmelin Grebennikov 4-(2-Bromovinyl)benzocyclobutene was prepared via a five stage synthesis starting from benzocyclobutene in an overall 30% yield. 4-(2-Bromovinyl)benzocyclobutene has a potential applications in synthesis of monomers for dielectric materials.
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 682: Modulation of Allicin-Free Garlic on Gut Microbiome Molecules doi: 10.3390/molecules25030682 Authors: Keyu Chen Yasushi Nakasone Kun Xie Kozue Sakao De-Xing Hou The allicin diallyldisulfid-S-oxide, a major garlic organosulfur compound (OSC) in crushed garlic (Allium sativum L.), possesses antibacterial effects, and influences gut bacteria. In this study, we made allicin-free garlic (AFG) extract and investigated its effects on gut microbiome....
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 681: Tricyclic Nucleobase Analogs and Their Ribosides as Substrates and Inhibitors of Purine-Nucleoside Phosphorylases III. Aminopurine Derivatives Molecules doi: 10.3390/molecules25030681 Authors: Stachelska-Wierzchowska Wierzchowski Górka Bzowska Stolarski Wielgus-Kutrowska Etheno-derivatives of 2-aminopurine, 2-aminopurine riboside, and 7-deazaadenosine (tubercidine) were prepared and purified using standard methods. 2-Aminopurine reacted...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 680: Predicting Future Prospects of Aptamers in Field-Effect Transistor Biosensors Molecules doi: 10.3390/molecules25030680 Authors: Cao-An Vu Wen-Yih Chen Aptamers, in sensing technology, are famous for their role as receptors in versatile applications due to their high specificity and selectivity to a wide range of targets including proteins, small molecules, oligonucleotides, metal ions, viruses, and cells. The outburst of field-effect transistors provides...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 679: Insoluble-Bound Polyphenols Released from Guarana Powder: Inhibition of Alpha-Glucosidase and Proanthocyanidin Profile Molecules doi: 10.3390/molecules25030679 Authors: Pinaffi Sampaio Soares Shahidi de Camargo Torres The Brazilian Food Supplement Law recently recognized that guarana (Paullinia cupana) contains bioactive substances, hence supporting its role as a functional food ingredient. The health benefits of guarana are associated,...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 677: Synthesis and In Vitro Photocytotoxicity of 9-/13-Lipophilic Substituted Berberine Derivatives as Potential Anticancer Agents Molecules doi: 10.3390/molecules25030677 Authors: Lin Ho Tsai Yang Yang Kuo Chen Liu Wu The objective of this study was to synthesize the 9-/13-position substituted berberine derivatives and evaluate their cytotoxic and photocytotoxic effects against three human cancer cell lines. Among all the synthesized...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 676: Comprehensive Investigation of Moringa oleifera from Different Regions by Simultaneous Determination of 11 Polyphenols Using UPLC-ESI-MS/MS Molecules doi: 10.3390/molecules25030676 Authors: Yanqin Zhu Qinhong Yin Yaling Yang In this study, we develop and validate a simultaneous quantification of polyphenols method based on an ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UPLC-ESI-MS/MS) to adequately understand...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 678: Biological Activity of Essential Oils Molecules doi: 10.3390/molecules25030678 Authors: Mancianti Ebani Essential oils (EOs) have for a long time been recognized to possess several different biological activities. Several among these secondary plant metabolites exhibit marked antimicrobial effects that have made their use as an antiseptic and/or preservative in food well known, since the ancient times [...]
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 675: Role of β-Caryophyllene in the Antinociceptive and Anti-Inflammatory Effects of Tagetes lucida Cav. Essential Oil Molecules doi: 10.3390/molecules25030675 Authors: Alberto Hernandez-Leon María Eva González-Trujano Fernando Narváez-González Gimena Pérez-Ortega Fausto Rivero-Cruz María Isabel Aguilar Tagetes lucida Cav. (Asteraceae) is an ancient medicinal plant commonly used to alleviate pain. Nevertheless, scientific studies validating this...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 671: Proteasome Inhibitors: Harnessing Proteostasis to Combat Disease Molecules doi: 10.3390/molecules25030671 Authors: Sherman Li The proteasome is the central component of the main cellular protein degradation pathway. During the past four decades, the critical function of the proteasome in numerous physiological processes has been revealed, and proteasome activity has been linked to various human diseases. The proteasome prevents the accumulation of...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 674: Simultaneous Study of Anti-Ferroptosis and Antioxidant Mechanisms of Butein and (S)-Butin Molecules doi: 10.3390/molecules25030674 Authors: Liu Li Cai Ren Zhang Deng Chen To elucidate the mechanism of anti-ferroptosis and examine structural optimization in natural phenolics, cellular and chemical assays were performed with 2′-hydroxy chalcone butein and dihydroflavone (S)-butin. C11-BODIPY staining and flow cytometric...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 672: New Potent 5α- Reductase and Aromatase Inhibitors Derived from 1,2,3-Triazole Derivative Molecules doi: 10.3390/molecules25030672 Authors: El-Naggar El-All El-Naem Abdalla Rashdan This work describes the utility of pyrazole-4-carbaldehyde 1 as starting material for the synthesis of a novel potent series of 5α-reductase and aromatase inhibitors derived from 1,2,3-triazole derivative. Condensation of 1 with active methylene and...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 670: A Density-Functional Study of the Conformational Preference of Acetylcholine in the Neutral Hydrolysis Molecules doi: 10.3390/molecules25030670 Authors: Rizka N. Fadilla Febdian Rusydi Nufida D. Aisyah Vera Khoirunisa Hermawan K. Dipojono Faozan Ahmad Mudasir Mudasir Ira Puspitasari Acetylcholine, which is associated with Alzheimer’s disease, is widely known to have conformers. The preference of each conformer to undergo neutral...
Wed Feb 05, 2020 02:00
Molecules, Vol. 25, Pages 673: Recent Progress in Nitro-Promoted Direct Functionalization of Pyridones and Quinolones Molecules doi: 10.3390/molecules25030673 Authors: Hao Nishiwaki Nitro group is one of the most important functional groups in organic syntheses because its strongly electron-withdrawing ability activates the scaffold, facilitating the reaction with nucleophilic reagents or the Diels–Alder reaction. In this review, recent progress in the nitro-promoted direct...
Wed Feb 05, 2020 02:00
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