Antioxidants, Vol. 9, Pages 137: Post-Treatment with Erinacine A, a Derived Diterpenoid of H. erinaceus, Attenuates Neurotoxicity in MPTP Model of Parkinson’s Disease Antioxidants doi: 10.3390/antiox9020137 Authors: Lee Tung Teng Shen Hsieh Huang Lee Lee Chen Chen Huang Kuo Hericium erinaceus, a valuable pharmaceutical and edible mushroom, contains potent bioactive compounds such as H. erinaceus mycelium (HEM) and its derived ethanol extraction...
Tue Feb 04, 2020 02:00
Antioxidants, Vol. 9, Pages 136: Protective Effects of Sulforaphane on Exercise-Induced Organ Damage via Inducing Antioxidant Defense Responses Antioxidants doi: 10.3390/antiox9020136 Authors: Ruhee Ma Suzuki Regular exercise is beneficial to maintain a healthy lifestyle, but the beneficial effects are lost in the case of acute exhaustive exercise; this causes significant inflammation, oxidative stress along with organ damage. Recently, sulforaphane (SFN), an indirect antioxidant,...
Tue Feb 04, 2020 02:00
Antioxidants, Vol. 9, Pages 135: Cannabidiol Protects Dopaminergic Neurons in Mesencephalic Cultures against the Complex I Inhibitor Rotenone Via Modulation of Heme Oxygenase Activity and Bilirubin Antioxidants doi: 10.3390/antiox9020135 Authors: Duvigneau Trovato Müllebner Miller Krewenka Krenn Zich Moldzio Phytocannabinoids protect neurons against stressful conditions, possibly via the heme oxygenase (HO) system. In cultures of primary mesencephalic neurons...
Tue Feb 04, 2020 02:00
Antioxidants, Vol. 9, Pages 134: Molecular Changes Induced by Oxidative Stress that Impair Human Sperm Motility Antioxidants doi: 10.3390/antiox9020134 Authors: Nowicka-Bauer Nixon A state of oxidative stress (OS) and the presence of reactive oxygen species (ROS) in the male reproductive tract are strongly correlated with infertility. While physiological levels of ROS are necessary for normal sperm functioning, elevated ROS production can overwhelm the cell’s limited antioxidant...
Tue Feb 04, 2020 02:00
Arts, Vol. 9, Pages 15: On a Curious Chance Resemblance: Rudolf von Laban’s Kinetography and the Geometric Abstractions of Sophie Taeuber-Arp Arts doi: 10.3390/arts9010015 Authors: Brandl This paper investigates a case of historical co-emergence between a modern system of dance notation and the rise of geometric abstraction in the applied arts during the first decades of the 20th century. It does so by bringing together the artistic careers of the choreographer Rudolf von Laban and...
Tue Feb 04, 2020 02:00
Atmosphere, Vol. 11, Pages 163: Exposure Indices of Extreme Wind-Driven Rain Events for Built Heritage Atmosphere doi: 10.3390/atmos11020163 Authors: Scott Allan Orr May Cassar Building performance and material change of cultural heritage in urban areas are negatively impacted by wind-driven rain (WDR). The frequency and intensity of WDR exposure are modified by climate change. Current approaches to exposure assessment emphasise prolonged exposure. Here, we propose indices to represent...
Tue Feb 04, 2020 02:00
Atmosphere, Vol. 11, Pages 164: A Stratospheric Intrusion-Influenced Ozone Pollution Episode Associated with an Intense Horizontal-Trough Event Atmosphere doi: 10.3390/atmos11020164 Authors: Yiping Wang Hongyue Wang Wuke Wang Ozone pollution is currently a serious issue in China. As an important source of tropospheric ozone, the stratospheric ozone has received less concern. This study uses a combination of ground-based ozone measurements, the latest ERA5 reanalysis data as well...
Tue Feb 04, 2020 02:00
Atmosphere, Vol. 11, Pages 161: Carbonaceous Aerosols in Contrasting Atmospheric Environments in Greek Cities: Evaluation of the EC-tracer Methods for Secondary Organic Carbon Estimation Atmosphere doi: 10.3390/atmos11020161 Authors: Dimitris G. Kaskaoutis Georgios Grivas Christina Theodosi Maria Tsagkaraki Despina Paraskevopoulou Iasonas Stavroulas Eleni Liakakou Antonis Gkikas Nikolaos Hatzianastassiou Cheng Wu Evangelos Gerasopoulos Nikolaos Mihalopoulos...
Tue Feb 04, 2020 02:00
Atmosphere, Vol. 11, Pages 160: Impacts of Biomass Burning Emission Inventories and Atmospheric Reanalyses on Simulated PM10 over Indochina Atmosphere doi: 10.3390/atmos11020160 Authors: Kyohei Takami Hikari Shimadera Katsushige Uranishi Akira Kondo Biomass burning (BB) is a major source of atmospheric particles over Indochina during the dry season. Moreover, Indochina has convoluted meteorological scales, and regional meteorological conditions dominate the transport patterns...
Tue Feb 04, 2020 02:00
Atmosphere, Vol. 11, Pages 162: Influence of Arctic Oscillation on Frequency of Wintertime Fog Days in Eastern China Atmosphere doi: 10.3390/atmos11020162 Authors: Liu Tang Yu Zhang The influence of Arctic Oscillation (AO) on the frequency of wintertime fog days in eastern China is studied based on the winter AO index, the wintertime fog-day data of national stations in China, and the National Centers for Environmental Prediction/National Center for Atmospheric Research...
Tue Feb 04, 2020 02:00
Behavioral Sciences, Vol. 10, Pages 50: Professional Training of Future Preschool Teachers in the Field of Artistic and Aesthetic Education by Means of Contextual Learning Technologies Behavioral Sciences doi: 10.3390/bs10020050 Authors: Krasovska Miskova Veremchuk The article deals with the development peculiarities of the subject artistic competence of future preschool teachers in the field of artistic and aesthetic education of children by means of contextual educational...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 236: Permanent Photodynamic Activation of the Cholecystokinin 2 Receptor Biomolecules doi: 10.3390/biom10020236 Authors: Tang Cui The cholecystokinin 2 receptor (CCK2R) is expressed in the central nervous system and peripheral tissues, playing an important role in higher nervous and gastrointestinal functions, pain sensation, and cancer growth. CCK2R is reversibly activated by cholecystokinin or gastrin, but whether it can be activated permanently is...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 235: Arsenic Toxicity: Molecular Targets and Therapeutic Agents Biomolecules doi: 10.3390/biom10020235 Authors: Nurchi Djordjevic Crisponi Alexander Bjørklund Aaseth : High arsenic (As) levels in food and drinking water, or under some occupational conditions, can precipitate chronic toxicity and in some cases cancer. Millions of people are exposed to unacceptable amounts of As through drinking water and food. Highly exposed individuals...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 237: Bioinformatics Analysis of Global Proteomic and Phosphoproteomic Data Sets Revealed Activation of NEK2 and AURKA in Cancers Biomolecules doi: 10.3390/biom10020237 Authors: Deb Sengupta Sambath Kumar Tumor heterogeneity attributes substantial challenges in determining the treatment regimen. Along with the conventional treatment, such as chemotherapy and radiotherapy, targeted therapy has greater impact in cancer management. Owing to the recent...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 238: Regulation of 8-Hydroxydaidzein in IRF3-Mediated Gene Expression in LPS-Stimulated Murine Macrophages Biomolecules doi: 10.3390/biom10020238 Authors: Nur Aziz Young-Gyu Kang Yong-Jin Kim Won-Seok Park Deok Jeong Jongsung Lee Donghyun Kim Jae Youl Cho Cytokines and chemokines are transcriptionally regulated by inflammatory transcription factors such as nuclear factor-κB (NF-κB), activator protein-1 (AP-1), and...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 234: Macromolecular Crowding Increases the Affinity of the PHD of ING4 for the Histone H3K4me3 Mark Biomolecules doi: 10.3390/biom10020234 Authors: Palacios Blanco The five members of the family of tumor suppressors ING contain a Plant Homeodomain (PHD) that specifically recognizes histone H3 trimethylated at lysine 4 (H3K4me3) with an affinity in the low micromolar range. Here, we use NMR to show that in the presence of 15% Ficoll 70, an inert macromolecular...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 233: Anticancer Activity of Rutin and Its Combination with Ionic Liquids on Renal Cells Biomolecules doi: 10.3390/biom10020233 Authors: Caparica Júlio Araújo Baby Fonte Costa Santos de Almeida The renal cell carcinoma (RCC) is the most common type of kidney cancer. Identifying novel and more effective therapies, while minimizing toxicity, continues to be fundamental in curtailing RCC. Rutin, a bioflavonoid widely found in nature,...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 231: A Thermolabile Phospholipase B from Talaromyces marneffei GD-0079: Biochemical Characterization and Structure Dynamics Study Biomolecules doi: 10.3390/biom10020231 Authors: Rabia Durrani Faez Iqbal Khan Shahid Ali Yonghua Wang Bo Yang Phospholipase B (EC 3.1.1.5) are a distinctive group of enzymes that catalyzes the hydrolysis of fatty acids esterified at the sn-1 and sn-2 positions forming free fatty acids and lysophospholipids. The structural...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 232: Nutritional Characterization of Sea Bass Processing By-Products Biomolecules doi: 10.3390/biom10020232 Authors: Munekata Pateiro Domínguez Zhou Barba Lorenzo The consumption of functional foods and nutraceuticals is gaining more importance in modern society. The exploration of alternative sources and the utilization of by-products coming from the food industry are gaining more importance. The present study aimed to characterize the...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 229: Molecular Analysis of Membrane Targeting by the C2 Domain of the E3 Ubiquitin Ligase Smurf1 Biomolecules doi: 10.3390/biom10020229 Authors: Jordan L. Scott Cary T. Frick Kristen A. Johnson Haining Liu Sylvia S. Yong Allyson G. Varney Olaf Wiest Robert V. Stahelin SMAD ubiquitination regulatory factor 1 (Smurf1) is a Nedd4 family E3 ubiquitin ligase that regulates cell motility, polarity and TGFβ signaling. Smurf1 contains an N-terminal...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 230: Role of Human Galectins in Inflammation and Cancers Associated with Endometriosis Biomolecules doi: 10.3390/biom10020230 Authors: Hisrich Young Sansone Bowens Green Lessey Blenda Galectins are a family of β-galactoside-binding proteins that contribute to multiple cellular functions, including immune surveillance and apoptosis. Human galectins are also important regulators of inflammation, making them a research target...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 227: β-Mannanase Production Using Coffee Industry Waste for Application in Soluble Coffee Processing Biomolecules doi: 10.3390/biom10020227 Authors: Favaro Baraldi Casciatori Farinas Soluble coffee offers the combined benefits of high added value and practicality for its consumers. The hydrolysis of coffee polysaccharides by the biochemical route, using enzymes, is an eco-friendly and sustainable way to improve the quality of this product, while...
Tue Feb 04, 2020 02:00
Biomolecules, Vol. 10, Pages 228: Chemical Composition of Essential Oils from Different Parts of Zingiber kerrii Craib and Their Antibacterial, Antioxidant, and Tyrosinase Inhibitory Activities Biomolecules doi: 10.3390/biom10020228 Authors: Aknarin Pintatum Surat Laphookhieo Emilie Logie Wim Vanden Berghe Wisanu Maneerat The essential oils of the fresh rhizomes; flowers; and leaves of Zingiber kerrii Craib were investigated using different extraction techniques; including...
Tue Feb 04, 2020 02:00
Brain Sciences, Vol. 10, Pages 83: Combining HF rTMS over the Left DLPFC with Concurrent Cognitive Activity for the Offline Modulation of Working Memory in Healthy Volunteers: A Proof-of-Concept Study Brain Sciences doi: 10.3390/brainsci10020083 Authors: Bakulin Zabirova Lagoda Poydasheva Cherkasova Pavlov Kopnin Sinitsyn Kremneva Fedorov Gnedovskaya Suponeva Piradov It has been proposed that the effectiveness of non-invasive brain stimulation...
Tue Feb 04, 2020 02:00
Brain Sciences, Vol. 10, Pages 82: No Immediate Effects of Transcranial Direct Current Stimulation at Various Intensities on Cerebral Blood Flow in People with Multiple Sclerosis Brain Sciences doi: 10.3390/brainsci10020082 Authors: Craig D. Workman Laura L. Boles Ponto John Kamholz Thorsten Rudroff Animal and transcranial magnetic stimulation motors have evoked potential studies suggesting that the currently used transcranial direct current stimulation (tDCS) intensities produce...
Tue Feb 04, 2020 02:00
Brain Sciences, Vol. 10, Pages 81: Effect of High Intensity Interval Training Compared to Continuous Training on Cognitive Performance in Young Healthy Adults: A Pilot Study Brain Sciences doi: 10.3390/brainsci10020081 Authors: Said Mekari Meghan Earle Ricardo Martins Sara Drisdelle Melanie Killen Vicky Bouffard-Levasseur Olivier Dupuy To improve cognitive function, moving the body is strongly recommended; however, evidence regarding the proper training modality is...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 357: From Bench to Bedside and Beyond: Therapeutic Scenario in Acute Myeloid Leukemia Cancers doi: 10.3390/cancers12020357 Authors: Gurnari Voso Maciejewski Visconte Acute myeloid leukemia (AML) is a heterogeneous group of clonal disorders characterized by abnormal proliferation of undifferentiated myeloid progenitors, impaired hematopoiesis, and variable response to therapy. To date, only about 30% of adult patients with AML become long-term survivors...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 351: Non-Coding RNAs as Regulators and Markers for Targeting of Breast Cancer and Cancer Stem Cells Cancers doi: 10.3390/cancers12020351 Authors: Prabhu Raza Karedath Raza Fathima Ahmed Kuttikrishnan Therachiyil Kulinski Dermime Junejo Steinhoff Uddin Breast cancer is regarded as a heterogeneous and complicated disease that remains the prime focus in the domain of public health concern. Next-generation sequencing...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 358: Viral miRNAs as Active Players and Participants in Tumorigenesis Cancers doi: 10.3390/cancers12020358 Authors: Gallo Miceli Bulati Iannolo Contino Conaldi The theory that viruses play a role in human cancers is now supported by scientific evidence. In fact, around 12% of human cancers, a leading cause of morbidity and mortality in some regions, are attributed to viral infections. However, the molecular mechanism remains complex to decipher....
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 360: Proton Magnetic Resonance Spectroscopy Characterization of Rathke’s Cleft Cysts (RCCs): Relevance to the Differential Diagnosis of Pituitary Adenomas and RCCs Cancers doi: 10.3390/cancers12020360 Authors: Omkar B. Ijare Martyn A. Sharpe David S. Baskin Kumar Pichumani Background: Rathke’s Cleft Cysts (RCCs) are rare epithelial cysts arising from remnants of the Rathke pouch in the pituitary gland. A subset of these lesions enlarge and produce...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 350: The Impact of Focused Ultrasound in Two Tumor Models: Temporal Alterations in the Natural History on Tumor Microenvironment and Immune Cell Response Cancers doi: 10.3390/cancers12020350 Authors: Cohen Chandran Lorsung Tomlinson Sundby Burks Frank Image-guided focused ultrasound (FUS) has been successfully employed as an ablative treatment for solid malignancies by exposing immune cells to tumor debris/antigens, consequently inducing...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 356: Visceral Adipose Tissue Radiodensity Is Linked to Prognosis in Hepatocellular Carcinoma Patients Treated with Selective Internal Radiation Therapy Cancers doi: 10.3390/cancers12020356 Authors: Maryam Ebadi Carlos Moctezuma-Velazquez Judith Meza-Junco Vickie E. Baracos Abha R. DunichandHoedl Sunita Ghosh Philippe Sarlieve Richard J. Owen Norman Kneteman Aldo J. Montano-Loza Hepatocellular carcinoma (HCC) constitutes the fourth leading...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 359: Effects of Germline CYP2W1*6 and CYP2B6*6 Single Nucleotide Polymorphisms on Mitotane Treatment in Adrenocortical Carcinoma: A Multicenter ENSAT Study Cancers doi: 10.3390/cancers12020359 Authors: Altieri Sbiera Herterich De Francia Della Casa Calabrese Pontecorvi Quinkler Kienitz Mannelli Canu Angelousi Chortis Kroiss Terzolo Fassnacht Ronchi Mitotane is the only approved drug for advanced...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 355: Return to Work of Breast Cancer Survivors: Perspectives and Challenges for Occupational Physicians Cancers doi: 10.3390/cancers12020355 Authors: Campagna Loscerbo Pilia Meloni Breast cancer is one of the most common diseases worldwide, mainly affecting the female gender. Considering the increase of breast cancer incidence and the decrease of mortality due to news diagnostic and therapeutic tools, the return to work issue after treatment is going...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 347: Effect of Vitamin D Supplementation on Survival of Digestive Tract Cancer Patients with Low Bioavailable 25-Hydroxyvitamin D levels: A Post Hoc Analysis of the AMATERASU Randomized Clinical Trial Cancers doi: 10.3390/cancers12020347 Authors: Urashima Okuyama Akutsu Ohdaira Kaji Suzuki Vitamin D has been shown to suppress the growth of cancer cells. Cancer cells are believed to take up bioavailable 25-hydroxyvitamin D (25[OH]D) (i.e.,...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 349: BRG1 Activates Proliferation and Transcription of Cell Cycle-Dependent Genes in Breast Cancer Cells Cancers doi: 10.3390/cancers12020349 Authors: Sobczak Pietrzak Płoszaj Robaszkiewicz Cancer malignancy is usually characterized by unlimited self-renewal. In some types of advanced tumors that are rapidly dividing, gene expression profiles depict elevations in pro-proliferative genes accompanied by coordinately elevated transcription of factors...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 353: Plasma Next Generation Sequencing and Droplet Digital-qPCR-Based Quantification of Circulating Cell-Free RNA for Noninvasive Early Detection of Cancer Cancers doi: 10.3390/cancers12020353 Authors: Metzenmacher Váraljai Hegedüs Cima Forster Schramm Scheffler Horn Klein Szarvas Reis Bielefeld Roesch Aigner Kunzmann Wiesweg Siveke Schuler Lueong Early detection of cancer holds high promise...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 348: Synergy between Non-Thermal Plasma with Radiation Therapy and Olaparib in a Panel of Breast Cancer Cell Lines Cancers doi: 10.3390/cancers12020348 Authors: Lafontaine Boisvert Glory Coulombe Wong Cancer therapy has evolved to a more targeted approach and often involves drug combinations to achieve better response rates. Non-thermal plasma (NTP), a technology rapidly expanding its application in the medical field, is a near room temperature...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 354: Reply to Comment on “Kadomoto, S. et al. Tumor-Associated Macrophages Induce Migration of Renal Cell Carcinoma Cells via Activation of the CCL20-CCR6 Axis” Cancers 2020 12, 89 Cancers doi: 10.3390/cancers12020354 Authors: Kadomoto Izumi Hiratsuka Nakano Naito Makino Iwamoto Yaegashi Shigehara Kadono Nakata Saito Nakagawa-Goto Mizokami We appreciate Zins and Abraham [1] commenting on our paper studying the...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 352: A Review of ULK1-Mediated Autophagy in Drug Resistance of Cancer Cancers doi: 10.3390/cancers12020352 Authors: Liu Yan Liao Wu Shi The difficulty of early diagnosis and the development of drug resistance are two major barriers to the successful treatment of cancer. Autophagy plays a crucial role in several cellular functions, and its dysregulation is associated with both tumorigenesis and drug resistance. Unc-51-like kinase 1 (ULK1) is a...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 344: Early Detection of Hyperprogressive Disease in Non-Small Cell Lung Cancer by Monitoring of Systemic T Cell Dynamics Cancers doi: 10.3390/cancers12020344 Authors: Arasanz Zuazo Bocanegra Gato Martínez-Aguillo Morilla Fernández Hernández López Alberdi Hernández Chocarro Teijeira Vera Kochan Escors Hyperprogressive disease (HPD) is an adverse outcome of immunotherapy consisting of an acceleration of...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 345: Inhibition of Wnt/β-Catenin Signaling in Neuroendocrine Tumors in vitro: Antitumoral Effects Cancers doi: 10.3390/cancers12020345 Authors: Jin Spoettl Maurer Nölting Auernhammer Background and aims: Inhibition of Wnt/β-catenin signaling by specific inhibitors is currently being investigated as an antitumoral strategy for various cancers. The role of Wnt/β-catenin signaling in neuroendocrine tumors still needs to be further...
Tue Feb 04, 2020 02:00
Cancers, Vol. 12, Pages 346: WNT5A-Induced Activation of the Protein Kinase C Substrate MARCKS Is Required for Melanoma Cell Invasion Cancers doi: 10.3390/cancers12020346 Authors: Purusottam Mohapatra Vikas Yadav Maren Toftdahl Tommy Andersson WNT5A is a well-known mediator of melanoma cell invasion and metastasis via its ability to activate protein kinase C (PKC), which is monitored by phosphorylation of the endogenous PKC substrate myristoylated alanine-rich c-kinase substrate...
Tue Feb 04, 2020 02:00
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