Antioxidants, Vol. 9, Pages 151: The Exacerbation of Aging and Oxidative Stress in the Epididymis of Sod1 Null Mice Antioxidants doi: 10.3390/antiox9020151 Authors: Noblanc Klaassen Robaire There is growing evidence that the quality of spermatozoa decreases with age and that children of older fathers have a higher incidence of birth defects and genetic mutations. The free radical theory of aging proposes that changes with aging are due to the accumulation of damage induced by...
Antioxidants, Vol. 9, Pages 150: In Vitro Aging of Human Skin Fibroblasts: Age-Dependent Changes in 4-Hydroxynonenal Metabolism Antioxidants doi: 10.3390/antiox9020150 Authors: Petkovic Bresgen Gilardoni Regazzoni Uchida Aldini Siems Eckl Evidence suggests that the increased production of free radicals and reactive oxygen species lead to cellular aging. One of the consequences is lipid peroxidation generating reactive aldehydic products, such as 4-hydroxynonenal...
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