Related ArticlesEffects of Sleep-Related Disorders on the Prognosis of Amyotrophic Lateral Sclerosis. Neurodegener Dis. 2020 Feb 28;:1-7 Authors: Reyhani A, Benbir Senel G, Karadeniz D Abstract BACKGROUND/OBJECTIVE: In this study, we demonstrated the effects of obstructive sleep apnea syndrome (OSAS) on the prognosis of amyotrophic lateral sclerosis (ALS). However, the effects of sleep-related disorders other than breathing problems are still waiting...
Tue Mar 03, 2020 14:26
Related ArticlesSuccessful same day discharge after immediate post-mastectomy alloplastic breast reconstruction: A single tertiary centre retrospective audit. J Plast Reconstr Aesthet Surg. 2020 Jan 22;: Authors: Oxley PJ, McNeely C, Janzen R, Mian RA, Lee AT, Murabit A, Wang P, McNeely D Abstract BACKGROUND: Immediate Post-Mastectomy Alloplastic Breast Reconstruction (IPMABR) traditionally requires a post-operative overnight stay. Recent initiatives...
Tue Mar 03, 2020 14:26
Related ArticlesHow do we improve histone deacetylase inhibitor drug discovery? Expert Opin Drug Discov. 2020 Mar 02;:1-3 Authors: Hamze A PMID: 32116055 [PubMed - as supplied by publisher]
Tue Mar 03, 2020 14:25
Related ArticlesMechanisms of action of currently used antiseizure drugs. Neuropharmacology. 2020 Jan 14;168:107966 Authors: Sills GJ, Rogawski MA Abstract Antiseizure drugs (ASDs) prevent the occurrence of seizures; there is no evidence that they have disease-modifying properties. In the more than 160 years that orally administered ASDs have been available for epilepsy therapy, most agents entering clinical practice were either discovered serendipitously...
Tue Mar 03, 2020 14:25
Related ArticlesDose-Ranging Effect of Adjunctive Oral Cannabidiol vs Placebo on Convulsive Seizure Frequency in Dravet Syndrome: A Randomized Clinical Trial. JAMA Neurol. 2020 Mar 02;: Authors: Miller I, Scheffer IE, Gunning B, Sanchez-Carpintero R, Gil-Nagel A, Perry MS, Saneto RP, Checketts D, Dunayevich E, Knappertz V, GWPCARE2 Study Group Abstract Importance: Clinical evidence supports effectiveness of cannabidiol for treatment-resistant seizures...
Tue Mar 03, 2020 14:25
Related ArticlesArtificial Intelligence in Medicine: Today and Tomorrow. Front Med (Lausanne). 2020;7:27 Authors: Briganti G, Le Moine O Abstract Artificial intelligence-powered medical technologies are rapidly evolving into applicable solutions for clinical practice. Deep learning algorithms can deal with increasing amounts of data provided by wearables, smartphones, and other mobile monitoring sensors in different areas of medicine. Currently, only...
Tue Mar 03, 2020 14:25
Related ArticlesTailor-Made Surgery Based on Functional Networks for Intractable Epilepsy. Front Neurol. 2020;11:73 Authors: Kamada K, Kapeller C, Takeuchi F, Gruenwald J, Guger C Abstract Normal and pathological networks related to seizure propagation have got attention to elucide complex seizure semiology and contribute to diagnosis and surgical monitoring in epilepsy treatment. Since focal and generalized epileptogenic syndromes abnormalities might...
Tue Mar 03, 2020 14:25
Related ArticlesPosterior Reversible Encephalopathy Syndrome: Clinical Features and Outcome. Front Neurol. 2020;11:71 Authors: Hinduja A Abstract Background: Posterior reversible encephalopathy syndrome (PRES) is an acute neurotoxic syndrome that is characterized by a spectrum neurological and radiological feature from various risk factors. Common neurological symptoms includes headache, impairment in level of consciousness, seizures, visual disturbances,...
Tue Mar 03, 2020 14:25
Related ArticlesStatus Epilepticus Manifested as Continuous Epileptic Spasms. Front Neurol. 2020;11:65 Authors: Liao J, Huang T, Srour M, Xiao Y, Chen Y, Lin S, Chen L, Hu Y, Men L, Wen J, Li B, Wen F, Xiong L Abstract Objective: The etiology and outcome of status epilepticus with continuous epileptic spasms have not been fully understood; and only rare cases have been reported in the literature. Here, we described 11 children, who manifested continuous...
Tue Mar 03, 2020 14:25
Related ArticlesA Case of Hyperekplexia That Started From Childhood: Clinical Diagnosis With Negative Genetic Investigations. Front Neurol. 2020;11:10 Authors: Antonioni A, Peschi G, Granieri E Abstract Here, we report the case of a 63-year-old woman affected by abnormal, excessive, and involuntary reactions to harmless and unexpected sensory stimuli, compatible with the diagnosis of hyperekplexia. It is a pathology that involves the glycinergic system...
Tue Mar 03, 2020 14:25
Related ArticlesNovel Surrogate Markers of CNS Inflammation in CSF in the Diagnosis of Autoimmune Encephalitis. Front Neurol. 2019;10:1390 Authors: Jiang JX, Fewings N, Dervish S, Fois AF, Duma SR, Silsby M, Bandodkar S, Ramanathan S, Bleasel A, John B, Brown DA, Lin MW Abstract Background: Autoimmune encephalitis (AE) is an important cause of refractory epilepsy, rapidly progressive cognitive decline, and unexplained movement disorders in adults. Whilst...
Tue Mar 03, 2020 14:25
Related ArticlesAre Anticholinergic Medications Associated With Increased Risk of Dementia and Behavioral and Psychological Symptoms of Dementia? A Nationwide 15-Year Follow-Up Cohort Study in Taiwan. Front Pharmacol. 2020;11:30 Authors: Liu YP, Chien WC, Chung CH, Chang HA, Kao YC, Tzeng NS Abstract Background/Objective: In previous reports, the usage of anticholinergic medications has been associated with an increased risk of dementia with prolonged...
Tue Mar 03, 2020 14:25
Related ArticlesEvaluation of zonisamide for the treatment of focal epilepsy: a review of pharmacokinetics, clinical efficacy and adverse effects. Expert Opin Drug Metab Toxicol. 2020 Mar 02;: Authors: Janković SM Abstract Introduction. Zonisamide is a benzisoxazole with 3-methanesulfonamide side chain, chemically unrelated with other anticonvulsants, and approved as mono-therapy of newly diagnosed focal epilepsy with or without secondary generalisation...
Tue Mar 03, 2020 14:25
Related ArticlesKainic acid-induced seizures in the common marmoset. Biochem Biophys Res Commun. 2020 Feb 27;: Authors: Ishikawa A, Mizuno Y, Sakai K, Maki T, Tanaka R, Oda Y, Niimi K, Takahashi E Abstract Treatment of epilepsy remains difficult because patients suffer from pharmacoresistant forms of the disease and drug side-effects. Thus, there is an urgent need to identify not only new antiepileptic drug candidates but also novel epileptic animal...
Tue Mar 03, 2020 14:25
Related ArticlesPrevalence and incidence of nodding syndrome and other forms of epilepsy in onchocerciasis-endemic areas in northern Uganda after the implementation of onchocerciasis control measures. Infect Dis Poverty. 2020 Mar 02;9(1):12 Authors: Gumisiriza N, Mubiru F, Siewe Fodjo JN, Mbonye Kayitale M, Hotterbeekx A, Idro R, Makumbi I, Lakwo T, Opar B, Kaducu J, Wamala JF, Colebunders R Abstract BACKGROUND: Around 2007, a nodding syndrome (NS) epidemic...
Tue Mar 03, 2020 14:25
Related ArticlesPopulation pharmacokinetics and dosing recommendations of levetiracetam in adult and elderly patients with epilepsy. J Pharm Sci. 2020 Feb 27;: Authors: Hernández-Mitre MP, Medellín-Garibay SE, Rodríguez-Leyva I, Rodríguez-Pinal CJ, Zarazúa S, Jung-Cook HH, Roberts JA, Romano-Moreno S, Milán-Segovia RDC Abstract The objective was to develop and externally validate a population pharmacokinetic model of levetiracetam in adult and elderly...
Tue Mar 03, 2020 14:25
Related ArticlesEpilepsy in older people. Lancet. 2020 Feb 29;395(10225):735-748 Authors: Sen A, Jette N, Husain M, Sander JW Abstract Globally, as populations age there will be challenges and opportunities to deliver optimal health care to senior citizens. Epilepsy, a condition characterised by spontaneous recurrent seizures, is common in older adults (aged >65 years) and yet has received comparatively little attention in this age group. In this...
Tue Mar 03, 2020 14:25
Related Articles[microsurgery 'burr hole' for intracranial tumors and mesial temporal lobe epilepsy]. Zh Vopr Neirokhir Im N N Burdenko. 2019;83(6):44-57 Authors: Pitskhelauri DI, Kudieva ES, Bykanov AE, Mel'nikova-Pitskhelauri TV, Pronin IN, Sanikidze AZ, Grachev NS Abstract PURPOSE: In recent years, neurosurgery has been characterized by a clear tendency towards the development of minimally invasive and less traumatic surgical approaches. To minimize...
Tue Mar 03, 2020 14:25
Related ArticlesImpact of therapeutic hypothermia on infantile spasms: an observational cohort study. Dev Med Child Neurol. 2020 01;62(1):62-68 Authors: Abu Dhais F, McNamara B, O'Mahony O, McSweeney N, Livingstone V, Murray DM, Boylan GB Abstract AIM: To establish the incidence of infantile spasms in children in the southern region of the Republic of Ireland and to compare the incidence of infantile spasms before and after the introduction of therapeutic...
Tue Mar 03, 2020 14:25
Related ArticlesRelation of in-utero exposure to antiepileptic drugs to pregnancy duration and size at birth. PLoS One. 2019;14(8):e0214180 Authors: Margulis AV, Hernandez-Diaz S, McElrath T, Rothman KJ, Plana E, Almqvist C, D'Onofrio BM, Oberg AS Abstract BACKGROUND: The associations of individual antiepileptic drugs (AEDs) with pregnancy duration and size at birth, and potential dose relations, are not well characterized. METHODS: This cohort...
Tue Mar 03, 2020 14:25
Related ArticlesRelationship between Pain and Functional Status in Patients with Amyotrophic Lateral Sclerosis: A Multicenter Cross-Sectional Study. J Palliat Med. 2018 05;21(5):588-591 Authors: Ishida N, Hongo S, Kumano A, Hatta H, Zakoji N, Hirutani M, Yamamoto Y, Aono H, Tuigi M, Suzuki R, Hanamitsu H, Wakasugi E, Takahashi M, Yamatani A Abstract BACKGROUND: Pain is a widely neglected symptom in patients with amyotrophic lateral sclerosis (ALS), even...
Tue Mar 03, 2020 14:25
Related ArticlesStatPearls Book. 2020 01 Authors: Abstract Topiramate (TPM) is a compound that belongs to the family of medications called antiepileptic drugs (AEDs). AEDs are generally used for neurologic and psychiatric purposes. The primary indication for this family of drugs is for seizure disorders; hence then name "antiepileptic drugs." In psychiatry, these are classically used as mood stabilizers, although their administrations have seen a broader application. Specifically,...
Tue Mar 03, 2020 14:25
Related ArticlesDensity functional theory study of gold(III)-dithiocarbamate complexes with characteristic anticancer potentials. J Inorg Biochem. 2020 Feb 24;206:111044 Authors: Lawal MM, Lawal IA, Klink MJ, Tolufashe GF, Ndagi U, Kumalo HM Abstract The application of gold as drug candidate dated back to 2500 BC and its relevance in medicine became more appealing following 1985 FDA approval of ingested Auranofin for the treatment of rheumatoid arthritis....
Tue Mar 03, 2020 14:23
Related ArticlesBioconjugates of Co(III) complexes with Schiff base ligands and cell penetrating peptides: Solid phase synthesis, characterization and antiproliferative activity. J Inorg Biochem. 2020 Feb 20;206:111041 Authors: Śmiłowicz D, Metzler-Nolte N Abstract In this work we synthesized a chelating Schiff base by a single condensation of salicylaldehyde with 3,4-diamino benzoic acid (1). This ligand was used further for complexation to CoCl2·6H2O...
Tue Mar 03, 2020 14:23
Related ArticlesBiotechnological approach to induce human fibroblast apoptosis using superparamagnetic iron oxide nanoparticles. J Inorg Biochem. 2020 Feb 01;206:111017 Authors: Ferraz FS, López JL, Lacerda SMSN, Procópio MS, Figueiredo AFA, Martins EMN, Guimarães PPG, Ladeira LO, Kitten GT, Dias FF, Domingues RZ, Costa GMJ Abstract Cancer-Associated Fibroblasts (CAFs) contribute to tumour progression and have received significant attention as a therapeutic...
Tue Mar 03, 2020 14:23
Related ArticlesSynthesis, chemical characterization and DNA interaction study of new diclofenac and ibuprofen zinc (II)-nicotinamide ternary complexes as cyclooxygenase inhibitor prototypes. J Inorg Biochem. 2020 Feb 20;206:111046 Authors: Dos Santos PR, Pich CT, Back D, Smiderle F, Dumas F, Moura S Abstract In the search for new drugs, strategies such as bioisosterism have been evidenced, in which the modification of molecules is already known to be...
Tue Mar 03, 2020 14:23
Publication date: Available online 2 March 2020Source: Auris Nasus LarynxAuthor(s): Dana Kim, Young Hyo Kim, Ju-Hee Kang, Chang-Shin Park
Tue Mar 03, 2020 14:23
Related ArticlesCurrarino syndrome presenting as a cerebrospinal fluid leak from the dermal sinus tract: case report. J Neurosurg Pediatr. 2020 Mar 06;:1-5 Authors: Kim RB, Robbins R, Rollins MD, Brockmeyer DL Abstract Currarino syndrome is an autosomal dominant condition with variable expressivity and penetrance that is associated with several classic features: sacral dysgenesis, presacral mass, and/or anorectal anomalies. The authors present a unique...
Tue Mar 03, 2020 14:21
Related ArticlesFactors associated with syrinx size in pediatric patients treated for Chiari malformation type I and syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium. J Neurosurg Pediatr. 2020 Mar 06;:1-11 Authors: Hale AT, Adelson PD, Albert GW, Aldana PR, Alden TD, Anderson RCE, Bauer DF, Bonfield CM, Brockmeyer DL, Chern JJ, Couture DE, Daniels DJ, Durham SR, Ellenbogen RG, Eskandari R, George TM, Grant GA, Graupman PC, Greene S, Greenfield...
Tue Mar 03, 2020 14:21
Related ArticlesEarly coagulopathy in children with isolated blunt head injury is associated with mortality and poor neurological outcomes. J Neurosurg Pediatr. 2020 Mar 06;:1-7 Authors: James V, Chong SL, Shetty SS, Ong GY Abstract OBJECTIVE: Traumatic brain injury (TBI) is the leading cause of long-term disability and death in children and adolescents globally. Long-term adverse outcomes, including physical, cognitive, and behavioral sequelae, have...
Tue Mar 03, 2020 14:21
Related ArticlesThe quality of YouTube videos on endoscopic third ventriculostomy and endoscopic third ventriculostomy with choroid plexus cauterization procedures available to families of patients with pediatric hydrocephalus. J Neurosurg Pediatr. 2020 Mar 06;:1-8 Authors: Sader N, Kulkarni AV, Eagles ME, Ahmed S, Koschnitzky JE, Riva-Cambrin J Abstract OBJECTIVE: YouTube has become an important information source for pediatric neurosurgical patients...
Tue Mar 03, 2020 14:21
Related ArticlesOccurrence of spinal extradural arachnoid cysts in a child with concomitant intracranial midline abnormalities: case report. J Neurosurg Pediatr. 2020 Mar 06;:1-6 Authors: Chen JA, Rosenthal Garber D, Cohen AR Abstract Spinal extradural arachnoid cysts (SEACs) are uncommon spinal lesions that may cause myelopathy, most frequently in the 2nd decade of life. There are multiple theories of their pathogenesis, and associated entities include...
Tue Mar 03, 2020 14:21
89 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Front Oncol"[jour] These pubmed results were generated on 2020/03/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Mar 03, 2020 14:18
Abstract Objectives This in situ study aims to evaluate the effects of chlorhexidine (CHX) mouth rinsing on biofilm formation and moreover on the disruption of existing mature dental biofilms. Methods Biofilms were formed in situ by five volunteers on bovine enamel specimens fixed to individual acrylic splints. For biofilm formation analysis, the volunteers...
Tue Mar 03, 2020 02:00
Related ArticlesPredictors of Sleep Duration and Sleep Disturbance in Children of a Culturally Diverse Region in North-Eastern Greece. Front Pediatr. 2020;8:23 Authors: Nena E, Cassimos D, Kaditis A, Kourantzi M, Trakada G, Economou NT, Nikolaidis PT, Rosemann T, Knechtle B, Steiropoulos P, Tsalkidis A Abstract Background Aim: The aim of this study was to examine the sleep characteristics of children and explore associations with various socio-demographic...
Tue Mar 03, 2020 16:12
Related ArticlesEffect of Competition, Signal-to-Noise Ratio, Race, and Sex on Southern American English Dialect Talkers' Sentence Recognition. J Am Acad Audiol. 2020 Jan 20;:0 Authors: Stuart A, Holt YF, Kerls AN, Smith MR Abstract BACKGROUND: Although numerous studies have examined regional and racial-ethnic labeling of talker identity, few have evaluated speech perception skills of listeners from the southern United States. PURPOSE:...
Tue Mar 03, 2020 18:08
Related ArticlesRelationship of Head Circumference and Age in the Prediction of the Real-Ear-to-Coupler Difference (RECD). J Am Acad Audiol. 2020 Feb 12;:0 Authors: Watts KM, Bagatto M, Clark-Lewis S, Henderson S, Scollie S, Blumsack J Abstract BACKGROUND: Pediatric hearing instrument fitting is optimally performed with individually obtained real-ear-to-coupler difference (RECD) measurements. If these measurements cannot be obtained, predicted values...
Tue Mar 03, 2020 18:08
Related ArticlesAre "Dichotic" Deficits Uniquely Dichotic? Investigating Dichotic Performance with the Dichotic Digits Difference Test (DDdT) in a Large Clinical Population of Children Referred for an Auditory Processing Assessment. J Am Acad Audiol. 2020 Jan 27;:0 Authors: Cameron S, Dillon H Abstract BACKGROUND: Previous studies in a large population of typically developing (TD) children and a small clinical group showed high correlations between...
Tue Mar 03, 2020 18:08
Related ArticlesEffect of Microphone Location and Beamforming Technology on Speech Recognition in Pediatric Cochlear Implant Recipients. J Am Acad Audiol. 2020 Feb 07;:0 Authors: Holder JT, Taylor AL, Sunderhaus LW, Gifford RH Abstract BACKGROUND: Despite improvements in cochlear implant (CI) technology, pediatric CI recipients continue to have more difficulty understanding speech than their typically hearing peers in background noise. A variety...
Tue Mar 03, 2020 18:08
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