Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.9b01066
Mon Mar 02, 2020 07:00
Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.9b01120
Mon Mar 02, 2020 07:00
Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.9b00239
Mon Mar 02, 2020 07:00
Chemical Research in ToxicologyDOI: 10.1021/acs.chemrestox.9b00363
Mon Mar 02, 2020 07:00
ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00434
Mon Mar 02, 2020 07:00
ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00503
Fri Feb 28, 2020 07:00
ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00528
Fri Feb 28, 2020 07:00
02:52
Abstract Although the role of autophagy has been implicated in several forms of chronic hepatitis, it is still not fully understood. Active autophagy eliminates damaged molecules and organelles (such as mitochondria) by lysosomal degradation. In the present study, we aimed to examine and compare autophagy activity in chronic hepatitis C (CHC) and autoimmune hepatitis (AIH) by detecting the expression of autophagy (LC3 and p62) and mitochondrium-related (TOMM20) proteins, as well...
Mon Mar 02, 2020 02:00
Abstract Background Patients undergoing open abdominopelvic procedures for malignancy are at high risk of postoperative venous thromboembolism (VTE). This risk can be mitigated with prophylaxis; however, optimum duration in this population remains unknown. Our objective was to conduct a systematic review of contemporary literature on the use of heparin thromboprophylaxis following major open pelvic surgery for malignancy, comparing...
02:00
Abstract Epstein‐Barr virus (EBV) is associated with particular forms of gastric cancer (GC). We previously showed that EBV infection into gastric epithelial cells induced aberrant DNA hypermethylation in promoter regions and silencing of tumor suppressor genes. We here conducted integrated analyses of transcriptome and epigenome alteration during EBV infection in gastric cells, to investigate activation of enhancer regions and related transcription factors (TFs) which could contribute to tumorigenesis....
03:06
Abstract Inactivated hemagglutinating virus of Japan envelope (HVJ‐E) have an anti‐tumor effect and tumor immunity. We conducted an open‐label, phase I, dose‐escalation study in patients with castration‐resistant prostate cancer (CRPC) to determine the safety and efficacy of intratumoral and subcutaneous injection of HVJ‐E (GEN0101). Patients with CRPC, who were resistant to or unable to receive standard of care, were included. GEN0101 was injected directly into the prostate and subcutaneously in...
Sun Mar 01, 2020 12:57
Abstract Signal transducer and activator of transcription 3 (STAT3) signaling pathway is a key mediator of cancer cell proliferation, survival and invasion. Aberrant STAT3 has been demonstrated in various malignant cancers. YHO‐1701 is a novel quinolinecarboxamide derivative generated from STX‐0119. Here, we examined the effect of YHO‐1701 on STAT3 and evaluated antitumor activity of YHO‐1701 as a single agent and in combination. YHO‐1701 inhibited STAT3 SH2 binding to phospho‐Tyr peptide selectively...
Sun Mar 01, 2020 12:57
Summary The early detection of non‐small cell lung cancer (NSCLC) remains a common concern. The aim of our study was to validate the diagnostic value of a 7‐autoantibody (7‐AAB) panel compared with radiological diagnosis for NSCLC. We constructed a nomogram and a scoring table based on the 7‐AAB panel’s result to predict the risk of NSCLC. We prospectively enrolled 268 patients who presented with radiological lesions and underwent both the 7‐AAB panel test and pathological diagnosis by surgical...
Sat Feb 29, 2020 12:39
The European Board of Radiology (EBR) has added self-assessment tests for urogenital...Read more on AuntMinnieEurope.comRelated Reading: EBR adds features to EDiR app EBR adds new date to 2020 EDiR exam schedule EBR releases dates for spring 2020 EDiR exams EDiR guidebook now available EBR offers European diploma in Russia
02:23
Imaging software developer Median Technologies has partnered with Assistance...Read more on AuntMinnieEurope.comRelated Reading: Median Technologies signs finance deal Median posts healthy 6-month revenues Median completes restructuring, previews 2018 results Median sees 6-month revenue decline Median appoints new medical director for Europe
02:11
The British Institute of Radiology (BIR) and the Chinese Society of Radiology...Read more on AuntMinnieEurope.comRelated Reading: BIR award to provide aid for conference travel BIR, Siemens offer scholarship for imaging projects BIR: AI will be most positive development in radiology Redla becomes BIR president-elect BIR marks MRI Safety Week
Mon Mar 02, 2020 20:29
Medical device company Alphatec Holdings plans to acquire orthopedic digital...Read more on AuntMinnieEurope.comRelated Reading: EOS brings EOSedge to North America EOS 2019 revenue lags due to dip in orders EOS debuts EOSedge system in Europe, Canada; gets FDA OK EOS reports net loss in 1st half of 2019 EOS secures deal with French radiology group
Mon Mar 02, 2020 19:18
Integrating radiology artificial intelligence (AI) technology into clinical...Read more on AuntMinnieEurope.comRelated Reading: Meet the finalists for EuroMinnies 2020 SIIM, EuSoMII join forces on imaging informatics Utrecht showcases flagship AI infrastructure European societies join in ethical AI statement Video from ECR 2019: Erik Ranschaert on AI training
Mon Mar 02, 2020 09:00
An Imperial College London professor has noted that patients' fear of radiation...Read more on AuntMinnieEurope.comRelated Reading: To shield or not to shield? That's the question BIR supports plan for patient-safe radiation IAEA launches competition for radiation safety BIR releases radiation safety advice sheets BIR, GE partner on radiation safety award
Sat Feb 29, 2020 08:45
Royal Philips, the parent company of Philips Healthcare, and the European Society...Read more on AuntMinnieEurope.comRelated Reading: ESR: Know the facts about the coronavirus ESR announces radio station for ECR 2020 ESR, ERS issue statement on CT lung cancer screening Philips reports Q4 growth, but coronavirus begins to bite Ultrasound drives Q3 growth in Philips imaging division Philips says tariffs will take bite out of Q3 numbers
Fri Feb 28, 2020 20:12
Researchers from China and the Netherlands have found that chest CT proved...Read more on AuntMinnieEurope.comRelated Reading: Italy gears up for spread of coronavirus ESR: Know the facts about the coronavirus What's radiology's role in the coronavirus outbreak? WHO officially names coronavirus disease COVID-19 CT 'paramount' for early diagnosis of novel coronavirus
Fri Feb 28, 2020 09:00
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