Related Articles Depth of invasion determined by magnetic resonance imaging in tongue cancer can be a predictor of cervical lymph node metastasis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 21;: Authors: Haraguchi K, Yoshiga D, Oda M, Tabe S, Mitsugi S, Takahashi O, Habu M, Sasaguri M, Morimoto Y, Yoshioka I, Tominaga K Abstract OBJECTIVES: We evaluated the relationships between depth of invasion (DOI) of tongue cancer, as measured...
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Potential Role of Oxygen-Ozone Therapy in Treatment of COVID-19 Pneumonia. Am J Case Rep. 2020 Aug 17;21:e925849 Authors: Hernández A, Viñals M, Isidoro T, Vilás F Abstract BACKGROUND Pneumonia caused by coronavirus originated in Wuhan, China in late 2019 and has spread around the world, becoming a pandemic. Many patients deteriorate rapidly and require intubation and mechanical ventilation, which is causing the collapse of healthcare systems...
Related Articles Extra-Anatomic Axillofemoral Bypass After Failed Stenting for Aortoiliac-Occlusive Disease in a Patient with Severe Comorbidities. Am J Case Rep. 2020 Aug 17;21:e925009 Authors: Yasa KP, Ryalino C Abstract BACKGROUND An extra-anatomic bypass is the choice of revascularization method for limb salvage in patients with infra-renal aortailiac occlusion accompanied by severe comorbidities. CASE REPORT We report a case of aortailiac-occlusive...
Related Articles Severe Rhabdomyolysis in a 35-Year-old Woman with COVID-19 due to SARS-CoV-2 Infection: A Case Report. Am J Case Rep. 2020 Aug 17;21:e926733 Authors: Alrubaye R, Choudhury H Abstract BACKGROUND Rhabdomyolysis is a skeletal muscle injury that has different etiologies and can be a manifestation of coronavirus disease 2019 (COVID-19). Because it is a life-threatening condition, rapid diagnosis is necessary to prevent acute complications....
Related Articles Renal Transplant Recipient with Concurrent COVID-19 and Stenotrophomonas maltophilia Pneumonia Treated with Trimethoprim/Sulfamethoxazole Leading to Acute Kidney Injury: A Therapeutic Dilemma. Am J Case Rep. 2020 Aug 16;21:e926464 Authors: Mohamed MA, Kaur J, Wani F, Kichloo A, Bhanot R Abstract BACKGROUND Although coronavirus disease 2019 (COVID-19) manifests primarily as a lung infection, its involvement in acute kidney injury...
Related Articles SARS-CoV-2-Associated Acute Hemorrhagic, Necrotizing Encephalitis (AHNE) Presenting with Cognitive Impairment in a 44-Year-Old Woman without Comorbidities: A Case Report. Am J Case Rep. 2020 Aug 16;21:e925641 Authors: Ghosh R, Dubey S, Finsterer J, Chatterjee S, Ray BK Abstract BACKGROUND Acute hemorrhagic necrotizing encephalitis (AHNE) is a rare manifestation of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)...
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Related Articles A case report of management of gastric perforation in situs inversus totalis in a 45-year-old adult. A case report. Int J Surg Case Rep. 2020 Jul 28;74:69-72 Authors: Ouédraogo NLM, Sanogo K, Traoré MS, Simporé J, Traoré SS Abstract INTRODUCTION: Situs inversus is a rare congenital malformation often discovered during childhood. It can cause diagnosis errors in adulthood. Its association with gastric perforation is an extremely...
Related Articles Simultaneous bilateral traumatic facial palsy with different treatment protocols. Int J Surg Case Rep. 2020 Jul 28;74:66-68 Authors: Ardhaoui H, Halily S, Abada R, Rouadi S, Roubal M, Mahtar M Abstract INTRODUCTION: Bilateral simultaneous facial palsy is a rare clinical entity. Traumatic origin is even rarer. Long-term sequelae are disabling. Therefore, rapid and adequate management is crucial. CASE PRESENTATION: Herein...
Related Articles Wide resection giant cell tumor of distal ulna and stabilization ulnar stump with extensor Carpi ulnaris tendon (2 case reports). Int J Surg Case Rep. 2020 Jul 28;74:58-62 Authors: Mujaddid I, Pamudji U, Savero I, Handry T, Brian W Abstract INTRODUCTION: Giant-cell tumor (GCT) of bone occurred in the distal end of the ulna is extremely uncommon. Wide resection is usually indicated in such cases and at times it may be necessary...
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Real-World Effectiveness and Safety of Field- and Lesion-Directed Treatments for Actinic Keratosis. J Drugs Dermatol. 2020 Aug 01;19(8):756-762 Authors: Hansen JB, Larsson T, Dunkelly-Allen N, Veverka KA, Feldman SR Abstract Background: Real-world data for actinic keratosis treatment in the United States is lacking. Objectives: To understand real-world treatment patterns for actinic keratosis by type and modality, and compare effectiveness...
The 1440 nm and 1927 nm Nonablative Fractional Diode Laser: Current Trends and Future Directions. J Drugs Dermatol. 2020 Aug 01;19(8):s3-11 Authors: Friedman PM, Polder KD, Sodha P, Geronemus RG Abstract Clinical characteristics of skin exposed to ultraviolet and infrared radiation include dryness, dyschromia, laxity, roughness, sallowness, scaling, telangiectasia, and wrinkles. Fractional photothermolysis promotes skin remodeling by formation...
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Related Articles Surgical Management of Carotid Body Tumor and Risk Factors of Postoperative Cranial Nerve Injury. World J Surg. 2020 Aug 17;: Authors: Jiang X, Fang G, Guo D, Xu X, Chen B, Jiang J, Dong Z, Fu W Abstract BACKGROUND: To identify risk factors of postoperative cranial nerve injury (CNI) following surgical treatment of a carotid body tumor (CBT) by retrospective analysis of the data during the past decade in our center. ...
Related Articles The Post COVID-19 Surgical Backlog: Now is the Time to Implement Enhanced Recovery After Surgery (ERAS). World J Surg. 2020 Aug 14;: Authors: Ljungqvist O, Nelson G, Demartines N PMID: 32803298 [PubMed - as supplied by publisher]
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Subarachnoid osteoma of the right frontal lobe: A case report. World Neurosurg. 2020 Aug 14;: Authors: Cao X, Wang Y, Jin Y Abstract BACKGROUND: Intracranial osteoma (ICO), arising from none-osseous tissue and surrounding by brain parenchyma, is extremely rare. CASE PRESENTATION: We report an ICO surgical case of none heterotopic ossification risk factor in a 32 years old female who presented the chief complaint was headache, vertigo...
First report of a pineal cyst associated with corpus callosum lipoma. World Neurosurg. 2020 Aug 14;: Authors: Bozier E, Carpentier A, Apra C PMID: 32805468 [PubMed - as supplied by publisher]
Treatment and outcomes of iatrogenic cerebrospinal fluid leak caused by different surgical procedures. World Neurosurg. 2020 Aug 14;: Authors: Tang R, Mao S, Li D, Ye H, Zhang W Abstract BACKGROUND: Iatrogenic cerebrospinal fluid (CSF) leaks are associated with serious sequelae. We analyzed the causes, complications, treatments, and outcomes of iatrogenic CSF leaks. Furthermore, the comorbidities and outcomes between timely and delayed repairs...
COVID-19's Impact on Neurosurgical Training in Southeast Asia. World Neurosurg. 2020 Aug 14;: Authors: Wittayanakorn N, Weng Nga VD, Sobana M, Ahmad Bahuri NF, Baticulon RE Abstract OBJECTIVE: Neurosurgery departments worldwide have been forced to restructure their training programs due to the coronavirus disease 2019 (COVID-19) pandemic. In this study, we describe the impact of COVID-19 on neurosurgical training in Southeast Asia. ...
Neurological Complications of Preoperative Embolization of Spinal Metastasis: A Systemic Review of the Literature Identifying Distinct Mechanisms of Injury. World Neurosurg. 2020 Aug 14;: Authors: Houten JK, Swiggett SJ, Hadid B, Choueka DM, Kinon MD, Buciuc R, Zumofen DW Abstract BACKGROUND: Preoperative embolization of spinal metastases may improve outcome of resection by reducing surgical blood loss and operative time. Neurological complications...
Complete Obliteration of a Foramen Magnum Dural Arteriovenous Fistula by Microsurgery After Failed Endovascular Treatment Using Onyx: Case Report and Literature Review. World Neurosurg. 2020 Aug 14;: Authors: Kakizaki S, Ishibashi T, Kato N, Kan I, Nishimura K, Murayama Y Abstract BACKGROUND: Foramen magnum dural arteriovenous fistula (DAVF) is a rare disease, with some reported cases of successful treatment. We achieved complete obliteration...
The Intradural Pathology causing Cerebrospinal Fluid Obstruction in Syringomyelia and Effectiveness of Foramen Magnum and Magendie Dredging Treatment. World Neurosurg. 2020 Aug 14;: Authors: Guan J, Yuan C, Zhang C, Ma L, Yao Q, Cheng L, Liu Z, Wang K, Duan W, Wang X, Wu H, Chen Z, Jian F Abstract PURPOSE: By summarizing the pathological changes in the intradural region of the craniocervical junction in patients with syringomyelia and the pathophysiological...
Related Articles Anatomy and White Matter Connections of the Inferior Temporal Gyrus. World Neurosurg. 2020 Aug 13;: Authors: Lin YH, Young IM, Conner AK, Glenn CA, Chakraborty AR, Nix CE, Bai MY, Dhanaraj V, Fonseka RD, Hormovas J, Tanglay O, Briggs RG, Sughrue ME Abstract INTRODUCTION: The inferior temporal gyrus (ITG) is known to be involved in high-cognitive functions, including visual and language comprehensions and emotion regulation....
Related Articles Concurrent vs Staged Procedures for VPS and Cranioplasty: A 10-year Retrospective Comparative Analysis of Surgical Outcomes. World Neurosurg. 2020 Aug 13;: Authors: Rosinski CL, Behbahani M, Geever B, Chaker AN, Patel S, Chiu R, Zakrzewski J, Rosenberg D, Parola R, Shah K, Mehta AI PMID: 32798784 [PubMed - as supplied by publisher]
Related Articles Response to surgical triage in an evolving pandemic based on disease classification and predictive modelling. World Neurosurg. 2020 Aug 13;: Authors: Lewkonia P PMID: 32798783 [PubMed - as supplied by publisher]
Related Articles Adersson lesion occurred in the lumbosacral segment of a young man: A case report and literature review. World Neurosurg. 2020 Aug 13;: Authors: Qin W, Yang P, Zhou F, Mao H, Yang H Abstract Andersson lesion (AL) is not a rare complication of ankylosing spondylitis (AS) ,but it seldom occurs in single lumbosacral segment or young people. In our case, the young AS patient suffered from AL between L5 and S1 and underwent surgical...
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MicroRNAs in breast cancer: New maestros defining the melody. Cancer Genet. 2020 Aug 07;246-247:18-40 Authors: Khalife H, Skafi N, Fayyad-Kazan M, Badran B Abstract MicroRNAs, short non-coding single-stranded RNAs, are important regulators and gatekeepers of the coding genes in the human genome. MicroRNAs are highly conserved among species and expressed in different tissues and cell types. They are involved in almost all the biological...
YAN, a novel microtubule inhibitor, inhibits P-gp and MRP1 function and induces mitotic slippage followed by apoptosis in multidrug-resistant A549/Taxol cells. Toxicol In Vitro. 2020 Aug 14;:104971 Authors: Gao M, Liu T, Li J, Guan Q, Wang H, Yan S, Li Z, Zuo D, Zhang W, Wu Y Abstract Lung cancer is the most common cause of cancer-related death worldwide. The occurrence of multidrug resistance (MDR) affects the therapeutic efficacy of...
Simple method for fabrication of metal-organic framework within a carboxymethylcellulose/graphene quantum dots matrix as a carrier for anticancer drug. Int J Biol Macromol. 2020 Aug 14;: Authors: Pooresmaeil M, Namazi H, Salehi R Abstract Biocompatible drug delivery vehicles with sustained drug release property are valuable in cancer therapy and can reduce some of the side effects. Hence, to achieve the biocompatible system with sustained...
Dual targeting of EZH2 and androgen receptor as a novel therapy for castration-resistant prostate cancer. Toxicol Appl Pharmacol. 2020 Aug 14;:115200 Authors: Shankar E, Franco D, Iqbal O, Moreton S, Kanwal R, Gupta S Abstract Castration-resistant prostate cancer (CRPC) emerges after androgen withdrawal therapy and remains incurable due to the lack of effective treatment protocols. Treatment with enzalutamide, a second generation androgen...
Gambogic acid potentiates gemcitabine induced anticancer activity in non-small cell lung cancer. Eur J Pharmacol. 2020 Aug 14;:173486 Authors: Hatami E, Nagesh PKB, Jaggi M, Chauhan SC, Yallapu MM Abstract Non-small cell lung cancer (NSCLC) is the most frequent type of lung cancer accounting up to 80-85% of all lung cancer cases. Gemcitabine (Gem), a pyrimidine nucleoside antimetabolite, is widely used chemotherapy offering several months...
Omipalisib Inhibits Esophageal Squamous Cell Carcinoma Growth Through Inactivation of Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) and ERK Signaling. Med Sci Monit. 2020 Aug 17;26:e927106 Authors: Zhu DS, Dong JY, Xu YY, Zhang XT, Fu SB, Liu W Abstract BACKGROUND Esophageal squamous cell carcinoma (ESCC) is a life-threatening digestive tract malignancy with no known curative treatment. This study aimed to investigate...
Cell Models for Birth Defects Caused by Chloroethylnitrosourea-induced DNA Lesions. J Craniofac Surg. 2020 Aug 13;: Authors: Cao J, Liu Z, Wang C, Wang J, Pan B, Qie S Abstract Birth defects have been linked to administration of alkylating agents during pregnancy. The anti-tumor efficacy of alkylating agents correlate with their ability to induce DNA lesions, especially interstrand crosslinks (ICLs). Yet the role of DNA damages in birth...
Upconverting Nanocarriers Enable Triggered Microtubule Inhibition and Concurrent Ferroptosis Induction for Selective Treatment of Triple-Negative Breast Cancer. Nano Lett. 2020 Aug 17;: Authors: Zhu J, Dai P, Liu F, Li Y, Qin Y, Yang Q, Tian R, Fan A, Medeiros SF, Wang Z, Zhao Y Abstract Despite the resistance of triple-negative breast cancer (TNBC) to targeted hormone therapy, the discovery of azobenzene combretastatin A4 (Azo-CA4) provides...
Related Articles The synergistic anticancer effects of ReoT3D, CPT-11, and BBI608 on murine colorectal cancer cells. Daru. 2020 Aug 15;: Authors: Babaei A, Soleimanjahi H, Soleimani M, Arefian E Abstract BACKGROUND: Many types of oncolytic viruses (OVs) were enrolled in clinical trials. Recently, an OV named Talimogene laherparepvec approved for the treatment of melanoma. This achievement highlighted the clinical application of OVs. Scientists...
Related Articles Phloretin Modulates Human Th17/Treg Cell Differentiation In Vitro via AMPK Signaling. Biomed Res Int. 2020;2020:6267924 Authors: Jiao A, Yang Z, Fu X, Hua X Abstract Objective: We conducted studies to explore the effect of phloretin on glucose uptake, proliferation, and differentiation of human peripheral blood CD4+ T cells and investigated the mechanism of phloretin on inducing Th17/Treg development. Methods:...
Related Articles Proteasome Inhibition by Carfilzomib Induced Apotosis and Autophagy in a T-cell Acute Lymphoblastic Leukemia Cell Line. Iran J Pharm Res. 2019;18(Suppl1):132-145 Authors: Hosseini MS, Mohammadi MH, Vahabpour Roudsari R, Jafari L, Mashati P, Gharehbaghian A Abstract T-cell acute lymphoblastic leukemia is an aggressive hematologic malignancy which is usually associated with unfavorable prognosis particularly in patients with...
Related Articles CDK Blockade Using AT7519 Suppresses Acute Myeloid Leukemia Cell Survival through the Inhibition of Autophagy and Intensifies the Anti-leukemic Effect of Arsenic Trioxide. Iran J Pharm Res. 2019;18(Suppl1):119-131 Authors: Zabihi M, Safaroghli-Azar A, Gharehbaghian A, Allahbakhshian Farsani M, Bashash D Abstract The strong storyline behind the critical role of cyclin-dependent kinase (CDK) inhibitor proteins in natural...
Circ_0000885 Enhances Osteosarcoma Progression by Increasing FGFR1 Expression via Sponging MiR-1294.
Related Articles Circ_0000885 Enhances Osteosarcoma Progression by Increasing FGFR1 Expression via Sponging MiR-1294. Cancer Manag Res. 2020;12:6441-6452 Authors: Chen Y, Zhang S, Bai C, Guan Z, Chen W Abstract Background: As a malignant tumor, the progression of osteosarcoma (OS) is mediated by multiple regulators, including circular RNAs (circRNAs). However, the role of circ_0000885 in OS is unclear. Materials and Methods: Quantitative...
Related Articles miR-96-5p Suppresses the Progression of Nasopharyngeal Carcinoma by Targeting CDK1. Onco Targets Ther. 2020;13:7467-7477 Authors: Luo X, He X, Liu X, Zhong L, Hu W Abstract Background: Nasopharyngeal carcinoma (NPC) is a malignant tumor that occurs in the nasopharyngeal mucosa. Clinically, radiotherapy is the preferred treatment for NPC, and cervical lymph node metastasis is easy to emerge in the early stage. Therefore,...
Related Articles 3,6-Disubstituted 1,2,4-Triazolo[3,4-b]Thiadiazoles with Anticancer Activity Targeting Topoisomerase II Alpha. Onco Targets Ther. 2020;13:7369-7386 Authors: Sagredou S, Dalezis P, Nikoleousakos N, Nikolaou M, Voura M, Almpanakis K, Panayiotidis MI, Sarli V, Trafalis DT Abstract Background: Topoisomerase IIα (topIIα) maintains the topology of DNA in order to ensure the proper functioning of numerous DNA processes. Inhibition...
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