Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectivesMost Chinese hospitals have customized environmental cleaning policies and systems, with limited data availability based on evidence-based medicine. This study investigated the relationship between multidrug-resistant organism (MDRO) colonization in intensive care unit (ICU) patients and ICU surface bacterial contamination status.MethodsThis cross-sectional study comprised MDRO screening in ICU patients using bacterial...
Fri Aug 21, 2020 12:02
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study was performed to determine the risk factors associated with intensive care unit delirium (ICUD) in patients undergoing invasive mechanical ventilation (IMV) secondary to acute exacerbation of chronic obstructive pulmonary disease (COPD).MethodsData involving 620 patients undergoing IMV secondary to acute exacerbation of COPD from 2009 to 2019 at the First Hospital of Hebei Medical University were retrospectively...
Fri Aug 21, 2020 10:21
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveSirolimus has been used to treat paediatric kaposiform haemangioendothelioma patients. However, there is considerable pharmacokinetic variability among individuals, and it is difficult to develop an initial dosing regimen. The goal of the present study is to recommend an initial sirolimus dose in paediatric kaposiform haemangioendothelioma patients based on population pharmacokinetics and pharmacogenomics.MethodsThis...
Thu Aug 20, 2020 15:56
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study aimed to determine the importance of biomarkers of chronic heart failure (CHF) for assessing disease severity in euvolemic stable patients.Patients and methodsN-terminal pro-B-type natriuretic peptide (NT-proBNP), growth differentiation factor (GDF)-15, galectin-3, cystatin-C, soluble suppression of tumorigenicity 2 (sST2), tissue type inhibitor of matrix metalloproteinase (TIMP)-1, and ceruloplasmin levels...
Thu Aug 20, 2020 13:23
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study was performed to investigate the clinical features, risk factors, and outcomes of bone and joint tuberculosis in patients undergoing dialysis.MethodsWe systematically reviewed the medical records of 17 patients with bone and joint tuberculosis undergoing dialysis who were admitted to our hospital from January 2009 to January 2019.ResultsSeventeen patients with bone and joint tuberculosis undergoing dialysis...
Thu Aug 20, 2020 13:22
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo evaluate the efficacy of the figure-of-eight (FOE) suture technique in the treatment of tunnel bleeding after femoral artery puncture compared with manual compression (MC).MethodsThis prospective, randomized, controlled study enrolled patients that had received transfemoral coronary artery angiography or percutaneous coronary intervention and then developed tunnel bleeding. They were randomly assigned into two...
Thu Aug 20, 2020 13:22
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Chronic obstructive pulmonary disease (COPD) is a disease with increasing prevalence and burden for health systems worldwide. Every country collects its own epidemiological data regarding COPD prevalence, morbidity and mortality while taking steps to educate the population and medical community to improve early detection and treatment. The rising COPD prevalence creates a need for comprehensive guidelines. In 2012 and 2017–2018,...
Thu Aug 20, 2020 13:22
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveMicrovascular invasion is shown to be an independent risk factor for liver cancer recurrence. Timely treatment may reduce the recurrence rate and prolong total survival time. The aim of this study was to investigate the effectiveness of sorafenib in treating patients with hepatocellular carcinoma (HCC) and microvascular invasionMethodsA comprehensive literature search was conducted in PubMed, EMBASE, MEDLINE, web...
Thu Aug 20, 2020 13:22
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study aimed to evaluate the effect of clearing heat and resolving phlegm for acute exacerbation of chronic obstructive pulmonary disease with the syndrome of phlegm-heat obstruction of the lung.MethodsThis was a real-world retrospective cohort study of inpatients at our institution from 1 January 2015 to 31 December 2017. The patients were divided into two groups according to whether they received oral traditional...
Thu Aug 20, 2020 11:52
Journal of International Medical Research, Volume 48, Issue 8, August 2020. A 51-year-old woman visited our hospital with a chief complaint of an abnormal chest shadow in the right lung detected during a routine annual check-up. Chest computed tomography showed a 14-mm ground-glass opacity in the right upper lobe, suspicious for lung cancer. At the same time, a tracheal bronchus originating directly from the trachea was observed. In addition to the tracheal bronchus, a pulmonary vein variation running...
Thu Aug 20, 2020 11:32
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveWe examined whether antiplatelet therapy is safe for ischemic stroke patients with cerebral microbleed.MethodsWe retrospectively analyzed ischemic stroke patients admitted to our hospital from 2015 to 2018. Baseline information was extracted from the computerized database. Adverse events, including symptomatic cerebral hemorrhage, recurrent cerebral infarction, and death, were collected by phone.ResultsA total of...
Thu Aug 20, 2020 11:32
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo investigate the visibility of peripheral pulmonary arteries by computed tomography pulmonary angiography (CTPA) and image quality using a free-breathing combined with a high-threshold bolus triggering technique and to explore the feasibility of this technique in pulmonary embolism (PE) patients who cannot hold their breath.MethodsPatients with suspected PE who underwent CTPA (n=240) were randomly assigned to two...
Thu Aug 20, 2020 11:32
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveIn recent years, a number of case–control studies have focused on the association between the DJ-1 g.168_185del polymorphism and the risk of Parkinson's disease (PD). However, the results have been conflicting. To estimate the relationship between the DJ-1 g.168_185del polymorphism and PD susceptibility, a comprehensive meta-analysis was performed.MethodsEligible studies concerning the DJ-1 g.168_185del polymorphism...
Thu Aug 20, 2020 11:31
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveMissed Monteggia fractures are commonly observed among children. Both the interval from the injury to surgery and the patient’s age at operation are thought to be correlated directly with the success of the surgery and prognosis. The aim of the present work was to report one interesting adult case of a missed Monteggia fracture with an intact annular ligament 9 years after injury and the outcomes at a 7-year follow-up.Case...
Thu Aug 20, 2020 11:31
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Colorectal cancer (CRC) is a leading cause of cancer death worldwide. Recent advances in genomic medicine have identified novel gene mutations that contribute to an increased risk of CRC. Here, we describe a diagnosis of colon cancer in a 63-year-old woman and also in her brother. Next-generation sequencing showed that both patients harbored a germline mutation in NF1. The female patient also carried co-mutations in KRAS...
Thu Aug 20, 2020 11:31
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo investigate the accuracy of derecruitment volume (VDER) assessed by pressure–impedance (P-I) curves derived from electrical impedance tomography (EIT).MethodsSix pigs with acute lung injury received decremental positive end-expiratory pressure (PEEP) from 15 to 0 in steps of 5 cmH2O. At the end of each PEEP level, the pressure–volume (P-V) curves were plotted using the low constant flow method and release maneuvers...
Thu Aug 20, 2020 09:43
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