IJMS, Vol. 21, Pages 6014: Targeting the Mitochondrial Metabolic Network: A Promising Strategy in Cancer Treatment International Journal of Molecular Sciences doi: 10.3390/ijms21176014 Authors: Luca Frattaruolo Matteo Brindisi Rosita Curcio Federica Marra Vincenza Dolce Anna Rita Cappello Metabolic reprogramming is a hallmark of cancer, which implements a profound metabolic rewiring in order to support a high proliferation rate and to ensure cell survival in its complex...
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IJNS, Vol. 6, Pages 67: Newborn Screening for Congenital Adrenal Hyperplasia: Review of Factors Affecting Screening Accuracy International Journal of Neonatal Screening doi: 10.3390/ijns6030067 Authors: Patrice K. Held Ian M. Bird Natasha L. Heather Newborn screening for 21-hydroxylase deficiency (21OHD), the most common form of congenital adrenal hyperplasia, has been performed routinely in the United States and other countries for over 20 years. Screening provides the opportunity...
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JCM, Vol. 9, Pages 2720: Self-Efficacy and Clinical Characteristics in Casual Gamers Compared to Excessive Gaming Users and Non-Gamers in Young Adults Journal of Clinical Medicine doi: 10.3390/jcm9092720 Authors: Sun Ju Chung Joon Hwan Jang Ji Yoon Lee Aruem Choi Bo Mi Kim Min Kyung Park Myung Hun Jung Jung-Seok Choi This study investigated differences in the self-efficacy and clinical characteristics which were found relevant to addictive behaviors in young adults...
JCM, Vol. 9, Pages 2719: Increased First Pass Success with C-MAC Videolaryngoscopy in Prehospital Endotracheal Intubation—A Randomized Controlled Trial Journal of Clinical Medicine doi: 10.3390/jcm9092719 Authors: Christian Macke Felix Gralla Marcel Winkelmann Jan-Dierk Clausen Marco Haertle Christian Krettek Mohamed Omar Endotracheal intubation (ETI) with direct view laryngoscopy (DL) is the gold standard for airway management. Videolaryngoscopy (VL) can improve glottis...
JCM, Vol. 9, Pages 2718: Neural Networks to Predict Radiographic Brain Injury in Pediatric Patients Treated with Extracorporeal Membrane Oxygenation Journal of Clinical Medicine doi: 10.3390/jcm9092718 Authors: Neel Shah Abdelaziz Farhat Jefferson Tweed Ziheng Wang Jeon Lee Rafe McBeth Michael Skinner Fenghua Tian Ravi Thiagarajan Lakshmi Raman Brain injury is a significant source of morbidity and mortality for pediatric patients treated with Extracorporeal...
JCM, Vol. 9, Pages 2716: COVID-19 Pandemic Outbreak and its Psychological Impact on Patients with Rare Lysosomal Diseases Journal of Clinical Medicine doi: 10.3390/jcm9092716 Authors: Agata Fiumara Giuseppina Lanzafame Alessia Arena Annamaria Sapuppo Federica Raudino Andrea Praticò Piero Pavone Rita Barone Background: Lysosomal storage disorders (LSDs) are rare, chronic, progressive multisystem diseases implying severe medical issues and psychological burden. Some...
JCM, Vol. 9, Pages 2715: Additional Value of 2-[18F]FDG PET/CT Comparing to MRI in Treatment Approach of Anal Cancer Patients Journal of Clinical Medicine doi: 10.3390/jcm9092715 Authors: Reyhaneh Manafi-Farid Alexander Kupferthaler Helwig Wundsam Georg Gruber Reza Vali Clemens Venhoda Christine Track Ali Beheshti Werner Langsteger Hans Geinitz Mohsen Beheshti Accurate staging and treatment planning are imperative for precise management in Anal Cancer (ACa)...
JCM, Vol. 9, Pages 2717: Intracranial Hemorrhage Complicating Acute Myocardial Infarction: An 18-Year National Study of Temporal Trends, Predictors, and Outcomes Journal of Clinical Medicine doi: 10.3390/jcm9092717 Authors: Sri Harsha Patlolla Pranathi R. Sundaragiri Wisit Cheungpasitporn Rajkumar Doshi Gregory W. Barsness Alejandro A. Rabinstein Allan S. Jaffe Saraschandra Vallabhajosyula Background: There is a paucity of contemporary data on the burden of intracranial...
JCM, Vol. 9, Pages 2713: Low Body Weight Increases the Risk of Ischemic Stroke and Major Bleeding in Atrial Fibrillation: The COOL-AF Registry Journal of Clinical Medicine doi: 10.3390/jcm9092713 Authors: Rungroj Krittayaphong Ply Chichareon Chulalak Komoltri Sakaorat Kornbongkotmas Ahthit Yindeengam Gregory Y. H. Lip We aimed to determine if low body weight (LBW) status (<50 kg) is independently associated with increased risk of ischemic stroke and bleeding in...
JCM, Vol. 9, Pages 2714: Genotype–Phenotype Correlations in Children with HHT Journal of Clinical Medicine doi: 10.3390/jcm9092714 Authors: Alexandra Kilian Giuseppe Latino Andrew White Dewi Clark Murali Chakinala Felix Ratjen Jamie McDonald Kevin Whitehead James Gossage Doris Lin Katharine Henderson Jeffrey Pollak Justin McWilliams Helen Kim Michael Lawton Marie Faughnan the Brain Vascular Malformation Consortium HHT Investigator Group ...
JCM, Vol. 9, Pages 2709: Glucocorticoids in Systemic Lupus Erythematosus. Ten Questions and Some Issues Journal of Clinical Medicine doi: 10.3390/jcm9092709 Authors: Sabrina Porta Alvaro Danza Maira Arias Saavedra Adriana Carlomagno María Cecilia Goizueta Florencia Vivero Guillermo Ruiz-Irastorza Since the discovery of glucocorticoids (GCs), their important anti-inflammatory effect, rapid mechanism of action, low cost, and accessibility have made them one of the mainstays...
JCM, Vol. 9, Pages 2712: Prolonged QT Interval in SARS-CoV-2 Infection: Prevalence and Prognosis Journal of Clinical Medicine doi: 10.3390/jcm9092712 Authors: Núria Farré Diana Mojón Marc Llagostera Laia C. Belarte-Tornero Alicia Calvo-Fernández Ermengol Vallés Alejandro Negrete Marcos García-Guimaraes Yolanda Bartolomé Camino Fernández Ana B. García-Duran Jaume Marrugat Beatriz Vaquerizo Background: The prognostic value of a prolonged QT interval...
JCM, Vol. 9, Pages 2710: Active Smoking Before Liver Transplantation in Patients with Alcohol Use Disorder: Risk Factors and Outcomes Journal of Clinical Medicine doi: 10.3390/jcm9092710 Authors: Ana Isabel López-Lazcano Antoni Gual Jordi Colmenero Elsa Caballería Anna Lligoña Miquel Navasa Gonzalo Crespo Eva López Hugo López-Pelayo Tobacco use is more prevalent among alcohol liver disease (ALD) transplant patients and exerts harmful effects to the patient and...
JCM, Vol. 9, Pages 2708: Dynamic Risk Stratification for Predicting Treatment Response in Differentiated Thyroid Cancer Journal of Clinical Medicine doi: 10.3390/jcm9092708 Authors: Evanthia Giannoula Christos Melidis Nikitas Papadopoulos Panagiotis Bamidis Vasilios Raftopoulos Ioannis Iakovou Prognosis in Differentiated Thyroid Cancer (DTC) patients is excellent, but a significant degree of overtreatment still exists because of the inability to accurately identify small...
JCM, Vol. 9, Pages 2711: Oxidative Stress Markers and the Retinopathy of Prematurity Journal of Clinical Medicine doi: 10.3390/jcm9092711 Authors: Graziosi Perrotta Russo Gasparroni D’Egidio Marinelli Di Marzio Falconio Mastropasqua Li Volti Mangifesta Gazzolo Retinopathy of prematurity (ROP) is a leading cause of potentially preventable blindness in low birth weight preterm infants. Several perinatal and postnatal factors contribute to the...
JCM, Vol. 9, Pages 2706: CFTR Modulators: Impact on Fertility, Pregnancy, and Lactation in Women with Cystic Fibrosis Journal of Clinical Medicine doi: 10.3390/jcm9092706 Authors: Jennifer L. Taylor-Cousar Cystic fibrosis (CF) is a life-shortening genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. These mutations lead to abnormal ion transport in mucous membranes throughout the body, including in the respiratory and gastrointestinal...
JCM, Vol. 9, Pages 2707: Materno-Fetal and Neonatal Complications of Diabetes in Pregnancy: A Retrospective Study Journal of Clinical Medicine doi: 10.3390/jcm9092707 Authors: Giampiero Capobianco Alessandra Gulotta Giulio Tupponi Francesco Dessole Maddalena Pola Giuseppe Virdis Marco Petrillo Valerio Mais Giorgio Olzai Roberto Antonucci Laura Saderi Pier Luigi Cherchi Salvatore Dessole Giovanni Sotgiu The aim of this case–control study...
JCM, Vol. 9, Pages 2705: Additional Mosapride to Proton Pump Inhibitor for Gastroesophageal Reflux Disease: A Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9092705 Authors: Toshihiro Nishizawa Kiyoto Mori Shuntaro Yoshida Hirotoshi Ebinuma Osamu Toyoshima Hidekazu Suzuki Background and Aim: In gastroesophageal reflux disease (GERD), the additive effect of mosapride to a proton pump inhibitor (PPI) is still controversial. This meta-analysis integrated randomized...
JCM, Vol. 9, Pages 2704: Effect of Angle Opening Parameters on Corneal Endothelial Cell Density and Intraocular Pressure after Posterior Chamber Phakic Intraocular Lens Implantation Journal of Clinical Medicine doi: 10.3390/jcm9092704 Authors: Kazutaka Kamiya Wakako Ando Tatsuhiko Tsujisawa Masahide Takahashi Nobuyuki Shoji This study aimed to investigate the time courses of angle opening parameters and the relationships of these with the corneal endothelial cell density...
JCM, Vol. 9, Pages 2703: Epidemiology and Comorbidities of Excoriation Disorder: A Retrospective Case-Control Study Journal of Clinical Medicine doi: 10.3390/jcm9092703 Authors: Christina Kwon Nishadh Sutaria Raveena Khanna Erik Almazan Kyle Williams Noori Kim Sarina Elmariah Shawn G. Kwatra Excoriation disorder is a psychocutaneous disorder characterized by repetitive skin-picking and associated with significant morbidity. Currently, epidemiological data in patients...
JCM, Vol. 9, Pages 2702: Hepatitis C Clearance by Direct-Acting Antivirals Impacts Glucose and Lipid Homeostasis Journal of Clinical Medicine doi: 10.3390/jcm9092702 Authors: Christiana Graf Tania Welzel Dimitra Bogdanou Johannes Vermehren Anita Beckel Jörg Bojunga Mireen Friedrich-Rust Julia Dietz Alica Kubesch Antonia Mondorf Sarah Fischer Thomas Lutz Philipp Stoffers Eva Herrmann Thierry Poynard Stefan Zeuzem Georg Dultz Ulrike Mihm ...
JCM, Vol. 9, Pages 2701: Snail-1 Overexpression Correlates with Metastatic Phenotype in BRAFV600E Positive Papillary Thyroid Carcinoma Journal of Clinical Medicine doi: 10.3390/jcm9092701 Authors: Katarzyna Wieczorek-Szukala Janusz Kopczynski Aldona Kowalska Andrzej Lewinski The ability of cancer to metastasize is regulated by various signaling pathways, including transforming growth factor β (TGFβ), also implicated in the upregulation of Snail-1 transcription...
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JFMK, Vol. 5, Pages 65: Human Dental Pulp Tissue during Orthodontic Tooth Movement: An Immunofluorescence Study Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5030065 Authors: Giovanna Vermiglio Antonio Centofanti Giovanni Matarese Angela Militi Marco Matarese Alba Arco Fabiana Nicita Giuseppina Cutroneo The orthodontic tooth movement is the last step of several biological processes that take place after the application of external forces. During...
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JoF, Vol. 6, Pages 144: Phylogenetic and Chemotaxonomic Studies Confirm the Affinities of Stromatoneurospora phoenix to the Coprophilous Xylariaceae Journal of Fungi doi: 10.3390/jof6030144 Authors: Kevin Becker Sarunyou Wongkanoun Anna-Charleen Wessel Gerald F. Bills Marc Stadler J. Jennifer Luangsa-ard The genus Stromatoneurospora was erected in 1973 by Jong and Davis to accommodate the pyrophilic pyrenomycete Sphaeria phoenix and has traditionally been placed in the...
JoF, Vol. 6, Pages 143: Differential Regulation of Echinocandin Targets Fks1 and Fks2 in Candida glabrata by the Post-Transcriptional Regulator Ssd1 Journal of Fungi doi: 10.3390/jof6030143 Authors: Kelley R. Healey Padmaja Paderu Xin Hou Cristina Jimenez Ortigosa Nicole Bagley Biren Patel Yanan Zhao David S. Perlin Invasive infections caused by the opportunistic pathogen Candida glabrata are treated with echinocandin antifungals that target β-1,3-glucan synthase,...
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J. Imaging, Vol. 6, Pages 82: Detection of HER2 from Haematoxylin-Eosin Slides Through a Cascade of Deep Learning Classifiers via Multi-Instance Learning Journal of Imaging doi: 10.3390/jimaging6090082 Authors: David La Barbera Kevin Roitero Vincenzo Della Mea Breast cancer is the most frequently diagnosed cancer in woman. The correct identification of the HER2 receptor is a matter of major importance when dealing with breast cancer: an over-expression of HER2 is associated with...
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JPM, Vol. 10, Pages 98: Circulating MicroRNAs as Prognostic and Therapeutic Biomarkers in Breast Cancer Molecular Subtypes Journal of Personalized Medicine doi: 10.3390/jpm10030098 Authors: Veronica Zelli Chiara Compagnoni Roberta Capelli Katia Cannita Tina Sidoni Corrado Ficorella Carlo Capalbo Francesca Zazzeroni Alessandra Tessitore Edoardo Alesse Breast cancer (BC) is a common and heterogeneous disease, of which six molecular subtypes, characterized by...
JPM, Vol. 10, Pages 97: Benefit of Wearing an Activity Tracker in Sarcoidosis Journal of Personalized Medicine doi: 10.3390/jpm10030097 Authors: Marjolein Drent Marjon Elfferich Ellen Breedveld Jolanda De Vries Bert Strookappe Sarcoidosis causes many disabling symptoms, including fatigue and exercise limitations, which have been shown to improve by physical activity programs. The aim of this study was to estimate the effect of continuous activity monitoring using an electronic...
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Life, Vol. 10, Pages 161: Modelling Dose Effects from Space Irradiations: Combination of High-LET and Low-LET Radiations with a Modified Microdosimetric Kinetic Model Life doi: 10.3390/life10090161 Authors: Alejandro Bertolet Alejandro Carabe The Microdosimetric Kinetic Model (MKM) to predict the effects of ionizing radiation on cell colonies is studied and reformulated for the case of high-linear energy transfer (LET) radiations with a low dose. When the number of radiation events...
Life, Vol. 10, Pages 160: Impact of Mitochondrial DNA Mutations on Carotid Intima-Media Thickness in the Novosibirsk Region Life doi: 10.3390/life10090160 Authors: Tatiana V. Kirichenko Anastasia I. Ryzhkova Vasily V. Sinyov Marina D. Sazonova Varvara A. Orekhova Vasily P. Karagodin Elena V. Gerasimova Mikhail I. Voevoda Alexander N. Orekhov Yulia I. Ragino Igor A. Sobenin Margarita A. Sazonova The search for markers of predisposition to atherosclerosis...
Life, Vol. 10, Pages 159: Changes in the Plantar Flexion Torque of the Ankle and in the Morphological Characteristics and Mechanical Properties of the Achilles Tendon after 12-Week Gait Retraining Life doi: 10.3390/life10090159 Authors: Liqin Deng Xini Zhang Songlin Xiao Yang Yang Lu Li Weijie Fu Purpose: Although the Achilles tendon (AT) is the largest and strongest tendon, it remains one of the most vulnerable tendons among elite and recreational runners. The present...
Life, Vol. 10, Pages 158: One-Seventh of Patients with COVID-19 Had Olfactory and Gustatory Abnormalities as Their Initial Symptoms: A Systematic Review and Meta-Analysis Life doi: 10.3390/life10090158 Authors: Hsin Chi Nan-Chang Chiu Chun-Chih Peng Chao-Hsu Lin Yu-Lin Tai Ming-Dar Lee Yu-Jyun Cheng Boon Fatt Tan Chien-Yu Lin Coronavirus disease 2019 (COVID-19) patients exhibited protean clinical manifestations. Olfactory and gustatory abnormalities (anosmia and...
Life, Vol. 10, Pages 157: Histone Deacetylase 1 and Sirtuin 1 Expression in Psoriatic Skin: A Comparison between Guttate and Plaque Psoriasis Life doi: 10.3390/life10090157 Authors: Young-Ji Hwang Jung-Im Na Sang-Young Byun Soon-Hyo Kwon Seung-Hye Yang Hyun-Sun Lee Hye-Ryung Choi Soyun Cho Sang Woong Youn Kyoung-Chan Park Abnormal histone modification by histone deacetylases (HDACs), including HDAC1 and sirtuin 1 (SIRT1), has been reported to play an important...
Life, Vol. 10, Pages 156: Functional Mammalian Amyloids and Amyloid-Like Proteins Life doi: 10.3390/life10090156 Authors: Maria S. Rubel Sergey A. Fedotov Anastasia V. Grizel Julia V. Sopova Oksana A. Malikova Yury O. Chernoff Aleksandr A. Rubel Amyloids are highly ordered fibrous cross-β protein aggregates that are notorious primarily because of association with a variety of incurable human and animal diseases (termed amyloidoses), including Alzheimer’s...
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Medicina, Vol. 56, Pages 425: Dermatological Manifestations in Pediatric Inflammatory Bowel Disease Medicina doi: 10.3390/medicina56090425 Authors: Diaconescu Strat Balan Anton Stefanescu Ioniuc Stanescu Background and Objectives: Over the last years, inflammatory bowel disease (IBD) has been reported on a high incidence in pediatric populations and has been associated with numerous extraintestinal manifestations, making its management a real challenge for the...
Medicina, Vol. 56, Pages 424: Is it Safe for Patients with Left Ventricular Assist Devices to Undergo Non-Cardiac Surgery? Medicina doi: 10.3390/medicina56090424 Authors: Rafal Berger Attila Nemeth Christoph Salewski Rodrigo Sandoval Boburg Metesh Acharya Alexander Weymann Konstantin Zhigalov Bastian Schmack Michel Pompeu B. O. Sá Christian Schlensak Aron-Frederik Popov Background and Objectives: Since the first use of ventricular assist devices (VADs) as...
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Membranes, Vol. 10, Pages 196: Effects of Solids Retention Time on the Anaerobic Membrane Bioreactor with Yttria-Based Ceramic Membrane Treating Domestic Wastewater at Ambient Temperature Membranes doi: 10.3390/membranes10090196 Authors: Rathmalgodage Thejani Nilusha Dawei Yu Junya Zhang Yuansong Wei The effects of solid retention times (SRTs) (100 days, 50 days, 25 days) on the performance, microbial community, and membrane fouling of a lab-scale anaerobic yttria-based ceramic...
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Metabolites, Vol. 10, Pages 339: Lipid Players of Cellular Senescence Metabolites doi: 10.3390/metabo10090339 Authors: Alec Millner G. Ekin Atilla-Gokcumen Lipids are emerging as key players of senescence. Here, we review the exciting new findings on the diverse roles of lipids in cellular senescence, most of which are enabled by the advancements in omics approaches. Senescence is a cellular process in which the cell undergoes growth arrest while retaining metabolic activity. At the...
Metabolites, Vol. 10, Pages 340: Hyperoxic Exposure Caused Lung Lipid Compositional Changes in Neonatal Mice Metabolites doi: 10.3390/metabo10090340 Authors: Abigail L. Peterson Jennifer F. Carr Xiangming Ji Phyllis A. Dennery Hongwei Yao Treatments with supplemental oxygen in premature infants can impair lung development, leading to bronchopulmonary dysplasia (BPD). Although a stage-specific alteration of lung lipidome occurs during postnatal lung development, whether neonatal...
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