Related Articles Ethanol-Induced Oxidative Stress Modifies Inflammation and Angiogenesis Biomarkers in Retinal Pigment Epithelial Cells (ARPE-19): Role of CYP2E1 and its Inhibition by Antioxidants. Antioxidants (Basel). 2020 Aug 21;9(9): Authors: Martinez-Gil N, Vidal-Gil L, Flores-Bellver M, Maisto R, Sancho-Pelluz J, Diaz-Llopis M, M Barcia J, Romero FJ Abstract The retinal pigment epithelium (RPE) plays a key role in retinal health, being...
Sun Aug 23, 2020 16:25
Related Articles A zsírdús étrend indukálta steatosis és a bél-máj tengely változásai. Orv Hetil. 2020 Aug;161(35):1456-1465 Authors: Blázovics A, Sipos P, Kocsis I, Fébel H, Kleiner D, Szentmihályi K, Fehér E Abstract INTRODUCTION: Fatty liver can develop as a result of diseases, surgical procedures, medicaments, malnutrition or excessive alcohol consumption, however, fat and poor fiber feeding can be attributed as the primary cause. Non-alcoholic...
Sat Aug 22, 2020 16:41
Related Articles A májbetegségek kialakulásának új szempontjai - különös tekintettel az autophagiára és a mikro-RNS szerepére. Orv Hetil. 2020 Aug;161(35):1449-1455 Authors: Werling K Abstract Autophagy plays an important role in the homeostasis of the cells and it may be upregulated in response to several types of stresses. Deregulation of autophagy is a key mechanism in the pathogenesis and progression of several liver diseases. Deficient...
Sat Aug 22, 2020 16:41
Related Articles Transcriptional, metabolic, physiological and developmental responses of switchgrass to phosphorus limitation. Plant Cell Environ. 2020 Aug 21;: Authors: Ding N, Huertas R, Torres-Jerez, Ivone, Liu W, Watson B, Scheible WR, Udvardi M Abstract Knowing how switchgrass (Panicum virgatum L.) responds and adapts to phosphorus (P)-limitation will aid efforts to optimize P acquisition and use in this species for sustainable biomass...
Sat Aug 22, 2020 16:41
Related Articles Development and characterization of acidic-pH-tolerant mutants of Zymomonas mobilis through adaptation and next-generation sequencing-based genome resequencing and RNA-Seq. Biotechnol Biofuels. 2020;13:144 Authors: Yang Q, Yang Y, Tang Y, Wang X, Chen Y, Shen W, Zhan Y, Gao J, Wu B, He M, Chen S, Yang S Abstract Background: Acid pretreatment is a common strategy used to break down the hemicellulose component of the lignocellulosic...
Sat Aug 22, 2020 00:51
16 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Aug 23, 2020 16:32
43 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/22PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 22, 2020 16:49
32 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/21PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 22, 2020 01:01
33 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Aug 23, 2020 17:42
33 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Aug 23, 2020 13:40
166 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/22PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 22, 2020 17:37
166 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/22PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 22, 2020 13:36
117 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/21PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Aug 21, 2020 21:34
1658 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Aug 23, 2020 16:41
2390 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/22PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 22, 2020 16:35
3336 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/21PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 22, 2020 00:31
Welcome to the chop shop. (Dan Gold via Unsplash/)Home chefs know that complicated recipes that involve chopping and dicing can take a great deal of time. Large and expensive food processors can be cumbersome and sometimes too powerful to handle delicate jobs.Luckily we found some gadgets designed to assist your chopping needs. With devices designed to handle a few key tasks, or devices that can offer a variety of chopping jobs—we’ve got options for you to consider. Now there truly is no excuse not...
05:04
Everything in its rightful place. (Jason Briscoe via Unsplash/)Traditional shelf cabinets are not designed with efficiency in mind. It’s hard to organize food products of all different shapes and sizes, and nearly impossible to see what you have in the back. This inherently creates mess and waste—where your back stored items are left unnoticed and maybe even spoiling. When planning meals it’s not easy to even know if you already have the food you need.No matter your specific needs, every home chef...
05:01
No, not this kind of tree! (Jessica Lewis via Unsplash/)Every cat owner knows just how picky their pet can be about lounging spots—ignoring toys or abandoning a nice, cushy bed because they prefer the box the bed was delivered in. Likewise, cat owners can commiserate over cats scratching at furniture or climbing onto places they shouldn’t be. A cat tree is a great way to give your kitty a safe place to satisfy those urges.We’ve chosen our favorite cat trees.Hours of play. (Amazon/)This cat tree has...
04:50
Traveling alone gives you the opportunity to be completely responsible for yourself, revealing how capable you truly are. Santa Marta, Colombia. (Janelle Kaz/)This story originally featured on Motorcyclist.There’s a lot of trepidation before setting out for the open road, leaving behind comfort and the known. This uncertainty can come from heading to a place you’ve never been before, perhaps away from civilization, out of cell service range, or from embarking on a solo journey—especially if you’re...
01:00
Thunderstorms with lots of lightning and little rain have sparked the worst of the fires. (Unsplash/)Thousands of lightning strikes across California have caused hundreds of individual fires in recent days, creating two massive blazes that mark the second and third largest in the state’s history. Officials expect more “dry lightning”—thunderstorms that don’t produce enough rain to keep the parched land below from sparking—to hit Northern California on Sunday and Monday.More footage from the firefight...
Sun Aug 23, 2020 18:50
Take a seat, it's time to learn about toilets. (Giorgio Trovato/Unsplash/)Your toilet is always there for you. It waits in the same spot every day, ready to receive your gracious gastrointestinal gifts with open arms. But have you really gotten to know your porcelain partner beyond its beautiful (if sometimes cold) exterior?If you haven’t, you could be in for some heartbreak when things start to go wrong: running water, a flush handle that doesn’t work, even “ghost” flushes. Rather than scheduling...
Sun Aug 23, 2020 16:00
From top left, clockwise: The Revolution Core 32, OneWheel Pint, Penny Australia, Arbor Fish Groundswell, and Alien Workshop board. (Jarren Vink/)Popular Science’s Play issue is now available to everyone. Read it now, no app or credit card required.Whether you want to bust tricks or just cruise around, there’s a skateboard that’ll get you moving. These half-dozen options are perfect for different kinds of rides.For indoorsThe Revolution Core 32 helps hone your balancing skills. Perching on the...
Sun Aug 23, 2020 00:00
Destiny 2 typically doesn't run on a Chromebook. (Steam/)Chromebooks are in a spotlight right now. With schools about to re-open with large contingents of remote students, these mostly cheap, typically tiny, Google-powered machines are currently selling at roughly four times their typical rate. While Chromebooks are a solid choice for productivity and web browsing, gaming options are mostly limited to Android apps meant for tablets and phones, or Google’s own Stadia cloud gaming service. But this...
Sat Aug 22, 2020 12:00
What do Bugs Bunny and athletic trainers have in common? (Muti/)Popular Science’s Play issue is now available to everyone. Read it now, no app or credit card required. In the 1996 film Space Jam, Bugs Bunny supplies his demoralized Looney Tunes teammates with Michael Jordan’s “Secret Stuff,” which delivers the boost they need to win the game. But unbeknownst to Daffy and the gang, it’s just water.The scene depicts the placebo effect, in which faith in a treatment can be as effective as the real thing....
Fri Aug 21, 2020 23:00
As of 2020, all new homes in California are required to have rooftop solar panels, which should be a boon to the sapped energy grid. (Pexels/)Jeremy Deaton writes for Nexus Media, a nonprofit climate change news service. You can follow him @deaton_jeremy. This story was published in partnership with Nexus Media.Record heat out West last weekend spurred Californians to blast their air conditioners, stretching the power grid so thin that the state started rationing electricity. For the first time since...
Fri Aug 21, 2020 21:00
We thought we'd show you things from the dishes' point of view. (Wendelin Jacober/Pexels/)Loading the dishwasher is a remarkably controversial activity. After five years of marriage, my wife and I still debate the proper method for getting dishes clean with minimal hassle. So I spoke to an expert to settle our battle once and for all.“It’s a contentious issue in most households,” says Richard Tarrant, who’s in charge of marketing Bosch’s dish care products. “We do a lot of consumer studies to gain...
Fri Aug 21, 2020 19:07
For the past 118 years, census takers have traveled on foot, horse, snowmobile, and more to capture basic demographic data from Americans. This is the first year that the survey can be filled out online. (US Census Bureau/)A national census only comes around once every decade, but this year’s has truly been special.When the 2020 US census launched back in March, it was the first survey of its kind that could be filled out online. Typically, the federal government mails paper ballots to each household...
Fri Aug 21, 2020 17:45
New Zealand, where the fossilized leaves were found (Tyler Lastovich/Pexels/)23 million-year-old mummified leaves might give us a peak at how plants might respond to our changing climate in the distant future. In a study published on August 20 in the journal Climate of the Past, Biologists and geologists examined exceptionally well-preserved fossils from a lakebed in New Zealand and found evidence that they thrived in a time when the amount of carbon dioxide in the atmosphere was higher than it is...
Fri Aug 21, 2020 15:00
Related Articles Correction to: CDSnake: Snakemake pipeline for retrieval of annotated OTUs from paired-end reads using CD-HIT utilities. BMC Bioinformatics. 2020 Aug 19;21(1):362 Authors: Kondratenko Y, Korobeynikov A, Lapidus A Abstract An amendment to this paper has been published and can be accessed via the original article. PMID: 32814545 [PubMed - in process]
Fri Aug 21, 2020 22:43
A randomised controlled trial of feedback to improve patient satisfaction and consultation skills in medical students. BMC Med Educ. 2020 Aug 20;20(1):277 Authors: Lai MMY, Roberts N, Mohebbi M, Martin J Abstract BACKGROUND: The use of feedback has been integral to medical student learning, but rigorous evidence to evaluate its education effect is limited, especially in the role of patient feedback in clinical teaching and practice improvement....
Fri Aug 21, 2020 23:27
Seeking connection: a mixed methods study of mental well-being and community volunteerism among international migrants in Japan. BMC Public Health. 2020 Aug 20;20(1):1272 Authors: Miller R, Ong KIC, Choi S, Shibanuma A, Jimba M Abstract BACKGROUND: International migration is a stressful process for which non-Western nations are a growing destination. However, little attention has been paid to the psychological well-being of international residents...
Sat Aug 22, 2020 00:52
Intellectual disability, exercise and aging: the IDEA study: study protocol for a randomized controlled trial. BMC Public Health. 2020 Aug 20;20(1):1266 Authors: Oviedo GR, Javierre C, Font-Farré M, Tamulevicius N, Carbó-Carreté M, Figueroa A, Pérez-Testor S, Cabedo-Sanromá J, Moss SJ, Massó-Ortigosa N, Guerra-Balic M Abstract BACKGROUND: People with intellectual disabilities (ID) have low levels of physical activity (PA) together with accelerated...
Sat Aug 22, 2020 00:52
Onset and remission of common mental disorders among adults living in temporary housing for three years after the triple disaster in Northeast Japan: comparisons with the general population. BMC Public Health. 2020 Aug 20;20(1):1271 Authors: Kawakami N, Fukasawa M, Sakata K, Suzuki R, Tomita H, Nemoto H, Yasumura S, Yabe H, Horikoshi N, Umeda M, Suzuki Y, Shimoda H, Tachimori H, Takeshima T, Bromet EJ Abstract BACKGROUND: People living in temporary...
Sat Aug 22, 2020 00:52
The high prevalence of intestinal parasitic infections is associated with stunting among children aged 6-59 months in Boricha Woreda, Southern Ethiopia: a cross-sectional study. BMC Public Health. 2020 Aug 20;20(1):1270 Authors: Yoseph A, Beyene H Abstract BACKGROUND: Prior studies reported controversial results about the association between intestinal parasitic infections and childhood under-nutrition. We investigated the association of intestinal...
Sat Aug 22, 2020 00:52
Mortality analysis of burns in a developing country: a CAMEROONIAN experience. BMC Public Health. 2020 Aug 20;20(1):1269 Authors: Forbinake NA, Ohandza CS, Fai KN, Agbor VN, Asonglefac BK, Aroke D, Beyiha G Abstract BACKGROUND: Burns are a serious public health problem worldwide accounting for an estimated 265,000 deaths annually from fires alone. The vast majority (96%) of deaths from fire-related burns occur in low- and middle-income countries...
Sat Aug 22, 2020 00:52
Preadolescents' healthy eating behavior: peeping through the social norms approach. BMC Public Health. 2020 Aug 20;20(1):1268 Authors: Ragelienė T, Grønhøj A Abstract BACKGROUND: The rising childhood obesity rate is a major public health challenge. The objective of this study is to examine key underlying mechanisms for peer-related social influence on preadolescents' healthy eating behavior by including factors closely linked with the quality...
Sat Aug 22, 2020 00:52
Acceptability of pre-exposure prophylaxis for HIV prevention: facilitators, barriers and impact on sexual risk behaviors among men who have sex with men in Benin. BMC Public Health. 2020 Aug 20;20(1):1267 Authors: Ahouada C, Diabaté S, Mondor M, Hessou S, Guédou FA, Béhanzin L, Batona G, Gning NN, Zannou DM, Alary M Abstract BACKGROUND: In Benin, men who have sex with men (MSM) do not always use condoms during anal sex. Pre-exposure prophylaxis...
Sat Aug 22, 2020 00:52
Physical environmental and occupational factors inducing work-related neck and shoulder pains among self-employed tailors of informal sectors in Ethiopia, 2019: results from a community based cross-sectional study. BMC Public Health. 2020 Aug 20;20(1):1265 Authors: Mekonnen TH, Yenealem DG, Geberu DM Abstract BACKGROUND: Musculoskeletal disorders (MSD) caused by occupational-related factors continue to place huge burdens on global workforces....
Sat Aug 22, 2020 00:52
Does family communication moderate the association between adverse childhood experiences and emotional and behavioural problems? BMC Public Health. 2020 Aug 20;20(1):1264 Authors: Lackova Rebicova M, Dankulincova Veselska Z, Husarova D, Klein D, Madarasova Geckova A, van Dijk JP, Reijneveld SA Abstract BACKGROUND: Adverse childhood experiences (ACEs) and poor family support and communication can increase emotional and behavioural problems (EBP)....
Sat Aug 22, 2020 00:52
Superdiversity, migration and use of internet-based health information - results of a cross-sectional survey conducted in 4 European countries. BMC Public Health. 2020 Aug 20;20(1):1263 Authors: Samkange-Zeeb F, Borisova L, Padilla B, Bradby H, Phillimore J, Zeeb H, Brand T Abstract BACKGROUND: Studies of factors associated with the use of Internet-based health information generally focus on general, rather than migrant populations. This study...
Sat Aug 22, 2020 00:52
Related Articles Income and wealth as determinants of voluntary private health insurance: empirical evidence in Spain, 2008-2014. BMC Public Health. 2020 Aug 19;20(1):1262 Authors: Pinilla J, López-Valcárcel BG Abstract BACKGROUND: Few studies have quantitatively estimated the income elasticity of demand of voluntary private health insurance (VPHI) in countries with a universal National Health Service. Most studies to date have uses cross-sectional...
Sat Aug 22, 2020 00:52
63 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2020/08/21PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Aug 22, 2020 01:13
Related Articles The Effect of a Paired Lab on Course Completion and Grades in Nonmajors Introductory Biology. CBE Life Sci Educ. 2020 Sep;19(3):ar36 Authors: DeFeo DJ, Bibler A, Gerken S Abstract This paper explores the effect of a paired lab course on students' course outcomes in nonmajors introductory biology at the University of Alaska Anchorage. We compare course completion and final grades for 10,793 students (3736 who simultaneously enrolled...
Sat Aug 22, 2020 16:25
Related Articles Applying Experiential Learning to Career Development Training for Biomedical Graduate Students and Postdocs: Perspectives on Program Development and Design. CBE Life Sci Educ. 2020 Sep;19(3):es7 Authors: Van Wart A, O'Brien TC, Varvayanis S, Alder J, Greenier J, Layton RL, Stayart CA, Wefes I, Brady AE Abstract Experiential learning is an effective educational tool across many academic disciplines, including career development....
Sat Aug 22, 2020 16:25
Related Articles Students' Understanding of the Dynamic Nature of Genetics: Characterizing Undergraduates' Explanations for Interaction between Genetics and Environment. CBE Life Sci Educ. 2020 Sep;19(3):ar37 Authors: Haskel-Ittah M, Duncan RG, Yarden A Abstract The idea of the interaction between genes and environment in the formation of traits is an important component of genetic literacy, because it explains the plastic nature of phenotypes....
Sat Aug 22, 2020 16:25
Related Articles Water, water everywhere! Any to drink? Conserv Physiol. 2020;8(1):coaa071 Authors: Schwieterman G PMID: 32821393 [PubMed - as supplied by publisher]
Sat Aug 22, 2020 14:06
Performance and Feasibility of Recalls Completed Using the Automated Self-Administered 24-Hour Dietary Assessment Tool in Relation to Other Self-Report Tools and Biomarkers in the Interactive Diet and Activity Tracking in AARP (IDATA) Study. J Acad Nutr Diet. 2020 Aug 17;: Authors: Subar AF, Potischman N, Dodd KW, Thompson FE, Baer DJ, Schoeller DA, Midthune D, Kipnis V, Kirkpatrick SI, Mittl B, Zimmerman TP, Douglass D, Bowles HR, Park Y Abstract ...
Fri Aug 21, 2020 23:50
Unfolding cytochromes c-b562 and Rd apo b562. J Inorg Biochem. 2020 Aug 10;211:111209 Authors: Kozak JJ, Gray HB, Garza-López RA Abstract We have analyzed the early stages of unfolding of cytochromes c-b562 (PDB ID: 2BC5) and Rd apo b562 (PDB ID: 1YYJ). Our geometrical approach proceeds from an analysis of the crystal structure reported for each protein. We quantify, residue-by-residue and region-by-region, the spatial and angular changes in...
Sat Aug 22, 2020 01:13
Fabrication of PNIPAM-chitosan/decatungstoeuropate/silica nanocomposite for thermo/pH dual-stimuli-responsive and luminescent drug delivery system. J Inorg Biochem. 2020 Aug 10;211:111216 Authors: Huang N, Wang J, Cheng X, Xu Y, Li W Abstract A luminescent and dual-stimuli-responsive nanocomposite based on mesoporous silica, poly (N-isopropylacrylamide)-chitosan and decatungstoeuropate was prepared. To fabricate the nanocomposite, the mesoporous...
Sat Aug 22, 2020 01:13
Related Articles Influence of age on the frequency characteristics of the soleus muscle response to Achilles tendon vibration during standing. J Physiol. 2020 Aug 21;: Authors: Mildren RL, Schmidt ME, Eschelmuller G, Carpenter MG, Blouin JS, Inglis JT Abstract KEY POINTS: Proprioceptive sensory information from the ankle joint is critical for the control of upright posture and balance We examined the influence of age (n = 54 healthy adults,...
Sat Aug 22, 2020 13:38
Related Articles Preventative therapeutic approaches for hypertrophic cardiomyopathy. J Physiol. 2020 Aug 21;: Authors: Solomon T, Filipovska A, Hool L, Viola H Abstract Sarcomeric gene mutations are associated with the development of hypertrophic cardiomyopathy (HCM). Current drug therapeutics for HCM patients are effective in relieving symptoms, but do not prevent or reverse disease progression. Moreover, due to heterogeneity in the clinical...
Sat Aug 22, 2020 13:38
Related Articles Oxidative stress in the medullary respiratory neurons contributes to the respiratory dysfunction in the 6-OHDA model of Parkinson's disease. J Physiol. 2020 Aug 21;: Authors: Falquetto B, Thieme K, Malta MB, E Rocha KC, Tuppy M, Potje SR, Antoniali C, Rodrigues AC, Munhoz CD, Moreira TS, Takakura AC Abstract KEY POINTS: Parkinson's disease (PD) is associated with respiratory dysfunction. The 6-OHDA rat model exhibited a reduction...
Sat Aug 22, 2020 13:38
Related Articles Loss of variable fascicle gearing during voluntary isometric contractions of paretic medial gastrocnemius muscles in male chronic stroke survivors. J Physiol. 2020 Aug 20;: Authors: Son J, Rymer WZ Abstract KEY POINTS: Maximum fascicle shortening/rotation was significantly decreased in paretic medial gastrocnemius (MG) muscles compared to non-paretic MG muscles. Fascicle gear ratio on both sides decreased as the ankle became...
Fri Aug 21, 2020 21:33
Related Articles Myosin dynamics during relaxation in mouse soleus muscle and modulation by 2'-deoxy-ATP. J Physiol. 2020 Aug 20;: Authors: Ma W, Childers M, Murray J, Moussavi-Harami F, Gong H, Weiss R, Daggett V, Irving T, Regnier M Abstract KEY POINTS: Skeletal muscle relaxation has been primarily studied by assessing the kinetics of force decay. Little is known about the resultant dynamics of structural changes in myosin heads during relaxation....
Fri Aug 21, 2020 21:33
Related Articles Lift, stop, rest, repeat: The potential of 'cluster sets' as interval resistance exercise for COPD. J Physiol. 2020 Aug 20;: Authors: Latella C PMID: 32818291 [PubMed - as supplied by publisher]
Fri Aug 21, 2020 21:33
Related Articles Autophagy machinery promotes the chaperone-mediated formation and compartmentalization of protein aggregates during appressorium development by the rice blast fungus. Mol Biol Cell. 2020 Aug 20;:mbcE20010068 Authors: Rogers AM, Egan MJ Abstract The chaperone-mediated sequestration of misfolded proteins into specialized quality control compartments represents an important strategy for maintaining protein homeostasis in response...
Fri Aug 21, 2020 22:36
Related Articles Novel function for AP-1B during cell migration. Mol Biol Cell. 2020 Aug 20;:mbcE20040256 Authors: Kell MJ, Ang SF, Pigati L, Halpern A, Fölsch H Abstract The epithelial cell-specific clathrin adaptor AP-1B has a well-established role in polarized sorting of cargos to the basolateral membrane. Here we show that β1 integrin was dependent on AP-1B and its co-adaptor, autosomal recessive hypercholesterolemia protein (ARH), for sorting...
Fri Aug 21, 2020 22:36
Related Articles The Drosophila melanogaster Rab GAP RN-tre crosstalks with the Rho1 signaling pathway to regulate non-muscle myosin II localization and function. Mol Biol Cell. 2020 Aug 20;:mbcE20030181 Authors: Platenkamp A, Detmar E, Sepulveda L, Ritz A, Rogers SL, Applewhite DA Abstract To identify novel regulators of non-muscle myosin II (NMII) we performed an image-based RNAi screen using stable Drosophila melanogaster S2 cells expressing...
Fri Aug 21, 2020 22:36
Related Articles Lamin A/C Deficiency Enables Increased Myosin2 Bipolar Filament Ensembles Which Promote Divergent Actomyosin Network Anomalies Through Self Organization. Mol Biol Cell. 2020 Aug 20;:mbcE20010017T Authors: Wiggan O, DeLuca JG, Stasevich TJ, Bamburg JR Abstract Nuclear envelope proteins influence cell cytoarchitecure by poorly understood mechanisms. Here we show that siRNA-mediated silencing of lamin A/C (LMNA) promotes contrasting...
Fri Aug 21, 2020 22:36
Related Articles Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates. Proc Natl Acad Sci U S A. 2020 Aug 21;: Authors: Damas J, Hughes GM, Keough KC, Painter CA, Persky NS, Corbo M, Hiller M, Koepfli KP, Pfenning AR, Zhao H, Genereux DP, Swofford R, Pollard KS, Ryder OA, Nweeia MT, Lindblad-Toh K, Teeling EC, Karlsson EK, Lewin HA Abstract The novel coronavirus severe acute respiratory syndrome...
Sun Aug 23, 2020 14:26
Related Articles LIN28B/let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling. Proc Natl Acad Sci U S A. 2020 Aug 21;: Authors: Li XJ, Doetzlhofer A Abstract Mechano-sensory hair cells within the inner ear cochlea are essential for the detection of sound. In mammals, cochlear hair cells are only produced during development and their loss, due to disease or trauma, is a leading cause...
Sun Aug 23, 2020 14:26
Related Articles Estimating unobserved SARS-CoV-2 infections in the United States. Proc Natl Acad Sci U S A. 2020 Aug 21;: Authors: Perkins TA, Cavany SM, Moore SM, Oidtman RJ, Lerch A, Poterek M Abstract By March 2020, COVID-19 led to thousands of deaths and disrupted economic activity worldwide. As a result of narrow case definitions and limited capacity for testing, the number of unobserved severe acute respiratory syndrome coronavirus 2...
Sun Aug 23, 2020 14:26
Related Articles IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome. Proc Natl Acad Sci U S A. 2020 Aug 21;: Authors: Kang S, Tanaka T, Inoue H, Ono C, Hashimoto S, Kioi Y, Matsumoto H, Matsuura H, Matsubara T, Shimizu K, Ogura H, Matsuura Y, Kishimoto T Abstract Cytokine release syndrome (CRS) is a life-threatening complication induced by systemic inflammatory responses...
Sun Aug 23, 2020 14:26
Related Articles The paradoxical lean phenotype of hypothyroid mice is marked by increased adaptive thermogenesis in the skeletal muscle. Proc Natl Acad Sci U S A. 2020 Aug 21;: Authors: Kaspari RR, Reyna-Neyra A, Jung L, Torres-Manzo AP, Hirabara SM, Carrasco N Abstract Obesity is a major health problem worldwide, given its growing incidence and its association with a variety of comorbidities. Weight gain results from an increase in energy...
Sun Aug 23, 2020 14:26
Related Articles Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription. Proc Natl Acad Sci U S A. 2020 Aug 21;: Authors: Sengupta S, Wang H, Yang C, Szczesny B, Hegde ML, Mitra S Abstract Among several reversible epigenetic changes occurring during transcriptional activation, only demethylation of histones and cytosine-phosphate-guanines (CpGs) in gene promoters and other regulatory...
Sun Aug 23, 2020 14:26
122 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/08/21PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Aug 21, 2020 21:58
Οι επικεφαλής των ιατρικών υπηρεσιών του Ηνωμένου Βασιλείου δηλώνουν ότι τα παιδιά πρέπει να επιστρέψουν στο σχολείο μετά τις καλοκαιρινές διακοπές, προειδοποιώντας ότι το να χάσουν το σχολείο δημιουργεί πολύ μεγαλύτερους κινδύνους γι’αυτά από το να προσβληθούν από νέο κορωνοϊό. Η σπάνια αυτή κοινή ανακοίνωση από τους ανώτατους συμβούλους για θέματα υγείας των κυβερνήσεων της Αγγλίας, της Σκωτίας, της Ουαλίας και της Βόρειας Ιρλανδίας ενισχύει τον πρωθυπουργό Μπόρις Τζόνσον, ο οποίος έχει πει ότι...
Sun Aug 23, 2020 14:52
Έρευνα που αφορά πρωτίστως τον εντοπισμό χαρακτηριστικών στο γονιδίωμα ασθενών που έχουν μολυνθεί με τον ιό Sars-Cov-2 και την αναζήτηση βιοδεικτών που μπορούν να συμβάλλουν στην αποτελεσματική θεραπευτική αγωγή, θα αποτελέσει το αντικείμενο της συνεργασίας που αρχίζει μεταξύ των ερευνητικών εργαστηρίων της Πνευμονολογικής Κλινικής του ΑΠΘ του νοσοκομείου «Γεώργιος Παπανικολάου» (Ερευνητικό Εργαστήριο Ανοσολογίας και Αλλεργικών Παθήσεων του Αναπνευστικού) και του Τμήματος Πειραματικής Ιατρικής του...
Sat Aug 22, 2020 18:57
Είναι δυνατόν να επιτραπούν και πάλι οι ποπ συναυλίες παρά την Covid-19; Το γερμανικό πανεπιστήμιο του Χάλε άρχισε σήμερα ένα γιγάντιο πείραμα με 4.000 συμμετέχοντες για να επιχειρήσει να δώσει μια απάντηση στην ερώτηση αυτή. Ένας διάσημος στη Γερμανία τραγουδιστής της ποπ, ο Τιμ Μπέντζκο, δέχθηκε να συμμετάσχει σ’ αυτό το τεστ δίνοντας μέσα στην ίδια ημέρα στη Λειψία τρεις συναυλίες με διαφορετικά μέτρα στην καθεμιά, ώστε να δοθεί η δυνατότητα στους ερευνητές να προσδιορίσουν ποια είναι η καλύτερη...
Sat Aug 22, 2020 14:02
Τα ταχυφαγεία και τα εστιατόρια πρόχειρου φαγητού μπορεί να έχουν συνδεθεί με κακή υγεία, φαίνεται όμως πως για μια ομάδα του πληθυσμού οι συχνές επισκέψεις σε τέτοια μέρη εστίασης έχουν ένα σημαντικό όφελος. Οι παραπάνω χώροι εστίασης όπως και τα καφέ, ισχυρίζεται νέα μελέτη από το Πανεπιστήμιο του Μίσιγκαν, μπορούν να δράσουν προστατευτικά για την γνωστική ικανότητα των ηλικιωμένων, με τρόπο παρόμοιο του γάμου. Τα ενδιαφέροντα ευρήματα δημοσιεύονται στο Health and Place. Για τις ανάγκες της μελέτης,...
Fri Aug 21, 2020 14:32
Μια ομάδα ερευνητών από το Ινστιτούτο Karolinska και το Πανεπιστήμιο της Στοκχόλμης βρήκε μια σύνδεση ανάμεσα στο πόση υπνηλία νιώθουν οι άνθρωποι κατά τη διάρκεια της ημέρας και στον βαθμό κοινωνικοποίησής τους. Στη σχετική δημοσίευση στο Proceedings of the National Academy of Sciences, οι επιστήμονες περιγράφουν τη μελέτη ύπνου και μοτίβων κοινωνικοποίησης σε μια ομάδα εθελοντών, αλλά και τα συμπεράσματά τους. Ανεπίσημα μέχρι σήμερα στοιχεία υποδείκνυαν ότι όταν οι άνθρωποι αισθάνονται κούραση...
Fri Aug 21, 2020 14:00
Οι διαταραχές της αρτηριακής πίεσης κατά την εγκυμοσύνη έχουν συσχετιστεί με αυξημένο κίνδυνο χρόνιας υπέρτασης, διαβήτη, στεφανιαίας νόσου, εγκεφαλικού επεισοδίου και πρόωρου θανάτου από καρδιαγγειακό νόσημα. Μία νέα μελέτη της Εταιρείας Εμμηνόπαυσης Βορείου Αμερικής (NAMS) έρχεται τώρα να διαπιστώσει πως ενδέχεται να είναι εξίσου αυξημένος ο κίνδυνος για την εκδήλωση πιο σοβαρών ή ενοχλητικών συμπτωμάτων κατά την εμμηνόπαυση, συμπεριλαμβανομένων των εξάψεων. Οι διαταραχές της αρτηριακής πίεσης...
Fri Aug 21, 2020 13:38
Η χρήση αντιβιοτικών, και ειδικά εκείνων με μεγαλύτερο φάσμα μικροβιακής κάλυψης, ενδέχεται να σχετίζεται με αυξημένο κίνδυνο εμφάνισης φλεγμονώδους νοσήματος του εντέρου, σύμφωνα με μία μελέτη ερευνητών από το Ινστιτούτο Karolinska της Σουηδίας και την Ιατρική Σχολή του Χάρβαρντ που δημοσιεύθηκε στο The Lancet Gastroenterology & Hepatology. Στην πιο μεγάλη μέχρι σήμερα μελέτη που συνδέει την αντιβιοτική θεραπεία με τον κίνδυνο φλεγμονώδους νοσήματος του εντέρου, οι ερευνητές κατάφεραν να δείξουν...
Fri Aug 21, 2020 13:25
Στη νέα μελέτη ερευνητών από Πανεπιστήμιο Rutgers που δημοσιεύθηκε στο Immunity, ο επικεφαλής συγγραφέας και αναπληρωτής καθηγητής κυτταρικής βιολογίας, Nan Gao, αναφέρει ότι το εντερικό ένζυμο λυσοζύμη, το οποίο φυσιολογικά λειτουργεί για να περιορίζει την ανάπτυξη των βακτηρίων, στους ανθρώπους με ελκώδη κολίτιδα λειτουργεί αντίθετα ενεργοποιώντας τη φλεγμονή. Η διαδικασία αυτή έχει ως αποτέλεσμα των σχηματισμό ελκών και πληγών στο παχύ έντερο και το ορθό, χαρακτηριστικά γνωρίσματα των φλεγμονωδών...
Fri Aug 21, 2020 08:51
Την καίρια σημασία της διατήρησης ενός υγιούς σωματικού βάρους σε όλα τα ηλικιακά στάδια καταδεικνύει μεγάλης κλίμακας μελέτη παρατήρησης της Ιατρικής Σχολής του Πανεπιστημίου της Βοστόνης, η οποία διαπιστώνει ότι οι εναλλαγές στο βάρος από την εφηβεία έως τη μέση ηλικία έχουν σημαντική επίδραση στον κίνδυνο πρόωρου θανάτου. Στα ευρήματα της μελέτης -η οποία δημοσιεύτηκε στο JAMA Network Open– αναφέρεται ότι οι συμμετέχοντες που ανήκαν βάσει του δείκτη μάζα σώματος στην κατηγορία του παχύσαρκου...
Fri Aug 21, 2020 08:40
Σε παγκόσμιο επίπεδο υπάρχει προβληματισμός για την πιθανότητα μετάδοσης του νέου κορωνοϊού SARS-CoV-2 κατά τη διάρκεια του μητρικού θηλασμού από τη μητέρα στο βρέφος. Αξίζει να σημειωθεί ότι ορισμένοι φορείς ήδη σημειώνουν ότι οι μητέρες που έχουν νοσήσει από COVID-19 μπορούν να επιλέξουν να θηλάσουν με προστατευτικά μέτρα για να αποτραπεί η μετάδοση του ιού στο νεογνό μέσω αναπνευστικών σταγονιδίων κατά τη διάρκεια του θηλασμού. Οι Ιατροί της Θεραπευτικής Κλινικής της Ιατρικής Σχολής του Εθνικού...
Fri Aug 21, 2020 08:11
Μπορούμε να αποκτήσουμε ανοσία στον SARS-CoV-2, τον ιό που προκαλεί τη νόσο COVID-19, χωρίς ποτέ να εκτεθούμε σε αυτόν; Νέες μελέτες βρήκαν ότι άνθρωποι που δεν είχαν παρουσιάσει ποτέ συμπτώματα, δεν εκτέθηκαν ή δεν βγήκαν θετικοί σε τεστ κορωνοϊού μπορεί να έχουν ανοσοκύτταρα που μπορούν να αναγνωρίσουν και ενδεχομένως να σκοτώσουν τα κύτταρα που έχουν προσβληθεί από τον ιό. Πολλά κρυολογήματα προκαλούνται από κορωνοϊούς Οι κορωνοϊοί που μπορούν να μολύνουν τους ανθρώπους είναι επτά. Οι τρεις...
Fri Aug 21, 2020 07:57
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου