Antibiotics, Vol. 9, Pages 540: Molecular and Phenotypic Characterization of Escherichia coli Associated with Granulomatous Colitis of Boxer Dogs Antibiotics doi: 10.3390/antibiotics9090540 Authors: Belgin Dogan Shiying Zhang Sarah E. Kalla Esra I. Dogan Cindy Guo Chelston R. Ang Kenneth W. Simpson Invasive Escherichia coli is causally associated with granulomatous colitis (GC) of Boxer dogs and French Bulldogs. The virulence determinants of GC E. coli are unclear....
Antibiotics, Vol. 9, Pages 538: Verification of a Novel Approach to Predicting Effects of Antibiotic Combinations: In Vitro Dynamic Model Study with Daptomycin and Gentamicin against Staphylococcus aureus Antibiotics doi: 10.3390/antibiotics9090538 Authors: Maria V. Golikova Elena N. Strukova Yury A. Portnoy Stephen H. Zinner Alexander A. Firsov To explore whether susceptibility testing with antibiotic combinations at pharmacokinetically derived concentration ratios is predictive...
Antibiotics, Vol. 9, Pages 539: Ibrexafungerp: A Novel Oral Triterpenoid Antifungal in Development for the Treatment of Candida auris Infections Antibiotics doi: 10.3390/antibiotics9090539 Authors: Mahmoud Ghannoum Maiken Cavling Arendrup Vishnu P. Chaturvedi Shawn R. Lockhart Thomas S. McCormick Sudha Chaturvedi Elizabeth L. Berkow Deven Juneja Bansidhar Tarai Nkechi Azie David Angulo Thomas J. Walsh Candida auris is an emerging multidrug-resistant fungal...
Antibiotics, Vol. 9, Pages 537: Synthesis of Novel Stilbene–Coumarin Derivatives and Antifungal Screening of Monotes kerstingii-Specialized Metabolites Against Fusarium oxysporum Antibiotics doi: 10.3390/antibiotics9090537 Authors: Ghislain Wabo Fotso Bathelemy Ngameni Thomas E. Storr Bonaventure Tchaleu Ngadjui Sibongile Mafu G. Richard Stephenson Fusarium is one of the most toxigenic phytopathogens causing diseases and reduced agricultural productivity worldwide. Current...
Antibiotics, Vol. 9, Pages 536: Validating Use of Electronic Health Data to Identify Patients with Urinary Tract Infections in Outpatient Settings Antibiotics doi: 10.3390/antibiotics9090536 Authors: George Germanos Patrick Light Roger Zoorob Jason Salemi Fareed Khan Michael Hansen Kalpana Gupta Barbara Trautner Larissa Grigoryan Objective: To validate the use of electronic algorithms based on International Classification of Diseases (ICD)-10 codes to identify...
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Antioxidants, Vol. 9, Pages 788: Cudratricusxanthone O Inhibits H2O2-Induced Cell Damage by Activating Nrf2/HO-1 Pathway in Human Chondrocytes Antioxidants doi: 10.3390/antiox9090788 Authors: Eun-Nam Kim Hyun-Su Lee Gil-Saeng Jeong Osteoarthritis (OA) is a common joint degenerative disease induced by oxidative stress in chondrocytes. Although induced-heme oxygenase-1 (HO-1) has been found to protect cells against oxygen radical damage, little information is available regarding...
Antioxidants, Vol. 9, Pages 786: The Phosphodiesterase Type 5 Inhibitor Sildenafil Improves DNA Stability and Redox Homeostasis in Systemic Sclerosis Fibroblasts Exposed to Reactive Oxygen Species Antioxidants doi: 10.3390/antiox9090786 Authors: Luigi Di Luigi Guglielmo Duranti Ambra Antonioni Paolo Sgrò Roberta Ceci Clara Crescioli Stefania Sabatini Andrea Lenzi Daniela Caporossi Francesco Del Galdo Ivan Dimauro Cristina Antinozzi Systemic sclerosis...
Antioxidants, Vol. 9, Pages 787: Characterization of Novel Synthetic Polyphenols: Validation of Antioxidant and Vasculoprotective Activities Antioxidants doi: 10.3390/antiox9090787 Authors: María Jesús Pérez de Vega Silvia Moreno-Fernández Gloria María Pontes-Quero María González-Amor Blanca Vázquez-Lasa Beatriz Sabater-Muñoz Ana M. Briones María R. Aguilar Marta Miguel Rosario González-Muñiz Antioxidant compounds, including polyphenols, have therapeutic effects...
Antioxidants, Vol. 9, Pages 785: Green Extraction of Antioxidant Polyphenols from Green Tea (Camellia sinensis) Antioxidants doi: 10.3390/antiox9090785 Authors: Qiong Luo Jia-Rong Zhang Hua-Bin Li Ding-Tao Wu Fang Geng Harold Corke Xin-Lin Wei Ren-You Gan In this study, the feasibility of improving the extraction yield of green tea antioxidant polyphenols by the combination of ultrasound-assisted extraction (UAE) and deep eutectic solvents (DESs) was investigated....
Antioxidants, Vol. 9, Pages 784: The Importance of Redox Status in the Frame of Lifestyle Approaches and the Genetics of the Lung Innate Immune Molecules, SP-A1 and SP-A2, on Differential Outcomes of COVID-19 Infection Antioxidants doi: 10.3390/antiox9090784 Authors: Fotios Tekos Zoi Skaperda Nikolaos Goutzourelas David S. Phelps Joanna Floros Demetrios Kouretas The pandemic of COVID-19 is of great concern to the scientific community. This mainly affects the elderly and...
Antioxidants, Vol. 9, Pages 783: Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2–KEAP1–CUL3 Interactions in Chronic Kidney Disease Antioxidants doi: 10.3390/antiox9090783 Authors: Bowen Sun Xifan Wang Xiaoxue Liu Longjiao Wang Fazheng Ren Xiaoyu Wang Xiaojing Leng Chronic kidney disease (CKD) is characterized by the accumulation of protein-bound uremic toxins (PBUTs), which play a pathophysiological role in renal fibrosis...
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Atmosphere, Vol. 11, Pages 902: Coproducing Weather Forecast Information with and for Smallholder Farmers in Ghana: Evaluation and Design Principles Atmosphere doi: 10.3390/atmos11090902 Authors: Gbangou Sarku Slobbe Ludwig Kranjac-Berisavljevic Paparrizos Many West African farmers are struggling to cope with changing weather and climatic conditions. This situation limits farmers’ ability to make optimal decisions for food and income security. Developing...
Atmosphere, Vol. 11, Pages 901: Spatial-Temporal Assessment of Satellite-Based Rainfall Estimates in Different Precipitation Regimes in Water-Scarce and Data-Sparse Regions Atmosphere doi: 10.3390/atmos11090901 Authors: Alaba Boluwade Accurate precipitation measurement is very important for socio-hydrological resilience in the face of frequent extreme weather events such as cyclones. This study evaluates the performance of two satellite products: the Tropical Rainfall Measuring Mission...
Atmosphere, Vol. 11, Pages 900: Spatio-Temporal Variations of Atmospheric NH3 over East Asia by Comparison of Chemical Transport Model Results, Satellite Retrievals and Surface Observations Atmosphere doi: 10.3390/atmos11090900 Authors: Zhe Wang Itsushi Uno Kazuo Osada Syuichi Itahashi Keiya Yumimoto Xueshun Chen Wenyi Yang Zifa Wang Atmospheric ammonia (NH3) plays an important role in the formation of secondary inorganic aerosols, the neutralization of acid rain,...
Atmosphere, Vol. 11, Pages 899: Flow Regimes and Föhn Types Characterize the Local Climate of Southern Patagonia Atmosphere doi: 10.3390/atmos11090899 Authors: Franziska Temme Jenny V. Turton Thomas Mölg Tobias Sauter The local climate in Southern Patagonia is strongly influenced by the interaction between the topography and persistent westerlies, which can generate föhn events, dry and warm downslope winds. The upstream flow regime influences different föhn...
Atmosphere, Vol. 11, Pages 898: A Review of Climate-Smart Agriculture Applications in Cyprus Atmosphere doi: 10.3390/atmos11090898 Authors: George Adamides Climate-smart agriculture is an approach for developing agricultural strategies to modernize agricultural systems using digital techniques, aiming for sustainable agriculture and ensuring food security under climate change. This article provides a systematic literature review of smart agriculture technologies towards climate-smart...
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Biology, Vol. 9, Pages 248: The Phytochemical, Antifungal, and First Report of the Antiviral Properties of Egyptian Haplophyllum tuberculatum Extract Biology doi: 10.3390/biology9090248 Authors: Ahmed Abdelkhalek Mohamed Z. M. Salem Elsayed Hafez Said I. Behiry Sameer H. Qari In this study, ethanol whole plant extract (WPE) of Haplophyllum tuberculatum was characterized and tested for its antifungal and antiviral activities against Fusarium culmorum, Rhizoctonia solani and...
Biology, Vol. 9, Pages 247: Current Trends in Proteomic Advances for Food Allergen Analysis Biology doi: 10.3390/biology9090247 Authors: María López-Pedrouso José M. Lorenzo Mohammed Gagaoua Daniel Franco Food allergies are a global food challenge. For correct food labelling, the detection and quantification of allergens are necessary. However, novel product formulations and industrial processes produce new scenarios, which require much more technological developments. For this...
Biology, Vol. 9, Pages 246: Histomorphological and Redox Delineations in the Testis and Epididymis of Albino Rats Fed with Green-Synthesized Cellulose Biology doi: 10.3390/biology9090246 Authors: Chiagoziem A. Otuechere Adewale Adewuyi Olusegun L. Adebayo Emmanuel Yawson Omolara Kabiawu Sarah Al-Rashed Blessing Okubio Amany M. Beshbishy Gaber El-Saber Batiha It has also become increasingly necessary to diversify the production of cellulose for biomedical applications....
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Biomedicines, Vol. 8, Pages 307: Integrin-Targeting Peptides for the Design of Functional Cell-Responsive Biomaterials Biomedicines doi: 10.3390/biomedicines8090307 Authors: Junwei Zhao Federica Santino Daria Giacomini Luca Gentilucci Integrins are a family of cell surface receptors crucial to fundamental cellular functions such as adhesion, signaling, and viability, deeply involved in a variety of diseases, including the initiation and progression of cancer, of coronary, inflammatory,...
Biomedicines, Vol. 8, Pages 306: The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection Biomedicines doi: 10.3390/biomedicines8090306 Authors: Francesca Oppedisano Roberta Macrì Micaela Gliozzi Vincenzo Musolino Cristina Carresi Jessica Maiuolo Francesca Bosco Saverio Nucera Maria Caterina Zito Lorenza Guarnieri Federica Scarano Caterina Nicita Anna Rita Coppoletta Stefano Ruga Miriam Scicchitano Rocco...
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Biomolecules, Vol. 10, Pages 1238: Recent Advances in Microbial Production of cis,cis-Muconic Acid Biomolecules doi: 10.3390/biom10091238 Authors: Choi Lee Park Lee Kim : cis,cis-Muconic acid (MA) is a valuable C6 dicarboxylic acid platform chemical that is used as a starting material for the production of various valuable polymers and drugs, including adipic acid and terephthalic acid. As an alternative to traditional chemical processes, bio-based MA production has...
Biomolecules, Vol. 10, Pages 1236: A Fluorescent Assay to Search for Inhibitors of HIV-1 Integrase Interactions with Human Ku70 Protein, and Its Application for Characterization of Oligonucleotide Inhibitors Biomolecules doi: 10.3390/biom10091236 Authors: Simon Galkin Anna Rozina Arthur Zalevsky Marina Gottikh Andrey Anisenko The search for compounds that can inhibit the interaction of certain viral proteins with their cellular partners is a promising trend in the development...
Biomolecules, Vol. 10, Pages 1237: Functional Analysis of P450 Monooxygenase SrrO in the Biosynthesis of Butenolide-type Signaling Molecules in Streptomyces rochei Biomolecules doi: 10.3390/biom10091237 Authors: Aiko Teshima Nozomi Hadae Naoto Tsuda Kenji Arakawa Streptomyces rochei 7434AN4 produces two structurally unrelated polyketide antibiotics lankacidin and lankamycin, and their biosynthesis is tightly controlled by butenolide-type signaling molecules SRB1 and SRB2. SRBs...
Biomolecules, Vol. 10, Pages 1235: Green Synthesis of Antileishmanial and Antifungal Silver Nanoparticles Using Corn Cob Xylan as a Reducing and Stabilizing Agent Biomolecules doi: 10.3390/biom10091235 Authors: Rony Lucas Silva Viana Gabriel Pereira Fidelis Mayara Jane Campos Medeiros Marcelo Antonio Morgano Monique Gabriela Chagas Faustino Alves Luiz Felipe Domingues Passero Daniel Lima Pontes Raquel Cordeiro Theodoro Thales Domingos Arantes Diego Araujo Sabry Guilherme...
Biomolecules, Vol. 10, Pages 1234: Evaluation of the In Vitro Oral Wound Healing Effects of Pomegranate (Punica granatum) Rind Extract and Punicalagin, in Combination with Zn (II) Biomolecules doi: 10.3390/biom10091234 Authors: Vildan Celiksoy Rachael L. Moses Alastair J. Sloan Ryan Moseley Charles M. Heard Pomegranate (Punica granatum) is a well-established folklore medicine, demonstrating benefits in treating numerous conditions partly due to its antimicrobial and anti-inflammatory...
Biomolecules, Vol. 10, Pages 1233: Defining the Protein Seeds of Neurodegeneration using Real-Time Quaking-Induced Conversion Assays Biomolecules doi: 10.3390/biom10091233 Authors: Matteo Manca Allison Kraus Neurodegenerative diseases are characterized by the accumulation of disease-related misfolded proteins. It is now widely understood that the characteristic self-amplifying (i.e., seeding) capacity once only attributed to the prions of transmissible spongiform encephalopathy diseases...
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Brain Sciences, Vol. 10, Pages 588: Parkinson’s Disease-Cognitive Rating Scale for Evaluating Cognitive Impairment in Parkinson’s Disease: A Systematic Review Brain Sciences doi: 10.3390/brainsci10090588 Authors: Elena Cecilia Rosca Mihaela Simu The aim of the present systematic review was to examine the evidence on the accuracy and psychometric properties of the Parkinson’s Disease-Cognitive Rating Scale (PD-CRS) for evaluating the presence of cognitive impairment in patients...
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Cancers, Vol. 12, Pages 2415: Detection of Germline Mutations in a Cohort of 139 Patients with Bilateral Breast Cancer by Multi-Gene Panel Testing: Impact of Pathogenic Variants in Other Genes beyond BRCA1/2 Cancers doi: 10.3390/cancers12092415 Authors: Daniele Fanale Lorena Incorvaia Clarissa Filorizzo Marco Bono Alessia Fiorino Valentina Calò Chiara Brando Lidia Rita Corsini Nadia Barraco Giuseppe Badalamenti Antonio Russo Viviana Bazan Patients with...
Cancers, Vol. 12, Pages 2412: Colorectal Cancer Survival in 50- to 69-Year-Olds after Introducing the Faecal Immunochemical Test Cancers doi: 10.3390/cancers12092412 Authors: María Angeles Gutierrez-Stampa Vanessa Aguilar Cristina Sarasqueta Joaquín Cubiella Isabel Portillo Luis Bujanda Population screening has improved early diagnosis of colorectal cancer (CRC). Nonetheless, most cases are diagnosed in symptomatic patients. Faecal immunochemical testing has been recommended...
Cancers, Vol. 12, Pages 2413: Vitamin D Effects on Cell Differentiation and Stemness in Cancer Cancers doi: 10.3390/cancers12092413 Authors: Asunción Fernández-Barral Pilar Bustamante-Madrid Gemma Ferrer-Mayorga Antonio Barbáchano María Jesús Larriba Alberto Muñoz Vitamin D3 is the precursor of 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), a pleiotropic hormone that is a major regulator of the human genome. 1,25(OH)2D3 modulates the phenotype and physiology of many...
Cancers, Vol. 12, Pages 2414: Front-Line Maintenance Therapy in Advanced Ovarian Cancer—Current Advances and Perspectives Cancers doi: 10.3390/cancers12092414 Authors: Thibaut Reverdy Christophe Sajous Julien Péron Olivier Glehen Naoual Bakrin Witold Gertych Jonathan Lopez Benoit You Gilles Freyer Ovarian tumor is the gynecological cancer associated with the highest mortality. Most diseases are diagnosed at an advanced stage, which impairs the chances of prolonged...
Cancers, Vol. 12, Pages 2411: Indolepropionic Acid, a Metabolite of the Microbiome, Has Cytostatic Properties in Breast Cancer by Activating AHR and PXR Receptors and Inducing Oxidative Stress Cancers doi: 10.3390/cancers12092411 Authors: Zsanett Sári Edit Mikó Tünde Kovács Laura Jankó Tamás Csonka Gréta Lente Éva Sebő Judit Tóth Dezső Tóth Péter Árkosy Anita Boratkó Gyula Ujlaki Miklós Török Ilona Kovács Judit Szabó Borbála Kiss Gábor Méhes...
Cancers, Vol. 12, Pages 2410: A Distinctive microRNA (miRNA) Signature in the Blood of Colorectal Cancer (CRC) Patients at Surgery Cancers doi: 10.3390/cancers12092410 Authors: Jessica Gasparello Chiara Papi Matteo Allegretti Elena Giordani Fabio Carboni Settimio Zazza Edoardo Pescarmona Paolo Romania Patrizio Giacomini Chiara Scapoli Roberto Gambari Alessia Finotti Background: Liquid biopsy (LB) provides an examination of the peripheral blood of cancer...
Cancers, Vol. 12, Pages 2409: Kv10.1 Regulates Microtubule Dynamics during Mitosis Cancers doi: 10.3390/cancers12092409 Authors: Naira Movsisyan Luis A. Pardo Kv10.1 (potassium voltage-gated channel subfamily H member 1, known as EAG1 or Ether-à-go-go 1), is a voltage-gated potassium channel, prevailingly expressed in the central nervous system. The aberrant expression of Kv10.1 is detected in over 70% of all human tumor tissues and correlates with poorer prognosis. In...
Cancers, Vol. 12, Pages 2408: Detection of Ovarian Cancer through Exhaled Breath by Electronic Nose: A Prospective Study Cancers doi: 10.3390/cancers12092408 Authors: Francesco Raspagliesi Giorgio Bogani Simona Benedetti Silvia Grassi Stefano Ferla Susanna Buratti Background: Diagnostic methods for the early identification of ovarian cancer (OC) represent an unmet clinical need, as no reliable diagnostic tools are available. Here, we tested the feasibility of electronic...
Cancers, Vol. 12, Pages 2407: Genetic Susceptibility to Endometrial Cancer: Risk Factors and Clinical Management Cancers doi: 10.3390/cancers12092407 Authors: Thilo Dörk Peter Hillemanns Clemens Tempfer Julius Breu Markus C. Fleisch Endometrial cancer (EC) is the most common cancer affecting the female reproductive organs in higher-income states. Apart from reproductive factors and excess weight, genetic predisposition is increasingly recognized as a major factor in endometrial...
Cancers, Vol. 12, Pages 2406: Back to the Future: Rethinking the Great Potential of lncRNAS for Optimizing Chemotherapeutic Response in Ovarian Cancer Cancers doi: 10.3390/cancers12092406 Authors: Abdelrahman M. Elsayed Paola Amero Salama A. Salama Abdelaziz H. Abdelaziz Gabriel Lopez-Berestein Cristian Rodriguez-Aguayo Ovarian cancer (OC) is one of the most fatal cancers in women worldwide. Currently, platinum- and taxane-based chemotherapy is the mainstay for the treatment...
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Cells, Vol. 9, Pages 1963: Coronaviruses: Is Sialic Acid a Gate to the Eye of Cytokine Storm? From the Entry to the Effects Cells doi: 10.3390/cells9091963 Authors: Przemyslaw Wielgat Karol Rogowski Katarzyna Godlewska Halina Car Coronaviruses (CoVs) are a diverse family of the enveloped human and animal viruses reported as causative agents for respiratory and intestinal infections. The high pathogenic potential of human CoVs, including SARS-CoV, MERS-CoV and SARS-CoV-2, is...
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