Related Articles Integrated genomic analysis using chromosomal microarray, fluorescence in situ hybridization and mate pair analyses: Characterization of a cryptic t(9;22)(p24.1;q11.2)/BCR-JAK2 in myeloid/lymphoid neoplasm with eosinophilia. Cancer Genet. 2020 Aug 07;246-247:44-47 Authors: Snider JS, Znoyko I, Lindsey KG, Morse J, Baughn LB, Hoppman NL, Pitel BA, Pearce KE, Schandl CA, Wolff DJ Abstract The 2016 World Health Organization entity...
Sun Aug 23, 2020 14:52
Related Articles Intramedullary Spinal Cord Metastasis from Primary Lung Neuroendocrine Carcinoma: A Case Report and Operative Video. World Neurosurg. 2020 Aug 19;: Authors: Ginalis EE, Jumah F, Raju B, Nanda A Abstract BACKGROUND: Intramedullary spinal cord metastasis (ISCM) account for a minority of all spinal cord tumors. Rarely, symptoms from ISCM may be the initial presentation of an unknown primary carcinoma. Intramedullary metastasis...
Sun Aug 23, 2020 14:52
Related Articles High-grade Neuroendocrine Carcinomas of the Vulva: A Clinicopathologic Study of 16 Cases. Am J Surg Pathol. 2020 Aug 20;: Authors: Chen PP, Ramalingam P, Alvarado-Cabrero I, Euscher ED, Nagarajan P, Lawson BC, Malpica A Abstract Vulvar high-grade neuroendocrine carcinomas (HGNECs) are rare and primarily thought to represent Merkel cell carcinoma (MCC). We present the clinicopathologic features of 16 such cases, the largest series...
Sun Aug 23, 2020 13:47
Related Articles Inflammation in the neoplasms of the adrenal gland: Is there a prognostic role? An immunohistochemical study. Pathol Res Pract. 2020 Sep;216(9):153070 Authors: Guadagno E, Russo D, Pignatiello S, Del Basso De Caro M Abstract INTRODUCTION: Adrenal gland neoplasms are mostly benign. The differential diagnosis between adrenocortical adenoma and carcinoma relies on nine morphologic parameters (Weiss criteria) that are mostly subjective....
Sun Aug 23, 2020 13:47
Related Articles Investigation of somatostatin receptor profile of neuroendocrine carcinomas of the breast. Pathol Res Pract. 2020 Sep;216(9):153066 Authors: Kontogeorgos G, Thodou E, Choreftaki T Abstract Carcinomas of the breast with neuroendocrine features are rare primary neoplasms positive for neuroendocrine markers. According to the WHO classification of tumours of the breast they are divided into three morphologically distinct categories....
Sun Aug 23, 2020 13:47
Related Articles Uncommon Subtypes of Malignant Melanomas: A Review Based on Clinical and Molecular Perspectives. Cancers (Basel). 2020 Aug 21;12(9): Authors: Chacón M, Pfluger Y, Angel M, Waisberg F, Enrico D Abstract Malignant melanoma represents the most aggressive type of skin cancer. Modern therapies, including targeted agents and immune checkpoint inhibitors, have changed the dismal prognosis that characterized this disease. However, most...
Sun Aug 23, 2020 13:47
Related Articles Age at Onset and Presenting Symptoms of Neurofibromatosis Type 2 as Prognostic Factors for Clinical Course of Vestibular Schwannomas. Cancers (Basel). 2020 Aug 20;12(9): Authors: Gugel I, Grimm F, Zipfel J, Teuber C, Ernemann U, Kluwe L, Tatagiba M, Mautner VF, Schuhmann MU Abstract The presenting symptoms of the tumor suppressor gene syndrome neurofibromatosis type 2 (NF2) are often non-specific and unrelated to the disease...
Sun Aug 23, 2020 13:47
Related Articles Low Incidence of SARS-CoV-2 in Patients with Solid Tumours on Active Treatment: An Observational Study at a Tertiary Cancer Centre in Lombardy, Italy. Cancers (Basel). 2020 Aug 20;12(9): Authors: Bertuzzi AF, Marrari A, Gennaro N, Cariboni U, Ciccarelli M, Giordano L, Quagliuolo VL, Santoro A Abstract Background: The incidence and prognosis of SARS-CoV-2-positive cancer patients on active oncologic treatment remain unknown....
Sun Aug 23, 2020 13:47
Related Articles Identification of Novel Fusion Genes in Bone and Soft Tissue Sarcoma and Their Implication in the Generation of a Mouse Model. Cancers (Basel). 2020 Aug 19;12(9): Authors: Teramura Y, Tanaka M, Yamazaki Y, Yamashita K, Takazawa Y, Ae K, Matsumoto S, Nakayama T, Kaneko T, Musha Y, Nakamura T Abstract Fusion genes induced by chromosomal aberrations are common mutations causally associated with bone and soft tissue sarcomas (BSTS)....
Sun Aug 23, 2020 13:47
Related Articles Trends in Bone Metastasis Modeling. Cancers (Basel). 2020 Aug 17;12(8): Authors: Laranga R, Duchi S, Ibrahim T, Guerrieri AN, Donati DM, Lucarelli E Abstract Bone is one of the most common sites for cancer metastasis. Bone tissue is composed by different kinds of cells that coexist in a coordinated balance. Due to the complexity of bone, it is impossible to capture the intricate interactions between cells under either physiological...
Sun Aug 23, 2020 13:47
Related Articles Evolution of the Experimental Models of Cholangiocarcinoma. Cancers (Basel). 2020 Aug 17;12(8): Authors: Massa A, Varamo C, Vita F, Tavolari S, Peraldo-Neia C, Brandi G, Rizzo A, Cavalloni G, Aglietta M Abstract Cholangiocarcinoma (CCA) is a rare, aggressive disease with poor overall survival. In advanced cases, surgery is often not possible or fails; in addition, there is a lack of effective and specific therapies. Multidisciplinary...
Sun Aug 23, 2020 13:47
Related Articles Phase II Clinical Trial of Pembrolizumab in Patients with Progressive Metastatic Pheochromocytomas and Paragangliomas. Cancers (Basel). 2020 Aug 16;12(8): Authors: Jimenez C, Subbiah V, Stephen B, Ma J, Milton D, Xu M, Zarifa A, Akhmedzhanov FO, Tsimberidou A, Habra MA, Rodon Anhert J, Fu S, Naing A Abstract Metastatic pheochromocytomas and paragangliomas (MPPGs) are rare endocrine malignancies that are associated with high...
Sun Aug 23, 2020 13:47
Related Articles NECTIN4 Expression in Extramammary Paget's Disease: Implication of a New Therapeutic Target. Int J Mol Sci. 2020 Aug 16;21(16): Authors: Murata M, Ito T, Tanaka Y, Kaku-Ito Y, Furue M Abstract Extramammary Paget's disease (EMPD) is a rare skin cancer arising in the anogenital area. Most EMPD tumors remain dormant as in situ lesions, but the outcomes of patients with metastatic EMPD are poor because of the lack of effective systemic...
Sun Aug 23, 2020 13:47
Related Articles Health-Related Quality of Life and Experiences of Sarcoma Patients during the COVID-19 Pandemic. Cancers (Basel). 2020 Aug 14;12(8): Authors: Younger E, Smrke A, Lidington E, Farag S, Ingley K, Chopra N, Maleddu A, Augustin Y, Merry E, Wilson R, Benson C, Miah A, Zaidi S, McTiernan A, Strauss SJ, Dileo P, Gennatas S, Husson O, Jones RL Abstract Sarcomas are rare cancers with a spectrum of clinical needs and outcomes. We investigated...
Sun Aug 23, 2020 13:47
CD70 antibody-drug conjugate as a potential therapeutic agent for uterine leiomyosarcoma. Am J Obstet Gynecol. 2020 Aug 18;: Authors: Nakae R, Matsuzaki S, Serada S, Matsuo K, Shiomi M, Sato K, Nagase Y, Matsuzaki S, Nakagawa S, Hiramatsu K, Okazawa A, Kimura T, Egawa-Takata T, Kobayashi E, Ueda Y, Yoshino K, Naka T, Kimura T Abstract BACKGROUND: Uterine leiomyosarcoma is a rare and aggressive gynecologic malignancy originating in the myometrium...
Sat Aug 22, 2020 13:27
Related Articles [Results of surgical and radiotherapeutic treatment of adenoid cystic carcinoma of the salivary glands]. HNO. 2020 Aug 21;: Authors: Bastian T, D'Heygere V, Deuß E, Lax H, Wittig A, Sauerwein W, Arweiler-Harbeck D Abstract Surgical treatment in patients with rare adenoid cystic carcinoma (ACC) of the salivary glands is considered to be the state of the art. With respect to an additional radiotherapy there are different approaches...
Sat Aug 22, 2020 13:27
Related Articles Complete response in anaplastic lymphoma kinase-rearranged oncocytic thyroid cancer: A case report and review of literature. World J Clin Oncol. 2020 Jul 24;11(7):495-503 Authors: de Salins V, Loganadane G, Joly C, Abulizi M, Nourieh M, Boussion H, Belkacemi Y, Tournigand C, Kempf E Abstract BACKGROUND: Oncocytic carcinoma of the thyroid is a rare disease, characterized by a poor prognosis and low response rate to radioiodine...
Sat Aug 22, 2020 13:27
Related Articles When, why and how tumour clonal diversity predicts survival. Evol Appl. 2020 Aug;13(7):1558-1568 Authors: Noble R, Burley JT, Le Sueur C, Hochberg ME Abstract The utility of intratumour heterogeneity as a prognostic biomarker is the subject of ongoing clinical investigation. However, the relationship between this marker and its clinical impact is mediated by an evolutionary process that is not well understood. Here, we employ...
Sat Aug 22, 2020 13:27
Related Articles Human Endogenous Retroviruses in Clear Cell Renal Cell Carcinoma: Biological Functions and Clinical Values. Onco Targets Ther. 2020;13:7877-7885 Authors: Cao W, Kang R, Xiang Y, Hong J Abstract Human endogenous retroviruses (HERVs) form an important part of the human genome, commonly losing their coding ability and exhibiting only rare expression in healthy tissues to promote the stability of the genome. However, overexpression...
Sat Aug 22, 2020 13:27
Related Articles SET-CAN Fusion Gene in Acute Leukemia and Myeloid Neoplasms: Report of Three Cases and a Literature Review. Onco Targets Ther. 2020;13:7665-7681 Authors: Zhang H, Zhang L, Li Y, Gu H, Wang X Abstract Objective: To investigate the characteristics of hematological malignancies in patients with the SET-CAN fusion gene and provide a literature review. Methods: We retrospectively analyzed the clinical data of three cases...
Sat Aug 22, 2020 13:27
Related Articles Double primary malignant tumor in a centenarian female: Case report and review of literature. Nepal J Ophthalmol. 2019 Jul;11(22):223-226 Authors: Shrivastava AK, Nanda S Abstract A hundred and three year old female patient was evaluated for ulcer over the nasion area and a mass arising from the right upper eyelid, appearing two months apart. Histopathology revealed nasion ulcer as basal cell carcinoma while right eyelid mass...
Sat Aug 22, 2020 13:27
Related Articles Epidemiology and clinical features of intraocular lymphoma in Singapore. Nepal J Ophthalmol. 2019 Jul;11(22):158-166 Authors: Hah YY, Ho SL, Beng SC, Agrawal R Abstract INTRODUCTION: Intraocular lymphoma is rare. There are very few studies on intraocular lymphoma published from Asian countries. OBJECTIVE: To report our case series of intraocular lymphoma patients from a tertiary eye centre in Singapore. SUBJECTS...
Sat Aug 22, 2020 13:27
Related Articles Optical coherence tomography angiography findings of choroidal neovascularization secondary to decalcified choroidal osteoma treated with intravitreal aflibercept: A case report. Medicine (Baltimore). 2020 Jul 24;99(30):e21472 Authors: Yao B, Wang F, Zhao X, Wang B, Liu G, Ding Y Abstract INTRODUCTION: Choroidal osteoma (CO) is a rare benign ocular tumor characterized by ossifying choroid lesions. To the best of our knowledge,...
Sat Aug 22, 2020 13:27
Related Articles A nationwide analysis of desmoplastic small round cell tumor. Medicine (Baltimore). 2020 Jul 24;99(30):e21337 Authors: Xiang T, Zhang SY, Wang SS, Fei RS, Li H Abstract This study aim is to enhance the understanding, diagnosis and treatment of desmoplastic small round cell tumor (DSRCT) and to determine what factors can affect survival of the disease in China.We report here 8 patients with DSRCT in our center who received a...
Sat Aug 22, 2020 13:27
Related Articles Primary ovarian small cell carcinoma of hypercalcemic type in a pregnant woman: A case report. Medicine (Baltimore). 2020 Jul 24;99(30):e20387 Authors: Feng M, Yang K, Xu L, Zhang Y, Zou J Abstract RATIONALE: Ovarian small cell carcinoma of hypercalcemic type (OSCCHT) is a relatively rare and highly fatal gynecological malignancy of unknown histogenesis, affecting mainly girls and young women. OSCCHT occurring during pregnancy...
Sat Aug 22, 2020 13:27
Related Articles Cerebral and pulmonary aspergillosis, treatment and diagnostic challenges of mixed breakthrough invasive fungal infections: case report study. BMC Infect Dis. 2020 Jul 23;20(1):535 Authors: Amanati A, Lotfi M, Masoudi MS, Jafarian H, Ghasemi F, Bozorgi H, Badiee P Abstract BACKGROUND: Breakthrough invasive fungal infections (bIFIs) are an area of concern in the scarcity of new antifungals. The mixed form of bIFIs is a rare...
Sat Aug 22, 2020 13:27
Related Articles Cabozantinib in patients with platinum-refractory metastatic urothelial carcinoma: an open-label, single-centre, phase 2 trial. Lancet Oncol. 2020 08;21(8):1099-1109 Authors: Apolo AB, Nadal R, Tomita Y, Davarpanah NN, Cordes LM, Steinberg SM, Cao L, Parnes HL, Costello R, Merino MJ, Folio LR, Lindenberg L, Raffeld M, Lin J, Lee MJ, Lee S, Alarcon SV, Yuno A, Dawson NA, Allette K, Roy A, De Silva D, Lee MM, Sissung TM, Figg WD, Agarwal PK, Wright...
Sat Aug 22, 2020 13:27
Related Articles Resecting a giant malignant lung tumor in a patient with unilateral acute interstitial pneumonitis. Respir Investig. 2020 May;58(3):220-224 Authors: Yabuki H, Minowa M, Adachi Y, Hara Y, Katsumata H, Matsuura Y Abstract Acute interstitial pneumonia is a rare and fulminant form of idiopathic interstitial lung disease. Here, we report a case of a giant malignant sarcomatoid tumor of the left lung with unilateral lung infiltration....
Sat Aug 22, 2020 13:27
Related Articles Prevalence and Sonographic Detection of Gallbladder Polyps in a Western European Population. J Surg Res. 2020 06;250:226-231 Authors: Pickering O, Pucher PH, Toale C, Hand F, Anand E, Cassidy S, McEntee G, Toh SKC Abstract BACKGROUND: Gallbladder cancer is rare but associated with significant morbidity and mortality necessitating the early identification of premalignant and malignant lesions to improve overall prognosis. Despite...
Sat Aug 22, 2020 13:27
Related Articles [Dermatomyositis associated with hepatitis B virus-related hepatocellular carcinoma: a case report in Peru]. Rev Gastroenterol Peru. 2019 Oct-Dec;39(4):374-377 Authors: Cuadros-Torres M, Ganoza-Calero AM, Plácido Z, Prado B J Abstract Dermatomyositis is an idiopathic inflammatory myopathie characterized by proximal skeletal muscle weakness, typical skin manifestations and muscle inflammation. This disease has been associated...
Sat Aug 22, 2020 13:27
Related Articles 18F-FDG PET/CT Finding of Primary Cardiac Lymphoma. Clin Nucl Med. 2020 Apr;45(4):319-321 Authors: Kaida H, Kumode T, Kimura M, Ishii K Abstract An 80-year-old woman experienced dyspnea. Cardiac enlargement was detected by chest radiography at a local hospital. She was admitted to our hospital, and echocardiography and CT revealed pericardial effusion and multiple tumor lesions in right atrium. F-FDG PET/CT demonstrated multiple...
Sat Aug 22, 2020 13:27
Related Articles Primary Paravertebral Germ Cell Tumor Demonstrated by FDG PET/CT. Clin Nucl Med. 2020 Apr;45(4):322-323 Authors: Wang R, Su M, Tian R Abstract Extragonadal germ cell tumors are rare. Most of these tumors occur in the anterior mediastinum, retroperitoneum, pineal gland, or suprasellar region. Here, we present a case of a 29-year-old man with a paravertebral mass to the right of the T8 and T9 vertebral bodies on MRI and FDG PET/CT....
Sat Aug 22, 2020 13:27
Related Articles Pancreatic Adenocarcinoma Causing Necrotizing Pancreatitis: Not as Rare as You Think? J Surg Res. 2020 06;250:53-58 Authors: Lewellen KA, Maatman TK, Heimberger MA, Ceppa EP, House MG, Nakeeb A, Schmidt CM, Zyromski NJ Abstract BACKGROUND: Necrotizing pancreatitis (NP) presents a unique clinical challenge because of its complex and lengthy disease course. Pancreatic necrosis occurs in 10%-20% of acute pancreatitis cases and...
Sat Aug 22, 2020 13:27
Related Articles Rare Esophageal Leptomeningeal Metastases Detected on 18F-FDG PET/CT. Clin Nucl Med. 2020 Apr;45(4):334-335 Authors: Lu Y, Wang L, Ajani JA Abstract A 62-year-old man with a history of locally advanced poorly differentiated adenocarcinoma of the gastroesophageal junction had received induction chemotherapy and concurrent chemoradiation. A 6-month follow-up FDG PET/CT revealed nearly resolved primary malignancy, but new hypermetabolic...
Sat Aug 22, 2020 13:27
Related Articles A Rare Presentation of Melanoma as a Retroperitoneal Mass Seen on FDG PET. Clin Nucl Med. 2020 Apr;45(4):324-325 Authors: Yao Y, Liu W, Zuo Z, Cheng Z Abstract A 55-year-old woman presented with intermittent fatigue and abdominal pain. Ultrasound and CT scan showed a large heterogeneous mass in the retroperitoneum, suggestive of malignancy. F-FDG PET/CT was performed for staging. PET/CT images showed a hypermetabolic retroperitoneal...
Sat Aug 22, 2020 13:27
Related Articles The Complementary Role of 68Ga-DOTATATE PET/CT in Neuroblastoma. Clin Nucl Med. 2020 Apr;45(4):326-329 Authors: Telli T, Lay Ergün E, Volkan Salanci B, Özgen Kiratli P Abstract A girl diagnosed with neuroblastoma at 33 months underwent I-MIBG scan after surgery and chemoradiotherapy. Although MIBG scan showed complete response, the bone marrow biopsy showed refractory disease. Therefore, she underwent Ga-DOTATATE PET/CT, which...
Sat Aug 22, 2020 13:27
Related Articles Ovarian Metastasis as Initial Presentation of Pancreatic Carcinoma on FDG PET/CT. Clin Nucl Med. 2020 Apr;45(4):306-307 Authors: Hou G, Jiang Y, Li F, Cheng X Abstract Pancreatic carcinoma metastasizing to the ovary is rare. We report the case of a 69-year-old woman with ovarian metastasis as initial presentation. Ultrasonography revealed a multicystic mass in the right adnexa, which was considered a malignancy. FDG PET/CT...
Sat Aug 22, 2020 13:27
Related Articles A Rare Case of Intradural Extramedullary Ewing's Sarcoma in the Cervical Region. Neurol India. 2019 Nov-Dec;67(6):1543-1544 Authors: Warade AC, Jha AK, Pattankar S, Madiwale C, Rekhi B, Desai K PMID: 31857557 [PubMed - indexed for MEDLINE]
Sat Aug 22, 2020 13:27
Related Articles Rare BRIP1 Missense Alleles Confer Risk for Ovarian and Breast Cancer. Cancer Res. 2020 02 15;80(4):857-867 Authors: Moyer CL, Ivanovich J, Gillespie JL, Doberstein R, Radke MR, Richardson ME, Kaufmann SH, Swisher EM, Goodfellow PJ Abstract Germline loss-of-function mutations in BRCA1 interacting protein C-terminal helicase 1 (BRIP1) are associated with ovarian carcinoma and may also contribute to breast cancer risk, particularly...
Sat Aug 22, 2020 13:27
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