Publication date: October 2020Source: Acta Histochemica, Volume 122, Issue 7Author(s): Ren-jian Zheng, Jin-lin Song, Xiao-hong Wu, David C. Watts
Sun Aug 23, 2020 17:57
Publication date: Available online 22 August 2020Source: Annals of Diagnostic PathologyAuthor(s): Xavier Catteau, Caroline Koopmansch, Calliope Maris, Patrick Colart, Jean-Christophe Noël
Sat Aug 22, 2020 19:12
Publication date: Available online 21 August 2020Source: Annals of Diagnostic PathologyAuthor(s): Lorena Di Pasquale Guadalupe, José De Jesús, Yin Xiong, Marilin Rosa
Sat Aug 22, 2020 19:12
Publication date: Available online 21 August 2020Source: Annals of Diagnostic PathologyAuthor(s): Ayesha Farooq, John J. Evans, Catherine E. Hagen, Christopher P. Hartley
Fri Aug 21, 2020 15:16
Publication date: Available online 21 August 2020Source: Annals of Diagnostic PathologyAuthor(s): Leonardo Franz, Lara Alessandrini, Tommaso Saccardo, Anna Chiara Frigo, Gino Marioni
Fri Aug 21, 2020 15:16
Publication date: Available online 21 August 2020Source: Annals of Diagnostic PathologyAuthor(s): Oleksandr Kravtsov, Christopher P. Hartley, Yuri Sheinin, Bryan C. Hunt, Juan C. Felix, Tamara Giorgadze
Fri Aug 21, 2020 15:16
Publication date: Available online 21 August 2020Source: Annals of Diagnostic PathologyAuthor(s): Olawande Damilola Bamisi, Margaret Olutayo Alese
Fri Aug 21, 2020 15:16
Publication date: Available online 21 August 2020Source: Annals of Diagnostic PathologyAuthor(s): Kirsten S. Hegg, Lloyd A. Mack, Antoine Bouchard-Fortier, Walley J. Temple, Xianyong Gui
Fri Aug 21, 2020 15:16
Degradation of extracellular matrix (ECM) in intervertebral disks (IVDs) during IVD degeneration plays a vital role in low back pain (LBP). In healthy IVDs, synthesis and degradation of ECM are kept in balance by matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs. MMPs are enzymes responsible for ECM degradation, and their expression levels are known to increase in degenerated disks. However, the exact pathophysiological concentration of MMP-1 in the degenerated disks of patients with...
Fri Aug 21, 2020 09:06
Abstract Background The accurate preoperative identification of medullary thyroid carcinoma (MTC) is challenging due to the rarity of tumor and variable cytologic appearance. The Asian experience with diagnosing MTC by fine‐needle aspiration (FNA) was scarcely reported. Methods Cases of MTC with available FNA slides were enrolled from 13 hospitals representing 8 Asia‐Pacific countries. Clinicopathological information, including sample preparation technique, staining method, original cytologic...
Sat Aug 22, 2020 16:14
Abstract Pleomorphic adenoma (PA) is the most common benign salivary gland tumor characterized by morphological diversity, metaplastic changes, degeneration, cystic change, altered differentiation, and rarely malignant transformation, thereby may create a diagnostic dilemma on cytology. Xanthogranulomatous (XG) inflammation within a PA could be due to XG sialadenitis coexistent with PA or preoperative fine‐needle aspiration cytology (FNAC) induced histologic alteration. The argument in favor of...
Fri Aug 21, 2020 18:52
Abstract Objective A variety of models are used for fine needle aspiration biopsy (FNAB) and smear preparation techniques training: human, animal and silicon models or combined models. We present fresh animal tissues as models for freehand and ultrasound (US)‐guided FNAB technique training, enabling an integrated approach from tumour detection to smear evaluation. Methods We introduced a novel combined animal tissue model using dietary animal meat with covering skin as a substrate. Animal...
Fri Aug 21, 2020 18:51
Abstract A 70‐year‐old female presented with a swelling in the right auricle for 6 months. Rapid onsite stain and routine cytology revealed clusters of small, round to oval cells with hyperchromatic nuclei, inconspicuous nucleoli, and scant cytoplasm. The background had basement membrane type material and appeared dark magenta colored pinkish globular material. Hence a cytological diagnosis of skin adnexal tumor possibly cylindroma was made. The excision of the lesion also showed features of cylindroma....
Fri Aug 21, 2020 18:50
Abstract Background Lung adenocarcinomas present as tight clusters and three‐dimensional balls in effusion specimens. Unlike carcinomas of breast and stomach where singly lying malignant cells are seen in effusion samples, lung adenocarcinomas usually show cohesive morphology. This single‐cell pattern may also be confused with reactive mesothelial cells. We studied the frequency of pulmonary adenocarcinoma with single‐cell pattern cytomorphology in pleural effusion specimens. Materials and...
Thu Aug 20, 2020 19:28
Abstract Liver is the most common site for metastasis of colonic adenocarcinoma. Other relatively common metastatic locations include: peritoneum, lungs and ovaries. Rare metastatic sites include: central nervous system, testis, uterus, oral cavity and bones. Though it is rare to have an isolated bone metastasis without liver or visceral involvement in colonic adenocarcinoma, it can occur. Our case illustrates the vital role of an accurate cytopathologic diagnosis in directing the proper clinical...
Thu Aug 20, 2020 16:20
Abstract Follicular dendritic cell sarcoma (FDCS) is a rare malignant neoplasm of follicular dendritic cell origin which can present a diagnostic challenge. Due to the rarity of this neoplasm, its molecular pathogenesis has not been fully elaborated. A previous series of 13 cases reported that 38% contained mutations of genes encoding proteins involved in negative regulation of NF‐κB. NF‐κB is a family of transcription factors regulated through multiple cellular processes known as the canonical...
Thu Aug 20, 2020 16:18
Abstract A surgical case of a benign notochordal cell tumor of the lung is reported. The patient was an asymptomatic 41‐year‐old man, who was incidentally found to have a small tumor in the subpleural region of the left lingular segment. Since wedge resection of the tumor, the patient has been free from recurrence. The tumor measured 12 mm in diameter and showed a central cystic change. It consisted of a diffuse proliferation of polygonal cells with abundant, uni‐ or multi‐vacuolated cytoplasm and...
Sat Aug 22, 2020 13:44
Publication date: Available online 21 August 2020Source: Pathology - Research and PracticeAuthor(s): Stephanie Kaiser, Sascha Lang, Dominik Gross
Sat Aug 22, 2020 21:50
Abstract Obese patients, often accompanied by hyperleptinemia, are prone to develop liver fibrosis. A large body of data including the results from human studies suggested the promotion role of leptin, an adipocyte‐derived hormone, in liver fibrosis. Hepatic stellate cell (HSC) activation, a crucial step in liver fibrogenesis, requires global reprogramming of gene expression which is regulated by multiple mechanisms including epigenetic regulation such as methylation of DNA. S‐adenosylmethionine...
Sat Aug 22, 2020 13:08
Abstract Bronchopulmonary dysplasia (BPD), a chronic lung disease in premature infants, results from mechanical ventilation and hyperoxia amongst other factors. Although most BPD survivors can be weaned from supplemental oxygen, many show evidence of cardiovascular sequelae in adulthood, including pulmonary hypertension and pulmonary vascular remodeling. Endothelial‐mesenchymal transition (EndoMT) plays an important role in mediating vascular remodeling in idiopathic pulmonary arterial hypertension....
Thu Aug 20, 2020 11:45
Abstract Recent genetic analyses revealed genetic heterogeneity in hepatocellular carcinoma (HCC), although it remains unclear how genetic alterations contribute to the multistage progression of HCC, especially the early step from hypovascular liver nodules to hypervascular HCC. We conducted multiregional whole‐genome sequencing on HCCs with a nodule‐in‐nodule appearance, consisting of inner hypervascular HCC surrounded by hypovascular HCC arising from a common origin, and identified point mutations,...
Thu Aug 20, 2020 11:42
Abstract Clear cell renal cell carcinoma (ccRCC) is the most common form of renal cancer. Due to inactivation of the von Hippel Lindau tumour suppressor, the hypoxia inducible transcription factors (HIFs) are constitutively activated in these tumours, resulting in a pseudo‐hypoxic phenotype. The HIFs induce the expression of genes involved in angiogenesis and cell survival, but they also reset the cellular metabolism to protect cells from oxygen and nutrient deprivation. ccRCC tumours are highly...
Thu Aug 20, 2020 11:38
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου