Abstract With the development of chemotherapy regimens, targeted therapies, and hepatic surgery, the survival of patients with colorectal liver metastases (CRLM) has dramatically improved. Imaging plays a central role for the diagnosis, staging, and treatment allocation in these patients. To interpret CRLM on imaging, radiologists must be familiar with the main imaging features of untreated tumors as well as the modifications induced by systemic therapies, and their meaning...
Abstract Injected drug use is associated with a wide range of medical complications which are predominantly musculoskeletal and vascular in nature. Illicit drug use is increasing worldwide. Patients with complications of injected drug use often present in a non-specific manner without a reliable clinical history. Musculoskeletal complications are typically infective in aetiology and may vary widely in severity from mild to life-threatening. A multimodal imaging approach is often...
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Abstract Circular dichroism (CD) spectroscopy is highly sensitive to the secondary structure (SS) composition of proteins. Several methods exist to either estimate the SS composition of a protein or to validate existing structural models using its CD spectrum. The accuracy and precision of these methods depend on the quality of both the measured CD spectrum and the used reference structure. Using a large reference protein set with high-quality CD spectra and synthetic data derived...
Abstract The 6-deoxy-6-aminocelluloses—or “aminocelluloses”—are a class of synthetic natural cellulose derivatives which are mostly aqueous soluble and have excellent film-forming properties. Recent studies have connected these properties at the molecular level with protein-like self-associative behaviour for a range of aminocelluloses including a 6-deoxy-6-(ω-aminoethyl) aminocellulose AEA-1 with the association being a two-stage process—a reversible oligomerisation followed by...
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Current Anthropology, Ahead of Print.
Current Anthropology, Ahead of Print.
Current Anthropology, Ahead of Print.
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Plant pathogens cause widespread yield losses in agriculture. Understanding the drivers of plant-pathogen interactions requires decoding the molecular dialog leading to either resistance or disease. However, progress in deciphering pathogenicity genes has been severely hampered by suitable model systems and incomplete fungal genome assemblies. Here, we report a significant improvement of the assembly and annotation of the genome of the Fusarium oxysporum (Fo) strain Fo5176. Fo comprises a large number...
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Publication date: Available online 24 August 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): Ian Jenkyn, Kishan Patel, Claire Jenkyn, Shadi Basyuni, Shagorika Talukder, Malcolm Cameron
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Abstract Introduction Mechanical stimuli regulate Sclerostin (Scl), a negative regulator of bone formation, expression in osteocytes. However, the detailed Scl distribution in osteocytes in response to mechanical unloading remains unclear. Materials and methods Twelve-week-old male rats were used. The sciatic and femoral nerves on the right side were...
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Abstract According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance aminopyralid. To assess the occurrence of aminopyralid residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Commission Regulation (EU) No 188/2011, the MRLs established by the Codex Alimentarius Commission as well as the European...
Abstract According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance Pseudomonas sp. strain DSMZ 13134. To assess the occurrence of Pseudomonas sp. strain DSMZ 13134 residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Commission Regulation (EU) No 188/2011, as well as the European authorisations...
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Abstract The epistemic attitudes of scientists, such as epistemic tolerance and authoritarianism, play important roles in the discourse about rivaling theories. Epistemic tolerance stands for the mental attitude of an epistemic agent, e.g., a scientist, who is open to opposing views, while epistemic authoritarianism represents the tendency to uncritically accept views of authorities. Another relevant epistemic factor when it comes to the epistemic decisions of scientists is the...
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Abstract Size and development time are universally important traits. Yet evolutionary trends in development time are often viewed as allometric and physiological by-products of initial size, when life-history theory predicts that both traits are targets of selection and evolve adaptively through opposing effects on fitness. Surprisingly, this prediction has rarely been tested by disentangling the direct and indirect effects of size and development time on fitness, as necessary...
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Scientists have identified a new ichnospecies from the shell of an extinct marine turtle fossil, the first known species coexisting on living marine vertebrates.
A new scientific study has revealed unique life strategies of two major groups of microbes that live below Earth's surface. These groups, originally thought to rely on symbiotic relationships with other organisms, may also live independently and use an ancient mode of energy production.
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Publication date: Available online 25 August 2020Source: Magnetic Resonance ImagingAuthor(s): Sara Doimo, Fabrizio Ricci, Nay Aung, Jackie Cooper, Redha Boubertakh, Mihir M. Sanghvi, Gianfranco Sinagra, Steffen E. Petersen
Publication date: Available online 24 August 2020Source: Magnetic Resonance ImagingAuthor(s): Kiichi Tadano, Yoshikazu Okamoto, Tomonori Isobe, Shintaro Mori, Hiroaki Suzuki, Manabu Minami, Takeji Sakae
Publication date: Available online 24 August 2020Source: Magnetic Resonance ImagingAuthor(s): Hirohito Kan, Yuto Uchida, Nobuyuki Arai, Masahiro Takizawa, Tosiaki Miyati, Hiroshi Kunitomo, Harumasa Kasai, Yuta Shibamoto
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Abstract Objectives The aim of this prospective cohort study was to investigate the associations between maternal vitamin D status in late pregnancy and emergency caesarean section (EMCS) and birth asphyxia, in a population based sample of women in Sweden. Methods Pregnant women were recruited at the antenatal care in Sweden and 1832 women were included...
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Studies on marine community dynamics and population structures are limited by the lack of exhaustive knowledge on the larval dispersal component of connectivity. Genetic data represents a powerful tool in unde...
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Publication date: Available online 25 August 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Maria Alves Garcia Silva, Letícia Lopes Quirino Pantoja, Kamile Leonardi Dutra-Horstmann, José Valladares-Neto, Felipe Lucyk Wolff, André Luís Porporatti, Eliete Neves Silva Guerra, Graziela De Luca Canto
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