A Rare Case of an Immunocompetent Male With Zoster Meningitis

Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Varicella zoster meningitis is an uncommon complication of herpes zoster, especially in immunocompetent patients. We report a case of a healthy 45-year-old male who developed aseptic meningitis as a result of reactivated varicella zoster virus infection. This case highlights the importance of remaining cognizant of varicella zoster virus as a cause of meningitis in not only the elderly or immunocompromised...

SAGE Publications: Journal of Investigative Medicine High Impact Case Reports: Table of Contents

Mon Aug 24, 2020 13:39

IgG4-Related Disease Manifesting as Hypocomplementemic Tubulointerstitial Nephritis: A Rare Case Report and Literature Review

Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Immunoglobulin G4–related disease (IgG4-RD) is a chronic fibrosing inflammatory systemic disorder that has been recognized relatively recently in the medical literature. Little is known about the exact disease pathogenesis and epidemiology. IgG4-RD may be asymptomatic or may have minimal symptoms or involve multiple organs with overt symptoms. The different phenotypes of IgG4-RD can lead to delayed...

SAGE Publications: Journal of Investigative Medicine High Impact Case Reports: Table of Contents

Mon Aug 24, 2020 13:38

Pembrolizumab-Induced Diabetes Mellitus Presenting as Diabetic Ketoacidosis in a Patient With Metastatic Colonic Adenocarcinoma

Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Immunotherapy drugs are gaining popularity in the treatment of certain malignancies due to the success of these agents in recent clinical trials. Pembrolizumab is an immune checkpoint inhibitor that acts via binding to programmed cell death 1 (PD-1) receptors on T-cells, allowing for the constitutive activation of T-cells to fight malignant tumor cells. Immune checkpoint molecules such as PD-1 act...

SAGE Publications: Journal of Investigative Medicine High Impact Case Reports: Table of Contents

Mon Aug 24, 2020 13:38

Drug-Induced Liver Injury: A Unique Presentation of Single-Dose Administration of Propylthiouracil

Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Antithyroid drug-induced severe liver injury is an uncommon but serious complication. We hereby delineate the case of a 38-year-old female who presented to the emergency department for an impending thyroid storm. After initiation of a single dose of propylthiouracil, her liver enzymes went into the thousands. She was subsequently admitted to the intensive care unit. Propylthiouracil was discontinued...

SAGE Publications: Journal of Investigative Medicine High Impact Case Reports: Table of Contents

Mon Aug 24, 2020 13:38