Related Articles Analysis of prognostic factors for Tis-2N0M0 early glottic cancer with different treatment methods. Braz J Otorhinolaryngol. 2020 Aug 06;: Authors: Wang G, Li G, Wu J, Song P Abstract INTRODUCTION: In many regions, laryngeal carcinoma is a common upper respiratory tract cancer, most commonly involving the glottic region. The treatment of early glottic cancer includes radiotherapy, open surgery and laryngeal laser microsurgery....
Tue Aug 25, 2020 16:41
Related Articles Extending Peer Support Across the Military Health System to Decrease Clinician Burnout. Mil Med. 2020 Aug 22;: Authors: Keyser EA, Weir LF, Valdez MM, Aden JK, Matos RI Abstract INTRODUCTION: Clinician burnout is widespread throughout medicine, affecting professionalism, communication, and increases the risk of medical errors, thus impacting safe quality patient care. Previous studies have shown Peer Support Programs (PSPs)...
Tue Aug 25, 2020 15:15
Related Articles Automated Partial Versus Complete Resuscitative Endovascular Balloon Occlusion of the Aorta for the Management of Hemorrhagic Shock in a Pig Model of Polytrauma: a Randomized Controlled Pilot Study. Mil Med. 2020 Aug 22;: Authors: Hoareau GL, Beyer CA, Caples CA, Spruce MW, Kevin Grayson J, Neff LP, Williams TK, Johnson MA Abstract INTRODUCTION: Endovascular variable aortic control (EVAC) is an automated partial resuscitative...
Tue Aug 25, 2020 15:15
Related Articles Novel Algorithm for Automated Optic Nerve Sheath Diameter Measurement Using a Clustering Approach. Mil Med. 2020 Aug 22;: Authors: Rajajee V, Soroushmehr R, Williamson CA, Najarian K, Gryak J, Awad A, Ward KR, Tiba MH Abstract INTRODUCTION: Using ultrasound to measure optic nerve sheath diameter (ONSD) has been shown to be a useful modality to detect elevated intracranial pressure. However, manual assessment of ONSD by a human...
Tue Aug 25, 2020 15:15
Related Articles Tumor associated neutrophils promote the metastasis of pancreatic ductal adenocarcinoma. Cancer Biol Ther. 2020 Aug 23;:1-9 Authors: Lianyuan T, Gang L, Ming T, Dianrong X, Chunhui Y, Zhaolai M, Bin J Abstract The aim of this study was to investigate the role of tumor-associated neutrophils (TANs) in the metastasis of pancreatic ductal adenocarcinoma (PDAC), to explore the regulation of TANs, and to determine the mechanisms...
Tue Aug 25, 2020 18:37
Related Articles Analysis of selective target engagement by small-molecule sphingosine kinase inhibitors using the Cellular Thermal Shift Assay (CETSA). Cancer Biol Ther. 2020 Aug 23;:1-12 Authors: Hengst JA, Dick TE, Smith CD, Yun JK Abstract The recently renewed interest in scientific rigor and reproducibility is of critical importance for both scientists developing new targeted small-molecule inhibitors and those employing these molecule...
Tue Aug 25, 2020 18:37
Related Articles Enhanced antitumor effect of alectinib in combination with cyclin-dependent kinase 4/6 inhibitor against RET-fusion-positive non-small cell lung cancer cells. Cancer Biol Ther. 2020 Aug 23;:1-8 Authors: Fujimura T, Furugaki K, Harada N, Yoshimura Y Abstract Rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC) accounts for 1% of lung adenocarcinoma. Although small molecule agents with RET kinase...
Tue Aug 25, 2020 18:37
Related Articles Radiotherapy for patients with stage IV classical Hodgkin lymphoma: a propensity-matched analysis of the surveillance, epidemiology, and end results database. Cancer Biol Ther. 2020 Aug 23;:1-9 Authors: Wang S, Jia M, Han J, Zhang R, Huang K, Li P, Li Q, Qiao Y, Song Q, Fu Z Abstract Background The survival advantage of radiotherapy for patients with stage IV classic Hodgkin lymphoma (HL) has not been adequately evaluated. Methods...
Tue Aug 25, 2020 18:37
Related Articles First-attempt intubation success and complications in patients with COVID-19 undergoing emergency intubation. J Am Coll Emerg Physicians Open. 2020 Aug 12;: Authors: de Alencar JCG, Marques B, Marchini JFM, Marino LO, Ribeiro SCDC, Bueno CG, da Cunha VP, Lazar Neto F, Valente FS, Rahhal H, Pereira JBR, Padrão EMH, Wanderley APB, Costa MGP, Brandão Neto RA, Souza HP Abstract Objectives: To evaluate the first-attempt success rates...
Tue Aug 25, 2020 17:04
Fine Governance of Difficult Tracheostomy in Difficult Airway with Stridor and Respiratory Distress.
Related Articles Fine Governance of Difficult Tracheostomy in Difficult Airway with Stridor and Respiratory Distress. Indian J Otolaryngol Head Neck Surg. 2020 Jul 21;:1-4 Authors: Soni S, Chacko A, Poorey VK Abstract Difficult airway is a commonly encountered problem in the anesthesia practice, might needing otolaryngologist expert in creation of surgical airway. Supraglottic airways, surgical or needle cricothyrotomy, high frequency jet ventilation,...
Tue Aug 25, 2020 17:04
Related Articles The role of ultrasound in front-of-neck access for cricothyroid membrane identification: A systematic review. J Crit Care. 2020 Aug 13;60:161-168 Authors: Rai Y, You-Ten E, Zasso F, De Castro C, Ye XY, Siddiqui N Abstract PURPOSE: Conventional palpation techniques for cricothyroid membrane (CTM) identification are inaccurate and unreliable. Ultrasound plays a multi-faceted role in airway management, however there is limited...
Tue Aug 25, 2020 17:04
Related Articles Modulation of Kinases by Small Molecules for Therapeutic Management of Various Diseases - Part II. Curr Top Med Chem. 2020;20(17):1521 Authors: Bharate SB PMID: 32830621 [PubMed - in process]
Tue Aug 25, 2020 15:10
Related Articles World Chagas Disease Day and the New Road Map for Neglected Tropical Diseases. Curr Top Med Chem. 2020;20(17):1518-1520 Authors: Ferreira LLG, Andricopulo AD Abstract The first-ever World Chagas Disease Day, celebrated in April 14, 2020, is a key initiative to raise awareness of the impact of this neglected tropical disease (NTD). This landmark comes along with the first World NTD Day and the new WHO Road Map on NTDs for 2021-2030....
Tue Aug 25, 2020 15:10
Related Articles [Surgical reconstruction in laryngeal carcinoma]. HNO. 2020 Aug 24;: Authors: Arens C, Schwemmle C, Voigt-Zimmermann S Abstract Tumors of the larynx can substantially impair vocal function, breathing and also swallowing. The primary goal of reconstructive surgical treatment of laryngeal tumors is to sufficiently resect the tumor while minimizing the effects of the treatment on the voice, breathing and swallowing. In general,...
Tue Aug 25, 2020 16:36
Related Articles Surgical versus non-surgical treatment in the Obstructive Sleep Apnea-Hypopnea Syndrome. Int J Pediatr Otorhinolaryngol. 2020 Aug 12;138:110310 Authors: Martínez-Ruiz de Apodaca P, Carrasco-Llatas M, Esteller-Moré E Abstract INTRODUCTION: The treatment of choice for pediatric OSAHS is surgical. However, its etiopathogenesis is multifactorial and surgery does not always solve it. Therefore, other modalities of treatment are used....
Tue Aug 25, 2020 14:20
Related Articles Continued development of auditory ability in autism spectrum disorder children: A clinical study on click-evoked auditory brainstem response. Int J Pediatr Otorhinolaryngol. 2020 Aug 07;138:110305 Authors: Li A, Gao G, Fu T, Pang W, Zhang X, Qin Z, Ge R Abstract OBJECTIVES: The study aimed to analyze the developmental mode of auditory at the level of brainstem in preschool autistic children using click-evoked auditory brainstem...
Tue Aug 25, 2020 14:20
Related Articles Minimally invasive transoral image-guided drainage of a retropharyngeal abscess with mediastinal extension. Int J Pediatr Otorhinolaryngol. 2020 Aug 02;138:110288 Authors: Stevens C, Ladd P, Ghadersohi S, Gitomer SA Abstract Retropharyngeal abscess (RPA) in children is a serious deep neck space infection that rarely is complicated by extension into the mediastinum. RPA with mediastinal abscess requires prompt surgical management,...
Tue Aug 25, 2020 14:20
Related Articles Italian primary care paediatricians' adherence to the 2019 National Guideline for the management of acute otitis media in children: A cross-sectional study. Int J Pediatr Otorhinolaryngol. 2020 Aug 04;138:110282 Authors: Chiappini E, Motisi MA, Becherucci P, Pierattelli M, Galli L, Marchisio P Abstract INTRODUCTION: The Italian Guideline for the management of acute otitis media (AOM) in children has been recently updated. We...
Tue Aug 25, 2020 14:20
Related Articles Otological outcome in cleft lip and palate children with middle ear effusion. Int J Pediatr Otorhinolaryngol. 2020 Aug 04;138:110274 Authors: Azman A, Manuel AM Abstract OBJECTIVE: To evaluate the factors contributing to middle ear pathology, hearing and speech development among cleft palate children treated for middle ear effusion. METHOD: A prospective cross-sectional otoscopic and audiological analysis was conducted...
Tue Aug 25, 2020 14:20
Related Articles A Delphi survey based construction and validation of test for oropharyngeal dysphagia in Indian neonates. Int J Pediatr Otorhinolaryngol. 2020 Aug 11;:110306 Authors: Krishnamurthy R, Balasubramanium RK, Kamath N, Bhat KG Abstract BACKGROUND: SLPs have a crucial need to depend on comprehensive clinical swallowing assessments to determine the presence of dysphagia in neonates. A comprehensive clinical swallowing assessment that...
Tue Aug 25, 2020 14:20
Related Articles Editor's Perspective: September 2020. Int J Surg. 2020 Aug 21;: Authors: Lau JWY PMID: 32835892 [PubMed - as supplied by publisher]
Tue Aug 25, 2020 14:05
Related Articles Acrosyndactyly: Are we using the term correctly? J Plast Reconstr Aesthet Surg. 2020 Aug 13;: Authors: Bougie E, Jaloux C PMID: 32830079 [PubMed - as supplied by publisher]
Tue Aug 25, 2020 19:01
Related Articles Erratum: Measuring the Switch Cost of Smartphone Use While Walking. J Vis Exp. 2020 Aug 24;(162): Authors: Abstract An erratum was issued for: Measuring the Switch Cost of Smartphone Use While Walking. An author's name was updated. The name was corrected from: Gabrielle-Naïmé Mourra to: Gabrielle Naïmé Mourra. PMID: 32833956 [PubMed - as supplied by publisher]
Tue Aug 25, 2020 17:28
Related Articles A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft. J Vis Exp. 2020 Aug 08;(162): Authors: Blaise O, Duchesne C, Banzet S, Rousseau A, Frescaline N Abstract Trivial superficial wounds heal without complications by primary intention. Deep wounds, such as full thickness burns, heal by secondary intention and require surgical debridement and skin grafting. Successful integration of the donor graft into...
Tue Aug 25, 2020 13:26
Related Articles Isolation and Culture of Chick Ciliary Ganglion Neurons. J Vis Exp. 2020 Aug 08;(162): Authors: Costa FJ, Dias MS, Costa RO, Pedro JR, Almeida RD Abstract Chick ciliary ganglia (CG) are part of the parasympathetic nervous system and are responsible for the innervation of the muscle tissues present in the eye. This ganglion is constituted by a homogenous population of ciliary and choroidal neurons that innervate striated...
Tue Aug 25, 2020 13:26
Related Articles Laser-Capture Microdissection RNA-Sequencing for Spatial and Temporal Tissue-Specific Gene Expression Analysis in Plants. J Vis Exp. 2020 Aug 05;(162): Authors: Liew LC, Wang Y, Peirats-Llobet M, Berkowitz O, Whelan J, Lewsey MG Abstract The development of a complex multicellular organism is governed by distinct cell types that have different transcriptional profiles. To identify transcriptional regulatory networks that...
Tue Aug 25, 2020 13:26
Related Articles Precise Brain Mapping to Perform Repetitive In Vivo Imaging of Neuro-Immune Dynamics in Mice. J Vis Exp. 2020 Aug 07;(162): Authors: Bisht K, Sharma K, Eyo UB Abstract The central nervous system (CNS) is regulated by a complex interplay of neuronal, glial, stromal, and vascular cells that facilitate its proper function. Although studying these cells in isolation in vitro or together ex vivo provides useful physiological...
Tue Aug 25, 2020 13:26
Related Articles Automated Production of Human Induced Pluripotent Stem Cell-Derived Cortical and Dopaminergic Neurons with Integrated Live-Cell Monitoring. J Vis Exp. 2020 Aug 06;(162): Authors: Dhingra A, Täger J, Bressan E, Rodriguez-Nieto S, Bedi MS, Bröer S, Sadikoglou E, Fernandes N, Castillo-Lizardo M, Rizzu P, Heutink P Abstract Manual culture and differentiation protocols for human induced pluripotent stem cells (hiPSC) are difficult...
Tue Aug 25, 2020 13:26
Related Articles Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum. J Vis Exp. 2020 Aug 05;(162): Authors: Hughes PG, Hughes KE, Hughes MJ, Weaver L, Falvo LE, Bona AM, Cooper D, Hobgood C, Ahmed RA Abstract Death notification is an important and challenging aspect of Emergency Medicine. An Emergency Medicine physician must deliver bad news, often sudden and unexpected, to patients and family members...
Tue Aug 25, 2020 13:26
Related Articles Measuring Naturally Acquired Phagocytosis-Inducing Antibodies to Plasmodium falciparum Parasites by a Flow Cytometry-Based Assay. J Vis Exp. 2020 Aug 06;(162): Authors: Quintana MDP, Anabire NG, Hviid L Abstract The protocol describes how to set up and run a flow cytometry-based phagocytosis assay of Plasmodium falciparum-infected erythrocytes (IEs) opsonized by naturally acquired IgG antibodies specific for VAR2CSA. VAR2CSA...
Tue Aug 25, 2020 13:26
Related Articles Naked-Eye Detection of Rare Point Mutations in DNA. J Vis Exp. 2020 Aug 06;(162): Authors: Udayan G, Marsella A, Valentini P Abstract The protocol describes a naked-eye colorimetric test for the detection of somatic point mutations in an excess of wild type DNA. The future foreseen application of the method is the identification of rare mutations in circulating cell-free DNA from liquid biopsies, with a relevance in cancer...
Tue Aug 25, 2020 13:26
Related Articles A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties. J Vis Exp. 2020 Aug 07;(162): Authors: Calitz C, Pavlović N, Rosenquist J, Zagami C, Samanta A, Heindryckx F Abstract Hepatocellular carcinoma (HCC) is a primary liver tumor developing in the wake of chronic liver disease. Chronic liver disease and inflammation leads to a fibrotic environment...
Tue Aug 25, 2020 13:26
Related Articles Biomimetic Replication of Root Surface Microstructure using Alteration of Soft Lithography. J Vis Exp. 2020 Aug 05;(162): Authors: Kumari P, Sayas T, Kleiman M Abstract Biomimetics is the use of chemistry and material sciences to mimic biological systems, specifically biological structures, to better humankind. Recently, biomimetic surfaces mimicking the microstructure of leaf surface, were used to study the effects of...
Tue Aug 25, 2020 13:26
Related Articles An Ex Vivo Choroid Sprouting Assay of Ocular Microvascular Angiogenesis. J Vis Exp. 2020 Aug 06;(162): Authors: Tomita Y, Shao Z, Cakir B, Kotoda Y, Fu Z, Smith LEH Abstract Pathological choroidal angiogenesis, a salient feature of age-related macular degeneration, leads to vision impairment and blindness. Endothelial cell (EC) proliferation assays using human retinal microvascular endothelial cells (HRMECs) or isolated...
Tue Aug 25, 2020 13:26
Related Articles Fabrication and Characterization of Thickness Mode Piezoelectric Devices for Atomization and Acoustofluidics. J Vis Exp. 2020 Aug 05;(162): Authors: Vasan A, Connacher W, Friend J Abstract We present a technique to fabricate simple thickness mode piezoelectric devices using lithium niobate (LN). Such devices have been shown to atomize liquid more efficiently, in terms of flow rate per power input, than those that rely on...
Tue Aug 25, 2020 13:26
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