IJMS, Vol. 21, Pages 6117: Current Methods of Magnetic Resonance for Noninvasive Assessment of Molecular Aspects of Pathoetiology in Multiple Sclerosis International Journal of Molecular Sciences doi: 10.3390/ijms21176117 Authors: Petra Hnilicová Oliver Štrbák Martin Kolisek Egon Kurča Kamil Zeleňák Štefan Sivák Ema Kantorová Multiple sclerosis (MS) is an autoimmune disease with expanding axonal and neuronal degeneration in the central nervous system leading to motoric...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6116: Global Quantitative Proteomics Studies Revealed Tissue-Preferential Expression and Phosphorylation of Regulatory Proteins in Arabidopsis International Journal of Molecular Sciences doi: 10.3390/ijms21176116 Authors: Jianan Lu Ying Fu Mengyu Li Shuangshuang Wang Jingya Wang Qi Yang Juanying Ye Xumin Zhang Hong Ma Fang Chang Organogenesis in plants occurs across all stages of the life cycle. Although previous studies have identified...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6115: Molecular Pharmacology of Synthetic Cannabinoids: Delineating CB1 Receptor-Mediated Cell Signaling International Journal of Molecular Sciences doi: 10.3390/ijms21176115 Authors: Kenneth B. Walsh Haley K. Andersen Synthetic cannabinoids (SCs) are a class of new psychoactive substances (NPSs) that exhibit high affinity binding to the cannabinoid CB1 and CB2 receptors and display a pharmacological profile similar to the phytocannabinoid (-)-trans-Δ9-tetrahydrocannabinol...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6119: The Role of Endocan in Selected Kidney Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21176119 Authors: Magdalena Nalewajska Klaudia Gurazda Małgorzata Marchelek-Myśliwiec Andrzej Pawlik Violetta Dziedziejko Endocan, previously referred to as an endothelial-cell-specific molecule-1 (ESM-1) is a member of a proteoglycan family that is secreted by vascular endothelial cells of different organs, mainly lungs and kidneys. It is...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6113: Lipophagy and Lipolysis Status in Lipid Storage and Lipid Metabolism Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21176113 Authors: Anna Kloska Magdalena Węsierska Marcelina Malinowska Magdalena Gabig-Cimińska Joanna Jakóbkiewicz-Banecka This review discusses how lipophagy and cytosolic lipolysis degrade cellular lipids, as well as how these pathway ys communicate, how they affect lipid metabolism and energy homeostasis...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6111: Cell Bank Origin of MDCK Parental Cells Shapes Adaptation to Serum-Free Suspension Culture and Canine Adenoviral Vector Production International Journal of Molecular Sciences doi: 10.3390/ijms21176111 Authors: Ana Filipa Rodrigues Paulo Fernandes Tanja Laske Rute Castro Paula Marques Alves Yvonne Genzel Ana Sofia Coroadinha Phenotypic variation in cultured mammalian cell lines is known to be induced by passaging and culture conditions. Yet,...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6112: Phenotypes of Bronchopulmonary Dysplasia International Journal of Molecular Sciences doi: 10.3390/ijms21176112 Authors: Shih-Hsin Wang Po-Nien Tsao Bronchopulmonary dysplasia (BPD) is the most common chronic morbidity in preterm infants. In the absence of effective interventions, BPD is currently a major therapeutic challenge. Several risk factors are known for this multifactorial disease that results in disrupted lung development. Inflammation plays an...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6114: Diurnal Variation of Urinary Fabry Disease Biomarkers during Enzyme Replacement Therapy Cycles International Journal of Molecular Sciences doi: 10.3390/ijms21176114 Authors: Michel Boutin Pamela Lavoie Iskren Menkovic Amanda Toupin Mona Abaoui Maha Elidrissi-Elawad Marie-Françoise Arthus Carole Fortier Claudia Ménard Bruno Maranda Daniel G. Bichet Christiane Auray-Blais Fabry disease is an X-linked lysosomal storage disorder...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6109: Lamin A/C and the Immune System: One Intermediate Filament, Many Faces International Journal of Molecular Sciences doi: 10.3390/ijms21176109 Authors: Angela Saez Beatriz Herrero-Fernandez Raquel Gomez-Bris Beatriz Somovilla-Crespo Cristina Rius Jose M. Gonzalez-Granado Nuclear envelope lamin A/C proteins are a major component of the mammalian nuclear lamina, a dense fibrous protein meshwork located in the nuclear interior. Lamin A/C proteins...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6110: LAMP-2 Is Involved in Surface Expression of RANKL of Osteoblasts In Vitro
IJMS, Vol. 21, Pages 6110: LAMP-2 Is Involved in Surface Expression of RANKL of Osteoblasts In Vitro International Journal of Molecular Sciences doi: 10.3390/ijms21176110 Authors: Ineke D.C. Jansen Wikky Tigchelaar-Gutter Jolanda M. A. Hogervorst Teun J. de Vries Paul Saftig Vincent Everts Lysosome associated membrane proteins (LAMPs) are involved in several processes, among which is fusion of lysosomes with phagosomes. For the formation of multinucleated osteoclasts,...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6108: Alteration of Colonic Mucosal Permeability during Antibiotic-Induced Dysbiosis International Journal of Molecular Sciences doi: 10.3390/ijms21176108 Authors: Ying Ran Hirokazu Fukui Xin Xu Xuan Wang Nobuhiko Ebisutani Yoshiki Tanaka Ayako Maeda Yutaka Makizaki Hiroshi Ohno Takashi Kondo Tomoaki Kono Katsuyuki Tozawa Toshihiko Tomita Tadayuki Oshima Hiroto Miwa Although dysbiosis is likely to disturb the mucosal barrier...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6107: Lessons from Recent Advances in Ischemic Stroke Management and Targeting Kv2.1 for Neuroprotection International Journal of Molecular Sciences doi: 10.3390/ijms21176107 Authors: Chung-Yang Yeh Anthony J. Schulien Bradley J. Molyneaux Elias Aizenman Achieving neuroprotection in ischemic stroke patients has been a multidecade medical challenge. Numerous clinical trials were discontinued in futility and many were terminated in response to deleterious...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6106: Expression and Functionality Study of 9 Toll-Like Receptors in 33 Drug-Naïve Non-Affective First Episode Psychosis Individuals: A 3-Month Study International Journal of Molecular Sciences doi: 10.3390/ijms21176106 Authors: Maria Juncal-Ruiz Laura Riesco-Davila Javier Vazquez-Bourgon Victor Ortiz-Garcia de la Foz Jacqueline Mayoral-Van Son Rosa Ayesa-Arriola Esther Setien-Suero Juan Carlos Leza Marcos Lopez-Hoyos Benedicto Crespo-Facorro...
Tue Aug 25, 2020 03:00
IJMS, Vol. 21, Pages 6105: Extracellular Vesicles Mediate Anti-Oxidative Response—In Vitro Study in the Ocular Drainage System International Journal of Molecular Sciences doi: 10.3390/ijms21176105 Authors: Natalie Lerner Itay Chen Sofia Schreiber-Avissar Elie Beit-Yannai The importance of extracellular vesicles (EVs) as signaling mediators has been emphasized for several pathways with only limited data regarding their role as protective messages during oxidative stress (OS)....
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2751: Children’s Dental Anxiety during the COVID-19 Pandemic: Polish Experience Journal of Clinical Medicine doi: 10.3390/jcm9092751 Authors: Aneta Olszewska Piotr Rzymski Dental fear and anxiety is a significant issue that affects pediatric patients and creates challenges in oral health management. Considering that the coronavirus disease 2019 (COVID-19) pandemic, along with its associated sanitary regime, social distancing measures and nationwide quarantines,...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2749: Liquid Biopsy is Instrumental for 3PM Dimensional Solutions in Cancer Management Journal of Clinical Medicine doi: 10.3390/jcm9092749 Authors: Alena Liskova Marek Samec Lenka Koklesova Frank A. Giordano Peter Kubatka Olga Golubnitschaja One in every four deaths is due to cancer in Europe. In view of its increasing incidence, cancer became the leading cause of death and disease burden in Denmark, France, the Netherlands, and the UK. Without essential...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2748: The Role of Sense of Voice Presence and Anxiety Reduction in AVATAR Therapy
JCM, Vol. 9, Pages 2748: The Role of Sense of Voice Presence and Anxiety Reduction in AVATAR Therapy Journal of Clinical Medicine doi: 10.3390/jcm9092748 Authors: Mar Rus-Calafell Thomas Ward Xiao Chi Zhang Clementine J. Edwards Philippa Garety Tom Craig AVATAR therapy offers a unique therapeutic context that uses virtual reality technology to create a virtual embodiment of the voice-hearing experience, enabling the person to visualize their persecutory voice and engage...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2750: Risks According to the Timing and Frequency of Hypotension Episodes in Postanoxic Comatose Patients Journal of Clinical Medicine doi: 10.3390/jcm9092750 Authors: Yong Hwan Kim Jae Hoon Lee Jung In Seo Dong Hoon Lee Won Young Kim Byung Kook Lee The aim of this study was to assess the risk of unfavorable outcomes according to the timing of hypotension episodes in cardiac arrest patients. This prospectively conducted multicenter observational study...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2747: Impact of Opioid Analgesia and Inhalation Sedation Kalinox on Pain and Radial Artery Spasm during Transradial Coronary Angiography Journal of Clinical Medicine doi: 10.3390/jcm9092747 Authors: Birgy Trimaille Messas Ristorto Kayali Marchandot Cardi Hess Kibler Jesel Ohlmann Morel With respect to the transfemoral approach, transradial procedures enable a drastic reduction of bleeding events and are associated with a...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2746: Bacterial Colonization of Irrigation Fluid during Aseptic Revision Knee Arthroplasty Journal of Clinical Medicine doi: 10.3390/jcm9092746 Authors: Michael Fuchs Matthias Pumberger Hagen Hommel Carsten Perka Philipp von Roth Kathi Thiele Surgical risk factors for periprosthetic joint infection (PJI) after total knee arthroplasty (TKA) are the subjects of ongoing research. It is unclear if there are specific locations of the surgical area that might...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2745: Integrating Comorbidities and Phenotype-Based Medicine in Patient-Centered Medicine in COPD Journal of Clinical Medicine doi: 10.3390/jcm9092745 Authors: José Luis Lopez-Campos Borja Ruiz-Duque Laura Carrasco-Hernandez Candelaria Caballero-Eraso Despite recent notable innovations in the management of chronic obstructive pulmonary disease (COPD), no major advances in patient-centered medicine have been achieved. Current guidelines base their proposals...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2742: Pulmonary Rehabilitation: Time for an Upgrade Journal of Clinical Medicine doi: 10.3390/jcm9092742 Authors: Raquel Sebio-García Pulmonary rehabilitation is a notoriously known but highly underused intervention aimed to restore or improve functional capacity, symptom management and health-related quality of life among patients with chronic respiratory diseases. Since early 1980s, pulmonary rehabilitation has been acknowledged as a comprehensive intervention with...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2743: Building a Parkinson-Network–Experiences from Germany Journal of Clinical Medicine doi: 10.3390/jcm9092743 Authors: van Munster Tönges Loewenbrück Warnecke Eggers Parkinson’s disease is a complex neurodegenerative disease that can be best treated with a multi-disciplinary care approach. Building care networks has been shown as a useful tool to facilitate the integration of care services and improve outcomes for patients and care providers....
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2741: Association between Left Atrial Deformation and Brain Involvement in Patients with Anderson-Fabry Disease at Diagnosis Journal of Clinical Medicine doi: 10.3390/jcm9092741 Authors: Roberta Esposito Camilla Russo Ciro Santoro Sirio Cocozza Eleonora Riccio Regina Sorrentino Giuseppe Pontillo Federica Luciano Massimo Imbriaco Arturo Brunetti Antonio Pisani Background: Anderson-Fabry disease (AFD) can induce both central nervous system...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2744: Antimicrobial Stewardship Program, COVID-19, and Infection Control: Spread of Carbapenem-Resistant Klebsiella Pneumoniae Colonization in ICU COVID-19 Patients. What Did Not Work? Journal of Clinical Medicine doi: 10.3390/jcm9092744 Authors: Tiri Sensi Marsiliani Cantarini Priante Vernelli Martella Costantini Mariottini Andreani Bruzzone Suadoni Francucci Cirocchi Cappanera The Italian burden of disease...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2740: Targeting β2-Adrenergic Receptors Shows Therapeutical Benefits in Clear Cell Renal Cell Carcinoma from Von Hippel–Lindau Disease Journal of Clinical Medicine doi: 10.3390/jcm9092740 Authors: Virginia Albiñana Eunate Gallardo-Vara Isabel de Rojas-P Lucia Recio-Poveda Tania Aguado Ana Canto-Cano Daniel T. Aguirre Marcelo M. Serra Pilar González-Peramato Luis Martínez-Piñeiro Angel M. Cuesta Luisa Maria Botella Von Hippel–Lindau...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2739: Point-of-Care Assays Could Be Useful for Therapeutic Drug Monitoring of IBD Patients in a Proactive Strategy with Adalimumab Journal of Clinical Medicine doi: 10.3390/jcm9092739 Authors: Mohamad Cherry Dominique Dutzer Yara Nasser Anne-Emmanuelle Berger Xavier Roblin Stephane Paul The objective of the study was to evaluate whether Point-of-Care (POC) assays are equivalent to ELISAs for measuring residual trough levels of adalimumab (ADA) in a cohort...
Tue Aug 25, 2020 03:00
JCM, Vol. 9, Pages 2738: Self-Limiting versus Rotary Subjective Carious Tissue Removal: A Randomized Controlled Clinical Trial—2-Year Results Journal of Clinical Medicine doi: 10.3390/jcm9092738 Authors: Ahmed H. Ali Farah Ben Thani Federico Foschi Avijit Banerjee Francesco Mannocci Background: the aim of this study was to assess the 2-year pulp survival of deep carious lesions in teeth excavated using a self-limiting protocol in a single-blind randomized controlled clinical...
Tue Aug 25, 2020 03:00
JFMK, Vol. 5, Pages 66: The First Lactate Threshold Is a Limit for Heavy Occupational Work Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5030066 Authors: Patrick Fasching Stefan Rinnerhofer Georg Wultsch Philipp Birnbaumer Peter Hofmann Long-term heavy physical work often leads to early retirement and disability pension due to chronic overload, with a need to define upper limits. The aim of this study was to evaluate the value of the first lactate threshold...
Tue Aug 25, 2020 03:00
JoF, Vol. 6, Pages 148: Proteomic and Transcriptomic Analyses Indicate Metabolic Changes and Reduced Defense Responses in Mycorrhizal Roots of Oeceoclades maculata (Orchidaceae) Collected in Nature Journal of Fungi doi: 10.3390/jof6030148 Authors: Rafael B. S. Valadares Silvia Perotto Adriano R. Lucheta Eder C. Santos Renato M. Oliveira Marcio R. Lambais Orchids form endomycorrhizal associations with fungi mainly belonging to basidiomycetes. The molecular events taking...
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JoF, Vol. 6, Pages 146: Evaluation of Microsatellite Typing, ITS Sequencing, AFLP Fingerprinting, MALDI-TOF MS, and Fourier-Transform Infrared Spectroscopy Analysis of Candida auris Journal of Fungi doi: 10.3390/jof6030146 Authors: Mansoureh Vatanshenassan Teun Boekhout Norman Mauder Vincent Robert Thomas Maier Jacques F. Meis Judith Berman Euníce Then Markus Kostrzewa Ferry Hagen Candida auris is an emerging opportunistic yeast species causing nosocomial outbreaks...
Tue Aug 25, 2020 03:00
JoF, Vol. 6, Pages 147: Fatal Case of Fungemia by Wickerhamomyces anomalus in a Pediatric Patient Diagnosed in a Teaching Hospital from Brazil Journal of Fungi doi: 10.3390/jof6030147 Authors: Vitor Rodrigues Dutra Leonardo Francisco Silva Adriana Nazaré Miziara Oliveira Emília Freitas Beirigo Vanessa Mello Arthur Raíssa Bernardes da Silva Thatiana Bragine Ferreira Leonardo Andrade-Silva Marcos Vinícius Silva Fernanda Machado Fonseca Mario León Silva-Vergara Kennio...
Tue Aug 25, 2020 03:00
J. Imaging, Vol. 6, Pages 85: Efficient Deconvolution Architecture for Heterogeneous Systems-on-Chip
J. Imaging, Vol. 6, Pages 85: Efficient Deconvolution Architecture for Heterogeneous Systems-on-Chip Journal of Imaging doi: 10.3390/jimaging6090085 Authors: Perri Sestito Spagnolo Corsonello Today, convolutional and deconvolutional neural network models are exceptionally popular thanks to the impressive accuracies they have been proven in several computer-vision applications. To speed up the overall tasks of these neural networks, purpose-designed accelerators are highly...
Tue Aug 25, 2020 03:00
JPM, Vol. 10, Pages 101: Molecular and Cellular Mechanisms Affected in ALS Journal of Personalized Medicine doi: 10.3390/jpm10030101 Authors: Laura Le Gall Ekene Anakor Owen Connolly Udaya Geetha Vijayakumar William J. Duddy Stephanie Duguez Amyotrophic lateral sclerosis (ALS) is a terminal late-onset condition characterized by the loss of upper and lower motor neurons. Mutations in more than 30 genes are associated to the disease, but these explain only ~20% of cases....
Tue Aug 25, 2020 03:00
JPM, Vol. 10, Pages 100: Analysis of APPL1 Gene Polymorphisms in Patients with a Phenotype of Maturity Onset Diabetes of the Young Journal of Personalized Medicine doi: 10.3390/jpm10030100 Authors: Dinara E. Ivanoshchuk Elena V. Shakhtshneider Oksana D. Rymar Alla K. Ovsyannikova Svetlana V. Mikhailova Pavel S. Orlov Yuliya I. Ragino Mikhail I. Voevoda The APPL1 gene encodes a protein mediating the cross-talk between adiponectin and insulin signaling. Recently, it...
Tue Aug 25, 2020 03:00
Medicines, Vol. 7, Pages 48: Seasonal Changes in Continuous Sedentary Behavior in Community—Dwelling Japanese Adults: A Pilot Study Medicines doi: 10.3390/medicines7090048 Authors: Chiaki Uehara Nobuyuki Miyatake Shuhei Hishii Hiromi Suzuki Akihiko Katayama Background: Sedentary behavior (SB) is associated with adverse health outcomes. The aim of this study was to clarify seasonal changes in SB including continuous SB (CSB) in community-dwelling Japanese adults. Methods:...
Tue Aug 25, 2020 03:00
Membranes, Vol. 10, Pages 199: Synthesis of Cis-Cisoid or Cis-Transoid Poly(Phenyl-Acetylene)s Having One or Two Carbamate Groups as Oxygen Permeation Membrane Materials Membranes doi: 10.3390/membranes10090199 Authors: Yu Zang Yinghui Lun Masahiro Teraguchi Takashi Kaneko Hongge Jia Fengjuan Miao Xunhai Zhang Toshiki Aoki Three new phenylacetylene monomers having one or two carbamate groups were synthesized and polymerized by using (Rh(norbornadiene)Cl)2 as an initiator....
Tue Aug 25, 2020 03:00
Membranes, Vol. 10, Pages 198: Analysis of a Process for Producing Battery Grade Lithium Hydroxide by Membrane Electrodialysis Membranes doi: 10.3390/membranes10090198 Authors: Mario Grageda Alonso Gonzalez Adrian Quispe Svetlana Ushak A membrane electrodialysis process was tested for obtaining battery grade lithium hydroxide from lithium brines. Currently, in the conventional procedure, a brine with Li+ 4–6 wt% is fed to a process to form lithium carbonate and further...
Tue Aug 25, 2020 03:00
Metabolites, Vol. 10, Pages 345: Fatty Acids and Membrane Lipidomics in Oncology: A Cross-Road of Nutritional, Signaling and Metabolic Pathways Metabolites doi: 10.3390/metabo10090345 Authors: Carla Ferreri Anna Sansone Rosaria Ferreri Javier Amézaga Itziar Tueros Fatty acids are closely involved in lipid synthesis and metabolism in cancer. Their amount and composition are dependent on dietary supply and tumor microenviroment. Research in this subject highlighted the crucial...
Tue Aug 25, 2020 03:00
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