Abstract Background As infant feeding may influence allergy development, we aimed to identify groups of infants based on feeding practices and to examine their associations with respiratory health/allergy at 8 years in the PARIS birth cohort. Methods Data on breastfeeding, consumption of infant formula (regular, pre‐/probiotics, partially hydrolysed with hypoallergenic label [pHF‐HA], extensively hydrolysed [eHF], soya) and solid food introduction were collected using repeated questionnaires...
Abstract Background The association between grass pollen exposure and early markers of asthma exacerbations such as lung function changes and increase in airway inflammation is limited. We investigated the associations between short‐term grass pollen exposure and lung function and airway inflammation in a community‐based sample, and whether any such associations were modified by current asthma, current hay fever, pollen sensitization, age and other environmental factors. Methods Cross‐sectional...
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Publication date: Available online 22 August 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Hugo Charles-Messance, Kathleen A.J. Mitchelson, Elena De Marco Castro, Frederick J. Sheedy, Helen M. Roche
Publication date: Available online 21 August 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Wong Yu, Xiaoying Zhou, Mark M. Davis, Kari C. Nadeau
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Abstract Purpose of Review Over the last 13 years, the genetic etiologies have been determined for multiple conditions causing elevated serum IgE, infection susceptibilities, and variable other features. In this review, we discuss the clinical presentation, laboratory features, and genetics of these diseases caused by mutations in STAT3, DOCK8, PGM3, IL6ST, ZNF341, IL6R, IL6ST, CARD11, and CARD14, with particular focus given to...
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