Translate

Κυριακή 23 Αυγούστου 2020

 


Pharmacokinetic Study of Thirteen Ingredients after the Oral Administration of Flos Chrysanthemi Extract in Rats by UPLC-MS/MS
A rapid and reliable UPLC-MS/MS method was developed and validated for the simultaneous quantification of thirteen bioactive compounds (luteolin, cynaroside, luteolin 7-O-glucuronide, isochlorogenic acid C, chlorogenic acid, cryptochlorogenic acid, apigenin, apigenin 7-glucoside, acacetin, hyperoside, isoquercitrin, tilianin, and hesperidin) in rat plasma. The compounds were separated on an ACQUITY UPLC BEH C18 column (, 1.7 μm) with a gradient mobile phase system of acetonitrile and 0.1% (/) formic...
BioMed Research International
Fri Aug 21, 2020 18:05
Risky Sexual Behavior and Associated Factors among Adolescents Aged 15-19 Years at Governmental High Schools in Aksum Town, Tigray, Ethiopia, 2019: An Institution-Based, Cross-Sectional Study
Introduction. The impact of risky sexual practice on the general health of adolescents is enormous; little attention has been given on identification and intervention plans. Therefore, the aim of this study was to find the magnitude of risky sexual behavior and associated factors among adolescents aged 15-19 years in high schools at Aksum town, Tigray, Ethiopia. Methods. An institution-based cross-sectional study was conducted at governmental high schools of Aksum town. We recruited a total of 659...
BioMed Research International
Fri Aug 21, 2020 17:50
Response of Soybean Root to Phosphorus Deficiency under Sucrose Feeding: Insight from Morphological and Metabolome Characterizations
Phosphorus (P) is one the least available essential plant macronutrients in soils that is a major constraint on plant growth. Soybean (Glycine max L.) production is often limited due to low P availability. The better management of P deficiency requires improvement of soybean’s P use efficiency. Sugars are implicated in P starvation responses, and a complete understanding of the role of sucrose together with P in coordinating P starvation responses is missing in soybean. This study explored global...
BioMed Research International
Fri Aug 21, 2020 17:20
Effects of Occupational Hazards on Job Stress and Mental Health of Factory Workers and Miners: A Propensity Score Analysis
This study is to evaluate the effects of different occupational hazards on job stress and mental health of factory workers and miners. A total of 6120 workers from factories and mining enterprises in seven districts and one district of Urumqi were determined using the stratified cluster random sampling method. The Effort-Reward Imbalance (ERI) questionnaire and the Symptom Checklist-90 (SCL-90) were used to evaluate the effects of occupational hazard factors on job stress and mental health of workers....
BioMed Research International
Fri Aug 21, 2020 16:20
The Role of Endogenous Proteins on the Emulsification of Silicone Oils Used in Vitreoretinal Surgery
The present work is aimed at investigating the chemicophysical properties of the interface between silicone oils (SOs) used in vitreoretinal surgery and aqueous solutions, in the presence of surfactant biomolecules. Such molecules are thought to play an important role in the formation of SO emulsions in vitrectomised eyes, in which the natural vitreous body has been replaced with a SO. In particular, we have measured the interfacial tension (IT) and the interfacial dilational viscoelasticity (DV)...
BioMed Research International
Fri Aug 21, 2020 11:05
The Efficacy of Teriparatide in Improving Fracture Healing in Hip Fractures: A Systematic Review and Meta-Analysis
Background. This systematic review and meta-analysis assessed the role of teriparatide in improving hip fracture healing and function to provide a clinical guide. Methods. The systematic literature review identified randomized controlled trials (RCTs) and controlled studies evaluating teriparatide for elderly hip fractures. A meta-analysis was performed using RevMan version 5.3. Results. This study included two RCTs and four retrospective studies comprising 607 patients, with 269 and 338 patients...
BioMed Research International
Fri Aug 21, 2020 10:50
Circular RNA cir-ITCH Is a Potential Therapeutic Target for the Treatment of Castration-Resistant Prostate Cancer
cir-ITCH, a well-known tumor-suppressive circular RNA, plays a critical role in different cancers. However, its expression and functional role in prostate cancer (PCa) are unclear. Herein, we explored the potential mechanism and tumor-inhibiting role of cir-ITCH in PCa. Using reverse transcriptase polymerase chain reaction assay, we analyzed the expression of cir-ITCH in PCa and paired adjacent nontumor tissue samples resected during surgical operation, as well as in two cell lines of human PCa (LNCaP...
BioMed Research International
Fri Aug 21, 2020 09:05
The Significance of Circular RNA DDX17 in Prostate Cancer
Circular RNA DDX17 (circDDX17) has been demonstrated as a tumor suppressor in colorectal cancer. However, mechanisms underlying circDDX17 effects in cases of prostate cancer (PCa) are not well understood. Thus, herein, we determined measures of circDDX17 expression by use of the TCGA database. Expression of circDDX17 in prostate cancer-afflicted tissue samples was determined by qRT-PCR. Functionally, circDDX17 induced remarkable inhibition of cell colonizing ability, invasion, and epithelial-mesenchymal...
BioMed Research International
Fri Aug 21, 2020 09:05
AHNAK2 Is Associated with Poor Prognosis and Cell Migration in Lung Adenocarcinoma
Background. Lung adenocarcinoma (LUAD), as the main subtype of lung cancer, is one of the common causes of cancer-related deaths worldwide. The AHNAK family is correlated with cell structure and migration, cardiac calcium channel signaling, and tumor metastasis. Previous studies showed AHNAK2 could promote tumor progression and cell migration in melanoma and renal clear cell carcinoma. However, the role of AHNAK2 in LUAD remains unknown. Methods. We examined the levels of AHNAK2 in pathological specimens...
BioMed Research International
Fri Aug 21, 2020 08:20
Ultrasound Imaging Using Only Piezoelectric Organic LEDs
At North Carolina State University, researchers have performed a remarkable trick, namely producing ultrasound images using nothing but piezoelectric organic light emitting diodes. This may be a big deal, as existing ultrasound devices rely on electronics and image reconstruction algorithms to convert sonic waves captured by transducers into intuitive renderings. Avoiding these altogether may allow for much cheaper, smaller, and more capable ultrasound systems, potentially revolutionizing...
Medgadget
Fri Aug 21, 2020 19:23
BIAS: Transparent reporting of biomedical image analysis challenges
Publication date: Available online 21 August 2020Source: Medical Image AnalysisAuthor(s): Lena Maier-Hein, Annika Reinke, Michal Kozubek, Anne L. Martel, Tal Arbel, Matthias Eisenmann, Allan Hanbury, Pierre Jannin, Henning Müller, Sinan Onogur, Julio Saez-Rodriguez, Bram van Ginneken, Annette Kopp-Schneider, Bennett A. Landman
Medical Image Analysis
Sat Aug 22, 2020 13:53
PadChest: A large chest x-ray image dataset with multi-label annotated reports
Publication date: Available online 20 August 2020Source: Medical Image AnalysisAuthor(s): Aurelia Bustos, Antonio Pertusa, Jose-Maria Salinas, Maria de la Iglesia-Vayá
Medical Image Analysis
Fri Aug 21, 2020 18:03
Application of carbon dioxide to the skin and muscle oxygenation of human lower-limb muscle sites during cold water immersion
Background Cold therapy has the disadvantage of inducing vasoconstriction in arterial and venous capillaries. The effects of carbon dioxide (CO2) hot water depend mainly on not only cutaneous vasodilation but also muscle vasodilation. We examined the effects of artificial CO2 cold water immersion (CCWI) on skin oxygenation and muscle oxygenation and the immersed skin temperature. Subjects and Methods Fifteen healthy...
PeerJ Computer Science
Fri Aug 21, 2020 03:00
Chemotype classification and biomarker screening of male Eucommia ulmoides Oliv. flower core collections using UPLC-QTOF/MS-based non-targeted metabolomics
Background In the Chinese health care industry, male Eucommia ulmoides Oliv. flowers are newly approved as a raw material of functional food. Core collections have been constructed from conserved germplasm resources based on phenotypic traits and molecular markers. However, little is known about these collections’ phytochemical properties. This study explored the chemical composition of male E. ulmoides flowers, in order to provide guidance in the quality control, sustainable cultivation, and directional...
PeerJ Computer Science
Fri Aug 21, 2020 03:00
Characterization of primary cilia features reveal cell-type specific variability in in vitro models of osteogenic and chondrogenic differentiation
Primary cilia are non-motile sensory antennae present on most vertebrate cell surfaces. They serve to transduce and integrate diverse external stimuli into functional cellular responses vital for development, differentiation and homeostasis. Ciliary characteristics, such as length, structure and frequency are often tailored to distinct differentiated cell states. Primary cilia are present on a variety of skeletal cell-types and facilitate the assimilation of sensory cues to direct skeletal development...
PeerJ Computer Science
Fri Aug 21, 2020 03:00
Current and future trends in socio-economic, demographic and governance factors affecting global primate conservation
Currently, ~65% of extant primate species (ca 512 species) distributed in 91 countries in the Neotropics, mainland Africa, Madagascar, South Asia and Southeast Asia are threatened with extinction and 75% have declining populations as a result of deforestation and habitat loss resulting from increasing global market demands, and land conversion for industrial agriculture, cattle production and natural resource extraction. Other pressures that negatively impact primates are unsustainable bushmeat hunting,...
PeerJ Computer Science
Fri Aug 21, 2020 03:00
Human granulocyte-colony stimulating factor (G-CSF)/stem cell factor (SCF) fusion proteins: design, characterization and activity
Background Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are well-characterized vital hematopoietic growth factors that regulate hematopoiesis. G-CSF and SCF synergistically exhibit a stimulatory effect on hematopoietic progenitors. The combination of G-CSF and SCF has been used for mobilization of peripheral blood progenitor cells in cancer and non-cancerous conditions. To overcome challenges connected with the administration of two cytokines, we developed two fusion...
PeerJ Computer Science
Fri Aug 21, 2020 03:00
Biophysical characterization of the leukemic bone marrow vasculature reveals benefits of neo-adjuvant low-dose radiotherapy
Publication date: Available online 22 August 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Jamison Brooks, Bijender Kumar, Darren M. Zuro, Jonathon D. Raybuck, Srideshikan Sargur Madabushi, Paresh Vishwasrao, Liliana Echavarria Parra, Marcin Kortylewski, Brian Armstrong, Jerry Froelich, Susanta K. Hui
Radiation Molecular Biology.
Sun Aug 23, 2020 21:12

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Αρχειοθήκη ιστολογίου

Translate