Publication date: Available online 25 August 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Maria Alves Garcia Silva, Letícia Lopes Quirino Pantoja, Kamile Leonardi Dutra-Horstmann, José Valladares-Neto, Felipe Lucyk Wolff, André Luís Porporatti, Eliete Neves Silva Guerra, Graziela De Luca Canto
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The proximity to the patient during dental care, high generation of aerosols, and the identification of SARS-CoV-2 in saliva have suggested the oral cavity as a potential reservoir for COVID-19 transmission. Mouthwashes are widely-used solutions due to their ability to reduce the number of microorganisms in the oral cavity. Although there is still no clinical evidence that they can prevent the transmission of SARS-CoV-2, preoperative antimicrobial mouth rinses with chlorhexidine gluconate (CHX),...
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Publication date: Available online 24 August 2020Source: Archives of Oral BiologyAuthor(s): Alice Spitz, Ilana Oliveira Christovam, Guido Artemio Marañón-Vásquez, Daniele Ferreira Masterson, Daniel Adesse, Lucianne Cople Maia, Ana Maria Bolognese
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Abstract Background The current diagnostic standard for detection of high‐risk HPV in oropharyngeal squamous cell carcinoma is via a two‐stage algorithm, namely p16 immunohistochemistry followed by HPV DNA in‐situ hybridisation in p16 positive cases. This study evaluated the feasibility of automated RNA in‐situ hybridisation on a clinical platform as a single‐step alternative to the two‐stage algorithm within a routine diagnostic histopathology setting. Methods Thirty‐eight p16 positive...
Abstract Background The stroma of odontogenic cysts/tumors may confer them differential biological behavior. We aimed to investigate the immuno‐expression of stem cell markers (Nanog, SOX2, Oct4, CD34) in the stroma of odontogenic cysts and tumors. CD34 was investigated exclusively as a marker for stromal fibroblast/fibrocyte cells (CD34+SFCs). CD34+SFCs were also investigated ultrastructurally. Methods Ten cases each of primary odontogenic keratocyst (OKC), recurrent OKC, dentigerous cyst,...
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