A 71-year-old woman was referred to the clinic with extensive medication-related osteonecrosis of the jaw (MRONJ) involving the mandible. She had received 7 years of zoledronate therapy. On cone beam computed tomography, the MRONJ presented as a large sequestrum spanning from the left to the right condylar process, surrounded by thick sub-periosteal bone. The sequestrum was excised via an intraoral approach, leaving the newly formed sub-periosteal bone as a neo-mandible. The patient recovered well...
Sun Aug 23, 2020 03:00
The aim of this study was to analyse the rates of metastatic events and clinical outcomes of patients with adenoid cystic carcinoma (ACC) of the minor salivary glands and to critically evaluate the role of surgical therapy. A retrospective cohort study was designed including all patients with ACC of the oral minor salivary glands treated in the study department during the years 2010–2017. Relevant clinicopathological data were analysed to determine factors with an impact on overall survival (OS)...
Sun Aug 23, 2020 03:00
Lesions of the accessory parotid gland (APG) are rare and surgical management is generally under-discussed. The surgical approach should provide complete resection, while minimising complications and aesthetic complaints. The current study reviews recent publications on the surgical management of APG masses, and discusses the advantages, and limitations of, and our experience with, direct cheek incision. Papers on the surgical management of APG masses published in the last 10 years were systematically...
Sun Aug 23, 2020 03:00
Returning to study for a second degree to enter higher OMFS training often leaves students feeling “out in the wilderness”. Many OMFS units are keen to support these students and make use of their skills and enthusiasm by employing them. Often there are barriers to students and units working together. We have explored some of these barriers by surveying second-degree students (both medical and dental) to see what simple measures OMFS units can take to improve their support for students. From the...
Sun Aug 23, 2020 03:00
The Laster’s upper third molar and cheek retractor is a useful instrument in the armamentarium of the oral and maxillofacial surgeon or oral surgeon performing dentoalveolar surgery in the posterior maxilla. Developed by Dr Zvi Laster in the 1970s, the instrument was based on a Howarth’s nasal raspatory in combination with a cheek retractor.1 Not only does the instrument provide broad retraction of soft tissues, its reflective shape provides optimal illumination of the surgical site. It has also...
Sat Aug 22, 2020 03:00
OMFS training is perceived as a long and expensive pathway although papers have shown it compares favourably with other surgical specialties. Every OMFS clinician has a vested interest and duty continually to improve the quality of training and minimise costs, especially to trainees at junior levels. Any serious proposal to fundamentally change the format of training, must be given due consideration by all stakeholders. In 2016, a British Medical Journal article whose authors included the BAOMS President...
Sat Aug 22, 2020 03:00
Systematic reviews are studies that through a systematic search of the literature add relevant articles, providing safe data to support clinical and surgical procedures. These studies are grouped at the top of the pyramid of scientific evidence and for this reason they are increasingly sought after by researchers from all over the world, and by high-impact scientific journals.1
Sat Aug 22, 2020 03:00
Publication date: October 2020Source: Archives of Oral Biology, Volume 118Author(s): Ji Hyun Kim, Jonghwa Won, Seog Bae Oh
Sun Aug 23, 2020 21:51
Abstract With an incidence of 350.000 new cases per year, cancer of the oral cavity ranks among the 10 most common solid organ cancers. Most of these cancers are squamous cell carcinomas. Five‐year survival is about 50%. It has been shown that clear resection margins (>5 mm healthy tissue surrounding the resected tumor) have a significant positive effect on locoregional control and survival. It is not uncommon that the resection margins of oral tumors are inadequate. However, when providing the...
Thu Aug 20, 2020 15:31
Abstract Objective To investigate neuroinflammation under different periodontal status Materials and Methods Experimental periodontitis was induced by molar ligation (Lig group) or periodontal injection of lipopolysaccharide (LPS, Lps group). Periodontal status was assessed by alveolar bone resorption and periodontal inflammation. Micro‐computed tomography and hematoxylin‐eosin staining were performed to assess alveolar bone resorption and periodontal inflammation, respectively. Neuroinflammation...
Thu Aug 20, 2020 12:49
Abstract Background Despite advances in cancer diagnosis and therapeutics, the overall 5‐year survival rate of oral squamous cell carcinoma (OSCC) remains low. Tumor formation, progression, recurrence, and chemo‐resistance are associated with the presence of cancer stem cells (CSC) that show phenotypic heterogeneity, but how they influence tumor behavior remains poorly understood. We aimed to describe how two CSC phenotypes from an OSCC cell line, CD44HighESAHigh (Epi‐CSC) and CD44HighESALow...
Thu Aug 20, 2020 18:08
Abstract Background Abnormalities in the intrinsic apoptosis pathway, associated with single nucleotide variants (SNV) in Caspase (CASP) genes, alter head and neck squamous cell carcinoma (HNSCC) proliferation and progression. This prospective study aimed to evaluate whether CASP9 c.‐1339A>G and CASP3 c.‐1191A>G SNVs influence the outcome of patients with HNSCC. Two hundred sixty‐two HNSCC patients were enrolled in study. Methods DNA and RNA of peripheral blood samples were analyzed...
Thu Aug 20, 2020 18:03
Publication date: Available online 21 August 2020Source: The Journal of Prosthetic DentistryAuthor(s): Qianqian Yao, Dean Morton, George J. Eckert, Wei-Shao Lin
Fri Aug 21, 2020 15:37
You may be wondering whether it is safe to visit your UW dentist during the COVID-19 pandemic. It is definitely safe! At the UW School of Dentistry, no one has caught COVID-19 during dental care – even though thousands of patient visits have taken place in our clinics since COVID arrived. The post Is it safe to visit the dentist? appeared first on UW School of Dentistry.
Sat Aug 22, 2020 00:13
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