Related Articles Novel Albumin Nanoparticle Enhanced the Anti-Insulin-Resistant-Hepatoma Activity of Metformin. Int J Nanomedicine. 2020;15:5203-5215 Authors: Lu Z, Qi L, Lin YR, Sun L, Zhang L, Wang GC, Li JQ, Yu JM Abstract Introduction: Metformin is an ideal candidate to treat the liver tumor with insulin resistance because of its good performance in the treatment of type 2 diabetes and the advantage in cancer therapy. We aim to develop a...
Tue Aug 18, 2020 15:47
Related Articles High-Throughput Screening: today's biochemical and cell-based approaches. Drug Discov Today. 2020 Aug 12;: Authors: Blay V, Tolani B, Ho SP, Arkin MR Abstract High-throughput screening (HTS) provides starting chemical matter in the adventure of developing a new drug. In this review, we survey several HTS methods used today for hit identification, organized in two main flavors: biochemical and cell-based assays. Biochemical assays...
Tue Aug 18, 2020 15:47
Related Articles Yokukansan for treatment of preoperative anxiety and prevention of postoperative delirium in cancer patients undergoing highly invasive surgery. J-SUPPORT 1605 (ProD Study): A randomized, double-blind, placebo-controlled trial. J Pain Symptom Manage. 2020 Aug 12;: Authors: Wada S, Sadahiro R, Matsuoka YJ, Uchitomi Y, Yamaguchi T, Sato T, Shimada K, Yoshimoto S, Daiko H, Kanemitsu Y, Kawai A, Kato T, Fujimoto H, Shimizu K Abstract ...
Tue Aug 18, 2020 15:47
Related Articles Palliative Care in Dermatology: A Clinical Primer, Review of the Literature, and Needs Assessment. J Am Acad Dermatol. 2020 Aug 12;: Authors: Thompson LL, Chen ST, Lawton A, Charrow A Abstract Palliative care has been shown to improve quality of life, symptom, and caregiver burden for a range of life-limiting diseases. Palliative care use among patients with severe dermatologic disease remain relatively unexplored, but the limited...
Tue Aug 18, 2020 15:47
Related Articles Training Novice Raters to Assess Nontechnical Skills of Operating Room Teams. J Surg Educ. 2020 Aug 13;: Authors: Pradarelli JC, George E, Kavanagh J, Sonnay Y, Khoon TH, Havens JM Abstract OBJECTIVE: To our knowledge, no curricula have been described for training novice, nonclinician raters of nontechnical skills in the operating room (OR). We aimed to report the reliability of Oxford Non-Technical Skills (NOTECHS) ratings...
Tue Aug 18, 2020 15:47
Related Articles Utilization and survival outcomes of sequential, concurrent and sandwich therapies for advanced stage endometrial cancers by histology. Gynecol Oncol. 2020 Aug 13;: Authors: Ko EM, Brensinger CM, Cory L, Giuntoli RL, Haggerty AF, Latif NA, Aviles D, Martin L, Morgan MA, Lin LL Abstract OBJECTIVE: To determine the impact on overall survival (OS) of different modalities of adjuvant therapy for the treatment of stage III endometrial...
Tue Aug 18, 2020 15:47
Related Articles Implications of the United States Preventive Services Task Force Recommendations on Prostate Cancer Stage Migration. Clin Genitourin Cancer. 2020 Jul 11;: Authors: Sheng IY, Wei W, Chen YW, Gilligan TD, Barata PC, Ornstein MC, Rini BI, Garcia JA Abstract BACKGROUND: Prostate-specific antigen screening is controversial. In 2008, the United States Preventive Services Task Force recommended against screening men aged ≥ 75 years,...
Tue Aug 18, 2020 15:47
Related Articles How can we meet the support needs of LGBT cancer patients in oncology? A systematic review. Radiography (Lond). 2020 Aug 12;: Authors: Webster R, Drury-Smith H Abstract OBJECTIVES: Approximately 3.6 million people in the UK identify as lesbian, gay, bisexual and transgender (LGBT). Fear of discrimination and lack of sexual orientation and gender identity recording suggests LGBT people are invisible to health services. A systematic...
Tue Aug 18, 2020 15:47
Related Articles CircRNAs in anticancer drug resistance: recent advances and future potential. Mol Cancer. 2020 Aug 17;19(1):127 Authors: Xu T, Wang M, Jiang L, Ma L, Wan L, Chen Q, Wei C, Wang Z Abstract CircRNAs are a novel class of RNA molecules with a unique closed continuous loop structure. CircRNAs are abundant in eukaryotic cells, have unique stability and tissue specificity, and can play a biological regulatory role at various levels,...
Tue Aug 18, 2020 15:47
Related Articles Treatment of recurrent glioblastoma: state-of-the-art and future perspectives. Expert Rev Anticancer Ther. 2020 Aug 17;: Authors: Di Nunno V, Franceschi E, Tosoni A, Di Battista M, Gatto L, Lamperini C, Minichillo S, Mura A, Bartolini S, Brandes AA Abstract BACKGROUND: Almost all patients affected by glioblastoma experience recurrence of the disease. AREAS COVERED: Management of recurrent glioblastoma is a clinical...
Tue Aug 18, 2020 15:47
Related Articles A new targeted treatment for patients with a germline BRCA mutation: olaparib in pancreatic cancer. Future Oncol. 2020 Aug 17;: Authors: Verdaguer H, Acosta D, Macarulla T Abstract Pancreatic cancer has a poor prognosis. Focused efforts in the development of novel treatments of this disease have led to the approval of new combinations. Improvements in knowledge of the biology of these tumors have been made, and it is now widely...
Tue Aug 18, 2020 15:47
Related Articles Past, current and future cancer clinical research collaborations: the case of the European Organisation for Research and Treatment of Cancer. Clin Transl Sci. 2020 Aug 16;: Authors: Broes S, Saesen R, Lacombe D, Huys I Abstract While collaborations between academic institutions and industry have led to important scientific breakthroughs in the discovery stage of the pharmaceutical R&D process, the role of multi-stakeholder...
Tue Aug 18, 2020 14:10
Related Articles Current management and future perspectives of penile cancer: An updated review. Cancer Treat Rev. 2020 Aug 07;90:102087 Authors: Peyraud F, Allenet C, Gross-Goupil M, Domblides C, Lefort F, Daste A, Yacoub M, Haaser T, Ferretti L, Robert G, Ravaud A Abstract Penile cancer (PeCa) is a rare disease worldwide, accounting for less than one percent of all malignancies in men. It usually presents as a painless ulcer or lump on the...
Tue Aug 18, 2020 14:10
Related Articles [Effect of OCT4 Gene Expression Upregulation on the Expression of iPSC-related Transcription Factors in Human Bone Marrow Derived Mesenchymal Stem Cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2020 Aug;28(4):1086-1095 Authors: Guo XP, Tang YM Abstract OBJECTIVE: To explore the effect of OCT4 over-expression on the expression of induced pluripotent stem cell (iPSC)-related transcription factors (cMYC，KLF4，LIN28，NANOG and SOX2)...
Tue Aug 18, 2020 14:10
Related Articles Engaging Community-Based Cancer Physicians: Experience of the Memorial Sloan Kettering Cancer Center Cancer Alliance. J Natl Compr Canc Netw. 2019 09 01;17(9):1083-1087 Authors: Lipitz-Snyderman A, Kennington J, Hogan B, Korenstein D, Kalman L, Nair S, Yu P, Sabbatini P, Pfister D Abstract BACKGROUND: The proliferation of relationships between community health systems and academic medical centers has created a need to identify...
Tue Aug 18, 2020 14:10
Related Articles Identification of aberrantly methylated differentially expressed genes in breast cancer by integrated bioinformatics analysis. J Cell Biochem. 2019 09;120(9):16229-16243 Authors: Yi L, Luo P, Zhang J Abstract BACKGROUND: Abnormal DNA methylation has been demonstrated to drive breast cancer tumorigenesis. Thus, this study aimed to explore differentially expressed biomarkers driven by aberrant methylation in breast cancer and...
Tue Aug 18, 2020 14:10
Related Articles A Randomized Controlled Study of Integrated Smoking Cessation in a Lung Cancer Screening Program. J Thorac Oncol. 2019 09;14(9):1528-1537 Authors: Tremblay A, Taghizadeh N, Huang J, Kasowski D, MacEachern P, Burrowes P, Graham AJ, Dickinson JA, Lam SC, Yang H, Koetzler R, Tammemagi M, Taylor K, Bédard ELR Abstract INTRODUCTION: Smoking cessation activities incorporated into lung cancer screening programs have been broadly recommended,...
Tue Aug 18, 2020 14:10
Related Articles Mutations of the TERT promoter are associated with aggressiveness and recurrence/distant metastasis of papillary thyroid carcinoma. Oncol Lett. 2020 Oct;20(4):50 Authors: Liu R, Li Y, Chen W, Cong J, Zhang Z, Ma L, Chu L, Xiao H, Zhang Y, Liu Y, Xu Y, Yu Q, Yang X, Sun C Abstract Several previous studies have shown that mutations in B-Raf proto-oncogene (BRAF) and telomerase reverse transcriptase (TERT) can be used for the diagnosis...
Tue Aug 18, 2020 18:27
Related Articles Expression and clinical significance of microRNA-21, PTEN and p27 in cancer tissues of patients with non-small cell lung cancer. Oncol Lett. 2020 Oct;20(4):49 Authors: Yang L, Yang J Abstract Expression and clinical significance of micro-RNA-21, PTEN and p27 in cancer tissue of patients with non-small cell lung cancer (NSCLC) were investigated. In this study, cancer tissue and adjacent tissue specimens from 230 patients with...
Tue Aug 18, 2020 18:27
Related Articles Immune checkpoint inhibitor combination therapy for gastric cancer: Research progress. Oncol Lett. 2020 Oct;20(4):46 Authors: Song X, Qi W, Guo J, Sun L, Ding A, Zhao G, Li H, Qiu W, Lv J Abstract Gastric cancer is one of the most common types of cancer; notably, gastric cancer is one of the top five malignancies with regards to incidence and mortality rates. The symptoms of early gastric cancer are not typical, exhibiting only...
Tue Aug 18, 2020 18:27
Related Articles Current progress and prospect of immune checkpoint inhibitors in hepatocellular carcinoma. Oncol Lett. 2020 Oct;20(4):45 Authors: Zeng Z, Yang B, Liao ZY Abstract In recent years, the incidence of liver cancer has increased and is currently the sixth most common tumor and the second leading cause of cancer-associated mortality worldwide. Most cases of liver cancer are hepatocellular carcinoma (HCC). Surgery, including liver...
Tue Aug 18, 2020 18:27
Related Articles Identification of UBE2T as an independent prognostic biomarker for gallbladder cancer. Oncol Lett. 2020 Oct;20(4):44 Authors: Zhu X, Li T, Niu X, Chen L, Ge C Abstract Gallbladder cancer is the most common biliary tract malignant tumor, with unfavorable patient outcomes. The present study aimed to identify potential diagnostic or prognostic biomarkers for gallbladder cancer. To do so, differentially expressed genes in the gallbladder...
Tue Aug 18, 2020 18:27
Related Articles Analysis of clinicopathological features and prognostic factors of non-Hodgkin's intravascular large B-cell lymphoma. Oncol Lett. 2020 Oct;20(4):43 Authors: Liu Y, Ma Y, Zhou H, Zhou X, Shao J Abstract Non-Hodgkin's intravascular large B-cell lymphoma is a highly invasive extranodal lymphoma. The proliferating tumor cells invade the small vessels and capillaries of different organs. The clinical symptoms are atypical, there...
Tue Aug 18, 2020 18:27
Related Articles A multinational review: Oesophageal cancer in low to middle-income countries. Oncol Lett. 2020 Oct;20(4):42 Authors: Hull R, Mbele M, Makhafola T, Hicks C, Wang SM, Reis RM, Mehrotra R, Mkhize-Kwitshana Z, Hussain S, Kibiki G, Bates DO, Dlamini Z Abstract Oesophageal cancer (OC) is an aggressive neoplasm that manifests in the gastrointestinal tract and is the result of numerous factors that can contribute to the development...
Tue Aug 18, 2020 18:27
Related Articles Erratum: Characteristics of myeloid sarcoma in mice and patients with TET2 deficiency. Oncol Lett. 2020 Oct;20(4):41 Authors: Wang J, Miao Z, Jiang Y, Zou P, Li W, Tang X, Lv Y, Xing D, Chen S, Yang F, Xu M, Cao Z, Wang H, Zhao Z Abstract [This corrects the article DOI: 10.3892/ol.2020.11479.]. PMID: 32802163 [PubMed - as supplied by publisher]
Tue Aug 18, 2020 18:27
Related Articles HER3 protein expression as a risk factor for post-operative recurrence in patients with early-stage adenocarcinoma and adenosquamous carcinoma of the cervix. Oncol Lett. 2020 Oct;20(4):38 Authors: Mizuno T, Kojima Y, Yonemori K, Yoshida H, Sugiura Y, Ohtake Y, Okuma HS, Nishikawa T, Tanioka M, Sudo K, Shimomura A, Noguchi E, Kato T, Shimoi T, Uno M, Ishikawa M, Fujiwara Y, Ohe Y, Tamura K Abstract Patients with cervical adenocarcinoma...
Tue Aug 18, 2020 18:27
Related Articles Long non-coding RNA regulation of TRAIL in breast cancer: A tangle of non-coding threads. Oncol Lett. 2020 Oct;20(4):37 Authors: Javed Z, Khan K, Iqbal MZ, Ahmad T, Raza Q, Sadia H, Raza S, Salehi B, Sharifi-Rad J, Cho WC Abstract Breast cancer is a complex disease posing a serious threat to the female population worldwide. A complex molecular landscape and tumor heterogeneity render breast cancer cells resistant to drugs and...
Tue Aug 18, 2020 18:27
Related Articles Cluster of differentiation 19 chimeric antigen receptor T-cell therapy in pediatric acute lymphoblastic leukemia. Oncol Lett. 2020 Oct;20(4):36 Authors: Fu Z, Zhou J, Chen R, Jin Y, Ni T, Qian L, Xiao C Abstract Chimeric antigen receptor (CAR) T cells have an unprecedented positive curative effect for hematological malignances. Most notably, cluster of differentiation 19 (CD19) CAR T-cell therapy for pediatric acute lymphoblastic...
Tue Aug 18, 2020 18:27
Related Articles Ring finger protein 180 is associated with biological behavior and prognosis in patients with non-small cell lung cancer. Oncol Lett. 2020 Oct;20(4):35 Authors: Liu H, Yang P, Li X, Jia Y Abstract There are few studies on the role of ring finger protein (RNF)180 in non-small cell lung cancer (NSCLC). The present study investigated the expression of RNF180 in NSCLC and its associations with the clinical factors and prognosis...
Tue Aug 18, 2020 18:27
Related Articles Beclin-1 expression is associated with prognosis in a Bcl-2-dependent manner in non-small cell lung cancer. Oncol Lett. 2020 Oct;20(4):9 Authors: Du H, Chen L, Luo F, Chen X, Li Y, Cheng Q Abstract Beclin-1 and Bcl-2 expression abnormalities have been confirmed in different types of cancer. As important regulators of autophagy and apoptosis, respectively, these molecules serve a complex role in tumorigenesis. However, limited...
Tue Aug 18, 2020 18:27
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