Publication date: Available online 31 July 2020Source: Academic RadiologyAuthor(s): Basen Li, Anhui Xu, Yanrong Huang, Ling Peng, Kun Xiang, Qin Li, Dazhong Tang, Huijuan You, Fangqin Tan, Nan Wang
Publication date: Available online 31 July 2020Source: Academic RadiologyAuthor(s): Lucas P. Lopes Rosado, Iêda Crusoé-Rebello, Matheus Lima Oliveira, Deborah Queiroz Freitas, Frederico Sampaio Neves
Publication date: Available online 30 July 2020Source: Academic RadiologyAuthor(s): Soterios Gyftopoulos, Gina Ciavarra
Publication date: Available online 30 July 2020Source: Academic RadiologyAuthor(s): Sanaz Katal, Sean Johnston, Jennifer Johnston, Ali Gholamrezanezhad
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Abstract Purpose To compare the prognostic value of imaging biomarkers derived from a quantitative analysis of baseline 18F-FDG-PET/CT in patients with mucosal melanoma (Muc-M) or cutaneous melanoma (Cut-M) treated with immune checkpoint inhibitors (ICIs). Methods In this retrospective monocentric study, we included 56 patients with non-resectable...
Abstract Purpose Unlike the normal organ segmentation task, automatic tumor segmentation is a more challenging task because of the existence of similar visual characteristics between tumors and their surroundings, especially on computed tomography (CT) images with severe low contrast resolution, as well as the diversity and individual characteristics of data acquisition procedures and devices. Consequently, most of the recently...
Abstract Purpose PRELUDE aimed to assess use and effectiveness/safety of lanreotide autogel/depot (LAN) combined with 177Lu-DOTATOC or 177Lu-DOTATATE (LAN–peptide receptor radionuclide therapy [PRRT]) in patients with progressive neuroendocrine tumours (NETs). Methods International, non-interventional, retrospective, non-comparative analysis...
Abstract Purpose To evaluate the sensitivity and specificity of PET/CT findings in PMR and generate a diagnostic algorithm utilizing a minimum number of musculoskeletal sites. Methods Steroid-naïve patients with newly diagnosed PMR (2012 EULAR/ACR classification criteria) were prospectively recruited to undergo whole-body 18F−FDG PET/CT....
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Background. There is a pressing need for specific prognostic markers that could be used to monitor the severity of sepsis. The aims of our study were to investigate changes in the expression of different molecular forms of fibronectin in sepsis and to assess their relationship to the clinical severity and mortality of patients. Material and Methods. Forms of fibronectin: plasma (pFN), cellular (EDA-FN), FN-fibrin complexes, and fibronectin fragments were analyzed in 71 sepsis patients (survivors...
Gastric cancer (GC) is the most common malignancy of the stomach. This study was aimed at elucidating the regulatory network of circRNA-miRNA-mRNA and identifying the precise inflammation-related targets in GC. The expression profiles of GSE83521, GSE78091, and GSE33651 were obtained from the GEO database. Interactions between miRNAs and circRNAs were investigated by the Circular RNA Interactome, and targets of miRNAs were predicted with miRTarBase. Then, a circRNA/miRNA/mRNA regulatory network was...
Neuroinflammation plays a key role in the occurrence and development of neurodegenerative diseases. Microglia, the resident immune cells in the brain, have been recognized to contribute to neuroinflammation. Previous studies have shown that activated mast cells may be involved in surgery-induced neuroinflammation and neuronal apoptosis by using pharmacological methods. This study is aimed at ascertaining the exactly role of mast cells on neuroinflammation with the mast cell-deficient mice. Adult...
Aplysin is a brominated sesquiterpene with an isoprene skeleton and has biological activities. The purpose of this study is to investigate the inhibitory effect of aplysin on spontaneous pancreatic necrosis in nonobese diabetic (NOD) mice and its potential mechanisms. Results showed that NOD mice at 12 weeks of age showed obvious spontaneous pancreatic necrosis, damaged tight junctions of intestinal epithelia, and widened gaps in tight and adherens junctions. Aplysin intervention was able to alleviate...
Background/Purpose. Pars planitis (PP) is a chronic intermediate uveitis of undefined cause, although autoimmune etiology is strongly suggested. This study was undertaken to evaluate circulating pro- and anti-inflammatory lymphocyte subpopulations in patients with PP. A better understanding of immune alterations in PP may contribute to the development of an appropriate biologic treatment approach. Material and Methods. In our case-control study, samples of peripheral blood from 15 patients with pars...
Psoriasis is an inflammatory autoimmune disease characterized by cutaneous lesions in plaques. It has been proposed that the immune response has a key role in the disease progression. Particularly, the Th17 cells through IL-17 can contribute to maintain the inflammatory process. The pathogenic Th17 phenotype has been described in human diseases and associated with high severity in inflammatory experimental models. However, it is not clear if the pathogenic phenotype could be present in the skin and...
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Publication date: Available online 31 July 2020Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): F.M. González García, M.A. Peinado Montes
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Publication date: Available online 1 August 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Sergio J. Sanabria, Lisa Ruby, Jasmine Kuonen, Susanne Dettwiler, Vera Colombo, Thomas Frauenfelder, Dominik Ettlin, Marga B. Rominger
Publication date: Available online 1 August 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Sandra Sjöstrand, Maria Evertsson, Tomas Jansson
Publication date: Available online 1 August 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Kozue Saito, Soichiro Abe, Masaya Kumamoto, Yuto Uchihara, Akito Tanaka, Kazuma Sugie, Masafumi Ihara, Masatoshi Koga, Hiroshi Yamagami
Publication date: Available online 31 July 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Adeel Abbasi, Nader Azab, Mohammed Nayeemuddin, Alexandra Schick, Thomas Lopardo, Gary S. Phillips, Roland C. Merchant, Mitchell M. Levy, Michael Blaivas, Keith A. Corl
Publication date: Available online 31 July 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Chengbing Jin, Wei Yang, Lifeng Ran, Jun Zhang, Hui Zhu
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