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Related Articles Multidisciplinary patient-centered management of brain metastases and future directions. Neurooncol Adv. 2020 Jan-Dec;2(1):vdaa034 Authors: Palmer JD, Trifiletti DM, Gondi V, Chan M, Minniti G, Rusthoven CG, Schild SE, Mishra MV, Bovi J, Williams N, Lustberg M, Brown PD, Rao G, Roberge D Abstract The incidence of brain metastasis is increasing as improvements in systemic therapy lead to increased survival. This provides...
Related Articles Review of SWOG S1314: Lessons from a Randomized Phase II Study of Co-Expression Extrapolation (COXEN) with Neoadjuvant Chemotherapy for Localized, Muscle-Invasive Bladder Cancer. Bladder Cancer. 2020 Jun 11;6(2):123-129 Authors: Boxley P, Plets M, Flaig TW Abstract SWOG1314 is a randomized phase II study of co-expression extrapolation (COXEN) with neoadjuvant chemotherapy for localized, muscle-invasive bladder cancer. COXEN...
Related Articles The Latest Battles Between EGFR Monoclonal Antibodies and Resistant Tumor Cells. Front Oncol. 2020;10:1249 Authors: Cai WQ, Zeng LS, Wang LF, Wang YY, Cheng JT, Zhang Y, Han ZW, Zhou Y, Huang SL, Wang XW, Peng XC, Xiang Y, Ma Z, Cui SZ, Xin HW Abstract Epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor involved in homeostatic regulation of normal cells and carcinogenesis of epithelial malignancies. With...
Related Articles Image Based Data Mining Using Per-voxel Cox Regression. Front Oncol. 2020;10:1178 Authors: Green A, Vasquez Osorio E, Aznar MC, McWilliam A, van Herk M Abstract Image Based Data Mining (IBDM) is a novel analysis technique allowing the interrogation of large amounts of routine radiotherapy data. Using this technique, unexpected correlations have been identified between dose close to the prostate and biochemical relapse,...
Related Articles Adjuvant Therapy for Esophageal Squamous Cell Carcinoma. Korean J Thorac Cardiovasc Surg. 2020 Aug 05;53(4):168-171 Authors: Sun JM Abstract Adjuvant therapy for completely resected esophageal squamous cell carcinoma is less commonly applied in clinical practice than neoadjuvant therapy, but it plays a substantial role in improving survival for esophageal cancer patients. This article presents a concise review of the evidence...
Related Articles Protective effect of leaf extract of Abutilon indicum on DNA damage and peripheral blood lymphocytes in combating the oxidative stress. Saudi Pharm J. 2020 Aug;28(8):943-950 Authors: Wu X, Dhanasekaran S Abstract The current research explores in vitro antioxidant characteristics, radiation-induced DNA damage protection and quenching effects of the oxidative stress by the ethanolic leaf extract of Abutilon indicum (EEAI)...
The effect of neighborhood social environment on prostate cancer development in black and white men at high risk for prostate cancer. PLoS One. 2020;15(8):e0237332 Authors: Lynch SM, Handorf E, Sorice KA, Blackman E, Bealin L, Giri VN, Obeid E, Ragin C, Daly M Abstract INTRODUCTION: Neighborhood socioeconomic (nSES) factors have been implicated in prostate cancer (PCa) disparities. In line with the Precision Medicine Initiative that suggests...
Implications of immune-mediated metastatic growth on metastatic dormancy, blow-up, early detection, and treatment. J Math Biol. 2020 Aug 13;: Authors: Rhodes A, Hillen T Abstract Metastatic seeding of distant organs can occur in the very early stages of primary tumor development. Once seeded, these micrometastases may enter a dormant phase that can last decades. Curiously, the surgical removal of the primary tumor can stimulate the accelerated...
Delayed Recurrence of Chromophobe Renal Cell Carcinoma Presenting as Metastatic Duodenal Ulcer. Cureus. 2020 Jul 12;12(7):e9154 Authors: Jain N, Bharat A, Ludhwani D, Khaddour K, Weyburn T Abstract Renal cancers are one of the common causes of cancer-related morbidity and mortality worldwide. Most primary cases are localized at presentation and are treated with partial or radical nephrectomy with curative intent. However, renal cell carcinoma...
POLARIS: a prospective, multicenter, noninterventional study assessing palbociclib in hormone receptor-positive advanced breast cancer. Future Oncol. 2020 Aug 13;: Authors: Tripathy D, Blum JL, Rocque GB, Bardia A, Karuturi MS, Cappelleri JC, Liu Y, Zhang Z, Davis KL, Wang Y Abstract This report describes the rationale, purpose and design of the POLARIS study. POLARIS is an ongoing noninterventional, prospective, multicenter study. Female...
Medical oncologist perspectives on palliative care reveal physician-centered barriers to early integration. Ann Palliat Med. 2020 Aug 07;: Authors: Kruser TJ, Kruser JM, Gross JP, Moran M, Kaiser K, Szmuilowicz E, Kircher SM Abstract BACKGROUND: Early palliative care referral for patients with advanced cancer has demonstrable benefits but is underutilized. We sought to characterize medical oncologists' perceptions about palliative care...
Related Articles Preterm Brain Injury, Antenatal Triggers, and Therapeutics: Timing Is Key. Cells. 2020 Aug 10;9(8): Authors: Ophelders DRMG, Gussenhoven R, Klein L, Jellema RK, Westerlaken RJJ, Hütten MC, Vermeulen J, Wassink G, Gunn AJ, Wolfs TGAM Abstract With a worldwide incidence of 15 million cases, preterm birth is a major contributor to neonatal mortality and morbidity, and concomitant social and economic burden Preterm infants...
Related Articles Nutritional Status and Quality of Life in Hospitalised Cancer Patients Who Develop Intestinal Failure and Require Parenteral Nutrition: An Observational Study. Nutrients. 2020 Aug 07;12(8): Authors: Plyta M, Patel PS, Fragkos KC, Kumagai T, Mehta S, Rahman F, Di Caro S Abstract (1) Background: Malnutrition in cancer patients impacts quality of life (QoL) and performance status (PS). When oral/enteral nutrition is not possible...
Related Articles Modeling the Diversity of Epithelial Ovarian Cancer through Ten Novel Well Characterized Cell Lines Covering Multiple Subtypes of the Disease. Cancers (Basel). 2020 Aug 08;12(8): Authors: Sauriol A, Simeone K, Portelance L, Meunier L, Leclerc-Desaulniers K, de Ladurantaye M, Chergui M, Kendall-Dupont J, Rahimi K, Carmona E, Provencher DM, Mes-Masson AM Abstract Cancer cell lines are amongst the most important pre-clinical...
Related Articles Cancer Disparities and Health Equity: A Policy Statement From the American Society of Clinical Oncology. J Clin Oncol. 2020 Aug 12;:JCO2000642 Authors: Patel MI, Lopez AM, Blackstock W, Reeder-Hayes K, Moushey A, Phillips J, Tap W Abstract ASCO strives, through research, education, and promotion of the highest quality of patient care, to create a world where cancer is prevented and every survivor is healthy. In this pursuit,...
Related Articles Musculoskeletal interventional oncology: current and future practices. Br J Radiol. 2020 Aug 12;:20200465 Authors: Cazzato RL, Garnon J, Koch G, Dalili D, Rao PP, Weiss J, Bauones S, Auloge P, de Marini P, Gangi A Abstract Management of musculoskeletal (MSK) tumours has traditionally been delivered by surgeons and medical oncologists. However, in recent years, image-guided interventional oncology (IO) has significantly...
Related Articles Clinical efficacy, predictive biomarkers and response patterns of immunotherapy combinations for patients with cancer. Future Oncol. 2020 Aug;16(23):1659-1664 Authors: Recondo G, Mezquita L PMID: 32783513 [PubMed - in process]
Related Articles Sorafenib treatment by Child-Pugh score in Latin American patients with hepatocellular carcinoma. Future Oncol. 2020 Aug 12;: Authors: de Guevara LL, Dagher L, Arruda VM, Nakajima K, Kudo M Abstract Aim: To evaluate sorafenib treatment in Latin American patients with unresectable hepatocellular carcinoma in the real-world GIDEON study. Patients and methods: Sorafenib administration, safety and efficacy were analyzed by...
Related Articles Major Adverse Cardiovascular Events Associated With Postoperative Atrial Fibrillation After Noncardiac Surgery: A Systematic Review and Meta-Analysis. Circ Arrhythm Electrophysiol. 2020 01;13(1):e007437 Authors: AlTurki A, Marafi M, Proietti R, Cardinale D, Blackwell R, Dorian P, Bessissow A, Vieira L, Greiss I, Essebag V, Healey JS, Huynh T Abstract BACKGROUND: Postoperative atrial fibrillation (POAF) is a frequent occurrence...
Related Articles Age and Tumor Location Predict Survival in Nonmetastatic Osteosarcoma in Upper Egypt. J Pediatr Hematol Oncol. 2020 03;42(2):e66-e78 Authors: Morsy AM, Ahmed BM, Rezk KM, Ramadan IK, Aboelgheit AM, Eltyb HA, Abd Elbadee OM, El-Naggar MS Abstract AIM: The aims of this study were to assess survival outcome of pediatric patients with localized osteosarcoma of the extremities in Upper Egypt, identify factors of prognostic significance...
Related Articles A phase II clinical study of 13-deoxy, 5-iminodoxorubicin (GPX-150) with metastatic and unresectable soft tissue sarcoma. Cancer Med. 2019 06;8(6):2994-3003 Authors: Van Tine BA, Agulnik M, Olson RD, Walsh GM, Klausner A, Frank NE, Talley TT, Milhem MM Abstract BACKGROUND: 13-Deoxy, 5-iminodoxorubicin (GPX-150) is a doxorubicin (DOX) analog synthesized to reduce the formation of reactive oxygen species and the cardiotoxic...
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Related Articles Utilization of Hypofractionated Whole-Breast Radiotherapy With Concurrent Anti-Human Epidermal Growth Factor Receptor 2 (HER2) Therapy. Clin Breast Cancer. 2020 Jun 29;: Authors: Sayan M, Vergalasova I, Jhawar S, Kumar S, George M, Kowzun M, Potdevin L, Toppmeyer D, Haffty B, Ohri N Abstract INTRODUCTION: Hypofractionated radiotherapy (Hypo-RT) is now considered the standard of care for the majority of patients receiving whole-breast...
Related Articles [Phase Ⅲ randomized controlled, multicenter, prospective study of recombinant anti-HER2 humanized monoclonal antibody (Cipterbin) combined with vinorelbine in patients with HER2 positive metastatic breast cancer: the HOPES Study]. Zhonghua Yi Xue Za Zhi. 2020 Aug 11;100(30):2351-2357 Authors: Bian L, Xu BH, Di LJ, Wang T, Wang XJ, Jiao SC, Yang JL, Tong ZS, Liu J, Feng JF, Liu DG, Yu QT, Liu YP, Ma Y, Yu H, Jiang ZF Abstract ...
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Analysis of a breast cancer mathematical model by a new method to find an optimal protocol for HER2-positive cancer. Biosystems. 2020 Aug 10;:104191 Authors: Nave O, Elbaz M, Bunimovich-Mendrazitsky S Abstract Treatment of breast cancer (positive for HER2, i.e., ERBB2) is described by a mathematical model involving non-linear ordinary differential equations with a hidden hierarchy. To reveal the hierarchy of dynamical variables of the system...
Related Articles Optimizing the Duration of Trastuzumab: A Fresh Perspective. Oncology (Williston Park). 2020 Aug 12;34(8):296-301 Authors: Taylor MA, Byers KF, Meisel JL Abstract Prior to the introduction of trastuzumab, the first targeted anti-HER2 agent, in 1998, patients diagnosed with HER2-positive breast cancer felt like they were being handed a death sentence. Despite treatment with aggressive chemotherapy, their tumors recurred faster,...
Related Articles Vitamin D analogues exhibit antineoplastic activity in breast cancer patient-derived xenograft cells. J Steroid Biochem Mol Biol. 2020 Aug 09;:105735 Authors: Ferronato MJ, Nadal SM, Arenas Lahuerta EJ, Morales CB, Paolillo G, Martinez-Sabadell AA, Mascaró M, Vitale C, Fall Y, Arribas J, Facchinetti MM, Curino AC Abstract Despite advances in breast cancer (BC) treatment, its mortality remains high due to intrinsic or acquired...
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Related Articles Effect of back-up head-elevated position during drug-induced sleep endoscopy in obstructive sleep apnea patients. Sleep Breath. 2020 Aug 13;: Authors: Hsu YB, Lan MY, Huang YC, Huang TT, Lan MC Abstract PURPOSE: This study aimed to evaluate the difference of upper airway collapse between the back-up head-elevated position (a 45° upward inclination) and supine position to better elucidate the role of back-up head-elevated position...
Related Articles Evaluation of Serum and Plasma Interleukin-6 Levels in Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Meta-Regression. Front Immunol. 2020;11:1343 Authors: Imani MM, Sadeghi M, Khazaie H, Emami M, Sadeghi Bahmani D, Brand S Abstract Obstructive sleep apnea syndrome (OSAS) is considered a low-grade chronic inflammatory disease. Interleukin-6 (IL-6) is one of the most significant inflammatory markers and an excellent proxy...
Related Articles Night-to-night variability of respiratory events in obstructive sleep apnoea: a systematic review and meta-analysis. Thorax. 2020 Aug 13;: Authors: Roeder M, Bradicich M, Schwarz EI, Thiel S, Gaisl T, Held U, Kohler M Abstract BACKGROUND: It is current practice to use a single diagnostic sleep study in the diagnostic workup of obstructive sleep apnoea (OSA). However, a relevant night-to-night variability (NtNV) of respiratory...
Related Articles Pediatric Obstructive Sleep Apnea and Neurocognition. Anesthesiol Clin. 2020 Sep;38(3):693-707 Authors: Chandrakantan A, Adler AC Abstract Pediatric obstructive sleep apnea affects a large number of children and has multiple end-organ sequelae. Although many of these have been demonstrated to be reversible, the effects on some of the organ systems, including the brain, have not shown easy reversibility. Progress in this area...
Related Articles Association of snoring and body composition in (peri-post) menopausal women. BMC Womens Health. 2020 Aug 13;20(1):175 Authors: Zhou Y, Liu F, Li C, Zheng Y, Hu J, Zhou Y, Geng L, Jiang S, Teng Y, Tao M Abstract BACKGROUND: Little attention has been paid to whether snoring frequency is associated with body composition in menopausal women, particularly in China. This study objected to investigate the association between self-reported...
Related Articles [Chinese guideline for the diagnosis and treatment of childhood obstructive sleep apnea (2020)]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Aug 07;55(8):729-747 Authors: Working Group of Chinese Guideline for the Diagnosis and Treatment of Childhood OSA, Subspecialty Group of Pediatrics, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Subspecialty Group of Respiratory Diseases, Society of Pediatrics,...
Related Articles Chinese Herbs Medicine Huatan Huoxue Prescription for obstructive sleep apnea hypopnea syndrome as complementary therapy: A protocol for a systematic review and meta-analysis. Medicine (Baltimore). 2020 Jul 24;99(30):e21070 Authors: Zhou M, Liang Q, Pei Q, Xu F, Wen H Abstract OBJECTIVE: The aim of this systematic review and meta-analysis is to assess effectiveness and safety of Chinese Herbs Medicine Huatan Huoxue Prescription...
Related Articles [Application of impulse-radio ultra-wideband radar as a non-contact portable monitoring device for the diagnosis of obstructive sleep apnea]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jul;34(7):634-638 Authors: Feng C, Zhang H, Han Y, Jin X, Yang F, Zou J, Wang Y, Li Y Abstract Objective:To compare the effect of impulse-radio ultrawideband(IR-UWB) radar technology and polysomnography(PSG) in sleep assessment. Method:A...
Related Articles [Feasibility analysis of new dry electrode EEG sleep monitoring]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jul;34(7):622-625 Authors: Ye P, Li Y, Wang X, Ding X, Kang D, Li H, Wang H, Sharma A, Xu W, Han D Abstract Objective:To evaluate the accuracy of the new carbon black polyurethane dry electrode electroencephalogram and clarify the value of the new dry electrode electroencephalogram. Method:Forty-three male-adult...
Related Articles [Analysis of influencing factors of excessive daytime sleepiness in adults with different degrees of sleep-disordered breathing]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Mar;34(3):266-269 Authors: Liu H, Feng Y, Zhang Y, Chen J, Luo H, Hou J, Ren X Abstract Objective:To explore the main influencing factors of excessive daytime sleepiness(EDS) in adults with different degrees of sleep-disordered breathing(SDB), which...
Impact of obstructive sleep apnoea on cognitive function in multiple sclerosis: A longitudinal study. J Sleep Res. 2020 Aug 13;:e13159 Authors: McNicholas N, Russell A, Nolan G, Tubridy N, Hutchinson M, Garvey JF, McGuigan C Abstract Cognitive impairment (CI) and fatigue are common in people with multiple sclerosis (MS), with well-known profound effects on quality of life. Sleep disorders, including obstructive sleep apnoea (OSA), are also...
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