CARDIAC chronotropic effects of sleep-disordered breathing in patients with heart failure. J Sleep Res. 2020 Aug 13;:e13160 Authors: Pinna GD, La Rovere MT, Robbi E, Tavazzi L, Maestri R Abstract It is still not known whether the oscillation in heart rate (HR) induced by sleep-disordered breathing (SDB) in patients with heart failure entails significant chronotropic effects. We hypothesised that since cyclical changes in ventilation and arterial...
Fri Aug 14, 2020 17:20
[Diagnostic work-up in central retinal artery occlusion and ischemic optic neuropathy - what is important?] Dtsch Med Wochenschr. 2020 Aug;145(16):1112-1117 Authors: Lottspeich C, Mackert MJ, Hoffmann U, Czihal M Abstract Ischemia of the retina in central retinal artery occlusion (CRAO) and of the optic nerve in ischemic optic neuropathy (ION) are common causes of irreversible vision loss in elderly patients and require a thorough diagnostic...
Fri Aug 14, 2020 17:20
Prevalence and management of sleep disorders in the Veterans Health Administration. Sleep Med Rev. 2020 Jul 20;54:101358 Authors: Folmer RL, Smith CJ, Boudreau EA, Hickok AW, Totten AM, Kaul B, Stepnowsky CJ, Whooley MA, Sarmiento KF Abstract The prevalence of diagnosed sleep disorders among Veterans treated at Veterans Affairs (VA) medical facilities increased significantly during fiscal years (FY) 2012 through 2018. Specifically, the prevalence...
Fri Aug 14, 2020 17:20
Effects of chronic intermittent hypoxia caused by obstructive sleep apnea on lipopolysaccharide-induced acute lung injury. Exp Lung Res. 2020 Aug 13;:1-11 Authors: Kim SW, Kim IK, Yeo CD, Kang HH, Ban WH, Kwon HY, Lee SH Abstract AIM OF THE STUDY: Obstructive sleep apnea (OSA) is a common disease associated with significant morbidity and mortality. Sleep quality is an important issue; some patients with acute lung injury (ALI) have underlying...
Fri Aug 14, 2020 17:20
Identification and treatment of obstructive sleep apnea by a primary care team with a subset focus on chronic pain management. PLoS One. 2020;15(8):e0237359 Authors: Whittington K, Simpson L, Clay M, Tierney J, Harris D Abstract BACKGROUND: Patients diagnosed with obstructive sleep apnea (OSA), who also consume prescription opioids, have a greater likelihood of morbidity and mortality. This study evaluated whether a primary care team, focused...
Fri Aug 14, 2020 17:20
Finasteride Use Is Associated with Higher Odds of Obstructive Sleep Apnea: Results from the US Food and Drug Administration Adverse Events Reporting System. Skinmed. 2020;18(3):146-150 Authors: Gupta MA, Vujcic B, Gupta AK Abstract Finasteride is a 5-α reductase inhibitor indicated for the treatment of androgenetic alopecia and benign prostatic hyperplasia (BPH). Finasteride has been associated with various adverse events, such as erectile...
Fri Aug 14, 2020 17:20
Articles with impact: insights into 10 years of research with machine learning. J Appl Physiol (1985). 2020 Aug 13;: Authors: van der Zwaard S, de Leeuw AW, Meerhoff LRA, Bodine SC, Knobbe A Abstract Worldwide scientific output is growing faster and faster. Academics should not only publish much and fast, but also publish research with impact. The aim of this study is to use machine learning to investigate characteristics of articles that were...
Fri Aug 14, 2020 17:20
Variations in loop gain and arousal threshold during NREM sleep are affected by time of day over a 24 hour period in participants with obstructive sleep apnea. J Appl Physiol (1985). 2020 Aug 13;: Authors: Puri S, ElChami M, Shaheen D, Ivers B, Panza GS, Badr MS, Lin HS, Mateika JH Abstract We investigated if time of day affects loop gain and the arousal threshold during non-rapid eye movement (NREM) sleep. Eleven males with obstructive sleep...
Fri Aug 14, 2020 17:20
A network meta-analysis of different positive airway pressure interventions in obesity hypoventilation syndrome. J Sleep Res. 2020 Aug 12;:e13158 Authors: Iftikhar IH, Greer M, Wigger GW, Collop NA Abstract Continuous positive airway pressure (CPAP) and different types of non-invasive ventilation (NIV) have been studied in obesity hypoventilation syndrome such as bi-level PAP with back-up rate (BPAP-BUR), BPAP without BUR, and the new hybrid...
Fri Aug 14, 2020 17:20
Improving Nocturnal Hypoxemic Burden with Transvenous Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea. J Cardiovasc Transl Res. 2020 Aug 12;: Authors: Oldenburg O, Costanzo MR, Germany R, McKane S, Meyer TE, Fox H Abstract Nocturnal hypoxemic burden is established as a robust prognostic metric of sleep-disordered breathing (SDB) to predict mortality and treating hypoxemic burden may improve prognosis. The aim of this study...
Fri Aug 14, 2020 17:20
Bilateral Subdural Haematoma and CPAP Use: A Possible Association. Eur J Case Rep Intern Med. 2020;7(8):001602 Authors: Khater B, Kassouf V, Haddad G, Hourani R Abstract Obstructive sleep apnoea (OSA) is a common condition usually treated with continuous positive airway pressure (CPAP). No reports have linked it to an acute subdural haematoma. A 54-year-old white man who had hypertension well controlled with an angiotensin II receptor blocker,...
Fri Aug 14, 2020 17:20
Use of oximetry to screen for paediatric obstructive sleep apnoea: is one night enough and is 6 hours too much? Arch Dis Child. 2020 Aug 11;: Authors: Galway NC, Maxwell B, Shields M, O'Donoghue D Abstract INTRODUCTION: Nocturnal pulse oximetry can be used to screen for obstructive sleep apnoea (OSA) using the McGill Oximetry Score (MOS). The MOS has a time threshold for a technically adequate study of 6 hours. It has been suggested that one...
Fri Aug 14, 2020 17:20
Association between tumor necrosis factor alpha and obstructive sleep apnea in adults: a meta-analysis update. BMC Pulm Med. 2020 Aug 12;20(1):215 Authors: Cao Y, Song Y, Ning P, Zhang L, Wu S, Quan J, Li Q Abstract BACKGROUND: Tumor necrosis factor-α (TNF-α) has been reported to play a part in the development of obstructive sleep apnea (OSA) and its complications. However, the relationship between TNF-α and OSA still remains inconclusive....
Fri Aug 14, 2020 17:20
Related Articles High flow nasal cannula treatment for obstructive sleep apnea in infants and young children. Pediatr Pulmonol. 2020 Aug 12;: Authors: Ignatiuk D, Schaer B, McGinley B Abstract BACKGROUND: Continuous positive airway pressure (CPAP) is the nonsurgical treatment of choice for children with obstructive sleep apnea (OSA). However, CPAP limitations include difficulty with adherence and midface hypoplasia risk. We, therefore, sought...
Fri Aug 14, 2020 17:20
Related Articles Toll-Like Receptor-4-Mediated Inflammation is Involved in Intermittent Hypoxia-Induced Lung Injury. Lung. 2020 Aug 12;: Authors: Zou F, Su X, Pan P Abstract PURPOSE: Intermittent hypoxia (IH) is a recognized risk factor for multiple organs damage, resulting in lung injury. Its pathophysiology is still poorly understood. Toll-like receptor 4 (TLR4) signaling plays a critical role in host immune response to invading pathogen and...
Fri Aug 14, 2020 17:20
Related Articles Obstructive Sleep Apnoea in Patients Treated for Head and Neck Cancer: A Systematic Review of the Literature. Medicina (Kaunas). 2020 Aug 08;56(8): Authors: Ralli M, Campo F, Angeletti D, Allegra E, Minni A, Polimeni A, Greco A, de Vincentiis M Abstract Background and objectives: Obstructive sleep apnoea (OSA) is clinically defined by signs of daytime sleepiness and objective measures of disordered breathing during sleep. The...
Fri Aug 14, 2020 17:20
Related Articles A Tailored Motivational Messages Library for a Mobile Health Sleep Behavior Change Support System to Promote Continuous Positive Airway Pressure Use Among Patients With Obstructive Sleep Apnea: Development, Content Validation, and Testing. JMIR Mhealth Uhealth. 2020 Aug 12;8(8):e18793 Authors: Alismail S, Olfman L Abstract BACKGROUND: Continuous positive airway pressure (CPAP) therapy is the most effective treatment for obstructive...
Fri Aug 14, 2020 17:20
Related Articles Determination of risks of lower adherence to CPAP treatment before their first use by patients. J Health Psychol. 2020 Aug 12;:1359105320942862 Authors: Bros J, Poulet C, Methni JE, Deschaux C, Gandit M, Pauwels PJ, Charavel M Abstract A better understanding of Continuous Positive Airway Pressure (CPAP) adherence is a priority in improving patient care. To Identify adherence typology with a longitudinal approach, and explore...
Fri Aug 14, 2020 17:20
Related Articles Editorial on paper: The prevalence of sleep-disordered breathing in Northwest Russia - A problem worth knowing about? Chron Respir Dis. 2020 Jan-Dec;17:1479973120931863 Authors: Turnbull C PMID: 32515219 [PubMed - indexed for MEDLINE]
Fri Aug 14, 2020 17:20
Related Articles [Analysis of influencing factors of excessive daytime sleepiness in adults with different degrees of sleep-disordered breathing]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Mar;34(3):266-269 Authors: Liu H, Feng Y, Zhang Y, Chen J, Luo H, Hou J, Ren X Abstract Objective:To explore the main influencing factors of excessive daytime sleepiness（EDS） in adults with different degrees of sleep-disordered breathing（SDB）, which...
Sat Aug 15, 2020 15:57
Related Articles Misdiagnosis of Paraganglioma by 123I-mIBG Without Stable Iodine Blockade of Thyroidal Radioiodine Uptake. J Endocr Soc. 2020 Sep 01;4(9):bvaa099 Authors: Chen Cardenas SM, Duan D, Rooper LM, Santhanam P, Cooper DS, Ladenson PW Abstract Iodine-123/iodine-131 (123I/131I)-metaiodobenzylguanidine (mIBG) scan is an established tool for the localization and treatment of neuroendocrine tumors such as paragangliomas (PGL). To...
Sat Aug 15, 2020 14:33
Related Articles Selective prophylactic lateral node dissection improves the ipsilateral lateral node recurrence-free survival: A retrospective single-center cohort study. Ann Med Surg (Lond). 2020 Sep;57:190-195 Authors: Fujishima M, Miyauchi A, Ito Y, Kudo T, Kihara M, Miya A Abstract Background: Some studies have shown that prophylactic lateral neck dissection (pLND) may be beneficial for patients with papillary thyroid carcinoma (PTC);...
Sat Aug 15, 2020 14:33
Synthesis and characterization of [125I]TZ6544, a promising radioligand for investigating sphingosine-1-phosphate receptor 2. Nucl Med Biol. 2020 Jul 27;88-89:52-61 Authors: Luo Z, Liang Q, Liu H, Sumit J, Jiang H, Klein RS, Tu Z Abstract INTRODUCTION: Sphingosine-1-phosphate receptor 2 (S1PR2) activation exerts a critical role in biological abnormalities and diseases. A suitable radiotracer will advance our understanding of S1PR2 pathophysiology...
Fri Aug 14, 2020 14:26
Patient-specific anatomical models for radioiodine dosimetry in treatment of hyperthyroidism: is it necessary? Med Phys. 2020 Aug 13;: Authors: Khalili S, Miri-Hakimabad H, Hoseinian-Azghadi E Abstract PURPOSE: To investigate the necessity of patient-specific dosimetry calculations using individualized models for hyperthyroid patients treated with radioactive iodine (RAI). This treatment modality was considered to be safe and effective,...
Fri Aug 14, 2020 14:26
Sudden Development of Subcutaneous Nodules Shortly after Radioiodine Treatment for Thyroid Cancer Caused by Self-Limiting Sarcoidosis. Eur J Case Rep Intern Med. 2020;7(8):001621 Authors: Zaher W, Place S, Gombeir Y Abstract Background: Sarcoidosis is a multisystemic disease producing non-caseating granulomas. The aetiology and pathogenesis are unknown. We herewith report an atypical case of cutaneous sarcoidosis. Case presentation:...
Fri Aug 14, 2020 14:26
Adsorption of Iodine Species (I3-, I-, and IO3-) at the Nuclear Paint Monolayer-Water Interface and Its Relevance to a Nuclear Accident Scenario. J Phys Chem A. 2020 Aug 11;: Authors: Saha S, Roy S, Mathi P, Mondal JA Abstract Following a nuclear accident, radioactive iodine causes great concern to public health and safety. Organic iodide, because of its ability to escape reactor containment building and high environmental mobility, constitutes...
Fri Aug 14, 2020 14:26
Related Articles Evaluation of the pharyngeal recess with cone-beam computed tomography. Surg Radiol Anat. 2020 Aug 13;: Authors: Erdem Ş, Zengin AZ, Erdem Ş Abstract PURPOSE: To evaluate the radiological anatomy of the pharyngeal recess (PR) by gender and age. METHODS: Images of patients who underwent cone-beam computed tomography (CBCT) were analyzed retrospectively. A total of 600 PRs (140 male, 160 female) were examined. PR...
Sun Aug 16, 2020 00:43
Related Articles Investigating an Emerging Virus During a Sudden Pandemic Outbreak. Rambam Maimonides Med J. 2020 Jul 31;11(3): Authors: Sarid R Abstract At the time of writing, in July 2020, the recently emerging SARS-CoV-2 pandemic has attracted major attention to viral diseases, in particular coronaviruses. In spite of alarming molecular evidence, documentation of interspecies transmission in livestock, and the emergence of two new and relatively...
Sat Aug 15, 2020 14:21
Related Articles Treatment of COVID-19 Patients in Italy: A Physician's Experience and Insights. Rambam Maimonides Med J. 2020 Jul 31;11(3): Authors: Gilad V, Masoero G Abstract The outbreak of coronavirus disease 2019 (COVID-19) in Italy, the first Western country hit by the pandemic, seriously impacted the Italian healthcare system and social and economic environment. This perspective piece focuses on the main challenges faced by Italian hospital...
Sat Aug 15, 2020 14:21
Related Articles Comparison of Growth Patterns of COVID-19 Cases through the ARIMA and Gompertz Models. Case Studies: Austria, Switzerland, and Israel. Rambam Maimonides Med J. 2020 Jul 31;11(3): Authors: Diaz Perez FJ, Chinarro D, Otin RP, Martín RD, Diaz M, Mouhaffel AG Abstract On May 19, 2020, data confirmed that coronavirus 2019 disease (COVID-19) had spread worldwide, with more than 4.7 million infected people and more than 316,000 deaths....
Sat Aug 15, 2020 14:21
Related Articles Imaging Manifestations of Lung Injury During the COVID-19 Outbreak: What Have We Learned? Rambam Maimonides Med J. 2020 Jul 31;11(3): Authors: Ilivitzki A, Rinnot B, Glozman L Abstract Coronavirus disease-19 (COVID-19) is a pandemic infectious disease caused by a novel coronavirus. Infection can result in a wide range of clinical outcomes, from an asymptomatic condition to severe bilateral pneumonia and life-threatening conditions....
Sat Aug 15, 2020 14:21
Related Articles Israeli Position Paper: Triage Decisions for Severely Ill Patients During the COVID-19 Pandemic. Joint Commission of the Israel National Bioethics Council, the Ethics Bureau of the Israel Medical Association and Representatives from the Israeli Ministry of Health. Rambam Maimonides Med J. 2020 Jul 31;11(3): Authors: Steinberg A, Levy-Lahad E, Karni T, Zohar N, Siegal G, Sprung CL, Israel National Bioethics Council, the Ethics Bureau of the Israel...
Sat Aug 15, 2020 14:21
Related Articles The Sky Has Its Limits in COVID-19 Testing. Rambam Maimonides Med J. 2020 Jul 31;11(3): Authors: Linn S, Tzafrir S, Gueron S Abstract At the time of writing, in July 2020, the COVID-19 pandemic has already inflicted dramatic international restrictions, including airports closing and limiting international travel. It has been suggested that re-opening of airports should involve and even rely on testing travelers for COVID-19....
Sat Aug 15, 2020 14:21
Related Articles COVID-19 Compared to Other Pandemic Diseases. Rambam Maimonides Med J. 2020 Jul 31;11(3): Authors: Pitlik SD Abstract In December 2019, the first cases of a new contagious disease were diagnosed in the city of Wuhan, the capital of Hubei province in China. Within a short period of time the outbreak developed exponentially into a pandemic that infected millions of people, with a global death toll of more than 500,000 during its...
Sat Aug 15, 2020 14:21
Related Articles Technological Developments and Strategic Management for Overcoming the COVID-19 Challenge within the Hospital Setting in Israel. Rambam Maimonides Med J. 2020 Jul 31;11(3): Authors: Abbo AR, Miller A, Gazit T, Savir Y, Caspi O Abstract The coronavirus disease 2019 (COVID-19) pandemic has remarkably challenged health care organizations and societies. A key strategy for confronting the disease implications on individuals and communities...
Sat Aug 15, 2020 14:21
Related Articles Hydroxychloroquine and Coronavirus Disease 2019: A Systematic Review of a Scientific Failure. Rambam Maimonides Med J. 2020 Jul 31;11(3): Authors: Rakedzon S, Khoury Y, Rozenberg G, Neuberger A Abstract INTRODUCTION: Hydroxychloroquine (HCQ) emerged early in the course of the coronavirus disease 2019 (COVID-19) pandemic as a possible drug with potential therapeutic and prophylactic benefits. It was quickly adopted in China,...
Sat Aug 15, 2020 14:21
Related Articles Risk factors for postoperative CSF leakage after endonasal endoscopic skull base surgery: a meta-analysis and systematic review. Rhinology. 2020 Aug 12;: Authors: Kim JS, Hong SD Abstract BACKGROUND: Cerebrospinal fluid (CSF) leakage is a complication that any surgeon working in the field of skull base surgery does not wish to encounter. The surgical approach to the skull base often varies, and the various sizes and locations...
Fri Aug 14, 2020 13:14
Related Articles Treatment Strategies and Outcomes of Pediatric Esthesioneuroblastoma: A Systematic Review. Front Oncol. 2020;10:1247 Authors: Safi C, Spielman D, Otten M, Bruce JN, Feldstein N, Overdevest JB, Gudis DA Abstract Introduction: Esthesioneuroblastoma, also known as olfactory neuroblastoma, is a small round blue cell tumor of nasal neuroepithelium first described in 1924. Though this tumor is especially rare in the pediatric population...
Sat Aug 15, 2020 14:07
Related Articles Improving Function in Cavernous Sinus Meningiomas: A Modern Treatment Algorithm. Front Neurol. 2020;11:652 Authors: Beer-Furlan A, Priddy BH, Jamshidi AO, Shaikhouni A, Prevedello LM, Ditzel Filho L, Otto BA, Carrau RL, Prevedello DM Abstract Background: The efficacy and safety of radiosurgery led to paradigm shift in the management of cavernous sinus meningiomas. Nevertheless, patients are still significantly affected by cranial...
Sat Aug 15, 2020 14:07
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