Related Articles Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome. Front Cell Dev Biol. 2020;8:654 Authors: Martín-Suárez S, Abiega O, Ricobaraza A, Hernandez-Alcoceba R, Encinas JM Abstract Hippocampal neurogenesis, the process by which neural stem cells (NSCs) continuously generate new neurons in the dentate gyrus (DG) of most mammals including humans, is chiefly regulated by neuronal activity. Thus, severe...
Sat Aug 15, 2020 14:01
Related Articles Can REM Sleep Localize the Epileptogenic Zone? A Systematic Review and Analysis. Front Neurol. 2020;11:584 Authors: McLeod GA, Ghassemi A, Ng MC Abstract Epilepsy is a common and debilitating neurological disease. When medication cannot control seizures in up to 40% of cases, surgical resection of epileptogenic tissue is a clinically and cost- effective therapy to achieve seizure freedom. To simultaneously resect minimal yet...
Sat Aug 15, 2020 14:01
Related Articles Decanoic Acid and Not Octanoic Acid Stimulates Fatty Acid Synthesis in U87MG Glioblastoma Cells: A Metabolomics Study. Front Neurosci. 2020;14:783 Authors: Damiano F, De Benedetto GE, Longo S, Giannotti L, Fico D, Siculella L, Giudetti AM Abstract Medium-chain fatty acids (MCFA) are dietary components with a chain length ranging from 6 to 12 carbon atoms. MCFA can cross the blood-brain barrier and in the brain can be oxidized...
Sat Aug 15, 2020 14:01
Related Articles Valeriana officinalis Counteracts Rotenone Effects on Spreading Depression in the Rat Brain in vivo and Protects Against Rotenone Cytotoxicity Toward Rat Glioma C6 Cells in vitro. Front Neurosci. 2020;14:759 Authors: Amaral de Brito AP, Galvão de Melo IMDS, El-Bachá RS, Guedes RCA Abstract Astrocytes can protect neurons against oxidative stress and excitability-dependent disorders, such as epilepsy. Valeriana officinalis has...
Sat Aug 15, 2020 14:01
Related Articles Non-pharmacological Interventions for Intractable Epilepsy. Saudi Pharm J. 2020 Aug;28(8):951-962 Authors: Alqahtani F, Imran I, Pervaiz H, Ashraf W, Perveen N, Rasool MF, Alasmari AF, Alharbi M, Samad N, Alqarni SA, Al-Rejaie SS, Alanazi MM Abstract In 30% of epileptic individuals, intractable epilepsy represents a problem for the management of seizures and severely affects the patient's quality of life due to pharmacoresistance...
Sat Aug 15, 2020 14:01
Related Articles Properties of beta oscillations in Dup15q syndrome. J Neurodev Disord. 2020 Aug 13;12(1):22 Authors: Saravanapandian V, Frohlich J, Hipp JF, Hyde C, Scheffler AW, Golshani P, Cook EH, Reiter LT, Senturk D, Jeste SS Abstract BACKGROUND: Duplications of 15q11.2-q13.1 (Dup15q syndrome) are highly penetrant for autism, intellectual disability, hypotonia, and epilepsy. The 15q region harbors genes critical for brain development,...
Sat Aug 15, 2020 14:01
Related Articles Reply. AJNR Am J Neuroradiol. 2020 06;41(6):E47-E48 Authors: Foesleitner O, Nenning KH, Bartha-Doering L, Baumgartner C, Pataraia E, Moser D, Schwarz M, Schmidbauer V, Hainfellner JA, Czech T, Dorfer C, Langs G, Prayer D, Bonelli S, Kasprian G PMID: 32439648 [PubMed - indexed for MEDLINE]
Sat Aug 15, 2020 14:01
Related Articles Paediatric status epilepticus: finally, some evidence-based treatment guidance, but still a long way to go. Lancet Child Adolesc Health. 2020 05;4(5):351-352 Authors: Lagae L PMID: 32336347 [PubMed - indexed for MEDLINE]
Sat Aug 15, 2020 14:01
[Dynamics of epileptiform activity, efficacy and tolerability of valproic acid in adults and adolescents with newly-diagnosed epilepsy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(7):35-43 Authors: Karlov VA, Kozhokaru AB, Vlasov PN, Pushkar TN, Orlova AS Abstract OBJECTIVE: To evaluate the changes of epileptiform activity index (EAI) as a measure of the efficacy and tolerability of treatment with valproic acid (VA) in patients with newly-diagnosed...
Fri Aug 14, 2020 13:44
[Oxidative stress in focal symptomatic and cryptogenic epilepsy in young patients]. Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(7):17-22 Authors: Fedin AI, Starykh EV, Baranova OA, Chekanov AV, Torshin DV, Mikhailova EV Abstract OBJECTIVE: To study oxidative stress in young patients with focal symptomatic and cryptogenic epilepsy and after the new-onset epileptic seizures. MATERIAL AND METHODS: Patients, aged from 19 to 44 years,...
Fri Aug 14, 2020 13:44
[Children with parainfluenza pneumonia complicated with rhabdomyolysis syndrome and acute kidney injury: a case report and literature review]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2020 Jul;32(7):861-863 Authors: Sun X, Xu Q, He L, Huang T, Liu Y Abstract OBJECTIVE: To investigate the diagnosis and treatment of children with parainfluenza pneumonia complicated with rhabdomyolysis syndrome and acute kidney injury (AKI). METHODS: The...
Fri Aug 14, 2020 13:44
The Imidazodiazepine Anticonvulsant, KRM-II-81, Produces Novel, Non-diazepam-like Antiseizure Effects. ACS Chem Neurosci. 2020 Jul 30;: Authors: Knutson DE, Smith JL, Ping X, Jin X, Golani LK, Li G, Tiruveedhula VVNPB, Rashid F, Mian MY, Jahan R, Sharmin D, Cerne R, Cook JM, Witkin JM Abstract The need for improved medications for the treatment of epilepsy and chronic pain is essential. Epileptic patients typically take multiple antiseizure...
Fri Aug 14, 2020 13:44
Related Articles Postinjury weight rather than cognitive or behavioral impairment predicts development of posttraumatic epilepsy after lateral fluid-percussion injury in rats. Epilepsia. 2020 Aug 12;: Authors: Lapinlampi N, Andrade P, Paananen T, Hämäläinen E, Ekolle Ndode-Ekane X, Puhakka N, Pitkänen A Abstract OBJECTIVE: To identify postinjury physiologic, behavioral, and cognitive biomarkers for posttraumatic epilepsy to enrich study populations...
Fri Aug 14, 2020 13:44
Related Articles Circulating MicroRNAs from Serum Exosomes May Serve as a Putative Biomarker in the Diagnosis and Treatment of Patients with Focal Cortical Dysplasia. Cells. 2020 Aug 10;9(8): Authors: Chen SD, Pan HY, Huang JB, Liu XP, Li JH, Ho CJ, Tsai MH, Yang JL, Chen SF, Chen NC, Chuang YC Abstract Focal cortical dysplasia (FCD) is a congenital malformation of cortical development where the cortical neurons located in the brain area fail...
Fri Aug 14, 2020 13:44
Related Articles An Open Pilot Study of the Effect and Tolerability of Add-On Multivitamin Therapy in Patients with Intractable Focal Epilepsy. Nutrients. 2020 Aug 07;12(8): Authors: Chang HH, Sung PS, Liao WC, Chang AYW, Hsiao YH, Fu TF, Huang CY, Huang CW Abstract Observational studies have investigated the potential modulatory effect of neuronal excitability by vitamins in epilepsy. We aimed to investigate whether the addition of multivitamin...
Fri Aug 14, 2020 13:44
Related Articles Robotic Stereotactic Assistance (ROSA) for Pediatric Epilepsy: A Single-Center Experience of 23 Consecutive Cases. Children (Basel). 2020 Aug 07;7(8): Authors: Nelson JH, Brackett SL, Oluigbo CO, Reddy SK Abstract Robotic assisted neurosurgery has become increasingly utilized for its high degree of precision and minimally invasive approach. Robotic stereotactic assistance (ROSA®) for neurosurgery has been infrequently reported...
Fri Aug 14, 2020 13:44
Related Articles Mechanism of Action of Ketogenic Diet Treatment: Impact of Decanoic Acid and Beta-Hydroxybutyrate on Sirtuins and Energy Metabolism in Hippocampal Murine Neurons. Nutrients. 2020 Aug 08;12(8): Authors: Dabke P, Das AM Abstract The ketogenic diet (KD), a high-lipid and low-carbohydrate diet, has been used in the treatment of epilepsy, neurodegenerative disorders, inborn errors of metabolism and cancer; however, the exact mechanism/s...
Fri Aug 14, 2020 13:44
Related Articles Effect of aliskiren on the anticonvulsant activity of antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice. Epilepsy Res. 2020 Jul 30;167:106435 Authors: Łukawski K, Raszewski G, Czuczwar SJ Abstract Drug-drug interactions should be considered during the pharmacological treatment in patients with epilepsy and coexisting hypertension. Experimental studies in rodents showed that antihypertensive drugs which block...
Fri Aug 14, 2020 13:44
Related Articles Sleep modulates effective connectivity: A study using intracranial stimulation and recording. Clin Neurophysiol. 2020 02;131(2):529-541 Authors: Arbune AA, Popa I, Mindruta I, Beniczky S, Donos C, Daneasa A, Mălîia MD, Băjenaru OA, Ciurea J, Barborica A Abstract OBJECTIVE: Sleep is an active process with an important role in memory. Epilepsy patients often display a disturbed sleep architecture, with consequences on cognition....
Fri Aug 14, 2020 13:44
Related Articles Use of antiepileptic drugs and risk of skin cancer: A nationwide case-control study. J Am Acad Dermatol. 2020 Feb;82(2):326-335 Authors: Kristensen KB, Pedersen SA, Schmidt SAJ, Pottegård A Abstract BACKGROUND: Several antiepileptic drugs are photosensitizing; however, it is not known whether this confers an increased risk of skin cancer. OBJECTIVE: To examine the association between common antiepileptic drugs and...
Fri Aug 14, 2020 13:44
Sex-based differences in outcomes of patients with HPV-positive versus HPV-negative oropharyngeal carcinoma: a population-based study. Expert Rev Anticancer Ther. 2020 Aug 13;: Authors: Abdel-Rahman O Abstract OBJECTIVES: Prior studies have suggested that female sex is predictive of poor outcomes among patients with oropharyngeal carcinoma. The current study aims to elucidate whether this observation applies to both HPV-positive and HPV-negative...
Fri Aug 14, 2020 13:58
Related Articles The Redox Biology of Excitotoxic Processes: The NMDA Receptor, TOPA Quinone, and the Oxidative Liberation of Intracellular Zinc. Front Neurosci. 2020;14:778 Authors: Aizenman E, Loring RH, Reynolds IJ, Rosenberg PA Abstract This special issue of Frontiers in Neuroscience-Neurodegeneration celebrates the 50th anniversary of John Olney's seminal work introducing the concept of excitotoxicity as a mechanism for neuronal cell death....
Sat Aug 15, 2020 13:37
Related Articles A Multidimensional, Multisensory and Comprehensive Rehabilitation Intervention to Improve Spatial Functioning in the Visually Impaired Child: A Community Case Study. Front Neurosci. 2020;14:768 Authors: Morelli F, Aprile G, Cappagli G, Luparia A, Decortes F, Gori M, Signorini S Abstract Congenital visual impairment may have a negative impact on spatial abilities and result in severe delays in perceptual, social, motor, and cognitive...
Sat Aug 15, 2020 13:37
Related Articles Evaluation of Biased and Balanced Salvinorin A Analogs in Preclinical Models of Pain. Front Neurosci. 2020;14:765 Authors: Paton KF, Biggerstaff A, Kaska S, Crowley RS, La Flamme AC, Prisinzano TE, Kivell BM Abstract In the search for safer, non-addictive analgesics, kappa opioid receptor (KOPr) agonists are a potential target, as unlike mu-opioid analgesics, they do not have abuse potential. Salvinorin A (SalA) is a potent...
Sat Aug 15, 2020 13:37
Related Articles Thrombin, a Mediator of Coagulation, Inflammation, and Neurotoxicity at the Neurovascular Interface: Implications for Alzheimer's Disease. Front Neurosci. 2020;14:762 Authors: Iannucci J, Renehan W, Grammas P Abstract The societal burden of Alzheimer's disease (AD) is staggering, with current estimates suggesting that 50 million people world-wide have AD. Identification of new therapeutic targets is a critical barrier to the...
Sat Aug 15, 2020 13:37
Related Articles The Effect of Music Intervention on Attention in Children: Experimental Evidence. Front Neurosci. 2020;14:757 Authors: Kasuya-Ueba Y, Zhao S, Toichi M Abstract Although music has been utilized as a therapeutic tool for children with cognitive impairments, how it improves children's cognitive function remains poorly understood. As a first step toward understanding music's effectiveness and as a means of assessing cognitive function...
Sat Aug 15, 2020 13:37
Related Articles Autodidacticism and Music: Do Self-Taught Musicians Exhibit the Same Auditory Processing Advantages as Formally Trained Musicians? Front Neurosci. 2020;14:752 Authors: Zendel BR, Alexander EJ Abstract Multiple studies have demonstrated that musicians have enhanced auditory processing abilities compared to non-musicians. In these studies, musicians are usually defined as having received some sort of formal music training. One...
Sat Aug 15, 2020 13:37
Related Articles The Effects of Transcranial Electrical Stimulation on Human Motor Functions: A Comprehensive Review of Functional Neuroimaging Studies. Front Neurosci. 2020;14:744 Authors: Gao Y, Cavuoto L, Schwaitzberg S, Norfleet JE, Intes X, De S Abstract Transcranial electrical stimulation (tES) is a promising tool to enhance human motor skills. However, the underlying physiological mechanisms are not fully understood. On the other hand,...
Sat Aug 15, 2020 13:37
Related Articles Implementing Mobile HRV Biofeedback as Adjunctive Therapy During Inpatient Psychiatric Rehabilitation Facilitates Recovery of Depressive Symptoms and Enhances Autonomic Functioning Short-Term: A 1-Year Pre-Post-intervention Follow-Up Pilot Study. Front Neurosci. 2020;14:738 Authors: Tatschl JM, Hochfellner SM, Schwerdtfeger AR Abstract Objective: New treatment options for depression are warranted, due to high recurrence rates....
Sat Aug 15, 2020 13:37
Related Articles Test-Retest-Reliability of Video-Oculography During Free Visual Exploration in Right-Hemispheric Stroke Patients With Neglect. Front Neurosci. 2020;14:731 Authors: Kaufmann BC, Cazzoli D, Müri RM, Nef T, Nyffeler T Abstract The Mean gaze position during free visual exploration (FVE) is a sensitive tool to detect neglect in patients after a right-hemispheric stroke. Here we investigated the test-retest-reliability of mean gaze...
Sat Aug 15, 2020 13:37
Related Articles Development of a Fully Implantable Stimulator for Deep Brain Stimulation in Mice. Front Neurosci. 2020;14:726 Authors: Fleischer M, Endres H, Sendtner M, Volkmann J Abstract Introduction: Deep brain stimulation is an established method for the treatment of neurological and psychiatric disorders. To elicit the underlying mechanisms and explore new stimulation targets, rodent models are necessary. Cable bound external stimulation...
Sat Aug 15, 2020 13:37
Related Articles Performance on the Robotics On-Board Trainer (ROBoT-r) Spaceflight Simulation During Acute Sleep Deprivation. Front Neurosci. 2020;14:697 Authors: Wong L, Pradhan S, Karasinski J, Hu C, Strangman G, Ivkovic V, Arsintescu L, Flynn-Evans E Abstract Exploration of deep space poses many challenges. Mission support personnel will not be immediately available to assist crewmembers performing complex operations on future long-duration...
Sat Aug 15, 2020 13:37
Related Articles Automatic Reconstruction of Mitochondria and Endoplasmic Reticulum in Electron Microscopy Volumes by Deep Learning. Front Neurosci. 2020;14:599 Authors: Liu J, Li L, Yang Y, Hong B, Chen X, Xie Q, Han H Abstract Together, mitochondria and the endoplasmic reticulum (ER) occupy more than 20% of a cell's volume, and morphological abnormality may lead to cellular function disorders. With the rapid development of large-scale electron...
Sat Aug 15, 2020 13:37
Related Articles Prognostic value of MRI-determined cervical lymph node size in nasopharyngeal carcinoma. Cancer Med. 2020 Aug 13;: Authors: Huang CL, Chen Y, Guo R, Mao YP, Xu C, Tian L, Liu LZ, Lin AH, Sun Y, Ma J, Tang LL Abstract OBJECTIVES: To investigate the prognostic value of magnetic resonance imaging (MRI)-determined cervical lymph node (CLN) size in nasopharyngeal carcinoma (NPC). METHODS: We retrospectively reviewed...
Sat Aug 15, 2020 13:30
Related Articles Evaluation of the modified Pittsburgh classification for predicting the disease-free survival outcome of squamous cell carcinoma of the external auditory canal. Head Neck. 2020 Aug 13;: Authors: Nabuurs CH, Kievit W, Labbé N, Leemans CR, Smit CFGM, van den Brekel MWM, Pauw RJ, van der Laan BFAM, Jansen JC, Lacko M, Braunius WW, Morita S, Wierzbicka M, Matoba T, Hanai N, Takes RP, Kunst HPM Abstract BACKGROUND: Squamous...
Sat Aug 15, 2020 13:30
Related Articles Prognostic Significances of NEDD-9 and FOXL-1 Expression in Intestinal Type Gastric Carcinoma: an Immunohistochemical Study. J Gastrointest Cancer. 2020 Aug 14;: Authors: Elaidy NF, Harb OA, Mohamed AM, Hemeda R, Taha HF, Samir A, Elsayed AM, Osman G, Hendawy EIE Abstract BACKGROUND: Gastric cancer (GC) is mostly diagnosed at advanced stage, so prognosis is poor. Therefore, it is necessary to understand the molecular mechanism...
Sat Aug 15, 2020 13:30
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