Related Articles Risk Factors for Readmission After Short-Hospital-Stay Laparoscopic Appendectomy. World J Surg. 2020 Aug 13;: Authors: Angeramo CA, Dreifuss NH, Olivero AA, Sadava EE, Schlottmann F Abstract BACKGROUND: Single-day discharge is a common practice among patients undergoing laparoscopic appendectomy (LA). We aimed to determine risk factors associated with readmission in patients with short hospital stay after LA. METHODS:...
Endoscopic versus Conventional Thyroid Surgery: A Comparison of Quality of Life, Cosmetic Outcomes and Overall Patient Satisfaction with Treatment. World J Surg. 2020 Aug 13;: Authors: Johri G, Chand G, Mishra A, Mayilvaganan S, Agarwal G, Agarwal A, Mishra SK Abstract BACKGROUND: Our aim was to investigate whether the surgical approach, i.e. endoscopic (ET) versus conventional/open thyroidectomy (ConT), contributes towards the improvement...
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Navigated Ultrasonic Osteotomy to Aid in En Bloc Chordoma Resection via Spondylectomy. World Neurosurg. 2020 Aug 10;: Authors: Detchou DK, Dimentberg R, Vaughan KA, Kolster R, Braslow BM, Malhotra NR Abstract Chordomas are rare, locally malignant tumors derived from remnants of the notochord that can manifest anywhere in the spine or base of the skull. Surgical treatment for chordomas of the lumbar spine often fails to achieve successful en...
Association between Physician Industry Payments and Cost of Anterior Cervical Discectomy and Fusion in Medicare Beneficiaries. World Neurosurg. 2020 Aug 10;: Authors: Liu C, Ahmed K, Chen CL, Dudley RA, Gonzales R, Orrico K, Yerneni K, Stienen MN, Veeravagu A, Desai A, Park J, Ratliff JK, Zygourakis CC Abstract BACKGROUND: Neurosurgical spine specialists receive considerable amounts of industry support which may impact the cost of care. The...
Chiari malformations type I without basilar invagination in adults: a morphometric and volumetric analysis. World Neurosurg. 2020 Aug 10;: Authors: Wang S, Huang Z, Xu R, Liao Z, Yan Y, Tang W, Xia Y Abstract BACKGROUND: Chiari malformation type I (CMI) cases are frequently associated with basilar invagination (BI), which complicates the understanding of the pathology of CMI. We specifically evaluated the morphometric and volumetric alterations...
Acute postoperative bilateral vocal fold paralysis after posterior spinal correction for dropped head syndrome: A case report. World Neurosurg. 2020 Aug 10;: Authors: Thormodsson HS, Ntouniadakis E, Holy M, Sigmundsson FG Abstract BACKGROUND: Acute bilateral vocal fold paralysis is a life-threatening complication in spinal surgery but it is almost exclusively anticipated with anterior approaches. Bilateral vocal fold paralysis after posterior...
Contralateral transfalcine approach to deep parasagittal AVMs - technical note. World Neurosurg. 2020 Aug 10;: Authors: Peto I, Nouri M, Katz J, Woo H, Dehdashti AR Abstract BACKGROUND: Resection of deep medial frontal and parietal arterio-venous malformations (AVM) is often challenging due to a tangential angle of attack, deep and narrow working corridor. Adequate visualization of the AVM and its feeding arteries without brain retraction is...
Cervical disc arthroplasty migration following mechanical intubation: a case presentation and review of literature. World Neurosurg. 2020 Aug 10;: Authors: Khan MQ, Prim MD, Alexopoulos G, Kemp JM, Mercier PJ Abstract BACKGROUND: Cervical arthroplasty has established itself as a safe and efficacious alternative to fusion in management of symptomatic cervical degenerative disease. Recent literature has indicated a trend toward decreased risk...
Vegetation of ventriculoatrial shunt managed via multidisciplinary surgical approach. World Neurosurg. 2020 Aug 10;: Authors: Entezami P, Devejian NS, Rubino S, Smith N, Savery P, Crnkovic A, Adamo MA Abstract INTRODUCTION: The popularity of the ventriculoatrial shunt as a means for cerebrospinal fluid diversion was temporally limited, overcome by the success of the peritoneum as a site for distal drainage. Nevertheless, it remains an important...
Frameless Stereotactic Biopsy with DTI-based tractography integration: how to adjust the trajectory - a case series. World Neurosurg. 2020 Aug 10;: Authors: Bertuccio A, Elia A, Robba C, Scaglione G, Longo GP, Sgubin D, Vitali M, Barbanera A PMID: 32791224 [PubMed - as supplied by publisher]
Intramedullary hemorrhage caused by lumbosacral epidural arteriovenous fistula with dual retrograde perimedullary venous draining routes: A case report and review of the literature. World Neurosurg. 2020 Aug 10;: Authors: Iampreechakul P, Liengudom A, Wangtanaphat K, Narischat P, Lertbutsayanukul P, Siriwimonmas S PMID: 32791223 [PubMed - as supplied by publisher]
Economic Impact of COVID-19 on a High Volume Academic Neurosurgical Practice. World Neurosurg. 2020 Aug 10;: Authors: Sivakanthan S, Pan J, Kim L, Ellenbogen R, Saigal R Abstract INTRODUCTION: Coronavirus-19 (COVID-19) is a novel disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that rapidly spread around the globe. The dramatic increase in the number of cases and deaths have placed tremendous strain on healthcare...
Long-term Epilepsy Associated Tumors (LEATs): A Single-centre, Retrospective Series and Review of Literature on Factors Affecting the Seizure Outcome. World Neurosurg. 2020 Aug 10;: Authors: Mehrotra A, Singh S, Kanjilal S, Kumar A, Pal L, Mathur V, Paliwal VK, Sardhara J, Singh Bhaisora K, Kumar Srivastava A, Jaiswal AK, Behari S Abstract BACKGROUND: Tumors presenting with drug-resistant seizures are termed as LEATs. LEATs are more common...
Suprapedicular retrocorporeal technique of transforaminal full-endoscopic lumbar discectomy for highly downward-migrated disc herniation. World Neurosurg. 2020 Aug 10;: Authors: Chen CM, Lin GX, Sharma S, Kim HS, Sun LW, Wu HH, Chang KS, Chen YC Abstract OBJECTIVE: Anatomical barriers (e.g., pedicles, narrow foramina) hinder direct access to, and removal of, disc fragments that have migrated far downward. Based on the transforaminal full-endoscopic...
TARGETED MUSCLE REINNERVATION AND OSSEOINTEGRATION FOR PAIN RELIEF AND PROSTHETIC ARM CONTROL IN A WOMAN WITH BILATERAL PROXIMAL UPPER-LIMB AMPUTATION: CASE REPORT. World Neurosurg. 2020 Aug 10;: Authors: Vincitorio F, Staffa G, Aszmann OC, Fontana M, Brånemark R, Randi P, Macchiavelli T, Cutti AG Abstract BACKGROUND: Bilateral proximal upper limb loss is a dramatic life-change event. Replacement of the lost functions with prosthetic arms including...
An aneurysm at the origin of a duplicated middle cerebral artery treated by stent-assisted coiling using the "wrapped candy" LVIS technique: A technical case report. World Neurosurg. 2020 Aug 10;: Authors: Imahori T, Mizobe T, Fujinaka T, Miura S, Sugihara M, Aihara H, Kohmura E Abstract BACKGROUND: Aneurysms at the origin of a duplicated middle cerebral artery (DMCA) are quite rare. Here, we report a patient with such an aneurysm successfully...
The Technique of C2 Subfacetal Screw in Patients with High Riding Vertebral Artery. World Neurosurg. 2020 Aug 10;: Authors: Salunke P, Singh A, Karthigeyan M Abstract C2-pedicle screw provides robust construct for fixation in atlantoaxial dislocation (AAD).1-5 However, inserting a C2-pedicle screw with the standard technique in cases with narrow pedicle and high-riding vertebral artery (VA) may endanger the artery.6 A pars-screw is also risky,...
Defining the Border of the Subthalamic Nucleus for Deep Brain Stimulation: A Proposed Model using the Symmetrical Sigmoid Curve Function. World Neurosurg. 2020 Aug 10;: Authors: Chau AMT, Jacques A, Lind CR Abstract BACKGROUND: The subthalamic nucleus (STN) is an important target in deep brain stimulation (DBS). Accurate lead placement is integral for achieving satisfactory clinical outcomes, however the STN remains a structure whose visualization...
Clinical application of DTI in diagnosis and prognosis of hemifacial spasm. World Neurosurg. 2020 Aug 10;: Authors: Jin Z, Li Z Abstract OBJECTIVES: The purpose of this study is test to the application of diffusion tensor imaging (DTI) in patients with hemifacial spasm (HFS), so as to make more accurate diagnoses before surgery and to judge the degree of recovery more accurately after surgical microvascular decompression (MVD). This is the...
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Related Articles Striatal Dopamine Release in Response to Morphine: A [11C]Raclopride Positron Emission Tomography Study in Healthy Men. Biol Psychiatry. 2019 09 01;86(5):356-364 Authors: Spagnolo PA, Kimes A, Schwandt ML, Shokri-Kojori E, Thada S, Phillips KA, Diazgranados N, Preston KL, Herscovitch P, Tomasi D, Ramchandani VA, Heilig M Abstract BACKGROUND: Preclinical and human positron emission tomography studies have produced inconsistent...
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Related Articles Artesunate exerts anti-prolactinoma activity by inhibiting mitochondrial metabolism and inducing apoptosis. Ann Transl Med. 2020 Jul;8(14):858 Authors: Zhang W, Du Q, Bian P, Xiao Z, Wang X, Feng Y, Feng H, Zhu Z, Gao N, Zhu D, Fan X, Zhu Y Abstract Background: Prolactinoma is the most common hormone-secreting pituitary adenoma. Dopamine receptor agonists (DAs) are effective in reducing prolactin levels and tumor mass,...
Related Articles Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells. Front Oncol. 2020;10:1225 Authors: Salvestrini V, Ciciarello M, Pensato V, Simonetti G, Laginestra MA, Bruno S, Pazzaglia M, De Marchi E, Forte D, Orecchioni S, Martinelli G, Bertolini F, Méndez-Ferrer S, Adinolfi E, Di Virgilio F, Cavo M, Curti A Abstract The contribution of cell-extrinsic factors...
Related Articles Cell Cycle Changes, DNA Ploidy, and PTTG1 Gene Expression in HTLV-1 Patients. Front Microbiol. 2020;11:1778 Authors: Levy D, Ferreira MCMR, Reichert CO, de Almeida LV, Brocardo G, Lage LAPC, Culler HF, Nukui Y, Bydlowski SP, Pereira J Abstract Human T-cell lymphotropic virus type-1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). Genetic instability is the hallmark of ATL....
Related Articles Metformin Synergistically Enhanced the Antitumor Activity of Celecoxib in Human Non-Small Cell Lung Cancer Cells. Front Pharmacol. 2020;11:1094 Authors: Cao N, Lu Y, Liu J, Cai F, Xu H, Chen J, Zhang X, Hua ZC, Zhuang H Abstract Celecoxib has potential as an effective antineoplastic agent, but it may exhibit side effects. Given the glucose-addicted properties of tumor cells, metformin is recognized for its inhibitory effect...
Related Articles Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes. Sci Rep. 2020 Aug 13;10(1):13750 Authors: Harmouch E, Seitlinger J, Chaddad H, Ubeaud-Sequier G, Barths J, Saidu S, Désaubry L, Grandemange S, Massfelder T, Fuhrmann G, Fioretti F, Dontenwill M, Benkirane-Jessel N, Idoux-Gillet Y Abstract Glioblastoma (GBM) is one of the most aggressive types of cancer,...
Related Articles Telomere erosion as a placental clock: From placental pathologies to adverse pregnancy outcomes. Placenta. 2020 Aug;97:101-107 Authors: Kohlrausch FB, Keefe DL Abstract The placenta provides nutritional and gas exchange between fetus and mother. Early in pregnancy, placental trophoblasts proliferate rapidly and invade aggressively. As pregnancy progresses, placental cells begin to age. Indeed, pregnancy itself has a tightly...
Tubulin- and ROS-dependent antiproliferative mechanism of a potent analogue of noscapine, N-propargyl noscapine. Life Sci. 2020 Aug 10;:118238 Authors: Nambiar N, Nagireddy PKR, Pedapati R, Kantevari S, Lopus M Abstract AIM: To rationally-design, synthesize, characterize, biologically evaluate, and to elucidate the anticancer mechanism of action of a novel analogue of noscapine, N-propargyl noscapine (NPN), as a potential drug candidate...
Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma. Oncol Lett. 2020 Oct;20(4):52 Authors: Yu X, Fan H, Jiang X, Zheng W, Yang Y, Jin M, Ma X, Jiang W Abstract The clinical outcome of neuroblastoma (NB) has significantly improved in the last 30 years for patients with localized disease; however, the overall survival (OS) for patients with metastasis remains poor. Apatinib, a...
EGFR/FOXO3a/BIM signaling pathway determines chemosensitivity of BMP4-differentiated glioma stem cells to temozolomide. Exp Mol Med. 2020 Aug 12;: Authors: Ciechomska IA, Gielniewski B, Wojtas B, Kaminska B, Mieczkowski J Abstract Accumulating evidence suggests that glioma stem cells (GSCs), which are rare cells characterized by pluripotency and self-renewal ability, are responsible for glioblastoma (GBM) propagation, recurrence and resistance...
The role of α tubulin acetyltransferase αTAT1 in DNA damage response. J Cell Sci. 2020 Aug 11;: Authors: Ryu NM, Kim JM Abstract Lysine 40 acetylation of α tubulin (Ac-α tubulin) catalyzed by acetyltransferase αTAT1, marks stabilized microtubules. Recently, there is growing evidence to suggest the crosstalk between DNA damage response (DDR) and microtubule organization, we therefore investigated whether αTAT1 is involved in DDR. Following...
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer. Breast Cancer Res. 2020 Aug 12;22(1):87 Authors: Portman N, Milioli HH, Alexandrou S, Coulson R, Yong A, Fernandez KJ, Chia KM, Halilovic E, Segara D, Parker A, Haupt S, Haupt Y, Tilley WD, Swarbrick A, Caldon CE, Lim E Abstract BACKGROUND: Resistance to endocrine therapy is a major clinical challenge in the management...
Induction of cell cycle arrest and apoptosis by tomentosin in hepatocellular carcinoma HepG2 and Huh7 cells. Hum Exp Toxicol. 2020 Aug 13;:960327120943935 Authors: Yu SH, Lee CM, Ha SH, Lee J, Jang KY, Park SH Abstract Tomentosin, a sesquiterpene lactone, is known to possess various biological activities. However, its anticarcinogenic activity against human hepatocellular carcinoma (HCC) cells has not been investigated in detail. Thus,...
Syntheses and Evaluation of New Bisacridine Derivatives for Dual Binding of G-Quadruplex and i-Motif in Regulating Oncogene c-myc Expression. J Med Chem. 2020 Aug 12;: Authors: Kuang GT, Zhang M, Kang S, Hu D, Li X, Wei Z, Gong X, An LK, Huang ZS, Shu B, Li D Abstract c-myc oncogene is an important regulator for cell growth and differentiation, and its aberrant overexpression is closely related to the occurrence and development of various...
Related Articles Quantifying the Landscape and Transition Paths for Proliferation-Quiescence Fate Decisions. J Clin Med. 2020 Aug 10;9(8): Authors: Chen Z, Li C Abstract The cell cycle, essential for biological functions, experiences delicate spatiotemporal regulation. The transition between G1 and S phase, which is called the proliferation-quiescence decision, is critical to the cell cycle. However, the stability and underlying stochastic...
Related Articles Limits and Constraints on Mechanisms of Cell-Cycle Regulation Imposed by Cell Size-Homeostasis Measurements. Cell Rep. 2020 Aug 11;32(6):107992 Authors: Willis L, Jönsson H, Huang KC Abstract High-throughput imaging has led to an explosion of observations about cell-size homeostasis across the kingdoms of life. Among bacteria, "adder" behavior-in which a constant size increment appears to be added during each cell cycle-is...
Related Articles Multiple myeloma: Combination therapy of BET proteolysis targeting chimeric molecule with CDK9 inhibitor. PLoS One. 2020;15(6):e0232068 Authors: Lim SL, Xu L, Han BC, Shyamsunder P, Chng WJ, Koeffler HP Abstract Cyclin Dependent Kinase 9 (CDK9) associates with Bromodomain and Extra-Terminal Domain (BET) proteins to promote transcriptional elongation by phosphorylation of serine 2 of RNAP II C-terminal domain. We examined the...
Related Articles Silencing Lysine-Specific Histone Demethylase 1 (LSD1) Causes Increased HP1-Positive Chromatin, Stimulation of DNA Repair Processes, and Dysregulation of Proliferation by Chk1 Phosphorylation in Human Endothelial Cells. Cells. 2019 10 07;8(10): Authors: Wojtala M, Dąbek A, Rybaczek D, Śliwińska A, Świderska E, Słapek K, El-Osta A, Balcerczyk A Abstract : The methylation of histone lysine residues modifies chromatin conformation...
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Related Articles Herpes Simplex Virus Encephalitis after temporal lobe resection: an infrequent but treatable complication of epilepsy surgery. Eur J Neurol. 2020 Aug 14;: Authors: Martínez-Poles J, Toledano R, Aledo-Serrano Á, Korn K, Coras R, Blümcke I, García-Morales I, Álvarez-Linera J, Gil-Nagel A Abstract Herpes simplex virus (HSV) encephalitis is the most common sporadic viral encephalitis and has been associated with refractory epilepsy....
Related Articles The study of microtubule dynamics and stability at the postsynaptic density in a rat pilocarpine model of temporal lobe epilepsy. Ann Transl Med. 2020 Jul;8(14):863 Authors: Wu X, Zhou Y, Huang Z, Cai M, Shu Y, Zeng C, Feng L, Xiao B, Zhan Q Abstract Background: The recurrence and drug resistance of temporal lobe epilepsy (TLE) has been ceaselessly challenging scientists and epilepsy experts. There has been an accumulation of...
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