Related Articles Epidemiology of neurologic disease in pregnancy. Handb Clin Neurol. 2020;171:119-141 Authors: Barghouthi T, Lemley R, Figurelle M, Bushnell C Abstract Many neurologic diseases in women are influenced by the physiologic and hormonal changes of pregnancy, and pregnancy itself poses challenges in both treatment and evaluation of these conditions. Some diseases, such as epilepsy and multiple sclerosis, have a high enough prevalence...
Sun Aug 02, 2020 15:40
Neurocognitive Profiles of Pediatric Patients with ESES, Generalized Epilepsy, or Focal Epilepsy. Epilepsy Res. 2020 May 06;167:106351 Authors: Ng R, Hodges E Abstract To date, the neurocognitive profile and comorbid psychiatric risks associated with ESES, a syndrome that commonly coincides with a seizure disorder, in contrast to generalized or partial/focal epilepsy without ESES remains unclear. Accordingly, this preliminary study aimed to...
Sat Aug 01, 2020 15:10
Related Articles Ketogenic Diet Provided During Three Months Increases KCC2 Expression but Not NKCC1 in the Rat Dentate Gyrus. Front Neurosci. 2020;14:673 Authors: Granados-Rojas L, Jerónimo-Cruz K, Juárez-Zepeda TE, Tapia-Rodríguez M, Tovar AR, Rodríguez-Jurado R, Carmona-Aparicio L, Cárdenas-Rodríguez N, Coballase-Urrutia E, Ruíz-García M, Durán P Abstract Ketogenic diet, a high fat and low carbohydrate diet, has been used as a non-pharmacological...
Sat Aug 01, 2020 15:10
Related Articles A Standardized Electrode Nomenclature for Stereoelectroencephalography Applications. J Clin Neurophysiol. 2020 Jul 23;: Authors: Stone S, Madsen JR, Bolton J, Pearl PL, Chavakula V, Day E Abstract PURPOSE: Stereoelectroencephalography (SEEG) is widely performed on individuals with medically refractory epilepsy for whom invasive seizure localization is desired. Despite increasing adoption in many centers across the world, no...
Sat Aug 01, 2020 15:10
Related Articles Prenatal clinical manifestations in individuals with COL4A1/2 variants. J Med Genet. 2020 Jul 30;: Authors: Itai T, Miyatake S, Taguri M, Nozaki F, Ohta M, Osaka H, Morimoto M, Tandou T, Nohara F, Takami Y, Yoshioka F, Shimokawa S, Okuno-Yuguchi J, Motobayashi M, Takei Y, Fukuyama T, Kumada S, Miyata Y, Ogawa C, Maki Y, Togashi N, Ishikura T, Kinoshita M, Mitani Y, Kanemura Y, Omi T, Ando N, Hattori A, Saitoh S, Kitai Y, Hirai S, Arai H, Ishida...
Sat Aug 01, 2020 15:10
Related Articles Actigraph-Measured Movement Correlates of Attention-Deficit/Hyperactivity Disorder (ADHD) Symptoms in Young People with Tuberous Sclerosis Complex (TSC) with and without Intellectual Disability and Autism Spectrum Disorder (ASD). Brain Sci. 2020 Jul 28;10(8): Authors: Earnest T, Shephard E, Tye C, McEwen F, Woodhouse E, Liang H, Sheerin F, Bolton PF Abstract Actigraphy, an objective measure of motor activity, reliably indexes...
Sat Aug 01, 2020 15:10
Related Articles Saudi Epilepsy Society consensus on epilepsy management during the COVID-19 Pandemic. Neurosciences (Riyadh). 2020 07;25(3):222-225 Authors: Alotaibi F, Althani Z, Aljaafari D, Tayeb HO, Baarmah D, Aljalal N, Muthaffar O, Alqulaiti K, Alhameed M, Ali B, Qureshi S, Albaradie R PMID: 32683406 [PubMed - indexed for MEDLINE]
Sat Aug 01, 2020 15:10
Related Articles Noninvasive electromagnetic source imaging of spatiotemporally distributed epileptogenic brain sources. Nat Commun. 2020 04 23;11(1):1946 Authors: Sohrabpour A, Cai Z, Ye S, Brinkmann B, Worrell G, He B Abstract Brain networks are spatiotemporal phenomena that dynamically vary over time. Functional imaging approaches strive to noninvasively estimate these underlying processes. Here, we propose a novel source imaging approach...
Sat Aug 01, 2020 15:10
Related Articles Novel congenital disorder of O-linked glycosylation caused by GALNT2 loss of function. Brain. 2020 04 01;143(4):1114-1126 Authors: Zilmer M, Edmondson AC, Khetarpal SA, Alesi V, Zaki MS, Rostasy K, Madsen CG, Lepri FR, Sinibaldi L, Cusmai R, Novelli A, Issa MY, Fenger CD, Abou Jamra R, Reutter H, Briuglia S, Agolini E, Hansen L, Petäjä-Repo UE, Hintze J, Raymond KM, Liedtke K, Stanley V, Musaev D, Gleeson JG, Vitali C, O'Brien WT, Gardella E,...
Sat Aug 01, 2020 15:10
Related Articles Electrographic predictors of successful weaning from anaesthetics in refractory status epilepticus. Brain. 2020 04 01;143(4):1143-1157 Authors: Rubin DB, Angelini B, Shoukat M, Chu CJ, Zafar SF, Westover MB, Cash SS, Rosenthal ES Abstract Intravenous third-line anaesthetic agents are typically titrated in refractory status epilepticus to achieve either seizure suppression or burst suppression on continuous EEG. However, the...
Sat Aug 01, 2020 15:10
Related Articles Postoperative Complications of Box-Shift Osteotomy for Orbital Hypertelorism. J Craniofac Surg. 2020 Mar/Apr;31(2):385-388 Authors: Jiang T, Yu Z, Chi TY, Kang BK, Gao J, Wei M, Yuan J, Xu L, Duan H, Mu X, Cao D Abstract OBJECTIVE: To summarize and analyze the postoperative complications of box-shift osteotomy performed at our center for Chinese orbital hypertelorism patients from 2008 to 2017. METHOD: This retrospective...
Sat Aug 01, 2020 15:10
Related Articles Cognitive performances in patients affected by late-onset epilepsy with unknown etiology: A 12-month follow-up study. Epilepsy Behav. 2019 12;101(Pt A):106592 Authors: Liguori C, Costa C, Franchini F, Izzi F, Spanetta M, Cesarini EN, Di Santo S, Manfredi N, Farotti L, Romoli M, Lanari A, Salvadori N, Parnetti L, Calabresi P, Mercuri NB, Placidi F Abstract INTRODUCTION: Epilepsy has a growing frequency, particularly in the elderly....
Sat Aug 01, 2020 15:10
Related Articles Temporal lobe surgery and memory: Lessons, risks, and opportunities. Epilepsy Behav. 2019 12;101(Pt A):106596 Authors: Bauman K, Devinsky O, Liu AA Abstract Careful study of the clinical outcomes of temporal lobe epilepsy (TLE) surgery has greatly advanced our knowledge of the neuroanatomy of human memory. After early cases resulted in profound amnesia, the critical role of the hippocampus and associated medial temporal lobe...
Sat Aug 01, 2020 15:10
Related Articles Prevalence of valproate prescriptions in women of childbearing age in certain regions of Russia. Epilepsy Behav. 2019 12;101(Pt A):106584 Authors: Kostev K, Osina G, Rider F, Guekht A Abstract AIM: The goal of this retrospective study was to analyze the proportion of women with epilepsy who had received valproate (VPA) prescriptions in certain regions of Russia in 2018. METHODS: This retrospective cross-sectional study...
Sat Aug 01, 2020 15:10
Related Articles Multidisciplinary management improves anxiety, depression, medication adherence, and quality of life among patients with epilepsy in eastern China: A prospective study. Epilepsy Behav. 2019 11;100(Pt A):106400 Authors: Zheng Y, Ding X, Guo Y, Chen Q, Wang W, Zheng Y, Wang S, Ding Y, Ding M Abstract OBJECTIVE: The objective of this study was to investigate the effect of a multidisciplinary program on anxiety, depression, medication...
Sat Aug 01, 2020 15:10
Related Articles Sexual dysfunction in people with epilepsy. Epilepsy Behav. 2019 11;100(Pt A):106495 Authors: Rathore C, Henning OJ, Luef G, Radhakrishnan K Abstract Sexual dysfunction is a common comorbidity in people with epilepsy (PWE) that adversely affects their quality of life. Nearly one-half of men and women with epilepsy have sexual dysfunction, but in the majority, this often goes unnoticed. The wide variation in the reported prevalence...
Sat Aug 01, 2020 15:10
Related Articles Assessment of psychiatric and behavioral adverse effects of antiepileptic drugs monotherapy: Could they have a neuroendocrine correlation in persons with epilepsy? Epilepsy Behav. 2019 11;100(Pt A):106439 Authors: Sarangi SC, Kaur N, Tripathi M Abstract OBJECTIVE: The study investigated overall adverse event (AE) burden and specifically psychiatric and behavioral side effects (PBAEs) in persons with epilepsy (PWE) on antiepileptic...
Sat Aug 01, 2020 15:10
Related Articles Readmission Following Surgical Resection for Intractable Epilepsy: Nationwide Rates, Causes, Predictors, and Outcomes. Oper Neurosurg (Hagerstown). 2019 03 01;16(3):374-382 Authors: Rumalla K, Smith KA, Arnold PM, Schwartz TH Abstract BACKGROUND: Hospital readmissions can be detrimental to patients and may interfere with the potential benefits of the therapeutic procedure. Government agencies have begun to focus on reducing...
Sat Aug 01, 2020 15:10
Levetiracetam and Suicidality: A Case Report and Literature Review. Prim Care Companion CNS Disord. 2020 Jul 30;22(4): Authors: Esang M, Santos MG, Ahmed S Abstract Objective: To identify clinical characteristics common among epileptic patients prescribed levetiracetam who report suicidal ideation or who exhibit suicidal behavior. A case is also provided that highlights the need for increased vigilance for neuropsychiatric sequelae in fragile...
Fri Jul 31, 2020 13:56
Long-term safety and efficacy of brivaracetam in adults with focal seizures: Results from an open-label, multinational, follow-up trial. Epilepsy Res. 2020 Jun 23;166:106404 Authors: Arnold S, Laloyaux C, Schulz AL, Elmoufti S, Yates S, Fakhoury T Abstract BACKGROUND: This long-term follow-up (LTFU) trial was conducted to evaluate the long-term safety and tolerability of brivaracetam (BRV) at individualized doses (maximum of 200 mg/day) in...
Fri Jul 31, 2020 13:56
Peripheral blood expression levels of inflammasome complex components in two different focal epilepsy syndromes. J Neuroimmunol. 2020 Jul 22;347:577343 Authors: Ulusoy C, Vanlı-Yavuz EN, Şanlı E, Timirci-Kahraman Ö, Yılmaz V, Bebek N, Küçükali Cİ, Baykan B, Tüzün E Abstract BACKGROUND: Although the role of inflammation in epilepsy pathogenesis has been extensively investigated, the inflammasome complex, a key component of neuroinflammation,...
Fri Jul 31, 2020 13:56
Vigabatrin add-on therapy for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2020 Jul 30;7:CD007302 Authors: Bresnahan R, Gianatsi M, Maguire MJ, Tudur Smith C, Marson AG Abstract BACKGROUND: This is an updated version of the original Cochrane Review published in 2008 and updated in 2013. Epilepsy is a common neurological condition which affects up to 1% of the population. Approximately 30% of people with epilepsy do not respond...
Fri Jul 31, 2020 13:56
Related Articles Neuropsychological functioning in survivors of childhood medulloblastoma/CNS-PNET: The role of secondary medical complications. Clin Neuropsychol. 2020 Jul 30;:1-26 Authors: Stadskleiv K, Stensvold E, Stokka K, Bechensteen AG, Brandal P Abstract OBJECTIVE: To investigate the long-term cognitive consequences of malignant pediatric brain tumor and its treatment, and factors explaining variability in cognitive functioning among...
Fri Jul 31, 2020 13:56
Related Articles Epidiolex-induced skin rash. Epileptic Disord. 2020 Jul 30;: Authors: Singh J, Antimisiaris MF Abstract Epidiolex® (cannabidiol, aka CBD) is a recently approved FDA prescription drug for the treatment of epilepsy associated with Lennox-Gastaut and Dravet syndromes, and is increasingly used for treatment-resistant epilepsy. Rash was rarely reported in Epidiolex® clinical trial data. We report a case of Epidiolex®-related skin...
Fri Jul 31, 2020 13:56
Related Articles The Potential Therapeutic Role of the HMGB1-TLR Pathway in Epilepsy. Curr Drug Targets. 2020 Jul 29;: Authors: Wang S, Guan Y, Li T Abstract Epilepsy is one of the most common serious neurological disorders, affecting over 70 million people world-wide. For treatment of epilepsy, antiepileptic drugs (AEDs) and surgeries are widely used. However, drug resistance and adverse effects indicate the need to develop targeted AEDs based...
Fri Jul 31, 2020 13:56
Related Articles Autoimmune Encephalitis in Children: An Update. Indian Pediatr. 2020 Jul 15;57(7):662-670 Authors: Garg D, Mohammad SS, Sharma S Abstract CONTEXT: Autoimmune encephalitis has acquired immense significance as a treatable cause of encephalopathy, epilepsy and movement disorders in children. In this review, we discuss the various clinical syndromes, diagnosis, treatment and prognosis in children. EVIDENCE ACQUISITION:...
Fri Jul 31, 2020 13:56
Related Articles Epilepsy in veterinary patients: perspectives of Dutch veterinarians in first-line practice. Vet Rec. 2020 Jul 29;: Authors: Santifort KM, Hamers M, Mandigers P Abstract BACKGROUND: This study aims to investigate the perspectives of veterinarians in first-line practice on confidence and satisfaction regarding several important aspects of the description, diagnosis and treatment of canine patients with epilepsy. METHODS:...
Fri Jul 31, 2020 13:56
Related Articles Anticonvulsant long-term and rescue medication: The children's perspective. Eur J Paediatr Neurol. 2020 Jul 14;: Authors: Woltermann S, Jeschke S, Herziger B, Müller RM, Kiess W, Bertsche T, Bertsche A, Neininger MP Abstract BACKGROUND: Little is known about children's perspectives and attitudes towards their long-term and rescue anticonvulsant medication. METHODS: We interviewed paediatric patients aged 6-18 years...
Fri Jul 31, 2020 13:56
Related Articles Epileptic brain fluorescent imaging reveals apigenin can relieve the myeloperoxidase-mediated oxidative stress and inhibit ferroptosis. Proc Natl Acad Sci U S A. 2020 05 12;117(19):10155-10164 Authors: Shao C, Yuan J, Liu Y, Qin Y, Wang X, Gu J, Chen G, Zhang B, Liu HK, Zhao J, Zhu HL, Qian Y Abstract Myeloperoxidase (MPO)-mediated oxidative stress has been suggested to play an important role in the pathological dysfunction...
Fri Jul 31, 2020 13:56
Related Articles Fetal loss and malformations in the MONEAD study of pregnant women with epilepsy. Neurology. 2020 04 07;94(14):e1502-e1511 Authors: Meador KJ, Pennell PB, May RC, Van Marter L, McElrath TF, Brown C, Gerard E, Kalayjian L, Gedzelman E, Penovich P, Cavitt J, French J, Hwang S, Pack AM, Sam M, Birnbaum AK, Finnell R, MONEAD Investigator Group Abstract OBJECTIVE: To examine occurrence of severe adverse fetal outcomes (SAO), including...
Fri Jul 31, 2020 13:56
Related Articles Large-Scale Communication in the Human Brain Is Rhythmically Modulated through Alpha Coherence. Curr Biol. 2019 09 09;29(17):2801-2811.e5 Authors: Chapeton JI, Haque R, Wittig JH, Inati SK, Zaghloul KA Abstract Recent evidence has suggested that coherent neuronal oscillations may serve as a gating mechanism for flexibly modulating communication between brain regions. For this to occur, such oscillations should be robust and...
Fri Jul 31, 2020 13:56
Related Articles Predictors of seizure recurrence in patients with surgery for focal cortical dysplasia: pairwise and network meta-analysis and trial sequential analysis. Childs Nerv Syst. 2019 05;35(5):753-767 Authors: Chen J, Chen X, Huang C, Zhu H, Hou Z, An N, Liu SY, Yang H, Zhang CQ Abstract OBJECT: The aim of this study was to determine the predictors of seizure recurrence in surgery for focal cortical dysplasia (FCD) by conducting a...
Fri Jul 31, 2020 13:56
Related Articles A case of focal cortical dysplasia type Ib atypically showing reversible intensity changes on magnetic resonance imaging which could be affected by epileptic discharge activity. Childs Nerv Syst. 2019 05;35(5):883-887 Authors: Kuroda N, Fujimoto A, Enoki H, Arai Y, Okanishi T Abstract Focal cortical dysplasia (FCD) was first described as a distinct neuropathological entity in 1971 by Taylor and colleagues. FCD is thought to...
Fri Jul 31, 2020 13:56
Related Articles Bibliometric Analysis of Chronic Traumatic Encephalopathy Research from 1999 to 2019. Int J Environ Res Public Health. 2020 Jul 28;17(15): Authors: Qi B, Jin S, Qian H, Zou Y Abstract Research on chronic traumatic encephalopathy (CTE) has increased over the past two decades. However, few studies have statistically analyzed these publications. In this work, we conducted a bibliometric analysis of studies on CTE to track research...
Sat Aug 01, 2020 13:59
Related Articles Repetitive Pain in Neonatal Male Rats Impairs Hippocampus-Dependent Fear Memory Later in Life. Front Neurosci. 2020;14:722 Authors: Xia D, Min C, Chen Y, Ling R, Chen M, Li X Abstract Preterm infants in neonatal intensive care units are inevitably subjected to numerous painful procedures. However, little is known about the consequences of early pain experience on fear memory formation later in life. We hypothesized that exposure...
Sat Aug 01, 2020 13:22
Related Articles LRRK2 and Protein Aggregation in Parkinson's Disease: Insights From Animal Models. Front Neurosci. 2020;14:719 Authors: Dues DJ, Moore DJ Abstract Mutations in leucine-rich repeat kinase 2 (LRRK2) instigate an autosomal dominant form of Parkinson's disease (PD). Despite the neuropathological heterogeneity observed in LRRK2-PD, accumulating evidence suggests that alpha-synuclein and tau pathology are observed in a vast majority...
Sat Aug 01, 2020 13:22
Related Articles Systems Biology Approaches to Understand the Host-Microbiome Interactions in Neurodegenerative Diseases. Front Neurosci. 2020;14:716 Authors: Rosario D, Boren J, Uhlen M, Proctor G, Aarsland D, Mardinoglu A, Shoaie S Abstract Neurodegenerative diseases (NDDs) comprise a broad range of progressive neurological disorders with multifactorial etiology contributing to disease pathophysiology. Evidence of the microbiome involvement...
Sat Aug 01, 2020 13:22
Related Articles Brain Metabolisms Involved in Self-Reported Quality of Mobility in Parkinson's Disease. Front Neurosci. 2020;14:715 Authors: Fei L, Liu FT, Liu YQ, Ge JJ, Lu JY, He SJ, Sun YM, Wu JJ, Zuo CT, Wang J Abstract Background: Objective motor ratings and subjective motor complaints are both widely used in Parkinson's disease (PD). However, the objective basis to the self-perceived mobility quality is still not well elucidated. ...
Sat Aug 01, 2020 13:22
Related Articles Prediction of Malignant Acute Middle Cerebral Artery Infarction via Computed Tomography Radiomics. Front Neurosci. 2020;14:708 Authors: Wen X, Li Y, He X, Xu Y, Shu Z, Hu X, Chen J, Jiang H, Gong X Abstract Malignant middle cerebral artery infarction (mMCAi) is a serious complication of cerebral infarction usually associated with poor patient prognosis. In this retrospective study, we analyzed clinical information as well as...
Sat Aug 01, 2020 13:22
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