Related Articles Evaluating Circadian Dysfunction in Mouse Models of Alzheimer's Disease: Where Do We Stand? Front Neurosci. 2020;14:703 Authors: Sheehan PW, Musiek ES Abstract Circadian dysfunction has been described in patients with symptomatic Alzheimer's disease (AD), as well as in presymptomatic phases of the disease. Modeling this circadian dysfunction in mouse models would provide an optimal platform for understanding mechanisms and developing...
Sat Aug 01, 2020 13:22
Related Articles Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT1A-Mediated cAMP Signaling. Front Neurosci. 2020;14:701 Authors: Li J, Chen L, Li G, Chen X, Hu S, Zheng L, Luria V, Lv J, Sun Y, Xu Y, Yu Y Abstract Background: Major depressive disorder (MDD) is a severe mental disorder related to the deficiency of monoamine neurotransmitters, particularly to abnormalities of 5-HT (5-hydroxytryptamine,...
Sat Aug 01, 2020 13:22
Related Articles A Review of Hematoma Components Clearance Mechanism After Subarachnoid Hemorrhage. Front Neurosci. 2020;14:685 Authors: Pan P, Xu L, Zhang H, Liu Y, Lu X, Chen G, Tang H, Wu J Abstract Subarachnoid hemorrhage (SAH) is a complicated clinical syndrome, which is caused by several kinds of cerebrovascular disorders, with high morbidity, disability and mortality rate. In recent years, several studies have shown that early brain injury...
Sat Aug 01, 2020 13:22
Related Articles Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia. Front Neurosci. 2020;14:684 Authors: Ranganathan R, Haque S, Coley K, Shepheard S, Cooper-Knock J, Kirby J Abstract Amyotrophic lateral sclerosis and frontotemporal dementia are two progressive, adult onset neurodegenerative diseases, caused by the cell death of motor neurons in the motor cortex and spinal cord and cortical neurons in the frontal and...
Sat Aug 01, 2020 13:22
Related Articles The Role of Amygdala in Self-Conscious Emotions in a Patient With Acquired Bilateral Damage. Front Neurosci. 2020;14:677 Authors: Piretti L, Pappaianni E, Lunardelli A, Zorzenon I, Ukmar M, Pesavento V, Rumiati RI, Job R, Grecucci A Abstract Shame plays a fundamental role in the regulation of our social behavior. One intriguing question is whether amygdala might play a role in processing this emotion. In the present single-case...
Sat Aug 01, 2020 13:22
Related Articles Down Syndrome Is a Metabolic Disease: Altered Insulin Signaling Mediates Peripheral and Brain Dysfunctions. Front Neurosci. 2020;14:670 Authors: Dierssen M, Fructuoso M, Martínez de Lagrán M, Perluigi M, Barone E Abstract Down syndrome (DS) is the most frequent chromosomal abnormality that causes intellectual disability, resulting from the presence of an extra complete or segment of chromosome 21 (HSA21). In addition, trisomy...
Sat Aug 01, 2020 13:22
Related Articles Elevating Insulin Signaling Using a Constitutively Active Insulin Receptor Increases Glucose Metabolism and Expression of GLUT3 in Hippocampal Neurons. Front Neurosci. 2020;14:668 Authors: Frazier HN, Ghoweri AO, Anderson KL, Lin RL, Popa GJ, Mendenhall MD, Reagan LP, Craven RJ, Thibault O Abstract Insulin signaling is an integral component of healthy brain function, with evidence of positive insulin-mediated alterations in...
Sat Aug 01, 2020 13:22
Related Articles Mapping the Contrast Sensitivity of the Visual Field With Bayesian Adaptive qVFM. Front Neurosci. 2020;14:665 Authors: Xu P, Lesmes LA, Yu D, Lu ZL Abstract Current clinical evaluation, which focuses on central vision, could be improved through characterization of residual vision with peripheral testing of visual acuity, contrast sensitivity, color vision, crowding, and reading speed. Assessing visual functions in addition to...
Sat Aug 01, 2020 13:22
Related Articles Sensory Feedback in Hand Prostheses: A Prospective Study of Everyday Use. Front Neurosci. 2020;14:663 Authors: Wijk U, Carlsson IK, Antfolk C, Björkman A, Rosén B Abstract Introduction: Sensory feedback in hand prostheses is lacking but wished for. Many amputees experience a phantom hand map on their residual forearm. When the phantom hand map is touched, it is experienced as touch on the amputated hand. A non-invasive sensory...
Sat Aug 01, 2020 13:22
Related Articles Levodopa Changes Functional Connectivity Patterns in Subregions of the Primary Motor Cortex in Patients With Parkinson's Disease. Front Neurosci. 2020;14:647 Authors: Shen Y, Hu J, Chen Y, Liu W, Li Y, Yan L, Xie C, Zhang W, Yu M, Liu W Abstract Background: The primary motor cortex (M1) is a critical node in Parkinson's disease (PD)-related motor circuitry; however, the functional roles of its subregions are poorly understood....
Sat Aug 01, 2020 13:22
Related Articles Corrigendum: An Evolutionarily Threat-Relevant Odor Strengthens Human Fear Memory. Front Neurosci. 2020;14:638 Authors: Taylor JE, Lau H, Seymour B, Nakae A, Sumioka H, Kawato M, Koizumi A Abstract [This corrects the article DOI: 10.3389/fnins.2020.00255.]. PMID: 32733185 [PubMed - in process]
Sat Aug 01, 2020 13:22
Related Articles Is Ross Syndrome a New Type of Synucleinopathy? A Brief Research Report. Front Neurosci. 2020;14:635 Authors: Ma M, Yao J, Chen Y, Liu H, Xia D, Tian H, Wang X, Wu E, Wang X, Ding X Abstract Ross syndrome (RS) is a rare peripheral autonomic system disorder characterized by tonic pupil, hyporeflexia, and segmental anhidrosis. Neuropathological studies show that RS results from the selective cholinergic nerve degeneration. However,...
Sat Aug 01, 2020 13:22
Related Articles Beneficial Effects of Musicality on the Development of Productive Phonology Skills in Second Language Acquisition. Front Neurosci. 2020;14:618 Authors: Delogu F, Zheng Y Abstract Previous studies show beneficial effects of musicality on the acquisition of a second language (L2). While most research focused on perceptual aspects, only few studies investigated the effects of musicality on productive phonology. The present study...
Sat Aug 01, 2020 13:22
Related Articles EEG Biomarkers Related With the Functional State of Stroke Patients. Front Neurosci. 2020;14:582 Authors: Sebastián-Romagosa M, Udina E, Ortner R, Dinarès-Ferran J, Cho W, Murovec N, Matencio-Peralba C, Sieghartsleitner S, Allison BZ, Guger C Abstract Introduction: Recent studies explored promising new quantitative methods to analyze electroencephalography (EEG) signals. This paper analyzes the correlation of two EEG parameters,...
Sat Aug 01, 2020 13:22
Related Articles Thirty Mouse Strain Survey of Voluntary Physical Activity and Energy Expenditure: Influence of Strain, Sex and Day-Night Variation. Front Neurosci. 2020;14:531 Authors: König C, Plank AC, Kapp A, Timotius IK, von Hörsten S, Zimmermann K Abstract We measured indirect calorimetry and activity parameters, VO2 and VCO2 to extract respiratory exchange ratio (RER) and energy expenditure in both sexes of 30 inbred mouse strains of...
Sat Aug 01, 2020 13:22
Related Articles On-Chip Training Spiking Neural Networks Using Approximated Backpropagation With Analog Synaptic Devices. Front Neurosci. 2020;14:423 Authors: Kwon D, Lim S, Bae JH, Lee ST, Kim H, Seo YT, Oh S, Kim J, Yeom K, Park BG, Lee JH Abstract Hardware-based spiking neural networks (SNNs) inspired by a biological nervous system are regarded as an innovative computing system with very low power consumption and massively parallel operation....
Sat Aug 01, 2020 13:22
Related Articles Second Harmonic Generation Imaging of Collagen in Chronically Implantable Electrodes in Brain Tissue. Front Neurosci. 2020;14:95 Authors: Esquibel CR, Wendt KD, Lee HC, Gaire J, Shoffstall A, Urdaneta ME, Chacko JV, Brodnick SK, Otto KJ, Capadona JR, Williams JC, Eliceiri KW Abstract Advances in neural engineering have brought about a number of implantable devices for improved brain stimulation and recording. Unfortunately,...
Sat Aug 01, 2020 13:22
Effectiveness of peer support intervention on perinatal depression: A systematic review and meta-analysis. J Affect Disord. 2020 Jul 15;276:788-796 Authors: Huang R, Yan C, Tian Y, Lei B, Yang D, Liu D, Lei J Abstract BACKGROUND: It has been suggested that peer support intervention may offer an alternative approach to prevent or treat perinatal depression, but little is known about its effectiveness, economics, and satisfaction in the...
Sun Aug 02, 2020 13:39
Active surveillance in desmoid-type fibromatosis: A systematic literature review. Eur J Cancer. 2020 Jul 29;137:18-29 Authors: Timbergen MJM, Schut AW, Grünhagen DJ, Sleijfer S, Verhoef C Abstract BACKGROUND: This study evaluates the results of the active surveillance (AS) approach in adult patients with desmoid-type fibromatosis (DTF) because AS is advocated as a front-line approach for DTF in the European consensus guidelines. ...
Sun Aug 02, 2020 13:39
Related Articles Prognostic Significance of Complete Pathologic Response Obtained with Chemotherapy Versus Chemoradiotherapy in Gastric Cancer. Ann Surg Oncol. 2020 Jul 31;: Authors: Trumbull DA, Lemini R, Díaz Vico T, Jorgensen MS, Attwood K, Ji W, Brady M, Gabriel E, Kukar M Abstract BACKGROUND: Few studies have compared the survival advantage of complete pathologic response (cPR) achieved through neoadjuvant chemotherapy (nCT) versus...
Sun Aug 02, 2020 13:39
Related Articles Assessing the risk of venous thromboembolism in multiple myeloma. Thromb Res. 2020 Jul;191 Suppl 1:S74-S78 Authors: Sanfilippo KM Abstract Patients with multiple myeloma (MM) have an increased risk of venous thromboembolism (VTE) compared to the general population. This risk is highest during the first year of diagnosis and subsequently decreases over time. Development of VTE in patients with MM is associated with inferior...
Sun Aug 02, 2020 13:39
Related Articles Overview of risk assessment models for venous thromboembolism in ambulatory patients with cancer. Thromb Res. 2020 Jul;191 Suppl 1:S50-S57 Authors: Gerotziafas GT, Mahé I, Lefkou E, AboElnazar E, Abdel-Razeq H, Taher A, Antic D, Elalamy I, Syrigos K, Van Dreden P Abstract A B S T R A C T Important progress has been made in the development of risk assessment models (RAM) for the identification of outpatients on anticancer...
Sun Aug 02, 2020 13:39
Related Articles ATM mutations improve radio-sensitivity in wild-type isocitrate dehydrogenase-associated high-grade glioma: retrospective analysis using next-generation sequencing data. Radiat Oncol. 2020 Jul 31;15(1):184 Authors: Kim N, Kim SH, Kang SG, Moon JH, Cho J, Suh CO, In Yoon H, Chang JH Abstract BACKGROUND: To identify the association between somatic ataxia-telangiectasia mutated (ATM) mutations and improved radio-sensitivity,...
Sun Aug 02, 2020 13:39
Related Articles Evaluating different adoption scenarios for TIL-therapy and the influence on its (early) cost-effectiveness. BMC Cancer. 2020 Jul 31;20(1):712 Authors: Lindenberg M, Retèl V, Rohaan M, van den Berg J, Haanen J, van Harten W Abstract BACKGROUND: Treatment with tumor-Infiltrating Lymphocytes (TIL) is an innovative therapy for advanced melanoma with promising clinical phase I/II study results and likely beneficial cost-effectiveness....
Sun Aug 02, 2020 13:39
Related Articles Evaluating entrectinib as a treatment option for non-small cell lung cancer. Expert Opin Pharmacother. 2020 Jul 31;:1-8 Authors: Lee J, Park S, Jung HA, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ Abstract INTRODUCTION: Entrectinib, an oral pan-TRK, ALK, and ROS1 inhibitor is approved as a first-line treatment for NTRK-rearranged solid tumors and ROS1-rearranged non-small cell lung cancer (NSCLC). It has demonstrated clinical...
Sun Aug 02, 2020 13:39
Prognostic impact of CD8-positive tumour-infiltrating lymphocytes and PD-L1 expression in salivary gland cancer. Oral Oncol. 2020 Jul 28;111:104931 Authors: Kesar N, Winkelmann R, Oppermann J, Ghanaati S, Martin D, Neumayer T, Balster S, Rödel C, Rödel F, von der Grün J, Balermpas P Abstract OBJECTIVES: Aim of the study was to evaluate the prognostic impact of CD8-positive (CD8+) tumour-infiltrating lymphocytes (TILs) and PD-L1 expression on...
Sat Aug 01, 2020 13:35
Diagnostic Spectro-cytology revealing differential recognition of cervical Cancer lesions by label-free surface enhanced Raman fingerprints and Chemomssetrics. Nanomedicine. 2020 Jul 28;:102276 Authors: Karunakaran V, Saritha VN, Joseph MM, Nair JB, Saranya G, Raghu KG, Sujathan K, Kumar KS, Maiti KK Abstract Herein we have stepped-up on a strategic spectroscopic modality by utilizing label free ultrasensitive surface enhanced Raman scattering...
Sat Aug 01, 2020 13:35
Classification of extrachromosomal circular DNA with a focus on the role of extrachromosomal DNA (ecDNA) in tumor heterogeneity and progression. Biochim Biophys Acta Rev Cancer. 2020 Jul 28;:188392 Authors: Liao Z, Jiang W, Ye L, Li T, Yu X, Liu L Abstract Although the eukaryotic genome is mainly comprised of linear chromosomal DNA, genes can also be found outside of chromosomes. The unconventional presence of extrachromosomal genes is usually...
Sat Aug 01, 2020 13:35
Artificial Intelligence in Lung Cancer: Bridging the Gap Between Computational Power and Clinical Decision-Making. Can Assoc Radiol J. 2020 Jul 31;:846537120941434 Authors: Christie JR, Lang P, Zelko LM, Palma DA, Abdelrazek M, Mattonen SA Abstract Lung cancer remains the most common cause of cancer death worldwide. Recent advances in lung cancer screening, radiotherapy, surgical techniques, and systemic therapy have led to increasing...
Sat Aug 01, 2020 13:35
Overview of Delivery of Cancer Care in Nepal: Current Status and Future Priorities. JCO Glob Oncol. 2020 Jul;6:1211-1217 Authors: Gyawali B, Sharma S, Shilpakar R, Dulal S, Pariyar J, Booth CM, Sharma Poudyal B Abstract Nepal is a small, low-income country between India and China with a unique health care delivery system. Cancer is becoming an important public health problem in the country, but a systematic plan to cancer control is lacking....
Sat Aug 01, 2020 13:35
Related Articles Understanding American Indian Perceptions Toward Radiation Therapy. Cancer Control. 2020 Jul-Aug;27(3):1073274820945991 Authors: Patel SH, Ebrahimi S, Northfelt DW, Mathews TE, Omar FM, Martinez ED, DeWees TA, Okamoto JM Abstract Many American Indian (AI) and Alaska native (AN) patients do not complete guideline-concordant cancer care for the 4 most common cancers. Our aim was to better understand AI/AN attitudes toward...
Sat Aug 01, 2020 13:35
Related Articles The Changes in Pharyngeal Constrictor Muscles Related to Head and Neck Radiotherapy: A Systematic Review. Technol Cancer Res Treat. 2020 Jan-Dec;19:1533033820945805 Authors: Grepl J, Sirak I, Vosmik M, Tichy A Abstract It is well known that radiation damage of the pharyngeal constrictor muscles, the glottic larynx, and the supraglottic larynx may lead to dysphagia, an unwanted effect of head and neck radiotherapy. The reduction...
Sat Aug 01, 2020 13:35
Related Articles Trastuzumab emtansine: a game changer in HER2-positive early breast cancer. Future Oncol. 2020 Jul 31;: Authors: S Mano M Abstract Trastuzumab emtansine (T-DM1), given postoperatively for 14 cycles to patients with human epidermal growth factor receptor 2-positive (HER2-positive) early breast cancer (EBC) who failed to achieve a pathological complete response after standard chemotherapy and HER2 blockade, represents probably...
Sat Aug 01, 2020 13:35
Related Articles 18F-FDG PET and DCE kinetic modeling and their correlations in primary NSCLC: first voxel-wise correlative analysis of human simultaneous [18F]FDG PET-MRI data. EJNMMI Res. 2020 Jul 30;10(1):88 Authors: Besson FL, Fernandez B, Faure S, Mercier O, Seferian A, Mignard X, Mussot S, le Pechoux C, Caramella C, Botticella A, Levy A, Parent F, Bulifon S, Montani D, Mitilian D, Fadel E, Planchard D, Besse B, Ghigna-Bellinzoni MR, Comtat C, Lebon V,...
Sat Aug 01, 2020 13:35
Related Articles Prostate-specific membrane antigen targeted PET imaging for prostate cancer recurrence. Curr Opin Urol. 2020 Jul 23;: Authors: Ferdinandus J, Fendler WP, Hadaschik B, Herrmann K Abstract PURPOSE OF REVIEW: Prostate-specific membrane antigen targeted PET imaging (PSMA PET) of biochemically recurrent prostate cancer (BCR) is implemented in routine management in many countries and recommended in European Association of Urology...
Sat Aug 01, 2020 13:35
Related Articles Impact of nonspecific death on overall survival in early-stage epithelial ovarian cancer patients. Curr Probl Cancer. 2020 Jul 18;:100621 Authors: Dai D, Deng T, Wang B, Chen S, Liu Z, Luo X, Wang F, Huang H, Liu J Abstract OBJECTIVE: To estimate the impacts of nonovarian cancer-specific death (non-OCSD) and ovarian cancer-specific death (OCSD) on early-stage patients, and to determine which statistical method yielded survival...
Sat Aug 01, 2020 13:35
Related Articles Impact of COVID-19 on early career scientists: an optimistic guide for the future. BMC Biol. 2020 Jul 30;18(1):95 Authors: Termini CM, Traver D PMID: 32731867 [PubMed - in process]
Sat Aug 01, 2020 13:35
Related Articles Inflammatory Biomarkers and Breast Cancer Risk: A Systematic Review of the Evidence and Future Potential for Intervention Research. Int J Environ Res Public Health. 2020 Jul 28;17(15): Authors: Kehm RD, McDonald JA, Fenton SE, Kavanaugh-Lynch M, Leung KA, McKenzie KE, Mandelblatt JS, Terry MB Abstract Measuring systemic chronic inflammatory markers in the blood may be one way of understanding the role of inflammation in...
Sat Aug 01, 2020 13:35
Related Articles Study of the Female Sex Survival Advantage in Melanoma-A Focus on X-Linked Epigenetic Regulators and Immune Responses in Two Cohorts. Cancers (Basel). 2020 Jul 28;12(8): Authors: Emran AA, Nsengimana J, Punnia-Moorthy G, Schmitz U, Gallagher SJ, Newton-Bishop J, Tiffen JC, Hersey P Abstract BACKGROUND: Survival from melanoma is strongly related to patient sex, with females having a survival rate almost twice that of males....
Sat Aug 01, 2020 13:35
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