Healthcare is battling a conflict between the Quadruple Aims—reducing costs; improving population health, patient experience, and team well-being—and productivity. This quasi-experimental pilot study tested a ...
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Abstract There is ample evidence that violations of injunctive norms impact ordinary causal attributions. This has struck some as deeply surprising, taking the ordinary concept of causation to be purely descriptive. Our explanation of the findings—the responsibility view—rejects this: we contend that the concept is in fact partly normative, being akin to concepts like responsibility and accountability. Based on this account, we predicted a very different pattern of results for...
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Researchers examined the plant life in the China's Hengduan Mountains, the Himalaya Mountains, and the Qinghai-Tibet Plateau. Using DNA to build family trees of species, they learned that the diversity of plants in that region today can be traced back to newly-formed mountain ranges 30 million years ago, and monsoons that came later. It's a concrete example of how climatic and environmental changes influence life on Earth.
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Researchers have investigated the phenomenon of sexual parasitism in deep-sea anglerfish. The scientists show that this very rare mode of reproduction is associated with the loss of adaptive immunity. In the course of evolution, however, the animals have reorganized their immune systems and only survive with the help of their innate immunity.
Biologists have achieved the first gene knockout in a cephalopod using the squid Doryteuthis pealeii, an exceptionally important research organism in biology for nearly a century. The team used CRISPR-Cas9 genome editing to knock out a pigmentation gene in squid embryos, which eliminated pigmentation in the eye and in skin cells (chromatophores) with high efficiency.
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Abstract Objective To compare the classification of the adequacy of birth weight for gestational age applying INTERGROWTH-21 (IG-21) and Fenton growth curves in preterm infants, and to relate this classification to the nutritional status at 12 months corrected age. Methods This is a retrospective study with 173 preterm infants aged between 26 and 33 weeks....
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Publication date: Available online 31 July 2020Source: CortexAuthor(s): Kimberly D. Mueller, Rebecca L. Koscik, Lianlian Du, Davide Bruno, Erin M. Jonaitis, Audra Z. Koscik, Bradley T. Christian, Tobey J. Betthauser, Nathaniel A. Chin, Bruce P. Hermann, Sterling C. Johnson
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Thoracic trauma (TT) is the third most common cause of death after abdominal injury and head trauma in polytrauma patients. Its management is still a very challenging task. The purpose of this study was to ana...
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Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on ethyl cellulose as a feed additive for all animal species. Ethyl cellulose is intended for use as a technological additive (functional group: stabiliser) in premixtures and feedingstuffs for all animal species with no minimum and maximum content. A proper identification and characterisation of ethyl cellulose as required...
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on hydroxypropyl methyl cellulose as a feed additive for all animal species. Hydroxypropyl methyl cellulose is intended for use as a technological additive (functional group: stabiliser) in premixtures and feedingstuffs for all animal species with no minimum and maximum content. A proper identification and characterisation...
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on hydroxypropyl cellulose as a feed additive for all animal species. Hydroxypropyl cellulose is intended for use as a technological additive (functional groups: emulsifier, stabiliser and thickener) in premixtures and feedingstuffs for all animal species with no minimum and maximum content. A proper identification and...
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on methyl cellulose as a feed additive for all animal species. Methyl cellulose is intended for use as a technological additive (functional groups: emulsifier, stabiliser, thickener, gelling agent and binder) in premixtures and feedingstuffs for all animal species with no minimum and maximum content. A proper identification...
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on sodium carboxymethyl cellulose as a feed additive for all animal species. Sodium carboxymethyl cellulose is intended for use as a technological additive (functional groups: emulsifier, stabiliser, thickener, gelling agent and binder) in premixtures and feedingstuffs for all animal species with no minimum and maximum...
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on microcrystalline cellulose as a feed additive for all animal species. Microcrystalline cellulose is intended for use as a technological additive (functional groups: emulsifier, stabiliser, thickener, gelling agent and binder) in premixtures and feedingstuffs for all animal species with no minimum and maximum content....
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA ) was asked to deliver an opinion on the safety of rapeseed powder from Brassica rapa L. and Brassica napus L. as a novel food (NF ) pursuant to Regulation (EU ) 2015/2283. Rapeseed powder will be produced from the seeds of non‐genetically modified double low (00) cultivars that are varieties with a low content of erucic acid and reduced content of glucosinolates compared...
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Abstract Purpose Patients with obstructive sleep apnea syndrome (OSAS) have been found to exhibit lower serum vitamin D levels, even when the control groups are matched for confounding conditions. However, contradictory studies are also present. This study aimed to compare serum 25-hydroxyvitamin D (25(OH)D) levels between adult patients with OSAS and non-apneic controls and to evaluate the changes in 25(OH)D levels after 3 and 12 months...
Abstract Purpose Cardiac and respiratory involvement constitutes serious complications of Duchenne muscular dystrophy (DMD). We hypothesized that obstructive sleep apnea syndrome (OSAS) may play a role in cardiac autonomic dysfunction in DMD. We sought to assess the presence of cardiac autonomic function in patients with DMD by analyzing heart rate variability (HRV) during polysomnography (PSG). ...
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Abstract Background Effects of resistance training on muscle strength and hypertrophy are well established in adults and younger elderly. However, less is currently known about these effects in the very elderly (i.e., 75 years of age and older). Objective To examine the effects of resistance training on muscle size and strength in very elderly individuals....
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Objectives: This study tested the hypothesis that undetected peripheral hearing impairment occurs in children with idiopathic listening difficulties (LiDs), as reported by caregivers using the Evaluation of Children”s Listening and Processing Skills (ECLiPS) validated questionnaire, compared with children with typically developed (TD) listening abilities. Design: Children with LiD aged 6–14 years old (n = 60, mean age = 9.9 yr) and 54 typical age matched children were recruited from audiology...
Objectives: This study examines the unique factors that influence loss to follow-up after newborn hearing screening for patients at a Massachusetts urban safety-net hospital. We seek to characterize our patient population, investigate correlations between patient factors and rates of follow-up, and understand gaps in care. Design: A retrospective chart review was conducted of patients born at an urban safety-net hospital from January 2015 through May 2018 who did not pass the newborn hearing...
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Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. It is well known that radiation damage of the pharyngeal constrictor muscles, the glottic larynx, and the supraglottic larynx may lead to dysphagia, an unwanted effect of head and neck radiotherapy. The reduction of radiotherapy-induced dysphagia might be achieved by adaptive radiotherapy. Although the number of studies concerning adaptive radiotherapy of head and neck cancer is continuously increasing, there...
Fri Jul 31, 2020 15:00
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Background:There are very few studies on noncoplanar radiation in tomotherapy because deformable image registration is not implemented in the TomoTherapy Planning Station, a treatment planning device used in tomotherapy. This study examined whether noncoplanar radiation can be performed on the head using a tilt-type head and neck fixture and deformable image registration.Methods:Planning target volume spheres...
Fri Jul 31, 2020 14:59
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Glioma is a common type of tumor in human central nervous system, and it is characterized with high mobility and mortality. The prognosis of patients with advanced glioma remains poor. Thus, it is necessary to develop novel therapeutic approaches for the treatment of this disease. Circular RNAs are a group of noncoding RNAs which have been detected in eukaryotic cells. They are tissue-specific and characterized...
Thu Jul 30, 2020 13:23
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Chloroplast genome sequence data is very useful in studying/addressing the phylogeny of plants at various taxonomic ranks. However, there are no empirical observations on the patterns, directions, and mutation...
Adaptive radiations are characterized by extreme and/or iterative phenotypic divergence; however, such variation does not accumulate evenly across an organism. Instead, it is often partitioned into sub-units, ...
An amendment to this paper has been published and can be accessed via the original article.
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Journal of International Medical Research, Volume 48, Issue 7, July 2020. Diquat is a nonselective herbicide that is used as a contact and preharvest desiccant to control terrestrial and aquatic vegetation. Increasing numbers of cases of diquat poisoning have recently been reported. Organs commonly affected by diquat poisoning include the kidney, liver, and lung. Neurological involvement of diquat poisoning is relatively rare. A 21-year-old man ingested 100 mL of diquat (20 g/100 mL) 5 hours before...
Fri Jul 31, 2020 14:18
Journal of International Medical Research, Volume 48, Issue 7, July 2020. PurposeTo investigate the efficacy of combining the dopamine receptor agonist pramipexole with levodopa for Parkinson’s disease (PD) treatment and to measure their effects on quality of life and tumor necrosis factor (TNF)-α levels in PD patients.Basic ProcedureIn total, 160 PD patients who were admitted to our hospital were equally randomized into a control treatment group (levodopa alone) and the study group (pramipexole...
Fri Jul 31, 2020 11:46
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThe predictive value of red blood cell distribution width (RDW) in patients in the coronary care unit (CCU) remains unknown. This study aimed to examine the prognostic value of RDW in these patients.MethodsClinical data were extracted from the Medical Information Mart for Intensive Care-III database. Baseline data were collected within 24 hours after patients’ first admission to the CCU. The outcomes of our study were...
Fri Jul 31, 2020 10:42
Journal of International Medical Research, Volume 48, Issue 7, July 2020. Emphysematous cystitis (EC) is a rare bladder infection characterized by the presence of gas in the wall or cavity of the bladder. Most patients with EC will present with the typical symptoms of cystitis (e.g. frequent micturition, urgent micturition and dysuria), but other signs include distension and pain in the lower abdomen, drum sounds on percussion and a large amount of gas in the bladder. There can also be other complications...
Thu Jul 30, 2020 09:44
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectivesTo detect the involvement of immune cells in the pathogenesis of endometriosis in patients with stable status or pelvic pain.MethodsBlood was collected from patients with endometriosis with and without pelvic pain. Natural killer (NK) and Th17 cells were analyzed by flow cytometry, and secretion of inflammatory cytokines (tumor necrosis factor-α, interleukin (IL)-1β, IL-6, IL-7) was verified by enzyme-linked immunosorbent...
Thu Jul 30, 2020 09:44
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThis study aimed to characterize the ultrasound (US) imaging features of breast tuberculosis (BTB) to clarify the process of disease progression and provide valuable clinical information.MethodsWe retrospectively reviewed 45 patients with pathologically or GeneXpert-confirmed BTB from January 2010 to December 2017. We assessed the US features of target lesions including size, shape, orientation, margin, echogenicity,...
Thu Jul 30, 2020 09:43
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Introgression from wild relatives is a valuable source of novel allelic diversity for breeding. We investigated the genomic patterns of introgression from Aegilops tauschii, the diploid ancestor of the wheat D genome, into winter wheat (Triticum aestivum) cultivars. The population of 351 BC1F3:5 lines was selected based on phenology from crosses between six hexaploid wheat lines and 21 wheat-Ae. tauschii octoploids. SNP markers developed for this population and a diverse panel of 116 Ae. tauschii...
Genetic approaches in Drosophila have successfully identified many genes involved in regulation of growth control as well as genetic interactions relevant to the initiation and progression of cancer in vivo. Here, we report on large-scale RNAi-based screens to identify potential tumor suppressor genes that interact with known cancer-drivers: the Epidermal Growth Factor Receptor and the Hippo pathway transcriptional cofactor Yorkie. These screens were designed to identify genes whose depletion drove...
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Since December 2019, an outbreak of Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) initially emerged in Wuhan, China, and has spread worldwide no...
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