Related Articles Pediatric Prehospital Airway Management by U.S. Forces in Iraq and Afghanistan. Mil Med. 2020 Aug 05;: Authors: Koslow EA, Borgman MA, April MD, Schauer SG Abstract INTRODUCTION: Airway obstruction is a treatable cause of potentially preventable death on the battlefield. Emergency cricothyrotomies are rarely performed in developed countries, but are a common prehospital procedure in recent conflicts in Iraq and Afghanistan....
Related Articles Combat Facial Fractures Sustained During Operation Resolute Support and Operation Freedom's Sentinel in Afghanistan. Mil Med. 2020 Aug 05;: Authors: Breeze J, Gensheimer W, DuBose JJ Abstract INTRODUCTION: Facial fractures sustained in combat are generally unrepresentative of those commonly experienced in civilian practice. In the US military, acute trauma patient care is guided by the Joint Trauma System Clinical Practice Guidelines...
Related Articles An analysis of radial pulse strength to recorded blood pressure in the Department of Defense Trauma Registry. Mil Med. 2020 Aug 05;: Authors: Naylor JF, Fisher AD, April MD, Schauer SG Abstract INTRODUCTION: Hemorrhage is the leading cause of potentially preventable death on the battlefield. The tactical combat casualty care guidelines recommend the use of the radial pulse strength to guide the administration of blood products...
Related Articles Workforce Planning for Embedded Mental Health Care in the U.S. Navy. Mil Med. 2020 Aug 05;: Authors: Millegan J, Lippy R, De La Rosa G, Swayze M, Murray T, Hucles K, Webb-Murphy J, Bhakta J, Delaney E, Pauli I, Buenviaje B Abstract INTRODUCTION: Embedding mental health providers directly into operational units provides opportunities for holistic individual and population focused mental health support. To effectively provide...
Related Articles Why Shifting Mindset Matters. Mil Med. 2020 Aug 05;: Authors: Woo JJY Abstract The transformation to health and readiness for individuals and organizations, while structured in common strategies, metrics, and process improvement frameworks, used throughout healthcare, will not be achieved or sustained without a shift in mindset. PMID: 32754729 [PubMed - as supplied by publisher]
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Related Articles LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN. Histol Histopathol. 2020 Aug 05;:18245 Authors: Li Y, Zhang M, Li F Abstract Breast cancer remains a major challenge despite dramatic advances in cancer research. The long non-coding RNA (lncRNA) has been reported to associate with carcinogenesis and progression of various cancers. In this research, we found that...
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Related Articles Role of key point Mutations in Receptor Binding Domain of SARS-CoV-2 Spike Glycoprotein. Infect Disord Drug Targets. 2020 Aug 04;: Authors: Singh B Abstract The recent outbreak of novel coronavirus (SARS-CoV-2 or 2019-nCoV) and its worldwide spread is posing one of the major threats to human health and the world economy. It has been suggested that SARS-CoV-2 is similar to SARSCoV based on the comparison of the genome sequence....
Related Articles Scientometric Analysis of Global Research on Trichomoniasis in Scopus Database (1922 -2018). Infect Disord Drug Targets. 2020 Aug 04;: Authors: Keighobadi M, Hezarjaribi HZ, Khasseh AA, Soosaraei M, Asadi S, Fakhar M Abstract BACKGROUND: Trichomoniasis is a sexually transmitted disease (STD) prevalent in different parts of the world. The present study was designed to evaluate the scientific output and collaboration of researchers...
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Related Articles Correction. J Dermatolog Treat. 2020 Aug 05;:1 Authors: PMID: 32752899 [PubMed - as supplied by publisher]
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Related Articles Cyclin D1 Expression in Patients with Laryngeal Squamous Cell Carcinoma. Iran J Pathol. 2020;15(3):245-250 Authors: Zand V, Binesh F, Meybodian M, Safi Dahaj F, Alamdar Yazdi A Abstract Background & Objective: Laryngeal squamous cell carcinoma (LSCC) is considered to be one of the most common cancers of the head and neck, accounting for roughly 90% of all malignant tumors of the larynx. To have a timely diagnosis for a better...
Related Articles Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation. Cell Rep. 2019 06 04;27(10):2837-2846.e4 Authors: van den Berg MCW, MacCarthy-Morrogh L, Carter D, Morris J, Ribeiro Bravo I, Feng Y, Martin P Abstract Cancer-related inflammation impacts significantly on cancer development and progression. From early stages, neutrophils and macrophages are drawn to pre-neoplastic...
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Related Articles Spontaneous intracranial hypotension associated with cerebral venous thrombosis detected by a sudden seizure: a case report. JA Clin Rep. 2020 Aug 04;6(1):59 Authors: Yamamoto A, Hattammaru Y, Uezono S Abstract BACKGROUND: Spontaneous intracranial hypotension (SIH) is rare but can lead to life-threatening complications including cerebral venous thrombosis (CVT). The concurrence of CVT and SIH raises questions regarding priority....
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Related Articles Barriers and facilitators to CDH1 carriers contemplating or undergoing prophylactic total gastrectomy. Fam Cancer. 2020 Aug 05;: Authors: McGarragle KM, Hart TL, Swallow C, Brar S, Govindarajan A, Cohen Z, Aronson M Abstract Hereditary diffuse gastric cancer (HDGC) is an inherited cancer syndrome associated with high lifetime risk of diffuse-type gastric cancer. Current guidelines recommend individuals with HDGC undergo prophylactic...
Related Articles The importance of circulating and disseminated tumor cells in pancreatic cancer. Surg Open Sci. 2019 Oct;1(2):49-55 Authors: Hasanain A, Blanco BA, Yu J, Wolfgang CL Abstract Pancreatic cancer is a lethal disease in a large part due to the systemic nature at the time of diagnosis. In those patients who undergo a potentially curative resection of pancreatic cancer, the overwhelming majority will have systemic relapse. Circulating...
Related Articles Serum piRNA-54265 is a New Biomarker for early detection and clinical surveillance of Human Colorectal Cancer. Theranostics. 2020;10(19):8468-8478 Authors: Mai D, Zheng Y, Guo H, Ding P, Bai R, Li M, Ye Y, Zhang J, Huang X, Liu D, Sui Q, Pan L, Su J, Deng J, Wu G, Li R, Deng S, Bai Y, Ligu Y, Tan W, Wu C, Wu T, Zheng J, Lin D Abstract Background: Our previous study has demonstrated an oncogenic role of PIWI-interacting RNA-54265...
Related Articles A cohort study and meta-analysis of the evidence for consideration of Lauren subtype when prescribing adjuvant or palliative chemotherapy for gastric cancer. Ther Adv Med Oncol. 2020;12:1758835920930359 Authors: Wang K, Li E, Busuttil RA, Kong JC, Pattison S, Sung JJY, Yu J, El-Omar EM, Simpson JA, Boussioutas A Abstract Background: The association between the survival or efficacy of chemotherapy and the Lauren subtype of gastric...
Related Articles PD-1 does not mark tumor-infiltrating CD8+ T cell dysfunction in human gastric cancer. J Immunother Cancer. 2020 Aug;8(2): Authors: Shen Y, Teng Y, Lv Y, Zhao Y, Qiu Y, Chen W, Wang L, Wang Y, Mao F, Cheng P, Ma D, Zhuang Y, Zou Q, Peng L Abstract BACKGROUND: Overexpression of programmed cell death protein 1 (PD-1) is linked to CD8+ T cell dysfunction and contributes to tumor immune escape. However, the prevalence and functional...
Related Articles Proton therapy and the European Particle Therapy Network: The past, present and future. Cancer Radiother. 2020 Aug 01;: Authors: Weber DC, Langendijk JA, Grau C, Thariat J Abstract Proton therapy is delivered to selected cancer patients presenting with rare tumours, for which a dose escalation paradigm and/or a reduced dose-bath to the organs at risk is pursued. It is a costly treatment with an additional cost factor of 2-3...
Related Articles Evaluation of Salmon, Tuna, and Beef Freshness Using a Portable Spectrometer. Sensors (Basel). 2020 Aug 01;20(15): Authors: Moon EJ, Kim Y, Xu Y, Na Y, Giaccia AJ, Lee JH Abstract There has been strong demand for the development of an accurate but simple method to assess the freshness of food. In this study, we demonstrated a system to determine food freshness by analyzing the spectral response from a portable visible/near-infrared...
Related Articles Objective Olfactory Findings in Hospitalized Severe COVID-19 Patients. Pathogens. 2020 Jul 31;9(8): Authors: Lechien JR, Ducarme M, Place S, Chiesa-Estomba CM, Khalife M, De Riu G, Vaira LA, de Terwangne C, Machayekhi S, Marchant A, Journe F, Saussez S Abstract OBJECTIVE: We investigate the prevalence of the self-reported and objective sudden loss of smell (SLS) in patients with severe coronavirus disease 2019 (COVID-19). ...
Related Articles Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups. Int J Mol Sci. 2020 Jul 31;21(15): Authors: Nedoszytko B, Sobalska-Kwapis M, Strapagiel D, Lange M, Górska A, Elberink JNGO, van Doormaal J, Słomka M, Kalinowski L, Gruchała-Niedoszytko M, Nowicki RJ, Valent P, Niedoszytko M Abstract Mastocytosis is rare disease in which genetic predisposition is not...
Related Articles Molecular Biology of Osteosarcoma. Cancers (Basel). 2020 Jul 31;12(8): Authors: Czarnecka AM, Synoradzki K, Firlej W, Bartnik E, Sobczuk P, Fiedorowicz M, Grieb P, Rutkowski P Abstract Osteosarcoma (OS) is the most frequent primary bone cancer in children and adolescents and the third most frequent in adults. Many inherited germline mutations are responsible for syndromes that predispose to osteosarcomas including Li Fraumeni...
Related Articles Selected Matrix Metalloproteinases (MMP-2, MMP-7) and Their Inhibitor (TIMP-2) in Adult and Pediatric Cancer. Diagnostics (Basel). 2020 Jul 31;10(8): Authors: Kaczorowska A, Miękus N, Stefanowicz J, Adamkiewicz-Drożyńska E Abstract The tumor microenvironment (TME) consists of numerous biologically relevant elements. One of the most important components of the TME is the extracellular matrix (ECM). The compounds of the ECM create...
Related Articles Genomic Database Analysis of Uterine Leiomyosarcoma Mutational Profile. Cancers (Basel). 2020 Jul 31;12(8): Authors: Astolfi A, Nannini M, Indio V, Schipani A, Rizzo A, Perrone AM, De Iaco P, Pirini MG, De Leo A, Urbini M, Secchiero P, Pantaleo MA Abstract Uterine Leiomyosarcoma (uLMS) is by far the most common type of uterine sarcoma, characterized by an aggressive clinical course, a heterogeneous genetic profile and a very...
Related Articles Osteosarcoma-Derived Extracellular Vesicles Induce Lung Fibroblast Reprogramming. Int J Mol Sci. 2020 Jul 30;21(15): Authors: Mazumdar A, Urdinez J, Boro A, Migliavacca J, Arlt MJE, Muff R, Fuchs B, Snedeker JG, Gvozdenovic A Abstract Tumor-secreted extracellular vesicles (EVs) have been identified as mediators of cancer-host intercellular communication and shown to support pre-metastatic niche formation by modulating stromal...
Related Articles The Development of a Skin Cancer Classification System for Pigmented Skin Lesions Using Deep Learning. Biomolecules. 2020 Jul 29;10(8): Authors: Jinnai S, Yamazaki N, Hirano Y, Sugawara Y, Ohe Y, Hamamoto R Abstract Recent studies have demonstrated the usefulness of convolutional neural networks (CNNs) to classify images of melanoma, with accuracies comparable to those achieved by dermatologists. However, the performance of...
Related Articles Personal Medicine and Bone Metastases: Biomarkers, Micro-RNAs and Bone Metastases. Cancers (Basel). 2020 Jul 29;12(8): Authors: Wood SL, Brown JE Abstract Bone metastasis is a major cause of morbidity within solid tumours of the breast, prostate, lung and kidney. Metastasis to the skeleton is associated with a wide range of complications including bone fractures, spinal cord compression, hypercalcaemia and increased bone pain....
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Related Articles Baicalin inhibits the TGF-β1/p-Smad3 pathway to suppress epithelial-mesenchymal transition-induced metastasis in breast cancer. Oncotarget. 2020 Jul 21;11(29):2863-2872 Authors: Liu DK, Dong HF, Liu RF, Xiao XL Abstract TGF-β1 is an epithelial-mesenchymal transition (EMT)-inducing factor that is critical in tumor progression. However, whether the effect of TGF-β1 on breast cancer is through the EMT pathway remains to be...
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Related Articles Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation. Oncotarget. 2020 Jul 21;11(29):2847-2862 Authors: Domvri K, Petanidis S, Anestakis D, Porpodis K, Bai C, Zarogoulidis P, Freitag L, Hohenforst-Schmidt W, Katopodi T Abstract Immunosuppressive chemoresistance is a major burden in lung cancer. Recent data reveal that long noncoding RNAs...
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Related Articles Therapeutic efficacy of liposomal Grb2 antisense oligodeoxynucleotide (L-Grb2) in preclinical models of ovarian and uterine cancer. Oncotarget. 2020 Jul 21;11(29):2819-2833 Authors: Lara OD, Bayraktar E, Amero P, Ma S, Ivan C, Hu W, Wang Y, Mangala LS, Dutta P, Bhattacharya P, Ashizawa AT, Lopez-Berestein G, Rodriguez-Aguayo C, Sood AK Abstract BACKGROUND: Adaptor proteins such as growth factor receptor-bound protein-2...
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Related Articles Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients. Oncotarget. 2020 Jul 21;11(29):2807-2818 Authors: Rosenberg MW, Watanabe-Smith K, Tyner JW, Tognon CE, Druker BJ, Borate U Abstract Acute myeloid leukemia (AML) is a heterogeneous malignancy with the most common genomic alterations in NPM1, DNMT3A, and FLT3. Midostaurin was the first FLT3 inhibitor FDA approved...
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