Related Articles Hypercalcemia Resulting from Necrotizing Leiomyoma in a Pregnant Female. Am J Case Rep. 2020 Aug 05;21:e923412 Authors: Kropf J, Vo M, Cheyney S, Kayaleh O, McWhorter J, Carlan SJ Abstract BACKGROUND Hypercalcemic crisis is defined as a serum calcium level >14 mg/dL in a symptomatic patient. While severe hypercalcemia during pregnancy is rare, it poses a life-threatening risk to both mother and fetus. Hypercalcemia in association...
Thu Aug 06, 2020 15:38
Related Articles Preliminary Clinical Trial of Balance Compensation System for Improvement of Balance in Patients With Spinocerebellar Ataxia. Ann Rehabil Med. 2020 Aug 05;: Authors: Hong JS, Kim JH, Yong SY, Lee YH, Kim SH, Park JY, Lee JK, Jang JY Abstract Objective: To determine the immediate and short-term impact of the application of wearable balance compensation system (BCS) on balance impairment in patients with spinocerebellar ataxia...
Thu Aug 06, 2020 16:45
Related Articles Relationship Between Line Bisection Test Time and Hemispatial Neglect Prognosis in Patients With Stroke: A Prospective Pilot Study. Ann Rehabil Med. 2020 Aug 05;: Authors: Kwon S, Park W, Kim M, Kim JM Abstract Objective: To determine the relationship between line bisection test (LBT) performance time and prognosis of hemispatial neglect (HSN) in stroke patients. Methods: Data on stroke patients with HSN were prospectively...
Thu Aug 06, 2020 16:45
Related Articles Mechanism of phthalate esters in the progression and development of breast cancer. Drug Chem Toxicol. 2020 Aug 04;:1-5 Authors: Mughees M, Chugh H, Wajid S Abstract Phthalate esters are produced widely for their use as plasticizer in consumer products such as cosmetics, PVC, deodorants etc. Their use is considered harmless but they are known to induce cancer and work as endocrine disruptors. In this review, we try to emphasize...
Thu Aug 06, 2020 17:59
Related Articles Methanol extracts of Teucrium arduini L. and Teucrium flavum L. induce protective effect against mitomycin C in human lymphocytes in vitro. Drug Chem Toxicol. 2020 Aug 04;:1-7 Authors: Marković A, Tubić Vukajlović J, Grujičić D, Radović Jakovljević M, Stanković M, Djordjević K, Djelić N, Radaković M, Milošević-Djordjević O Abstract The study was designed to evaluate antigenotoxic effect of methanol Teucrium arduini and Teucrium...
Thu Aug 06, 2020 17:59
Related Articles Health risk assessment of 42 pesticide residues in Tieguanyin tea from Fujian, China. Drug Chem Toxicol. 2020 Aug 04;:1-8 Authors: Yao Q, Yan SA, Li J, Huang M, Lin Q Abstract The objective of this study was to evaluate the residues of 42 pesticides subject to public concern in Tieguanyin tea produced in Fujian, China. The presence of 42 pesticide residues in 90 Tieguanyin tea samples were determined. A total of 17 pesticides...
Thu Aug 06, 2020 17:59
Related Articles Psychological Distress in Outpatients With Lymphoma During the COVID-19 Pandemic. Front Oncol. 2020;10:1270 Authors: Romito F, Dellino M, Loseto G, Opinto G, Silvestris E, Cormio C, Guarini A, Minoia C Abstract Cancer patients are a population at high risk of contracting COVID-19 and, also of developing severe complications due to the infection, which is especially true when they are undergoing immunosuppressive treatment. Despite...
Thu Aug 06, 2020 15:29
Related Articles Commentary: SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China. Front Oncol. 2020;10:1223 Authors: Di Cosimo S, Porcu L, Malfettone A, Cortés J, Miceli R PMID: 32754446 [PubMed]
Thu Aug 06, 2020 15:29
Related Articles Nilotinib-Induced Immune-Mediated Liver Injury: Corticosteroid as a Possible Therapeutic Option. Front Oncol. 2020;10:1160 Authors: Yang H, Sung PS, Jung ES, Cho S, Bae SH, Kim DW Abstract Introduction: Nilotinib is a BCR-ABL tyrosine kinase inhibitor approved for chronic myeloid leukemia. We present a case of severe immune-mediated liver injury by nilotinib treatment. Case report: A 59-year-old woman was referred to the liver...
Thu Aug 06, 2020 15:29
Related Articles Cytosolic NUAK1 Enhances ATP Production by Maintaining Proper Glycolysis and Mitochondrial Function in Cancer Cells. Front Oncol. 2020;10:1123 Authors: Escalona E, Muñoz M, Pincheira R, Elorza ÁA, Castro AF Abstract NUAK1 is an AMPK-related kinase located in the cytosol and the nucleus, whose expression associates with tumor malignancy and poor patient prognosis in several cancers. Accordingly, NUAK1 was associated with metastasis...
Thu Aug 06, 2020 15:29
Related Articles Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer. Front Oncol. 2020;10:1113 Authors: Ding XQ, Wang ZY, Xia D, Wang RX, Pan XR, Tong JH Abstract Background: Clinical management of metastatic gastric cancer (mGC) remains a major challenge due to a lack of specific biomarkers and effective therapeutic targets. Recently, accumulating evidence has suggested that exosomes play an essential role in...
Thu Aug 06, 2020 15:29
Related Articles Long Non-Coding RNA MNX1-AS1 Promotes Progression of Triple Negative Breast Cancer by Enhancing Phosphorylation of Stat3. Front Oncol. 2020;10:1108 Authors: Li J, Li Q, Li D, Shen Z, Zhang K, Bi Z, Li Y Abstract Triple negative breast cancer (TNBC) accounts for less than a quarter of breast cancer but has the poorest survival outcome and is prone to relapse as well as metastasis due to its aggressiveness and lack of therapeutic...
Thu Aug 06, 2020 15:29
Related Articles STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway. Front Oncol. 2020;10:1102 Authors: Romeo MA, Gilardini Montani MS, Benedetti R, Santarelli R, D'Orazi G, Cirone M Abstract Oncosuppressor TP53 and oncogene STAT3 have been shown to engage an interplay in which they negatively influence each other. Conversely, mutant (mut) p53 may sustain STAT3 phosphorylation by displacing SH2 phosphatase...
Thu Aug 06, 2020 15:29
Related Articles A Rare Complex BRAF Mutation Involving Codon V600 and K601 in Primary Cutaneous Melanoma: Case Report. Front Oncol. 2020;10:1056 Authors: Consoli F, Barbieri G, Picciolini M, Medicina D, Bugatti M, Tovazzi V, Liserre B, Zambelli C, Zorzi F, Berruti A, Giurisato E, Vermi W Abstract BRAF is one of the most common mutated kinases detected in human cancer, particularly in cases of primary cutaneous melanomas (PCM). Mutations of...
Thu Aug 06, 2020 15:29
Related Articles Anlotinib Combined With Chemoradiotherapy Exhibits Significant Therapeutic Efficacy in Esophageal Squamous Cell Carcinoma. Front Oncol. 2020;10:995 Authors: Shi J, Zhang Y, Wang J, Li J, Li Z Abstract Objective: The aim of this study was to evaluate the safety and efficacy of anlotinib combined with chemoradiotherapy for treating esophageal squamous cell carcinoma (ESCC) using patient-derived xenografts (PDXs). Methods: PDX-bearing...
Thu Aug 06, 2020 15:29
Related Articles LIMD1 Increases the Sensitivity of Lung Adenocarcinoma Cells to Cisplatin via the GADD45α/p38 MAPK Signaling Pathway. Front Oncol. 2020;10:969 Authors: Zeng X, Wang H, He D, Jia W, Ma R Abstract Objective: To investigate the effect of LIM domain-containing protein 1 (LIMD1) on the sensitivity of lung adenocarcinoma cells to cisplatin and explore the mechanism. Methods: A549 and H1299 cells were transfected with lentivirus to...
Thu Aug 06, 2020 15:29
Related Articles Minimally Invasive Retrosternal Esophageal Bypass Using a Mid-Colon Esophagocoloplasty for Corrosive-Induced Esophageal Stricture. World J Surg. 2020 Aug 04;: Authors: Gurram RP, Kalayarasan R, Gnanasekaran S, Pottakkat B Abstract INTRODUCTION: Colonic bypass for corrosive-induced esophageal stricture is traditionally performed using an open approach. The laparoscopic mid-colon retrosternal esophageal bypass has not been previously...
Thu Aug 06, 2020 15:59
Related Articles Novel mechanistic targets of forkhead box Q1 transcription factor in human breast cancer cells. Mol Carcinog. 2020 Aug 05;: Authors: Kim SH, Hahm ER, Singh KB, Singh SV Abstract The transcription factor forkhead box Q1 (FoxQ1) is overexpressed in different solid tumors including breast cancer, but the mechanism underlying its oncogenic function is still not fully understood. In this study, we compared RNA-seq data from...
Thu Aug 06, 2020 13:01
Related Articles Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation. Oncotarget. 2020 Jul 21;11(29):2847-2862 Authors: Domvri K, Petanidis S, Anestakis D, Porpodis K, Bai C, Zarogoulidis P, Freitag L, Hohenforst-Schmidt W, Katopodi T Abstract Immunosuppressive chemoresistance is a major burden in lung cancer. Recent data reveal that long noncoding RNAs...
Thu Aug 06, 2020 13:01
Related Articles Overexpression of IGFBP5 Enhances Radiosensitivity Through PI3K-AKT Pathway in Prostate Cancer. Cancer Manag Res. 2020;12:5409-5418 Authors: Chen X, Yu Q, Pan H, Li P, Wang X, Fu S Abstract Background: Radiotherapy is the main treatment for localized prostate cancer. The therapeutic effects of radiotherapy are highly dependent on radiosensitivity of target tumors. Here, we investigated the impact of insulin-like growth...
Thu Aug 06, 2020 13:01
Related Articles Overexpression of LRRC59 Is Associated with Poor Prognosis and Promotes Cell Proliferation and Invasion in Lung Adenocarcinoma. Onco Targets Ther. 2020;13:6453-6463 Authors: Li D, Xing Y, Tian T, Guo Y, Qian J Abstract Aim: LRRC59 (leucine-rich repeat-containing protein 59) is a ribosome-binding protein that also interacts with fibroblast growth factors. Limited investigations revealed a possible role of LRRC59 in the aggressive...
Thu Aug 06, 2020 13:01
Related Articles HIV Vpr Modulates the Host DNA Damage Response at Two Independent Steps to Damage DNA and Repress Double-Strand DNA Break Repair. mBio. 2020 Aug 04;11(4): Authors: Li D, Lopez A, Sandoval C, Nichols Doyle R, Fregoso OI Abstract The DNA damage response (DDR) is a signaling cascade that is vital to ensuring the fidelity of the host genome in the presence of genotoxic stress. Growing evidence has emphasized the importance...
Thu Aug 06, 2020 13:01
Related Articles Correction to: Urine cell cycle arrest biomarkers distinguish poorly between transient and persistent AKI in early septic shock: a prospective, multicenter study. Crit Care. 2020 Aug 04;24(1):483 Authors: Titeca-Beauport D, Daubin D, Van Vong L, Belliard G, Bruel C, Alaya S, Chaoui K, Andrieu M, Rouquette-Vincenti I, Godde F, Pascal M, Diouf M, Vinsonneau C, Klouche K, Maizel J Abstract An amendment to this paper has been...
Thu Aug 06, 2020 13:01
Related Articles Design, synthesis and biological evaluation of novel tetrahydrothieno [2,3-c]pyridine substitued benzoyl thiourea derivatives as PAK1 inhibitors in triple negative breast cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1524-1538 Authors: Yao D, Huang J, Wang J, He Z, Zhang J Abstract The overexpression of P21-activated kinase 1 (PAK1) is associated with poor prognosis in several cancers, which has emerged as a promising...
Thu Aug 06, 2020 13:01
Related Articles Standardized Saponin Extract from Baiye No.1 Tea (Camellia sinensis) Flowers Induced S Phase Cell Cycle Arrest and Apoptosis via AKT-MDM2-p53 Signaling Pathway in Ovarian Cancer Cells. Molecules. 2020 Jul 31;25(15): Authors: Tu Y, Chen L, Ren N, Li B, Wu Y, Rankin GO, Rojanasakul Y, Wang Y, Chen YC Abstract Ovarian cancer is considered to be one of the most serious malignant tumors in women. Natural compounds have been...
Thu Aug 06, 2020 13:01
Related Articles Cell Cycle Regulation in Macrophages and Susceptibility to HIV-1. Viruses. 2020 Jul 31;12(8): Authors: Ferreira IATM, Porterfield JZ, Gupta RK, Mlcochova P Abstract Macrophages are the first line of defence against invading pathogens. They play a crucial role in immunity but also in regeneration and homeostasis. Their remarkable plasticity in their phenotypes and function provides them with the ability to quickly respond...
Thu Aug 06, 2020 13:01
Related Articles Growth Inhibitory Signaling of the Raf/MEK/ERK Pathway. Int J Mol Sci. 2020 Jul 30;21(15): Authors: Wu PK, Becker A, Park JI Abstract In response to extracellular stimuli, the Raf/MEK/extracellular signal-regulated kinase (ERK) pathway regulates diverse cellular processes. While mainly known as a mitogenic signaling pathway, the Raf/MEK/ERK pathway can mediate not only cell proliferation and survival but also cell cycle...
Thu Aug 06, 2020 13:01
Related Articles Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer. Nat Commun. 2020 05 11;11(1):2350 Authors: Ge JY, Shu S, Kwon M, Jovanović B, Murphy K, Gulvady A, Fassl A, Trinh A, Kuang Y, Heavey GA, Luoma A, Paweletz C, Thorner AR, Wucherpfennig KW, Qi J, Brown M, Sicinski P, McDonald TO, Pellman D, Michor F, Polyak K Abstract BET inhibitors are promising therapeutic agents for the treatment of...
Thu Aug 06, 2020 13:01
Related Articles Changes in the EEG spectral power during dual-task walking with aging and Parkinson's disease: initial findings using Event-Related Spectral Perturbation analysis. J Neurol. 2020 Aug 04;: Authors: Possti D, Fahoum F, Sosnik R, Giladi N, Hausdorff JM, Mirelman A, Maidan I Abstract BACKGROUND: The ability to maintain adequate motor-cognitive performance under increasing task demands depends on the regulation and coordination of...
Thu Aug 06, 2020 13:26
Related Articles Knowledge, perceptions, and attitudes of students of health-related science colleges towards epilepsy in Taif, Saudi Arabia. J Family Med Prim Care. 2020 May;9(5):2394-2399 Authors: Kabel AM, Algethami SA, Algethami BS, Alzahrani AS, Almutairi SK, Almutairi AS Abstract Background: Epilepsy is one of the most common disorders that may be associated with negative attitudes among general populations. This may be due to poor public...
Thu Aug 06, 2020 13:26
Related Articles Gender Differences in Associated and Predictive Factors of Anxiety and Depression in People With Epilepsy. Front Psychiatry. 2020;11:670 Authors: Liu Z, Yin R, Fan Z, Fan H, Wu H, Shen B, Wu S, Kuang F Abstract Purpose: Comorbid anxiety and depression in people with epilepsy (PWE) are highly prevalent and contribute to low quality of life (QOL) and may even lead to poor outcomes of epilepsy. Among the various factors that affect...
Thu Aug 06, 2020 13:26
Related Articles A Case of Myoclonic Epilepsy Presenting with Status Epilepticus in an Elderly Male Patient. J Neurosci Rural Pract. 2020 Jul;11(3):463-466 Authors: Onder H Abstract Myoclonic epilepsy in the form of status epilepticus is an extremely rare reported presentation. Herein, we describe an 87-year old male patient presenting with abrupt-onset rhythmic myoclonic jerks that were evaluated as synchronous positive and negative myoclonus....
Thu Aug 06, 2020 13:26
Related Articles Prognosis of Pregnancy in Epileptics in Benin: A Case-Control Study. J Neurosci Rural Pract. 2020 Jul;11(3):395-402 Authors: Adoukonou T, Agbétou M, Sidi RI, Gnansounou C, Accrombessi D, Hounzangbe-Adoukonou Y, Gnonlonfoun D, Kabibou S, Tonato-Bagnan JA, Houinato D Abstract Objective The main purpose of this article is to define prognosis of pregnancies in epileptic women in Benin. Methods This was a case-control study that...
Thu Aug 06, 2020 13:26
Related Articles Distinguishing and Biochemical Phenotype Analysis of Epilepsy Patients Using a Novel Serum Profiling Platform. Brain Sci. 2020 Jul 31;10(8): Authors: Hanas JS, Hocker JRS, Vannarath C, Evangeline B, Prabhakaran V, Oommen A, Couch J, Anderson M, Rajshekhar V, Carabin H, Drevets D Abstract Diagnosis of non-symptomatic epilepsy includes a history of two or more seizures and brain imaging to rule out structural changes like trauma,...
Thu Aug 06, 2020 13:26
Related Articles Ivermectin Treatment Response in Onchocerca Volvulus Infected Persons with Epilepsy: A Three-Country Short Cohort Study. Pathogens. 2020 Jul 29;9(8): Authors: Dusabimana A, Bhwana D, Raimon S, Mmbando BP, Hotterbeekx A, Tepage F, Mandro M, Siewe Fodjo JN, Abrams S, Colebunders R Abstract Despite a long history of community-directed treatment with ivermectin (CDTI), a high ongoing Onchocerca volvulus transmission is observed...
Thu Aug 06, 2020 13:26
Related Articles Neurostimulation in the treatment of refractory and super-refractory status epilepticus. Epilepsy Behav. 2019 12;101(Pt B):106551 Authors: Trinka E, Brigo F Abstract Status epilepticus (SE) is a life-threatening condition with a mortality of up to 60% in the advanced and comatose forms of SE. In one out of five adults, first and second line fails to control epileptic activity, leading to refractory status epilepticus (RSE)...
Thu Aug 06, 2020 13:26
Related Articles Intravenous antiepileptic drugs in adults with benzodiazepine-resistant convulsive status epilepticus: A systematic review and network meta-analysis. Epilepsy Behav. 2019 12;101(Pt B):106466 Authors: Brigo F, Del Giovane C, Nardone R, Trinka E, Lattanzi S Abstract AIM: The aim of this study was to estimate the comparative efficacy and safety of antiepileptic drugs (AEDs) in adults with benzodiazepine-resistant convulsive status...
Thu Aug 06, 2020 13:26
Related Articles Valproate under threat. Aust N Z J Psychiatry. 2019 09;53(9):923 Authors: Vajda FJ PMID: 30848662 [PubMed - indexed for MEDLINE]
Thu Aug 06, 2020 13:26
Related Articles Olfaction Modulates Inter-Subject Correlation of Neural Responses. Front Neurosci. 2020;14:702 Authors: DeGuzman P, Jain A, Tabert MH, Parra LC Abstract Odors can be powerful stimulants. It is well-established that odors provide strong cues for recall of locations, people and events. The effects of specific scents on other cognitive functions are less well-established. We hypothesized that scents with different odor qualities...
Thu Aug 06, 2020 13:15
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